Evaluation of solid state properties of solid dispersions prepared by hot-melt extrusion and solvent co-precipitation

International Journal of Pharmaceutics

Volumn 355, Issue 1-2, 2008, Pages 141-149

  Dong, Zedong ^a   Chatterji, Ashish ^a   Sandhu, Harpreet ^a   Choi, Duk Soon ^a   Chokshi, Hitesh ^a   Shah, Navnit ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

Hot melt extrusion; Physical characterization; Solid dispersion; Solvent co precipitation

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG COATING; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; GLASS TRANSITION TEMPERATURE; INFRARED SPECTROSCOPY; PRECIPITATION; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SCANNING ELECTRON MICROSCOPY; THERMAL ANALYSIS; WETTABILITY; X RAY DIFFRACTION;

CACO-2 CELLS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; DIFFERENTIAL THERMAL ANALYSIS; DRUG COMPOUNDING; EXCIPIENTS; HUMANS; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, POLARIZATION; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN; TEMPERATURE; X-RAY DIFFRACTION;

EID: 41349100668     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.017     Document Type: Article

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