Melt granulation using a twin-screw extruder: A case study

International Journal of Pharmaceutics

Volumn 326, Issue 1-2, 2006, Pages 89-93

  Van Melkebeke, Barbara ^a   Vermeulen, Brenda ^a   Vervaet, Chris ^a   Remon, Jean Paul ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Continuous granulation; Extruder; Melt agglomeration; Polyethylene glycol

Indexed keywords

CREMOPHOR; MACROGOL 400; MACROGOL 4000; POLYSORBATE 80; SURFACTANT;

ARTICLE; DISSOLUTION; DRUG FORMULATION; DRUG GRANULATION; DRUG RELEASE; DRUG SOLUBILITY; MELTING POINT; MICROENVIRONMENT; PRIORITY JOURNAL; X RAY DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYSORBATES; POWDERS; SOLUBILITY; SURFACE-ACTIVE AGENTS; TEMPERATURE; TIME FACTORS; WATER;

EID: 33750474421     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.07.005     Document Type: Article

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