Characterization of thermal and rheological properties of zidovidine, lamivudine and plasticizer blends with ethyl cellulose to assess their suitability for hot melt extrusion

European Journal of Pharmaceutical Sciences

Volumn 44, Issue 4, 2011, Pages 471-478

  Maru, Shital M ^a,b   De Matas, Marcel ^b,c   Kelly, Adrian ^b   Paradkar, Anant ^b  

^a UNIVERSITY OF NAIROBI   (Kenya)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Ethyl cellulose; Glass transition temperature; Lamivudine; Rheology; Solubility parameter; Zidovudine

Indexed keywords

ETHYL CELLULOSE; LAMIVUDINE; MACROGOL 6000; PLASTICIZER; TRIETHYLCITRATE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ARTICLE; COOLING; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG MIXTURE; FLOW MEASUREMENT; GLASS TRANSITION TEMPERATURE; HOT MELT EXTRUSION; PARALLEL PLATE OSCILLATORY RHEOMETRY; PELLET EXTRUSION; PRIORITY JOURNAL; VISCOSITY;

CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; CITRATES; DELAYED-ACTION PREPARATIONS; LAMIVUDINE; MICROSCOPY, POLARIZATION; PHASE TRANSITION; PLASTICIZERS; POLYETHYLENE GLYCOLS; RHEOLOGY; SOLUBILITY; THERMOGRAVIMETRY; TRANSITION TEMPERATURE; VISCOSITY; ZIDOVUDINE;

EID: 80455122887     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.09.003     Document Type: Article

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