Properties of lipophilic matrix tablets containing phenylpropanolamine hydrochloride prepared by hot-melt extrusion

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 52, Issue 2, 2001, Pages 181-190

  Liu, Jiping ^a,c   Zhang, Feng ^b   McGinity, James W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b PharmaForm   (United States)

^c Sanofi Synthelabo Inc   (United Kingdom)

Author keywords

Hot melt extrusion; Matrix tablets; Melt granulation; Sustained release; Wax

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; EXCIPIENT; FILLER; GLYCEROL PALMITOSTEARATE; HPMC E4M; HPMC K15M; HPMC K4M; HYDROGENATED CASTOR OIL; HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; MICROCRYSTALLINE CELLULOSE; PHENYLPROPANOLAMINE; SOYBEAN OIL; STEROTEX; STEROTEX K; UNCLASSIFIED DRUG; WAX;

ARTICLE; COMPRESSION; CONTROLLED STUDY; DENSITY; DISSOLUTION; DRUG FORMULATION; DRUG GRANULE; DRUG RELEASE; DRUG SOLUBILITY; HARDNESS; HOT MELT EXTRUSION; LIPOPHILICITY; MATRIX TABLET; MELTING POINT; PARTICLE SIZE; PHYSICAL PARAMETERS; PHYSICAL PHENOMENA; POWDER; SUSTAINED RELEASE PREPARATION; TABLET;

ADRENERGIC ALPHA-AGONISTS; CHEMISTRY, PHARMACEUTICAL; COMPRESSIVE STRENGTH; DRUG CARRIERS; HEAT; PARTICLE SIZE; PHENYLPROPANOLAMINE; TABLETS; WAXES;

EID: 0034880292     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(01)00162-X     Document Type: Article

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