Improvement of the dissolution rate of poorly soluble drugs by solid crystal suspensions

Molecular Pharmaceutics

Volumn 8, Issue 3, 2011, Pages 727-735

  Thommes, Markus ^a,b   Ely, David R ^a   Carvajal, M Teresa ^a   Pinal, Rodolfo ^a  

^a PURDUE UNIVERSITY   (United States)

^b Institute of Pharmaceutics and Biopharmaceutics   (Germany)

Author keywords

amorphous; dissolution rate; extrusion; mannitol; solid crystal suspension; solid dispersion; solubility; stability

Indexed keywords

CRYSTALLIN; EXCIPIENT; GLASS; GRISEOFULVIN; MANNITOL; PHENYTOIN; SPIRONOLACTONE;

ARTICLE; DISSOLUTION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STORAGE; PARTICLE SIZE; PRIORITY JOURNAL; SOLID STATE; THERMOSTABILITY; WETTABILITY; X RAY DIFFRACTION;

DRUG STABILITY; PHARMACEUTICAL PREPARATIONS; SOLUBILITY; SUSPENSIONS; TEMPERATURE;

EID: 79958261591     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp1003493     Document Type: Article

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