Properties of melt extruded enteric matrix pellets

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 74, Issue 2, 2010, Pages 352-361

  Schilling, Sandra U ^a   Shah, Navnit H ^b   Waseem Malick, A ^b   McGinity, James W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

Aqoat; Delayed release; Eudragit; Hot melt extrusion; Matrix pellets; Plasticizers

Indexed keywords

ACETYLTRIBUTYL CITRATE; AQOAT; BUFFER; CITRIC ACID; CITRIC ACID TRIBUTYL ESTER; CITRIC ACID TRIETHYL ESTER; EUDRAGIT; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; MACROGOL 8000; METHYL PARABEN; PLASTICIZER; POLYMER; THEOPHYLLINE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; DELAYED DRUG RELEASE; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PELLET; GLASS TRANSITION TEMPERATURE; MICROMORPHOLOGY; PARTICLE SIZE; PELLET EXTRUSION; POROSITY; REACTION TIME; ROOM TEMPERATURE; SCANNING ELECTRON MICROSCOPY; SLOW DRUG RELEASE; SOLID STATE; STOMACH PROTECTION; TEMPERATURE DEPENDENCE; VISCOSITY; X RAY DIFFRACTION;

CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG IMPLANTS; DRUG STABILITY; PARTICLE SIZE; PLASTICIZERS; POLYMERS; SOLUBILITY; SURFACE PROPERTIES; THEOPHYLLINE; TRANSITION TEMPERATURE; VISCOSITY;

EID: 75449085105     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.09.008     Document Type: Article

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