Melt extrusion - An alternative method for enhancing the dissolution rate of 17β-estradiol hemihydrate

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 49, Issue 3, 2000, Pages 237-242

  Hulsmann S ^a,b   Backensfeld, T ^a   Keitel, S ^a   Bodmeier, R ^b  

^a BAYER PHARMA AG   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

17 Estradiol hemihydrate; Melt extrusion; Polymers; Poorly soluble drugs; Solid dispersions; Tablets

Indexed keywords

ESTRADIOL; EXCIPIENT; GELUCIRE; KOLLIDON VA64; MACROGOL 6000; POLY(VINYLPYRROLIDONE CO VINYLACETATE); POVIDONE; SUCROESTER WE15; SUCROSE PALMITATE; UNCLASSIFIED DRUG;

ARTICLE; DISPERSION; DISSOLUTION; DRUG MANUFACTURE; DRUG SOLUBILITY; TABLET; TECHNIQUE; X RAY DIFFRACTION;

DRUG COMPOUNDING; ESTRADIOL; PARTICLE SIZE; SOLUBILITY; SOLUTIONS; SOLVENTS; TABLETS; X-RAY DIFFRACTION;

EID: 0342804284     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(00)00077-1     Document Type: Article

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