Evaluation of polymer carriers with regard to the bioavailability enhancement of bifendate solid dispersions prepared by hot-melt extrusion

Drug Development and Industrial Pharmacy

Volumn 38, Issue 6, 2012, Pages 735-743

  Feng, Jia ^a   Xu, Lishuang ^a   Gao, Renchao ^a   Luo, Yanfei ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Bifendate; Bioavailability; Characterization; Hot melt extrusion; Polymer carriers; Related substance

Indexed keywords

BIFENDATE; BIPHENYL DERIVATIVE; CROSPOVIDONE; DRUG CARRIER; EUDRAGIT; LUDIPRESS; POLYMER; POVIDONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG BIOAVAILABILITY; DRUG DOSAGE FORM; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; MALE; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; STOMACH JUICE; THERMAL ANALYSIS; X RAY POWDER DIFFRACTION;

ANIMALS; BIOLOGICAL AVAILABILITY; BIPHENYL COMPOUNDS; DOGS; DRUG CARRIERS; DRUG COMPOUNDING; HOT TEMPERATURE; POLYMERS; SOLUBILITY;

EID: 84860385670     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.623703     Document Type: Article

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