Characterization of cellulosic hot-melt extruded films containing lidocaine

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 59, Issue 1, 2005, Pages 189-196

  Repka, Michael A ^a,b   Gutta, Kavitha ^a   Prodduturi, Suneela ^a   Munjal, Manish ^a   Stodghill, Steven P ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Hot melt extrusion; Hydroxypropyl cellulose; Hydroxypropyl methyl cellulose; Lidocaine; Muco adhesive films; Texture analyzer

Indexed keywords

HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; LIDOCAINE; METHYLCELLULOSE; POLYMER;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG SOLUBILITY; FILM; PELLET EXTRUSION; SUSTAINED DRUG RELEASE; THERMAL ANALYSIS; X RAY DIFFRACTION;

CELLULOSE; CHEMISTRY, PHARMACEUTICAL; LACTOSE; LIDOCAINE; METHYLCELLULOSE; OXAZINES;

EID: 9644291420     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2004.06.008     Document Type: Article

References (27)

1. K. Schwach-Abdellaoui, N. Vivien-Castioni, and R. Gurny Local delivery of antimicrobial agents for the treatment of periodontal diseases Eur. J. Pharm. Biopharm. 50 2000 83 99
2. M. Ishida, N. Nambu, and T. Nagai Mucosal dosage form of lidocaine for toothache using hydroxypropyl cellulose and carbopol Chem. Pharm. Bull. 30 1982 980 984
3. M.A. Repka, S. Prodduturi, and S.P. Stodghill Production and characterization of hot-melt extruded films containing clotrimazole Drug Dev. Ind. Pharm. 29 2003 757 765
4. W.G. Powderly, K.H. Mayer, and J.R. Perfect Diagnosis and treatment of oropharyngeal candidiasis in patients infected with hiv: a critical reassessment AIDS Res. Hum. Retroviruses 15 1999 1405 1412
5. R. Khanna, S.P. Agarwal, and A. Ahuja Preparation and evaluation of bioerodible buccal tablets containing clotrimazole Int. J. Pharm. 138 1996 67 73
6. R. Khanna, S.P. Agarwal, and A. Alka Preparation and evaluation of muco-adhesive buccal films of clotrimazole for oral candida infections Indian J. Pharm. Sci. 59 1997 299 305
7. N.A. Peppas, and P.A. Buri Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues J. Control. Rel. 2 1985 257 275
8. S. Senel, G. Ikinci, and S. Kas Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery Int. J. Pharm. 193 2000 197 203
9. P. Sharma, and V. Hamsa Formulation and evaluation of buccal mucoadhesive patches of terbutaline sulphate S.T.P. Pharma Sci. 11 2001 275 281
10. J.C. Gutierrez-Rocca, and J.W. McGinity Influence of aging on the physical-mechanical properties of acrylic resin films cast from aqueous dispersions and organic solutions Drug Dev. Ind. Pharm. 19 1993 315 332
11. C. Aitken-Nichol, F. Zhang, and J.W. McGinity Hot melt extrusion of acrylic films Pharm. Res. 13 1996 804 808
12. K. Groningsson, E. Lindgren, E. Lundberg, and E. Sandberg Lidocaine base and lidocaine hydrochloride in: Analytical Profiles of Drug Substances 1985 Academic Press New York
13. K.K. Peh, and C.F. Wong Polymeric films as vehicle for buccal delivery: swelling, mechanical, and bioadhesive properties J. Pharm. Pharmaceut. Sci. 2 1999 53 61
14. U. S. Food and drug administration, Code of Federal register, vol. 60, No. 230/Thursday, November 30 (1995) 61638-61642.
15. Klucel hydroxy propyl cellulose physical and chemical properties, in: Technical bulletin, aqualon products for the pharmaceutical industry, Willmington, DE, 2000.
16. R. Jalil, and A.J. Ferdous Effect of viscosity increasing agent and electrolyte concentration on the release rate of theophylline from a hpmc based sustained release capsules Drug Dev. Ind. Pharm. 19 1993 2637 2643
17. M.A. Repka, T.G. Gerding, S.L. Repka, and J.W. McGinity Influence of plasticizers and drugs on the physical-mechanical properties of hydroxypropylcellulose films prepared by hot-melt extrusion Drug Dev. Ind. Pharm. 25 1999 625 633
18. C. Ahlneck, and G. Zografi The molecular basis for moisture effects on the physical and chemical stability of drugs in the solid-state Int. J. Pharm. 62 1990 87 95
19. X. Yang, and J.R. Robinson Bioadhesion in mucosal drug delivery T. Okano Biorelated Polymers and Gels: Controlled Release and Applications in Biomedical Engineering 1998 Academic press New York 135 192
20. C.F. Wong, K.H. Yuen, and K.K. Peh An in-vitro method for buccal adhesion studies: importance of instrument variables Int. J. Pharm. 180 1999 47 57
21. A.R. Rennie Crystalline polymers G.M. Swallowe Mechanical Properties and Testing of Polymers 1999 Kluwer Dordrecht, The Netherlands 32 33
22. T.D. Reynold, S.H. Gehrke, A.S. Hussain, and L.S. Shenouda Polymer erosion and drug release characterization of hydroxypropyl methyl cellulose matrices J. Pharm. Sci. 87 1998 1115 1123
23. E.C. Ibezim, C.O. Esimone, and M.U. Adikwu The release properties of microcapsules prepared with polymerized latex of landolphia dulcis Acta Pharm. 48 1998 111 118
24. J.B. Schwartz, A.P. Simunelli, and W.I. Higuchi Drug release from wax matrices i analysis of data with first-order kinetics and with the diffusion-controlled model J. Pharm. Sci. 57 1968 274 277
25. J.E. Mockel, and C. Lippold Zero-order drug release from hydrocolloid matrices Pharm. Res. 10 1993 1066 1070
26. N. Shah, G.-H. Zhang, and A.W. Malick Prediction of drug release from hydroxypropyl methylcellulose (hpmc) matrices: effect of polymer concentration Pharm. Res. 10 1993 1693 1695
27. W.D. Lindner, J.E. Mockel, and B.C. Lippold Controlled release of drugs from hydrocolloid embeddings Pharmazie 51 1996 263 272