-
2
-
-
80054120815
-
A thematic review series: Lipid droplet storage and metabolism: From yeast to man
-
K. Reue A thematic review series: lipid droplet storage and metabolism: from yeast to man J Lipid Res 52 2011 1865 1868
-
(2011)
J Lipid Res
, vol.52
, pp. 1865-1868
-
-
Reue, K.1
-
3
-
-
84862668222
-
The dynamic roles of intracellular lipid droplets: From archaea to mammals
-
D.J. Murphy The dynamic roles of intracellular lipid droplets: from archaea to mammals Protoplasma 249 2012 541 585
-
(2012)
Protoplasma
, vol.249
, pp. 541-585
-
-
Murphy, D.J.1
-
4
-
-
38849096602
-
Imaging of lipid biosynthesis: How a neutral lipid enters lipid droplets
-
DOI 10.1111/j.1600-0854.2007.00689.x
-
L. Kuerschner, C. Moessinger, and C. Thiele Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets Traffic 9 2008 338 352 (Pubitemid 351188994)
-
(2008)
Traffic
, vol.9
, Issue.3
, pp. 338-352
-
-
Kuerschner, L.1
Moessinger, C.2
Thiele, C.3
-
5
-
-
78650825607
-
Quantitative analysis of lipid droplet fusion: Inefficient steady state fusion but rapid stimulation by chemical fusogens
-
S. Murphy, S. Martin, and R.G. Parton Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens PLoS One 5 2010 e15030
-
(2010)
PLoS One
, vol.5
, pp. 15030
-
-
Murphy, S.1
Martin, S.2
Parton, R.G.3
-
6
-
-
84861913952
-
Lipid droplets and cellular lipid metabolism
-
T.C. Walther, and R.V. Farese Jr. Lipid droplets and cellular lipid metabolism Annu Rev Biochem 81 2012 687 714
-
(2012)
Annu Rev Biochem
, vol.81
, pp. 687-714
-
-
Walther, T.C.1
Farese, Jr.R.V.2
-
7
-
-
85027952816
-
Role of lipid droplet proteins in liver steatosis
-
T. Okumura Role of lipid droplet proteins in liver steatosis J Physiol Biochem 67 2011 629 636
-
(2011)
J Physiol Biochem
, vol.67
, pp. 629-636
-
-
Okumura, T.1
-
8
-
-
46249097997
-
Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis
-
DOI 10.1002/hep.22268
-
B.K. Straub, P. Stoeffel, H. Heid, R. Zimbelmann, and P. Schirmacher Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis Hepatology 47 2008 1936 1946 (Pubitemid 351945561)
-
(2008)
Hepatology
, vol.47
, Issue.6
, pp. 1936-1946
-
-
Straub, B.K.1
Stoeffel, P.2
Heid, H.3
Zimbelmann, R.4
Schirmacher, P.5
-
9
-
-
44449095056
-
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization
-
DOI 10.1038/nature06928, PII NATURE06928
-
Y. Guo, T.C. Walther, M. Rao, N. Stuurman, G. Goshima, and K. Terayama et al. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization Nature 453 2008 657 661 (Pubitemid 351769298)
-
(2008)
Nature
, vol.453
, Issue.7195
, pp. 657-661
-
-
Guo, Y.1
Walther, T.C.2
Rao, M.3
Stuurman, N.4
Goshima, G.5
Terayama, K.6
Wong, J.S.7
Vale, R.D.8
Walter, P.9
Farese Jr., R.V.10
-
10
-
-
33745756902
-
Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein
-
DOI 10.1093/jb/mvj104
-
S. Sato, M. Fukasawa, Y. Yamakawa, T. Natsume, T. Suzuki, and I. Shoji et al. Proteomic profiling of lipid droplet proteins in hepatoma cell lines expressing hepatitis C virus core protein J Biochem 139 2006 921 930 (Pubitemid 44014586)
-
(2006)
Journal of Biochemistry
, vol.139
, Issue.5
, pp. 921-930
-
-
Sato, S.1
Fukasawa, M.2
Yamakawa, Y.3
Natsume, T.4
Suzuki, T.5
Shoji, I.6
Aizaki, H.7
Miyamura, T.8
Nishijima, M.9
-
11
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
DOI 10.1172/JCI200422422
-
J.D. Browning, and J.D. Horton Molecular mediators of hepatic steatosis and liver injury J Clin Invest 114 2004 147 152 (Pubitemid 39071617)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.2
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
12
-
-
84863012179
-
Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation
-
J.S. Lee, R. Mendez, H.H. Heng, Z.Q. Yang, and K. Zhang Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation Am J Transl Res 4 2012 102 113
-
(2012)
Am J Transl Res
, vol.4
, pp. 102-113
-
-
Lee, J.S.1
Mendez, R.2
Heng, H.H.3
Yang, Z.Q.4
Zhang, K.5
-
13
-
-
79957943690
-
Molecular mechanisms of steatosis in nonalcoholic fatty liver disease
-
P. Pettinelli, A.M. Obregon, and L.A. Videla Molecular mechanisms of steatosis in nonalcoholic fatty liver disease Nutr Hosp 26 2011 441 450
-
(2011)
Nutr Hosp
, vol.26
, pp. 441-450
-
-
Pettinelli, P.1
Obregon, A.M.2
Videla, L.A.3
-
14
-
-
84863356961
-
Endoplasmic reticulum stress-associated lipid droplet formation and type II diabetes
-
X. Zhang, and K. Zhang Endoplasmic reticulum stress-associated lipid droplet formation and type II diabetes Biochem Res Int 2012 2012 247275
-
(2012)
Biochem Res Int
, vol.2012
, pp. 247275
-
-
Zhang, X.1
Zhang, K.2
-
15
-
-
84877039529
-
Nonalcoholic fatty liver disease: Current issues and novel treatment approaches
-
R. Lomonaco, N.E. Sunny, F. Bril, and K. Cusi Nonalcoholic fatty liver disease: current issues and novel treatment approaches Drugs 73 2013 1 14
-
(2013)
Drugs
, vol.73
, pp. 1-14
-
-
Lomonaco, R.1
Sunny, N.E.2
Bril, F.3
Cusi, K.4
-
16
-
-
81855213130
-
Nonalcoholic steatohepatitis: The therapeutic challenge of a global epidemic
-
J.M. Schattenberg, and D. Schuppan Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic Curr Opin Lipidol 22 2011 479 488
-
(2011)
Curr Opin Lipidol
, vol.22
, pp. 479-488
-
-
Schattenberg, J.M.1
Schuppan, D.2
-
17
-
-
54049150442
-
Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis
-
N. Anderson, and J. Borlak Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis Pharmacol Rev 60 2008 311 357
-
(2008)
Pharmacol Rev
, vol.60
, pp. 311-357
-
-
Anderson, N.1
Borlak, J.2
-
18
-
-
34249711303
-
Metabolic Syndrome and NASH
-
DOI 10.1016/j.cld.2007.02.013, PII S108932610700013X, Non-Alcoholic Steatohepatitis and Non-Alcoholic Fatty Liver Disease
-
G. Marchesini, and R. Marzocchi Metabolic syndrome and NASH Clin Liver Dis 11 2007 105 117 ix (Pubitemid 46829976)
-
(2007)
Clinics in Liver Disease
, vol.11
, Issue.1
, pp. 105-117
-
-
Marchesini, G.1
Marzocchi, R.2
-
19
-
-
80051495481
-
Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes
-
S. Mitsutake, K. Zama, H. Yokota, T. Yoshida, M. Tanaka, and M. Mitsui et al. Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes J Biol Chem 286 2011 28544 28555
-
(2011)
J Biol Chem
, vol.286
, pp. 28544-28555
-
-
Mitsutake, S.1
Zama, K.2
Yokota, H.3
Yoshida, T.4
Tanaka, M.5
Mitsui, M.6
-
20
-
-
33244493738
-
f 60-400 particle composition reduces uptake of LDL by HepG2 cells
-
DOI 10.1194/jlr.M500382-JLR200
-
K.G. Jackson, V. Maitin, D.S. Leake, P. Yaqoob, and C.M. Williams Saturated fat-induced changes in Sf 60-400 particle composition reduces uptake of LDL by HepG2 cells J Lipid Res 47 2006 393 403 (Pubitemid 43276925)
-
(2006)
Journal of Lipid Research
, vol.47
, Issue.2
, pp. 393-403
-
-
Jackson, K.G.1
Maitin, V.2
Leake, D.S.3
Yaqoob, P.4
Williams, C.M.5
-
21
-
-
0034003980
-
The role of the LDL receptor in apolipoprotein B secretion
-
J. Twisk, D.L. Gillian-Daniel, A. Tebon, L. Wang, P.H. Barrett, and A.D. Attie The role of the LDL receptor in apolipoprotein B secretion J Clin Invest 105 2000 521 532
-
(2000)
J Clin Invest
, vol.105
, pp. 521-532
-
-
Twisk, J.1
Gillian-Daniel, D.L.2
Tebon, A.3
Wang, L.4
Barrett, P.H.5
Attie, A.D.6
-
22
-
-
50849085763
-
Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase
-
J.R. Simard, B.K. Pillai, and J.A. Hamilton Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase Biochemistry 47 2008 9081 9089
-
(2008)
Biochemistry
, vol.47
, pp. 9081-9089
-
-
Simard, J.R.1
Pillai, B.K.2
Hamilton, J.A.3
-
23
-
-
0037832573
-
Fast flip-flop of cholesterol and fatty acids in membranes: Implications for membrane transport proteins
-
DOI 10.1097/00041433-200306000-00006
-
J.A. Hamilton Fast flip-flop of cholesterol and fatty acids in membranes: implications for membrane transport proteins Curr Opin Lipidol 14 2003 263 271 (Pubitemid 36688205)
-
(2003)
Current Opinion in Lipidology
, vol.14
, Issue.3
, pp. 263-271
-
-
Hamilton, J.A.1
-
24
-
-
38449087713
-
ChREBP, a transcriptional regulator of glucose and lipid metabolism
-
DOI 10.1146/annurev.nutr.27.061406.093618
-
C. Postic, R. Dentin, P.D. Denechaud, and J. Girard ChREBP, a transcriptional regulator of glucose and lipid metabolism Annu Rev Nutr 27 2007 179 192 (Pubitemid 351373354)
-
(2007)
Annual Review of Nutrition
, vol.27
, pp. 179-192
-
-
Postic, C.1
Dentin, R.2
Denechaud, P.-D.3
Girard, J.4
-
25
-
-
80054745073
-
Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells
-
J. Krammer, M. Digel, F. Ehehalt, W. Stremmel, J. Fullekrug, and R. Ehehalt Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells Int J Med Sci 8 2011 599 614
-
(2011)
Int J Med Sci
, vol.8
, pp. 599-614
-
-
Krammer, J.1
Digel, M.2
Ehehalt, F.3
Stremmel, W.4
Fullekrug, J.5
Ehehalt, R.6
-
26
-
-
84860311914
-
The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake
-
M. Poppelreuther, B. Rudolph, C. Du, R. Grossmann, M. Becker, and C. Thiele et al. The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake J Lipid Res 53 2012 888 900
-
(2012)
J Lipid Res
, vol.53
, pp. 888-900
-
-
Poppelreuther, M.1
Rudolph, B.2
Du, C.3
Grossmann, R.4
Becker, M.5
Thiele, C.6
-
27
-
-
79952211574
-
Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation
-
J.M. Orellana-Gavalda, L. Herrero, M.I. Malandrino, A. Paneda, M. Sol Rodriguez-Pena, and H. Petry et al. Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation Hepatology 53 2011 821 832
-
(2011)
Hepatology
, vol.53
, pp. 821-832
-
-
Orellana-Gavalda, J.M.1
Herrero, L.2
Malandrino, M.I.3
Paneda, A.4
Sol Rodriguez-Pena, M.5
Petry, H.6
-
28
-
-
65449159320
-
Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice
-
Q. Wang, L. Jiang, J. Wang, S. Li, Y. Yu, and J. You et al. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice Hepatology 49 2009 1166 1175
-
(2009)
Hepatology
, vol.49
, pp. 1166-1175
-
-
Wang, Q.1
Jiang, L.2
Wang, J.3
Li, S.4
Yu, Y.5
You, J.6
-
29
-
-
65549136260
-
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: Role of stearoyl-CoA desaturase
-
Z.Z. Li, M. Berk, T.M. McIntyre, and A.E. Feldstein Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase J Biol Chem 284 2009 5637 5644
-
(2009)
J Biol Chem
, vol.284
, pp. 5637-5644
-
-
Li, Z.Z.1
Berk, M.2
McIntyre, T.M.3
Feldstein, A.E.4
-
30
-
-
34250827848
-
ELOVL2 overexpression enhances triacylglycerol synthesis in 3T3-L1 and F442A cells
-
DOI 10.1016/j.febslet.2007.05.081, PII S0014579307006436
-
T. Kobayashi, D. Zadravec, and A. Jacobsson ELOVL2 overexpression enhances triacylglycerol synthesis in 3T3-L1 and F442A cells FEBS Lett 581 2007 3157 3163 (Pubitemid 46977355)
-
(2007)
FEBS Letters
, vol.581
, Issue.17
, pp. 3157-3163
-
-
Kobayashi, T.1
Zadravec, D.2
Jacobsson, A.3
-
31
-
-
78649818490
-
Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity
-
D. Zadravec, A. Brolinson, R.M. Fisher, C. Carneheim, R.I. Csikasz, and J. Bertrand-Michel et al. Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity FASEB J 24 2010 4366 4377
-
(2010)
FASEB J
, vol.24
, pp. 4366-4377
-
-
Zadravec, D.1
Brolinson, A.2
Fisher, R.M.3
Carneheim, C.4
Csikasz, R.I.5
Bertrand-Michel, J.6
-
32
-
-
77953515738
-
Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species
-
C.D. Green, C.G. Ozguden-Akkoc, Y. Wang, D.B. Jump, and L.K. Olson Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species J Lipid Res 51 2010 1871 1877
-
(2010)
J Lipid Res
, vol.51
, pp. 1871-1877
-
-
Green, C.D.1
Ozguden-Akkoc, C.G.2
Wang, Y.3
Jump, D.B.4
Olson, L.K.5
-
33
-
-
64149083800
-
Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice
-
Y.A. Moon, R.E. Hammer, and J.D. Horton Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice J Lipid Res 50 2009 412 423
-
(2009)
J Lipid Res
, vol.50
, pp. 412-423
-
-
Moon, Y.A.1
Hammer, R.E.2
Horton, J.D.3
-
34
-
-
77950612089
-
A subset of dysregulated metabolic and survival genes is associated with severity of hepatic steatosis in obese Zucker rats
-
X. Buque, M.J. Martinez, A. Cano, M.E. Miquilena-Colina, C. Garcia-Monzon, and P. Aspichueta et al. A subset of dysregulated metabolic and survival genes is associated with severity of hepatic steatosis in obese Zucker rats J Lipid Res 51 2010 500 513
-
(2010)
J Lipid Res
, vol.51
, pp. 500-513
-
-
Buque, X.1
Martinez, M.J.2
Cano, A.3
Miquilena-Colina, M.E.4
Garcia-Monzon, C.5
Aspichueta, P.6
-
35
-
-
42949091932
-
Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus-infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune function-associated networks
-
DOI 10.1128/IAI.01044-07
-
A. Garcia, M.M. Ihrig, R.C. Fry, Y. Feng, S. Xu, and S.R. Boutin et al. Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus-infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune function-associated networks Infect Immun 76 2008 1866 1876 (Pubitemid 351656120)
-
(2008)
Infection and Immunity
, vol.76
, Issue.5
, pp. 1866-1876
-
-
Garcia, A.1
Ihrig, M.M.2
Fry, R.C.3
Feng, Y.4
Xu, S.5
Boutin, S.R.6
Rogers, A.B.7
Muthupalani, S.8
Samson, L.D.9
Fox, J.G.10
-
36
-
-
84875671236
-
Inhibitors of fatty acid synthesis induce PPAR alpha-regulated fatty acid beta-oxidative genes: Synergistic roles of L-FABP and glucose
-
H. Huang, A.L. McIntosh, G.G. Martin, A.D. Petrescu, K.K. Landrock, and D. Landrock et al. Inhibitors of fatty acid synthesis induce PPAR alpha-regulated fatty acid beta-oxidative genes: synergistic roles of L-FABP and glucose PPAR Res 2013 2013 865604
-
(2013)
PPAR Res
, vol.2013
, pp. 865604
-
-
Huang, H.1
McIntosh, A.L.2
Martin, G.G.3
Petrescu, A.D.4
Landrock, K.K.5
Landrock, D.6
-
37
-
-
84871023781
-
Liver X receptors and fat cell metabolism
-
J. Laurencikiene, and M. Ryden Liver X receptors and fat cell metabolism Int J Obes Lond 36 2012 1494 1502
-
(2012)
Int J Obes Lond
, vol.36
, pp. 1494-1502
-
-
Laurencikiene, J.1
Ryden, M.2
-
38
-
-
84866149370
-
Update on ppargamma and nonalcoholic fatty liver disease
-
G.P. Ables Update on ppargamma and nonalcoholic fatty liver disease PPAR Res 2012 2012 912351
-
(2012)
PPAR Res
, vol.2012
, pp. 912351
-
-
Ables, G.P.1
-
40
-
-
84869215008
-
FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth
-
X. Du, Q.R. Wang, E. Chan, M. Merchant, J. Liu, and D. French et al. FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth Cancer Res 72 2012 5843 5855
-
(2012)
Cancer Res
, vol.72
, pp. 5843-5855
-
-
Du, X.1
Wang, Q.R.2
Chan, E.3
Merchant, M.4
Liu, J.5
French, D.6
-
41
-
-
84861425644
-
The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2
-
J. Qi, W. Lang, J.G. Geisler, P. Wang, I. Petrounia, and S. Mai et al. The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 J Lipid Res 53 2012 1106 1116
-
(2012)
J Lipid Res
, vol.53
, pp. 1106-1116
-
-
Qi, J.1
Lang, W.2
Geisler, J.G.3
Wang, P.4
Petrounia, I.5
Mai, S.6
-
42
-
-
84875164496
-
Hepatic triacylglycerol synthesis and secretion: DGAT2 as the link between glycaemia and triglyceridaemia
-
V.A. Zammit Hepatic triacylglycerol synthesis and secretion: DGAT2 as the link between glycaemia and triglyceridaemia Biochem J 451 2013 1 12
-
(2013)
Biochem J
, vol.451
, pp. 1-12
-
-
Zammit, V.A.1
-
44
-
-
84865227832
-
Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides and de novo synthesized fatty acids in HepG2 cells
-
H.R. Wurie, L. Buckett, and V.A. Zammit Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides and de novo synthesized fatty acids in HepG2 cells FEBS J 279 2012 3033 3047
-
(2012)
FEBS J
, vol.279
, pp. 3033-3047
-
-
Wurie, H.R.1
Buckett, L.2
Zammit, V.A.3
-
45
-
-
84856072854
-
Packaging of fat: An evolving model of lipid droplet assembly and expansion
-
D.L. Brasaemle, and N.E. Wolins Packaging of fat: an evolving model of lipid droplet assembly and expansion J Biol Chem 287 2012 2273 2279
-
(2012)
J Biol Chem
, vol.287
, pp. 2273-2279
-
-
Brasaemle, D.L.1
Wolins, N.E.2
-
46
-
-
7244242391
-
Overexpression of human diacylglycerol acyltransferase 1, acyl-CoA:Cholesterol acyltransferase 1, or acyl-CoA:Cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells
-
DOI 10.1074/jbc.M408507200
-
J.J. Liang, P. Oelkers, C. Guo, P.C. Chu, J.L. Dixon, and H.N. Ginsberg et al. Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells J Biol Chem 279 2004 44938 44944 (Pubitemid 39430907)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.43
, pp. 44938-44944
-
-
Liang, J.J.1
Oelkers, P.2
Guo, C.3
Chu, P.-C.4
Dixon, J.L.5
Ginsberg, H.N.6
Sturley, S.L.7
-
47
-
-
0034623070
-
Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine
-
C.C. Chang, N. Sakashita, K. Ornvold, O. Lee, E.T. Chang, and R. Dong et al. Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine J Biol Chem 275 2000 28083 28092
-
(2000)
J Biol Chem
, vol.275
, pp. 28083-28092
-
-
Chang, C.C.1
Sakashita, N.2
Ornvold, K.3
Lee, O.4
Chang, E.T.5
Dong, R.6
-
48
-
-
0031847230
-
Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines
-
O. Lee, C.C. Chang, W. Lee, and T.Y. Chang Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines J Lipid Res 39 1998 1722 1727 (Pubitemid 28377938)
-
(1998)
Journal of Lipid Research
, vol.39
, Issue.8
, pp. 1722-1727
-
-
Lee, O.1
Chang, C.C.Y.2
Lee, W.3
Chang, T.-Y.4
-
49
-
-
0034520194
-
Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates
-
R.G. Lee, M.C. Willingham, M.A. Davis, K.A. Skinner, and L.L. Rudel Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates J Lipid Res 41 2000 1991 2001 (Pubitemid 32038994)
-
(2000)
Journal of Lipid Research
, vol.41
, Issue.12
, pp. 1991-2001
-
-
Lee, R.G.1
Willingham, M.C.2
Davis, M.A.3
Skinner, K.A.4
Rudel, L.L.5
-
50
-
-
20844451381
-
ACAT2 is localized to hepatocytes and is the major cholesterol- esterifying enzyme in human liver
-
DOI 10.1161/01.CIR.0000143163.76212.0B
-
P. Parini, M. Davis, A.T. Lada, S.K. Erickson, T.L. Wright, and U. Gustafsson et al. ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver Circulation 110 2004 2017 2023 (Pubitemid 39331916)
-
(2004)
Circulation
, vol.110
, Issue.14
, pp. 2017-2023
-
-
Parini, P.1
Davis, M.2
Lada, A.T.3
Erickson, S.K.4
Wright, T.L.5
Gustafsson, U.6
Sahlin, S.7
Einarsson, C.8
Eriksson, M.9
Angelin, B.10
Tomoda, H.11
Omura, S.12
Willingham, M.C.13
Rudel, L.L.14
-
51
-
-
0035081589
-
Acyl coenzyme A: Cholesterol acyltransferase types 1 and 2: Structure and function in atherosclerosis
-
DOI 10.1097/00041433-200104000-00005
-
L.L. Rudel, R.G. Lee, and T.L. Cockman Acyl coenzyme A:cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis Curr Opin Lipidol 12 2001 121 127 (Pubitemid 32242919)
-
(2001)
Current Opinion in Lipidology
, vol.12
, Issue.2
, pp. 121-127
-
-
Rudel, L.L.1
Lee, R.G.2
Cockman, T.L.3
-
52
-
-
84897017252
-
-
The AOCS Lipid Library [Internet]; July [cited 19.11.2013]
-
Fillimore N, Alrob OA, Lopaschuk GD. Fatty acid β oxidation. The AOCS Lipid Library [Internet]; July 2011. < http://lipidlibrary.aocs.org/ animbio/faoxid/index.htm > [cited 19.11.2013].
-
(2011)
Fatty Acid β Oxidation
-
-
Fillimore, N.1
Alrob, O.A.2
Lopaschuk, G.D.3
-
53
-
-
79958841953
-
FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation
-
B.K. Smith, S.S. Jain, S. Rimbaud, A. Dam, J. Quadrilatero, and R. Ventura-Clapier et al. FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation Biochem J 437 2011 125 134
-
(2011)
Biochem J
, vol.437
, pp. 125-134
-
-
Smith, B.K.1
Jain, S.S.2
Rimbaud, S.3
Dam, A.4
Quadrilatero, J.5
Ventura-Clapier, R.6
-
56
-
-
77954363354
-
Apoptosis is associated with CD36/fatty acid translocase upregulation in non-alcoholic steatohepatitis
-
L.P. Bechmann, R.K. Gieseler, J.P. Sowa, A. Kahraman, J. Erhard, and I. Wedemeyer et al. Apoptosis is associated with CD36/fatty acid translocase upregulation in non-alcoholic steatohepatitis Liver Int 30 2010 850 859
-
(2010)
Liver Int
, vol.30
, pp. 850-859
-
-
Bechmann, L.P.1
Gieseler, R.K.2
Sowa, J.P.3
Kahraman, A.4
Erhard, J.5
Wedemeyer, I.6
-
57
-
-
84885993664
-
CD36 deletion reduces VLDL secretion, modulates liver prostaglandin levels and exacerbates hepatic steatosis in ob/ob mice
-
F. Nassir, O.L. Adewole, E.M. Brunt, and N.A. Abumrad CD36 deletion reduces VLDL secretion, modulates liver prostaglandin levels and exacerbates hepatic steatosis in ob/ob mice J Lipid Res 2013
-
(2013)
J Lipid Res
-
-
Nassir, F.1
Adewole, O.L.2
Brunt, E.M.3
Abumrad, N.A.4
-
58
-
-
80052596785
-
Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C
-
M.E. Miquilena-Colina, E. Lima-Cabello, S. Sanchez-Campos, M.V. Garcia-Mediavilla, M. Fernandez-Bermejo, and T. Lozano-Rodriguez et al. Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C Gut 60 2011 1394 1402
-
(2011)
Gut
, vol.60
, pp. 1394-1402
-
-
Miquilena-Colina, M.E.1
Lima-Cabello, E.2
Sanchez-Campos, S.3
Garcia-Mediavilla, M.V.4
Fernandez-Bermejo, M.5
Lozano-Rodriguez, T.6
-
59
-
-
33845593356
-
100/100 mice fed trans-10,cis-12 conjugated linoleic acid
-
DOI 10.1194/jlr.M600140-JLR200
-
P. Degrace, B. Moindrot, I. Mohamed, J. Gresti, Z.Y. Du, and J.M. Chardigny et al. Upregulation of liver VLDL receptor and FAT/CD36 expression in LDLR-/- apoB100/100 mice fed trans-10, cis-12 conjugated linoleic acid J Lipid Res 47 2006 2647 2655 (Pubitemid 44936078)
-
(2006)
Journal of Lipid Research
, vol.47
, Issue.12
, pp. 2647-2655
-
-
Degrace, P.1
Moindrot, B.2
Mohamed, I.3
Gresti, J.4
Du, Z.-Y.5
Chardigny, J.-M.6
Sebedio, J.-L.7
Clouet, P.8
-
60
-
-
36849037401
-
Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity
-
DOI 10.2337/db07-0907
-
D.P. Koonen, R.L. Jacobs, M. Febbraio, M.E. Young, C.L. Soltys, and H. Ong et al. Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity Diabetes 56 2007 2863 2871 (Pubitemid 350223619)
-
(2007)
Diabetes
, vol.56
, Issue.12
, pp. 2863-2871
-
-
Koonen, D.P.Y.1
Jacobs, R.L.2
Febbraio, M.3
Young, M.E.4
Soltys, C.-L.M.5
Ong, H.6
Vance, D.E.7
Dyck, J.R.B.8
-
61
-
-
0036109168
-
Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice
-
DOI 10.1172/JCI200214596
-
T. Hajri, X.X. Han, A. Bonen, and N.A. Abumrad Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice J Clin Invest 109 2002 1381 1389 (Pubitemid 34546903)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.10
, pp. 1381-1389
-
-
Hajri, T.1
Han, X.X.2
Bonen, A.3
Abumrad, N.A.4
-
62
-
-
74949084316
-
Membrane fatty acid transporters as regulators of lipid metabolism: Implications for metabolic disease
-
J.F. Glatz, J.J. Luiken, and A. Bonen Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease Physiol Rev 90 2010 367 417
-
(2010)
Physiol Rev
, vol.90
, pp. 367-417
-
-
Glatz, J.F.1
Luiken, J.J.2
Bonen, A.3
-
63
-
-
12744274513
-
Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion
-
H. Noushmehr, E. D'Amico, L. Farilla, H. Hui, K.A. Wawrowsky, and W. Mlynarski et al. Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion Diabetes 54 2005 472 481
-
(2005)
Diabetes
, vol.54
, pp. 472-481
-
-
Noushmehr, H.1
D'Amico, E.2
Farilla, L.3
Hui, H.4
Wawrowsky, K.A.5
Mlynarski, W.6
-
64
-
-
0031957128
-
Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL
-
D. Calvo, D. Gomez-Coronado, Y. Suarez, M.A. Lasuncion, and M.A. Vega Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL J Lipid Res 39 1998 777 788 (Pubitemid 28163280)
-
(1998)
Journal of Lipid Research
, vol.39
, Issue.4
, pp. 777-788
-
-
Calvo, D.1
Gomez-Coronado, D.2
Suarez, Y.3
Lasuncion, M.A.4
Vega, M.A.5
-
65
-
-
38649096259
-
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis
-
J. Zhou, M. Febbraio, T. Wada, Y. Zhai, R. Kuruba, and J. He et al. Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis Gastroenterology 134 2008 556 567
-
(2008)
Gastroenterology
, vol.134
, pp. 556-567
-
-
Zhou, J.1
Febbraio, M.2
Wada, T.3
Zhai, Y.4
Kuruba, R.5
He, J.6
-
66
-
-
77958196146
-
Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport
-
Y. Kawano, S. Nishiumi, S. Tanaka, K. Nobutani, A. Miki, and Y. Yano et al. Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport Arch Biochem Biophys 504 2010 221 227
-
(2010)
Arch Biochem Biophys
, vol.504
, pp. 221-227
-
-
Kawano, Y.1
Nishiumi, S.2
Tanaka, S.3
Nobutani, K.4
Miki, A.5
Yano, Y.6
-
67
-
-
77955488532
-
A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis
-
J.H. Lee, T. Wada, M. Febbraio, J. He, T. Matsubara, and M.J. Lee et al. A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis Gastroenterology 139 2010 653 663
-
(2010)
Gastroenterology
, vol.139
, pp. 653-663
-
-
Lee, J.H.1
Wada, T.2
Febbraio, M.3
He, J.4
Matsubara, T.5
Lee, M.J.6
-
68
-
-
75149115740
-
The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
-
Y. Fan, G.P. Boivin, E.S. Knudsen, D.W. Nebert, Y. Xia, and A. Puga The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis Cancer Res 70 2010 212 220
-
(2010)
Cancer Res
, vol.70
, pp. 212-220
-
-
Fan, Y.1
Boivin, G.P.2
Knudsen, E.S.3
Nebert, D.W.4
Xia, Y.5
Puga, A.6
-
69
-
-
84880570433
-
Liver fatty acid binding protein gene-ablation exacerbates weight gain in high-fat fed female mice
-
A.L. McIntosh, B.P. Atshaves, D. Landrock, K.K. Landrock, G.G. Martin, and S.M. Storey et al. Liver fatty acid binding protein gene-ablation exacerbates weight gain in high-fat fed female mice Lipids 48 2013 435 448
-
(2013)
Lipids
, vol.48
, pp. 435-448
-
-
McIntosh, A.L.1
Atshaves, B.P.2
Landrock, D.3
Landrock, K.K.4
Martin, G.G.5
Storey, S.M.6
-
70
-
-
84882606619
-
Interactions between human liver fatty acid binding protein and peroxisome proliferator activated receptor selective drugs
-
T. Velkov Interactions between human liver fatty acid binding protein and peroxisome proliferator activated receptor selective drugs PPAR Res 2013 2013 938401
-
(2013)
PPAR Res
, vol.2013
, pp. 938401
-
-
Velkov, T.1
-
71
-
-
66349121402
-
Structural and functional analysis of fatty acid-binding proteins
-
J. Storch, and L. McDermott Structural and functional analysis of fatty acid-binding proteins J Lipid Res 50 Suppl 2009 S126 S131
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Storch, J.1
McDermott, L.2
-
72
-
-
69449106150
-
L-FABP directly interacts with PPARalpha in cultured primary hepatocytes
-
H.A. Hostetler, A.L. McIntosh, B.P. Atshaves, S.M. Storey, H.R. Payne, and A.B. Kier et al. L-FABP directly interacts with PPARalpha in cultured primary hepatocytes J Lipid Res 50 2009 1663 1675
-
(2009)
J Lipid Res
, vol.50
, pp. 1663-1675
-
-
Hostetler, H.A.1
McIntosh, A.L.2
Atshaves, B.P.3
Storey, S.M.4
Payne, H.R.5
Kier, A.B.6
-
73
-
-
48749109440
-
Activation of PPARgamma reverses a defect of surfactant synthesis in mice lacking two types of fatty acid binding protein
-
C. Schachtrup, S. Malcharek, J.J. Haitsma, B. Lachmann, Y. Owada, and B. Binas et al. Activation of PPARgamma reverses a defect of surfactant synthesis in mice lacking two types of fatty acid binding protein Biochim Biophys Acta 1781 2008 314 320
-
(2008)
Biochim Biophys Acta
, vol.1781
, pp. 314-320
-
-
Schachtrup, C.1
Malcharek, S.2
Haitsma, J.J.3
Lachmann, B.4
Owada, Y.5
Binas, B.6
-
74
-
-
84873700660
-
The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARalpha; And repressed by C/EBPalpha: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease
-
C. Guzman, M. Benet, S. Pisonero-Vaquero, M. Moya, M.V. Garcia-Mediavilla, and M.L. Martinez-Chantar et al. The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARalpha; and repressed by C/EBPalpha: implications in FABP1 down-regulation in nonalcoholic fatty liver disease Biochim Biophys Acta 1831 2013 803 818
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 803-818
-
-
Guzman, C.1
Benet, M.2
Pisonero-Vaquero, S.3
Moya, M.4
Garcia-Mediavilla, M.V.5
Martinez-Chantar, M.L.6
-
75
-
-
77955905600
-
Intestinal-FABP and liver-FABP: Novel markers for severe abdominal injury
-
B. Relja, M. Szermutzky, D. Henrich, M. Maier, J.J. de Haan, and T. Lubbers et al. Intestinal-FABP and liver-FABP: novel markers for severe abdominal injury Acad Emerg Med 17 2010 729 735
-
(2010)
Acad Emerg Med
, vol.17
, pp. 729-735
-
-
Relja, B.1
Szermutzky, M.2
Henrich, D.3
Maier, M.4
De Haan, J.J.5
Lubbers, T.6
-
76
-
-
34248337907
-
Fatty acid transport proteins
-
DOI 10.1097/MOL.0b013e3281338558, PII 0004143320070600000008
-
R.E. Gimeno Fatty acid transport proteins Curr Opin Lipidol 18 2007 271 276 (Pubitemid 46743050)
-
(2007)
Current Opinion in Lipidology
, vol.18
, Issue.3
, pp. 271-276
-
-
Gimeno, R.E.1
-
77
-
-
77956803815
-
FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase
-
A. Falcon, H. Doege, A. Fluitt, B. Tsang, N. Watson, and M.A. Kay et al. FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase Am J Physiol Endocrinol Metab 299 2010 E384 E393
-
(2010)
Am J Physiol Endocrinol Metab
, vol.299
-
-
Falcon, A.1
Doege, H.2
Fluitt, A.3
Tsang, B.4
Watson, N.5
Kay, M.A.6
-
78
-
-
0037025401
-
Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling
-
DOI 10.1074/jbc.M203295200
-
S.J. Mihalik, S.J. Steinberg, Z. Pei, J. Park, D.G. Kim, and A.K. Heinzer et al. Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling J Biol Chem 277 2002 24771 24779 (Pubitemid 34952009)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.27
, pp. 24771-24779
-
-
Mihalik, S.J.1
Steinberg, S.J.2
Pei, Z.3
Park, J.4
Kim, D.G.5
Heinzer, A.K.6
Dacremont, G.7
Wanders, R.J.A.8
Cuebas, D.A.9
Smith, K.D.10
Watkins, P.A.11
-
79
-
-
84864365408
-
Specific bile acids inhibit hepatic fatty acid uptake in mice
-
B. Nie, H.M. Park, M. Kazantzis, M. Lin, A. Henkin, and S. Ng et al. Specific bile acids inhibit hepatic fatty acid uptake in mice Hepatology 56 2012 1300 1310
-
(2012)
Hepatology
, vol.56
, pp. 1300-1310
-
-
Nie, B.1
Park, H.M.2
Kazantzis, M.3
Lin, M.4
Henkin, A.5
Ng, S.6
-
80
-
-
84858701950
-
The interaction of hepatic lipid and glucose metabolism in liver diseases
-
L.P. Bechmann, R.A. Hannivoort, G. Gerken, G.S. Hotamisligil, M. Trauner, and A. Canbay The interaction of hepatic lipid and glucose metabolism in liver diseases J Hepatol 56 2012 952 964
-
(2012)
J Hepatol
, vol.56
, pp. 952-964
-
-
Bechmann, L.P.1
Hannivoort, R.A.2
Gerken, G.3
Hotamisligil, G.S.4
Trauner, M.5
Canbay, A.6
-
81
-
-
77956820329
-
SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells
-
T.Q. Truong, D. Aubin, L. Falstrault, M.R. Brodeur, and L. Brissette SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells Cell Biochem Funct 28 2010 480 489
-
(2010)
Cell Biochem Funct
, vol.28
, pp. 480-489
-
-
Truong, T.Q.1
Aubin, D.2
Falstrault, L.3
Brodeur, M.R.4
Brissette, L.5
-
82
-
-
84859786953
-
Caveolins and caveolae, roles in insulin signalling and diabetes
-
P. Stralfors Caveolins and caveolae, roles in insulin signalling and diabetes Adv Exp Med Biol 729 2012 111 126
-
(2012)
Adv Exp Med Biol
, vol.729
, pp. 111-126
-
-
Stralfors, P.1
-
83
-
-
79955599893
-
Altered distribution of caveolin-1 in early liver steatosis
-
M. Mastrodonato, G. Calamita, R. Rossi, D. Mentino, L. Bonfrate, and P. Portincasa et al. Altered distribution of caveolin-1 in early liver steatosis Eur J Clin Invest 41 2011 642 651
-
(2011)
Eur J Clin Invest
, vol.41
, pp. 642-651
-
-
Mastrodonato, M.1
Calamita, G.2
Rossi, R.3
Mentino, D.4
Bonfrate, L.5
Portincasa, P.6
-
84
-
-
0036737860
-
Uptake of long-chain fatty acids in HepG2 cells involves caveolae: Analysis of a novel pathway
-
J. Pohl, A. Ring, and W. Stremmel Uptake of long-chain fatty acids in HepG2 cells involves caveolae: analysis of a novel pathway J Lipid Res 43 2002 1390 1399
-
(2002)
J Lipid Res
, vol.43
, pp. 1390-1399
-
-
Pohl, J.1
Ring, A.2
Stremmel, W.3
-
85
-
-
84858072223
-
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression
-
K.D. Corbin, and S.H. Zeisel Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression Curr Opin Gastroenterol 28 2012 159 165
-
(2012)
Curr Opin Gastroenterol
, vol.28
, pp. 159-165
-
-
Corbin, K.D.1
Zeisel, S.H.2
-
86
-
-
33747079056
-
A choline-deficient diet exacerbates fatty liver but attenuates insulin resistance and glucose intolerance in mice fed a high-fat diet
-
DOI 10.2337/db06-0097
-
P.J. Raubenheimer, M.J. Nyirenda, and B.R. Walker A choline-deficient diet exacerbates fatty liver but attenuates insulin resistance and glucose intolerance in mice fed a high-fat diet Diabetes 55 2006 2015 2020 (Pubitemid 44509974)
-
(2006)
Diabetes
, vol.55
, Issue.7
, pp. 2015-2020
-
-
Raubenheimer, P.J.1
Nyirenda, M.J.2
Walker, B.R.3
-
87
-
-
84881372774
-
Cellular fatty acid metabolism and cancer
-
E. Currie, A. Schulze, R. Zechner, T.C. Walther, and R.V. Farese Jr. Cellular fatty acid metabolism and cancer Cell Metab 18 2013 153 161
-
(2013)
Cell Metab
, vol.18
, pp. 153-161
-
-
Currie, E.1
Schulze, A.2
Zechner, R.3
Walther, T.C.4
Farese, Jr.R.V.5
-
88
-
-
84858796689
-
Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR
-
A.C. Calkin, and P. Tontonoz Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR Nat Rev Mol Cell Biol 13 2012 213 224
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 213-224
-
-
Calkin, A.C.1
Tontonoz, P.2
-
89
-
-
84896924220
-
The role of liver X receptor in hepatic de novo lipogenesis and cross-talk with insulin and glucose signaling
-
Rodrigo Valenzuela Baez, InTech
-
Line M. Grønning-Wang, Christian Bindesbøll, and Hilde I. Nebb The role of liver X receptor in hepatic de novo lipogenesis and cross-talk with insulin and glucose signaling Rodrigo Valenzuela Baez, Lipid metabolism 2013 InTech 60
-
(2013)
Lipid Metabolism
, pp. 60
-
-
Grønning-Wang, L.M.1
Bindesbøll, C.2
Nebb, H.I.3
-
90
-
-
24144490445
-
LXRs regulate the balance between fat storage and oxidation
-
DOI 10.1016/j.cmet.2005.03.001, PII S1550413105000604
-
N.Y. Kalaany, K.C. Gauthier, A.M. Zavacki, P.P. Mammen, T. Kitazume, and J.A. Peterson et al. LXRs regulate the balance between fat storage and oxidation Cell Metab 1 2005 231 244 (Pubitemid 43960607)
-
(2005)
Cell Metabolism
, vol.1
, Issue.4
, pp. 231-244
-
-
Kalaany, N.Y.1
Gauthier, K.C.2
Zavacki, A.M.3
Mammen, P.P.A.4
Kitazume, T.5
Peterson, J.A.6
Horton, J.D.7
Garry, D.J.8
Bianco, A.C.9
Mangelsdorf, D.J.10
-
91
-
-
55849105651
-
Liver X receptors (LXR) as therapeutic targets in dyslipidemia
-
J. Beltowski Liver X receptors (LXR) as therapeutic targets in dyslipidemia Cardiovasc Ther 26 2008 297 316
-
(2008)
Cardiovasc Ther
, vol.26
, pp. 297-316
-
-
Beltowski, J.1
-
92
-
-
84866609881
-
Metabolism: LRH-1 is a transcriptional regulator of glucokinase in the liver
-
C. Wilson Metabolism: LRH-1 is a transcriptional regulator of glucokinase in the liver Nat Rev Endocrinol 8 2012 566
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 566
-
-
Wilson, C.1
-
93
-
-
84864752368
-
LRH-1-dependent glucose sensing determines intermediary metabolism in liver
-
M.H. Oosterveer, C. Mataki, H. Yamamoto, T. Harach, N. Moullan, and T.H. van Dijk et al. LRH-1-dependent glucose sensing determines intermediary metabolism in liver J Clin Invest 122 2012 2817 2826
-
(2012)
J Clin Invest
, vol.122
, pp. 2817-2826
-
-
Oosterveer, M.H.1
Mataki, C.2
Yamamoto, H.3
Harach, T.4
Moullan, N.5
Van Dijk, T.H.6
-
94
-
-
34547111086
-
A key role for orphan nuclear receptor liver receptor homologue-1 in activation of fatty acid synthase promoter by liver X receptor
-
DOI 10.1074/jbc.M702895200
-
K.E. Matsukuma, L. Wang, M.K. Bennett, and T.F. Osborne A key role for orphan nuclear receptor liver receptor homologue-1 in activation of fatty acid synthase promoter by liver X receptor J Biol Chem 282 2007 20164 20171 (Pubitemid 47099984)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.28
, pp. 20164-20171
-
-
Matsukuma, K.E.1
Wang, L.2
Bennett, M.K.3
Osborne, T.F.4
-
95
-
-
77950613528
-
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats
-
S. Cipriani, A. Mencarelli, G. Palladino, and S. Fiorucci FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats J Lipid Res 51 2010 771 784
-
(2010)
J Lipid Res
, vol.51
, pp. 771-784
-
-
Cipriani, S.1
Mencarelli, A.2
Palladino, G.3
Fiorucci, S.4
-
96
-
-
84876477803
-
Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance
-
Y. Ma, Y. Huang, L. Yan, M. Gao, and D. Liu Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance Pharm Res 30 2013 1447 1457
-
(2013)
Pharm Res
, vol.30
, pp. 1447-1457
-
-
Ma, Y.1
Huang, Y.2
Yan, L.3
Gao, M.4
Liu, D.5
-
97
-
-
78649576502
-
Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism
-
J. Gao, and W. Xie Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism Drug Metab Dispos 38 2010 2091 2095
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 2091-2095
-
-
Gao, J.1
Xie, W.2
-
99
-
-
84878543117
-
Focus on therapeutic strategies of nonalcoholic fatty liver disease
-
M. Durazzo, P. Belci, A. Collo, E. Grisoglio, and S. Bo Focus on therapeutic strategies of nonalcoholic fatty liver disease Int J Hepatol 2012 2012 464706
-
(2012)
Int J Hepatol
, vol.2012
, pp. 464706
-
-
Durazzo, M.1
Belci, P.2
Collo, A.3
Grisoglio, E.4
Bo, S.5
-
100
-
-
84859157277
-
Roles of PPARs in NAFLD: Potential therapeutic targets
-
A. Tailleux, K. Wouters, and B. Staels Roles of PPARs in NAFLD: potential therapeutic targets Biochim Biophys Acta 1821 2012 809 818
-
(2012)
Biochim Biophys Acta
, vol.1821
, pp. 809-818
-
-
Tailleux, A.1
Wouters, K.2
Staels, B.3
-
101
-
-
33644766913
-
PPARδ regulates glucose metabolism and insulin sensitivity
-
DOI 10.1073/pnas.0511253103
-
Chih-Hao Lee, Peter Olson, Andrea Hevener, Isaac Mehl, Ling-Wa Chong, and Jerrold M. Olefsky et al. PPARδ regulates glucose metabolism and insulin sensitivity Proc Natl Acad Sci USA 103 2006 3444 3449 (Pubitemid 43346488)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.9
, pp. 3444-3449
-
-
Lee, C.-H.1
Olson, P.2
Hevener, A.3
Mehl, I.4
Chong, L.-W.5
Olefsky, J.M.6
Gonzalez, F.J.7
Ham, J.8
Kang, H.9
Peters, J.M.10
Evans, R.M.11
-
102
-
-
0034052579
-
Peroxisome proliferator-activated receptor α is restricted to hepatic parenchymal cells, not Kupffer cells: Implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis
-
J.M. Peters, I. Rusyn, M.L. Rose, F.J. Gonzalez, and R.G. Thurman Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis Carcinogenesis 21 2000 823 826 (Pubitemid 30214043)
-
(2000)
Carcinogenesis
, vol.21
, Issue.4
, pp. 823-826
-
-
Peters, J.M.1
Rusyn, I.2
Rose, M.L.3
Gonzalez, F.J.4
Thurman, R.G.5
-
103
-
-
0034076888
-
The role of hepatic peroxisome proliferator-activated receptors (PPARs) in health and disease
-
DOI 10.1034/j.1600-0676.2000.020003191.x
-
L. Everett, A. Galli, and D. Crabb The role of hepatic peroxisome proliferator-activated receptors (PPARs) in health and disease Liver 20 2000 191 199 (Pubitemid 30342716)
-
(2000)
Liver
, vol.20
, Issue.3
, pp. 191-199
-
-
Everett, L.1
Galli, A.2
Crabb, D.3
-
104
-
-
0037221210
-
Peroxisome proliferator-activated receptor-β signaling contributes to enhanced proliferation of hepatic stellate cells
-
DOI 10.1053/gast.2003.50015
-
K. Hellemans, L. Michalik, A. Dittie, A. Knorr, K. Rombouts, and J. De Jong et al. Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells Gastroenterology 124 2003 184 201 (Pubitemid 36055351)
-
(2003)
Gastroenterology
, vol.124
, Issue.1
, pp. 184-201
-
-
Hellemans, K.1
Michalik, L.2
Dittie, A.3
Knorr, A.4
Rombouts, K.5
De Jong, J.6
Heirman, C.7
Quartier, E.8
Schuit, F.9
Wahli, W.10
Geerts, A.11
-
105
-
-
77954987061
-
PPARalpha: Energy combustion, hypolipidemia, inflammation and cancer
-
S.R. Pyper, N. Viswakarma, S. Yu, and J.K. Reddy PPARalpha: energy combustion, hypolipidemia, inflammation and cancer Nucl Recept Signal 8 2010 e002
-
(2010)
Nucl Recept Signal
, vol.8
, pp. 002
-
-
Pyper, S.R.1
Viswakarma, N.2
Yu, S.3
Reddy, J.K.4
-
106
-
-
84856139907
-
Peroxisome proliferator-activated receptor-alpha agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis
-
C.Z. Larter, M.M. Yeh, D.M. Van Rooyen, J. Brooling, K. Ghatora, and G.C. Farrell Peroxisome proliferator-activated receptor-alpha agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis J Gastroenterol Hepatol 27 2012 341 350
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 341-350
-
-
Larter, C.Z.1
Yeh, M.M.2
Van Rooyen, D.M.3
Brooling, J.4
Ghatora, K.5
Farrell, G.C.6
-
107
-
-
75449101395
-
Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity
-
R. Stienstra, F. Saudale, C. Duval, S. Keshtkar, J.E. Groener, and N. van Rooijen et al. Kupffer cells promote hepatic steatosis via interleukin-1beta- dependent suppression of peroxisome proliferator-activated receptor alpha activity Hepatology 51 2010 511 522
-
(2010)
Hepatology
, vol.51
, pp. 511-522
-
-
Stienstra, R.1
Saudale, F.2
Duval, C.3
Keshtkar, S.4
Groener, J.E.5
Van Rooijen, N.6
-
108
-
-
84859980069
-
Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: Implications for liver regeneration
-
M.A. Fernandez-Rojo, C. Restall, C. Ferguson, N. Martel, S. Martin, and M. Bosch et al. Caveolin-1 orchestrates the balance between glucose and lipid-dependent energy metabolism: implications for liver regeneration Hepatology 55 2012 1574 1584
-
(2012)
Hepatology
, vol.55
, pp. 1574-1584
-
-
Fernandez-Rojo, M.A.1
Restall, C.2
Ferguson, C.3
Martel, N.4
Martin, S.5
Bosch, M.6
-
109
-
-
84872161392
-
PPAR could contribute to the pathogenesis of hepatocellular carcinoma
-
O. Kimura, Y. Kondo, and T. Shimosegawa PPAR could contribute to the pathogenesis of hepatocellular carcinoma PPAR Res 2012 2012 574180
-
(2012)
PPAR Res
, vol.2012
, pp. 574180
-
-
Kimura, O.1
Kondo, Y.2
Shimosegawa, T.3
-
110
-
-
0030047806
-
Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat
-
DOI 10.1210/en.137.1.354
-
O. Braissant, F. Foufelle, C. Scotto, M. Dauca, and W. Wahli Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat Endocrinology 137 1996 354 366 (Pubitemid 26005011)
-
(1996)
Endocrinology
, vol.137
, Issue.1
, pp. 354-366
-
-
Braissant, O.1
Foufelle, F.2
Scotto, C.3
Dauca, M.4
Wahli, W.5
-
111
-
-
84867370115
-
PPARs in liver diseases and cancer: Epigenetic regulation by microRNAs
-
M. Peyrou, P. Ramadori, L. Bourgoin, and M. Foti PPARs in liver diseases and cancer: epigenetic regulation by microRNAs PPAR Res 2012 2012 757803
-
(2012)
PPAR Res
, vol.2012
, pp. 757803
-
-
Peyrou, M.1
Ramadori, P.2
Bourgoin, L.3
Foti, M.4
-
112
-
-
77952392529
-
Metabolic and nonmetabolic regulatory functions of peroxisome proliferator-activated receptor beta
-
P.A. Grimaldi Metabolic and nonmetabolic regulatory functions of peroxisome proliferator-activated receptor beta Curr Opin Lipidol 21 2010 186 191
-
(2010)
Curr Opin Lipidol
, vol.21
, pp. 186-191
-
-
Grimaldi, P.A.1
-
113
-
-
52949099182
-
PPAR-beta/delta agonists for Type 2 diabetes and dyslipidemia: An adopted orphan still looking for a home
-
A.N. Billin PPAR-beta/delta agonists for Type 2 diabetes and dyslipidemia: an adopted orphan still looking for a home Expert Opin Invest Drug 17 2008 1465 1471
-
(2008)
Expert Opin Invest Drug
, vol.17
, pp. 1465-1471
-
-
Billin, A.N.1
-
114
-
-
84861437351
-
Protection from liver fibrosis by a peroxisome proliferator-activated receptor delta agonist
-
K. Iwaisako, M. Haimerl, Y.H. Paik, K. Taura, Y. Kodama, and C. Sirlin et al. Protection from liver fibrosis by a peroxisome proliferator-activated receptor delta agonist Proc Natl Acad Sci USA 109 2012 E1369 E1376
-
(2012)
Proc Natl Acad Sci USA
, vol.109
-
-
Iwaisako, K.1
Haimerl, M.2
Paik, Y.H.3
Taura, K.4
Kodama, Y.5
Sirlin, C.6
-
115
-
-
1642524221
-
Peroxisome Proliferator-activated Receptor γ Induces a Phenotypic Switch from Activated to Quiescent Hepatic Stellate Cells
-
DOI 10.1074/jbc.M310284200
-
S. Hazra, S. Xiong, J. Wang, R.A. Rippe, V. Krishna, and K. Chatterjee et al. Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells J Biol Chem 279 2004 11392 11401 (Pubitemid 38401638)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.12
, pp. 11392-11401
-
-
Hazra, S.1
Xiong, S.2
Wang, J.3
Rippe, R.A.4
Chatterjee, V.K.K.5
Tsukamoto, H.6
-
116
-
-
2942719049
-
Regulation of fatty acid transport by fatty acid translocase/CD36
-
DOI 10.1079/PNS2004331
-
A. Bonen, S.E. Campbell, C.R. Benton, A. Chabowski, S.L. Coort, and X.X. Han et al. Regulation of fatty acid transport by fatty acid translocase/CD36 Proc Nutr Soc 63 2004 245 249 (Pubitemid 38787473)
-
(2004)
Proceedings of the Nutrition Society
, vol.63
, Issue.2
, pp. 245-249
-
-
Bonen, A.1
Campbell, S.E.2
Benton, C.R.3
Chabowski, A.4
Coort, S.L.M.5
Han, X.-X.6
Koonen, D.P.Y.7
Glatz, J.F.C.8
Luiken, J.J.F.P.9
-
117
-
-
80051706346
-
Role for PPARgamma in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts
-
E. Moran-Salvador, M. Lopez-Parra, V. Garcia-Alonso, E. Titos, M. Martinez-Clemente, and A. Gonzalez-Periz et al. Role for PPARgamma in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts FASEB J 25 2011 2538 2550
-
(2011)
FASEB J
, vol.25
, pp. 2538-2550
-
-
Moran-Salvador, E.1
Lopez-Parra, M.2
Garcia-Alonso, V.3
Titos, E.4
Martinez-Clemente, M.5
Gonzalez-Periz, A.6
-
118
-
-
84888285959
-
Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
-
B. Staels, A. Rubenstrunk, B. Noel, G. Rigou, P. Delataille, and L.J. Millatt et al. Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis Hepatology 2013
-
(2013)
Hepatology
-
-
Staels, B.1
Rubenstrunk, A.2
Noel, B.3
Rigou, G.4
Delataille, P.5
Millatt, L.J.6
-
119
-
-
78349261937
-
Gene expression changes induced by PPAR gamma agonists in animal and human liver
-
A. Rogue, C. Spire, M. Brun, N. Claude, and A. Guillouzo Gene expression changes induced by PPAR gamma agonists in animal and human liver PPAR Res 2010 2010 325183
-
(2010)
PPAR Res
, vol.2010
, pp. 325183
-
-
Rogue, A.1
Spire, C.2
Brun, M.3
Claude, N.4
Guillouzo, A.5
-
120
-
-
77952731389
-
Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro
-
J. Yu, B. Shen, E.S. Chu, N. Teoh, K.F. Cheung, and C.W. Wu et al. Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro Hepatology 51 2010 2008 2019
-
(2010)
Hepatology
, vol.51
, pp. 2008-2019
-
-
Yu, J.1
Shen, B.2
Chu, E.S.3
Teoh, N.4
Cheung, K.F.5
Wu, C.W.6
-
121
-
-
0035200209
-
Activation of retinoic X receptor and peroxisome proliferator-activated receptor-γ inhibits nitric oxide and tumor necrosis factor-α production in rat Kupffer cells
-
DOI 10.1053/jhep.2001.21145
-
K. Uchimura, M. Nakamuta, M. Enjoji, T. Irie, R. Sugimoto, and T. Muta et al. Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells Hepatology 33 2001 91 99 (Pubitemid 32016891)
-
(2001)
Hepatology
, vol.33
, Issue.1
, pp. 91-99
-
-
Uchimura, K.1
Nakamuta, M.2
Enjoji, M.3
Irie, T.4
Sugimoto, R.5
Muta, T.6
Iwamoto, H.7
Nawata, H.8
-
122
-
-
84884871131
-
Amplified inhibition of stellate cell activation pathways by PPAR-gamma, RAR and RXR agonists
-
E. Sharvit, S. Abramovitch, S. Reif, and R. Bruck Amplified inhibition of stellate cell activation pathways by PPAR-gamma, RAR and RXR agonists PLoS One 8 2013 e76541
-
(2013)
PLoS One
, vol.8
, pp. 76541
-
-
Sharvit, E.1
Abramovitch, S.2
Reif, S.3
Bruck, R.4
-
123
-
-
2642549921
-
Liver-enriched transcription factors in liver function and development. Part II: The C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation
-
DOI 10.1124/pr.56.2.5
-
H. Schrem, J. Klempnauer, and J. Borlak Liver-enriched transcription factors in liver function and development. Part II: The C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation Pharmacol Rev 56 2004 291 330 (Pubitemid 38720832)
-
(2004)
Pharmacological Reviews
, vol.56
, Issue.2
, pp. 291-330
-
-
Schrem, H.1
Klempnauer, J.2
Borlak, J.3
-
124
-
-
34547824172
-
Foxo1 links insulin signaling to C/EBPα and regulates gluconeogenesis during liver development
-
DOI 10.1038/sj.emboj.7601784, PII 7601784
-
K. Sekine, Y.R. Chen, N. Kojima, K. Ogata, A. Fukamizu, and A. Miyajima Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development EMBO J 26 2007 3607 3615 (Pubitemid 47236870)
-
(2007)
EMBO Journal
, vol.26
, Issue.15
, pp. 3607-3615
-
-
Sekine, K.1
Chen, Y.-R.2
Kojima, N.3
Ogata, K.4
Fukamizu, A.5
Miyajima, A.6
-
125
-
-
7244221588
-
Disruption of hepatic C/EBPα results in impaired glucose tolerance and age-dependent hepatosteatosis
-
DOI 10.1074/jbc.M405177200
-
Y. Inoue, J. Inoue, G. Lambert, S.H. Yim, and F.J. Gonzalez Disruption of hepatic C/EBPalpha results in impaired glucose tolerance and age-dependent hepatosteatosis J Biol Chem 279 2004 44740 44748 (Pubitemid 39430884)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.43
, pp. 44740-44748
-
-
Inoue, Y.1
Inoue, J.2
Lambert, G.3
Yim, S.H.4
Gonzalez, F.J.5
-
126
-
-
84875811610
-
Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis
-
J. Jin, P. Iakova, M. Breaux, E. Sullivan, N. Jawanmardi, and D. Chen et al. Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis Cell Rep 3 2013 831 843
-
(2013)
Cell Rep
, vol.3
, pp. 831-843
-
-
Jin, J.1
Iakova, P.2
Breaux, M.3
Sullivan, E.4
Jawanmardi, N.5
Chen, D.6
-
127
-
-
34248681601
-
CCAAT/enhancing binding protein β deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis
-
DOI 10.1002/hep.21614
-
S.M. Rahman, J.M. Schroeder-Gloeckler, R.C. Janssen, H. Jiang, I. Qadri, and K.N. Maclean et al. CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis Hepatology 45 2007 1108 1117 (Pubitemid 46775772)
-
(2007)
Hepatology
, vol.45
, Issue.5
, pp. 1108-1117
-
-
Rahman, S.M.1
Schroeder-Gloeckler, J.M.2
Janssen, R.C.3
Jiang, H.4
Qadri, I.5
Maclean, K.N.6
Friedman, J.E.7
-
128
-
-
0036200587
-
Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression
-
DOI 10.1124/pr.54.1.129
-
H. Schrem, J. Klempnauer, and J. Borlak Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression Pharmacol Rev 54 2002 129 158 (Pubitemid 34208830)
-
(2002)
Pharmacological Reviews
, vol.54
, Issue.1
, pp. 129-158
-
-
Schrem, H.1
Klempnauer, J.2
Borlak, J.3
-
129
-
-
64749097992
-
Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs
-
X. Xie, H. Liao, H. Dang, W. Pang, Y. Guan, and X. Wang et al. Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs Mol Endocrinol 23 2009 434 443
-
(2009)
Mol Endocrinol
, vol.23
, pp. 434-443
-
-
Xie, X.1
Liao, H.2
Dang, H.3
Pang, W.4
Guan, Y.5
Wang, X.6
-
132
-
-
61949147670
-
Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist
-
E.E. Cable, P.D. Finn, J.W. Stebbins, J. Hou, B.R. Ito, and P.D. van Poelje et al. Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist Hepatology 49 2009 407 417
-
(2009)
Hepatology
, vol.49
, pp. 407-417
-
-
Cable, E.E.1
Finn, P.D.2
Stebbins, J.W.3
Hou, J.4
Ito, B.R.5
Van Poelje, P.D.6
-
133
-
-
77950863893
-
Nontriglyceride hepatic lipotoxicity: The new paradigm for the pathogenesis of NASH
-
B.A. Neuschwander-Tetri Nontriglyceride hepatic lipotoxicity: the new paradigm for the pathogenesis of NASH Curr Gastroenterol Rep 12 2010 49 56
-
(2010)
Curr Gastroenterol Rep
, vol.12
, pp. 49-56
-
-
Neuschwander-Tetri, B.A.1
-
134
-
-
37349081571
-
Role of ChREBP in hepatic steatosis and insulin resistance
-
DOI 10.1016/j.febslet.2007.07.084, PII S0014579307008757
-
P.D. Denechaud, R. Dentin, J. Girard, and C. Postic Role of ChREBP in hepatic steatosis and insulin resistance FEBS Lett 582 2008 68 73 (Pubitemid 350297238)
-
(2008)
FEBS Letters
, vol.582
, Issue.1
, pp. 68-73
-
-
Denechaud, P.-D.1
Dentin, R.2
Girard, J.3
Postic, C.4
-
135
-
-
84861809881
-
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
-
F. Benhamed, P.D. Denechaud, M. Lemoine, C. Robichon, M. Moldes, and J. Bertrand-Michel et al. The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans J Clin Invest 122 2012 2176 2194
-
(2012)
J Clin Invest
, vol.122
, pp. 2176-2194
-
-
Benhamed, F.1
Denechaud, P.D.2
Lemoine, M.3
Robichon, C.4
Moldes, M.5
Bertrand-Michel, J.6
-
136
-
-
84876998618
-
Novel insights into ChREBP regulation and function
-
G. Filhoulaud, S. Guilmeau, R. Dentin, J. Girard, and C. Postic Novel insights into ChREBP regulation and function Trends Endocrinol Metab 24 2013 257 268
-
(2013)
Trends Endocrinol Metab
, vol.24
, pp. 257-268
-
-
Filhoulaud, G.1
Guilmeau, S.2
Dentin, R.3
Girard, J.4
Postic, C.5
-
137
-
-
84867067610
-
Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase
-
J.L. Owen, Y. Zhang, S.H. Bae, M.S. Farooqi, G. Liang, and R.E. Hammer et al. Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase Proc Natl Acad Sci USA 109 2012 16184 16189
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 16184-16189
-
-
Owen, J.L.1
Zhang, Y.2
Bae, S.H.3
Farooqi, M.S.4
Liang, G.5
Hammer, R.E.6
-
138
-
-
77957302090
-
Hepatic steatosis: A role for de novo lipogenesis and the transcription factor SREBP-1c
-
P. Ferre, and F. Foufelle Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c Diabetes Obes Metab 12 Suppl 2 2010 83 92
-
(2010)
Diabetes Obes Metab
, vol.12
, Issue.SUPPL.2
, pp. 83-92
-
-
Ferre, P.1
Foufelle, F.2
-
139
-
-
79960960007
-
Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways
-
J.L. Yecies, H.H. Zhang, S. Menon, S. Liu, D. Yecies, and A.I. Lipovsky et al. Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways Cell Metab 14 2011 21 32
-
(2011)
Cell Metab
, vol.14
, pp. 21-32
-
-
Yecies, J.L.1
Zhang, H.H.2
Menon, S.3
Liu, S.4
Yecies, D.5
Lipovsky, A.I.6
-
140
-
-
84861043736
-
Connecting mTORC1 signaling to SREBP-1 activation
-
I. Bakan, and M. Laplante Connecting mTORC1 signaling to SREBP-1 activation Curr Opin Lipidol 23 2012 226 234
-
(2012)
Curr Opin Lipidol
, vol.23
, pp. 226-234
-
-
Bakan, I.1
Laplante, M.2
-
141
-
-
84863086400
-
Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice
-
X. Guo, H. Li, H. Xu, V. Halim, W. Zhang, and H. Wang et al. Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice PLoS One 7 2012 e39286
-
(2012)
PLoS One
, vol.7
, pp. 39286
-
-
Guo, X.1
Li, H.2
Xu, H.3
Halim, V.4
Zhang, W.5
Wang, H.6
-
142
-
-
33746959419
-
Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets
-
DOI 10.1111/j.1600-0854.2006.00465.x
-
S. Turro, M. Ingelmo-Torres, J.M. Estanyol, F. Tebar, M.A. Fernandez, and C.V. Albor et al. Identification and characterization of associated with lipid droplet protein 1: a novel membrane-associated protein that resides on hepatic lipid droplets Traffic 7 2006 1254 1269 (Pubitemid 44204000)
-
(2006)
Traffic
, vol.7
, Issue.9
, pp. 1254-1269
-
-
Turro, S.1
Ingelmo-Torres, M.2
Estanyol, J.M.3
Tebar, F.4
Fernandez, M.A.5
Albor, C.V.6
Gaus, K.7
Grewal, T.8
Enrich, C.9
Pol, A.10
-
143
-
-
84896963551
-
Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: Potential role in alcohol-impaired LD metabolism
-
K. Rasineni, B.L. McVicker, D.J. Tuma, M.A. McNiven, and C.A. Casey Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism Alcohol Clin Exp Res 2013
-
(2013)
Alcohol Clin Exp Res
-
-
Rasineni, K.1
McVicker, B.L.2
Tuma, D.J.3
McNiven, M.A.4
Casey, C.A.5
-
144
-
-
84861742465
-
LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid beta-oxidation of lipid droplets
-
H. Li, Y. Song, L.J. Zhang, Y. Gu, F.F. Li, and S.Y. Pan et al. LSDP5 enhances triglyceride storage in hepatocytes by influencing lipolysis and fatty acid beta-oxidation of lipid droplets PLoS One 7 2012 e36712
-
(2012)
PLoS One
, vol.7
, pp. 36712
-
-
Li, H.1
Song, Y.2
Zhang, L.J.3
Gu, Y.4
Li, F.F.5
Pan, S.Y.6
-
145
-
-
84862313783
-
The proteomics of lipid droplets: Structure, dynamics, and functions of the organelle conserved from bacteria to humans
-
L. Yang, Y. Ding, Y. Chen, S. Zhang, C. Huo, and Y. Wang et al. The proteomics of lipid droplets: structure, dynamics, and functions of the organelle conserved from bacteria to humans J Lipid Res 53 2012 1245 1253
-
(2012)
J Lipid Res
, vol.53
, pp. 1245-1253
-
-
Yang, L.1
Ding, Y.2
Chen, Y.3
Zhang, S.4
Huo, C.5
Wang, Y.6
-
147
-
-
34147152663
-
Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic
-
DOI 10.1194/jlr.M600413-JLR200
-
R. Bartz, W.H. Li, B. Venables, J.K. Zehmer, M.R. Roth, and R. Welti et al. Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic J Lipid Res 48 2007 837 847 (Pubitemid 46557888)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.4
, pp. 837-847
-
-
Bartz, R.1
Li, W.-H.2
Venables, B.3
Zehmer, J.K.4
Roth, M.R.5
Welti, R.6
Anderson, R.G.W.7
Liu, P.8
Chapman, K.D.9
-
148
-
-
0037113954
-
The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition
-
DOI 10.1074/jbc.M207712200
-
K. Tauchi-Sato, S. Ozeki, T. Houjou, R. Taguchi, and T. Fujimoto The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition J Biol Chem 277 2002 44507 44512 (Pubitemid 36157885)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 44507-44512
-
-
Tauchi-Sato, K.1
Ozeki, S.2
Houjou, T.3
Taguchi, R.4
Fujimoto, T.5
-
149
-
-
0035810964
-
Lipid droplets: Proteins floating on a pool of fat
-
D.A. Brown Lipid droplets: proteins floating on a pool of fat Curr Biol 11 2001 R446 R449
-
(2001)
Curr Biol
, vol.11
-
-
Brown, D.A.1
-
150
-
-
38049184643
-
The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology
-
K.M. Szymanski, D. Binns, R. Bartz, N.V. Grishin, W.P. Li, and A.K. Agarwal et al. The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology Proc Natl Acad Sci USA 104 2007 20890 20895
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20890-20895
-
-
Szymanski, K.M.1
Binns, D.2
Bartz, R.3
Grishin, N.V.4
Li, W.P.5
Agarwal, A.K.6
-
151
-
-
78650388357
-
Seipin is a discrete homooligomer
-
D. Binns, S. Lee, C.L. Hilton, Q.X. Jiang, and J.M. Goodman Seipin is a discrete homooligomer Biochemistry 49 2010 10747 10755
-
(2010)
Biochemistry
, vol.49
, pp. 10747-10755
-
-
Binns, D.1
Lee, S.2
Hilton, C.L.3
Jiang, Q.X.4
Goodman, J.M.5
-
152
-
-
81855177041
-
Molecular characterization of seipin and its mutants: Implications for seipin in triacylglycerol synthesis
-
W. Fei, H. Li, G. Shui, T.S. Kapterian, C. Bielby, and X. Du et al. Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis J Lipid Res 52 2011 2136 2147
-
(2011)
J Lipid Res
, vol.52
, pp. 2136-2147
-
-
Fei, W.1
Li, H.2
Shui, G.3
Kapterian, T.S.4
Bielby, C.5
Du, X.6
-
153
-
-
39049151385
-
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast
-
DOI 10.1083/jcb.200711136
-
W. Fei, G. Shui, B. Gaeta, X. Du, L. Kuerschner, and P. Li et al. Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast J Cell Biol 180 2008 473 482 (Pubitemid 351240697)
-
(2008)
Journal of Cell Biology
, vol.180
, Issue.3
, pp. 473-482
-
-
Fei, W.1
Shui, G.2
Gaeta, B.3
Du, X.4
Kuerschner, L.5
Li, P.6
Brown, A.J.7
Wenk, M.R.8
Parton, R.G.9
Yang, H.10
-
154
-
-
79955629359
-
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation
-
Y. Tian, J. Bi, G. Shui, Z. Liu, Y. Xiang, and Y. Liu et al. Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation PLoS Genet 7 2011 e1001364
-
(2011)
PLoS Genet
, vol.7
, pp. 1001364
-
-
Tian, Y.1
Bi, J.2
Shui, G.3
Liu, Z.4
Xiang, Y.5
Liu, Y.6
-
155
-
-
34547216748
-
A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum
-
DOI 10.1038/nature06004, PII NATURE06004
-
H.L. Ploegh A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum Nature 448 2007 435 438 (Pubitemid 47123517)
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 435-438
-
-
Ploegh, H.L.1
-
158
-
-
67349106073
-
Perilipin A and the control of triacylglycerol metabolism
-
D.L. Brasaemle, V. Subramanian, A. Garcia, A. Marcinkiewicz, and A. Rothenberg Perilipin A and the control of triacylglycerol metabolism Mol Cell Biochem 326 2009 15 21
-
(2009)
Mol Cell Biochem
, vol.326
, pp. 15-21
-
-
Brasaemle, D.L.1
Subramanian, V.2
Garcia, A.3
Marcinkiewicz, A.4
Rothenberg, A.5
-
159
-
-
84867155451
-
Update on perilipin polymorphisms and obesity
-
C.E. Smith, and J.M. Ordovas Update on perilipin polymorphisms and obesity Nutr Rev 70 2012 611 621
-
(2012)
Nutr Rev
, vol.70
, pp. 611-621
-
-
Smith, C.E.1
Ordovas, J.M.2
-
160
-
-
80455135722
-
Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria
-
H. Wang, U. Sreenevasan, H. Hu, A. Saladino, B.M. Polster, and L.M. Lund et al. Perilipin 5, a lipid droplet-associated protein, provides physical and
-
(2011)
J Lipid Res
, vol.52
, pp. 2159-2168
-
-
Wang, H.1
Sreenevasan, U.2
Hu, H.3
Saladino, A.4
Polster, B.M.5
Lund, L.M.6
-
161
-
-
77950607704
-
Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins
-
A.R. Kimmel, D.L. Brasaemle, M. McAndrews-Hill, C. Sztalryd, and C. Londos Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins J Lipid Res 51 2010 468 471
-
(2010)
J Lipid Res
, vol.51
, pp. 468-471
-
-
Kimmel, A.R.1
Brasaemle, D.L.2
McAndrews-Hill, M.3
Sztalryd, C.4
Londos, C.5
-
162
-
-
84864862383
-
Opposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation
-
X. Li, J. Ye, L. Zhou, W. Gu, E.A. Fisher, and P. Li Opposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation J Lipid Res 53 2012 1877 1889
-
(2012)
J Lipid Res
, vol.53
, pp. 1877-1889
-
-
Li, X.1
Ye, J.2
Zhou, L.3
Gu, W.4
Fisher, E.A.5
Li, P.6
-
163
-
-
30544452121
-
Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet
-
DOI 10.1016/j.bbrc.2005.12.121, PII S0006291X05028792
-
W. Motomura, M. Inoue, T. Ohtake, N. Takahashi, M. Nagamine, and S. Tanno et al. Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet Biochem Biophys Res Commun 340 2006 1111 1118 (Pubitemid 43083393)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.340
, Issue.4
, pp. 1111-1118
-
-
Motomura, W.1
Inoue, M.2
Ohtake, T.3
Takahashi, N.4
Nagamine, M.5
Tanno, S.6
Kohgo, Y.7
Okumura, T.8
-
164
-
-
84873261154
-
Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression
-
Y. Imai, S. Boyle, G.M. Varela, E. Caron, X. Yin, and R. Dhir et al. Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression Physiol Genomics 44 2012 1125 1131
-
(2012)
Physiol Genomics
, vol.44
, pp. 1125-1131
-
-
Imai, Y.1
Boyle, S.2
Varela, G.M.3
Caron, E.4
Yin, X.5
Dhir, R.6
-
165
-
-
84859740874
-
Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice
-
R.M. Carr, R.T. Patel, V. Rao, R. Dhir, M.J. Graham, and R.M. Crooke et al. Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice Am J Physiol Regul Integr Comp Physiol 302 2012 R996 R1003
-
(2012)
Am J Physiol Regul Integr Comp Physiol
, vol.302
-
-
Carr, R.M.1
Patel, R.T.2
Rao, V.3
Dhir, R.4
Graham, M.J.5
Crooke, R.M.6
-
166
-
-
29644442801
-
Regulated localization of Rab18 to lipid droplets: Effects of lipolytic stimulation and inhibition of lipid droplet catabolism
-
DOI 10.1074/jbc.M506651200
-
S. Martin, K. Driessen, S.J. Nixon, M. Zerial, and R.G. Parton Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism J Biol Chem 280 2005 42325 42335 (Pubitemid 43023204)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.51
, pp. 42325-42335
-
-
Martin, S.1
Driessen, K.2
Nixon, S.J.3
Zerial, M.4
Parton, R.G.5
-
167
-
-
57649116078
-
The gregarious lipid droplet
-
J.M. Goodman The gregarious lipid droplet J Biol Chem 283 2008 28005 28009
-
(2008)
J Biol Chem
, vol.283
, pp. 28005-28009
-
-
Goodman, J.M.1
-
168
-
-
79960904395
-
Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity
-
M.R. Pulido, A. Diaz-Ruiz, Y. Jimenez-Gomez, S. Garcia-Navarro, F. Gracia-Navarro, and F. Tinahones et al. Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity PLoS One 6 2011 e22931
-
(2011)
PLoS One
, vol.6
, pp. 22931
-
-
Pulido, M.R.1
Diaz-Ruiz, A.2
Jimenez-Gomez, Y.3
Garcia-Navarro, S.4
Gracia-Navarro, F.5
Tinahones, F.6
-
169
-
-
21644459401
-
Rab18 localizes to lipid droplets and induces their close apposition to the endoplasmic reticulum-derived membrane
-
DOI 10.1242/jcs.02401
-
S. Ozeki, J. Cheng, K. Tauchi-Sato, N. Hatano, H. Taniguchi, and T. Fujimoto Rab18 localizes to lipid droplets and induces their close apposition to the endoplasmic reticulum-derived membrane J Cell Sci 118 2005 2601 2611 (Pubitemid 40932886)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.12
, pp. 2601-2611
-
-
Ozeki, S.1
Cheng, J.2
Tauchi-Sato, K.3
Hatano, N.4
Taniguchi, H.5
Fujimoto, T.6
-
170
-
-
20444377641
-
A sixth sense for Rab5
-
A.M. van der Bliek A sixth sense for Rab5 Nat Cell Biol 7 2005 548 550
-
(2005)
Nat Cell Biol
, vol.7
, pp. 548-550
-
-
Van Der Bliek, A.M.1
-
171
-
-
34249674057
-
Rab-regulated interaction of early endosomes with lipid droplets
-
DOI 10.1016/j.bbamcr.2007.02.004, PII S0167488907000328
-
P. Liu, R. Bartz, J.K. Zehmer, Y.S. Ying, M. Zhu, and G. Serrero et al. Rab-regulated interaction of early endosomes with lipid droplets Biochim Biophys Acta 1773 2007 784 793 (Pubitemid 46829428)
-
(2007)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1773
, Issue.6
, pp. 784-793
-
-
Liu, P.1
Bartz, R.2
Zehmer, J.K.3
Ying, Y.-s.4
Zhu, M.5
Serrero, G.6
Anderson, R.G.W.7
-
172
-
-
84863157590
-
Rab32 is important for autophagy and lipid storage in Drosophila
-
C. Wang, Z. Liu, and X. Huang Rab32 is important for autophagy and lipid storage in Drosophila PLoS One 7 2012 e32086
-
(2012)
PLoS One
, vol.7
, pp. 32086
-
-
Wang, C.1
Liu, Z.2
Huang, X.3
-
173
-
-
84874054093
-
Fasting regulates FSP27 expression in the liver
-
V. Puri Fasting regulates FSP27 expression in the liver J Lipid Res 54 2013 569 570
-
(2013)
J Lipid Res
, vol.54
, pp. 569-570
-
-
Puri, V.1
-
174
-
-
84874050218
-
Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate
-
A. Vila-Brau, A.L. De Sousa-Coelho, J.F. Goncalves, D. Haro, and P.F. Marrero Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate J Lipid Res 54 2013 592 601
-
(2013)
J Lipid Res
, vol.54
, pp. 592-601
-
-
Vila-Brau, A.1
De Sousa-Coelho, A.L.2
Goncalves, J.F.3
Haro, D.4
Marrero, P.F.5
-
175
-
-
78649805641
-
Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1
-
T. Gimm, M. Wiese, B. Teschemacher, A. Deggerich, J. Schodel, and K.X. Knaup et al. Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1 FASEB J 24 2010 4443 4458
-
(2010)
FASEB J
, vol.24
, pp. 4443-4458
-
-
Gimm, T.1
Wiese, M.2
Teschemacher, B.3
Deggerich, A.4
Schodel, J.5
Knaup, K.X.6
-
176
-
-
73149109067
-
Hypoxia and non-alcoholic fatty liver disease
-
C.D. Byrne Hypoxia and non-alcoholic fatty liver disease Clin Sci (Lond) 118 2009 397 400
-
(2009)
Clin Sci (Lond)
, vol.118
, pp. 397-400
-
-
Byrne, C.D.1
-
177
-
-
51349133312
-
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways
-
T. Nitta, J.S. Kim, D. Mohuczy, and K.E. Behrns Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways Hepatology 48 2008 909 919
-
(2008)
Hepatology
, vol.48
, pp. 909-919
-
-
Nitta, T.1
Kim, J.S.2
Mohuczy, D.3
Behrns, K.E.4
-
178
-
-
84896919536
-
The expression and secretion of vimentin in the progression of non-alcoholic steatohepatitis
-
S.J. Lee, S.Y. Choi, and O.S. Kwon The expression and secretion of vimentin in the progression of non-alcoholic steatohepatitis BMB Rep 2013
-
(2013)
BMB Rep
-
-
Lee, S.J.1
Choi, S.Y.2
Kwon, O.S.3
-
179
-
-
79960147839
-
Seipin ablation in mice results in severe generalized lipodystrophy
-
X. Cui, Y. Wang, Y. Tang, Y. Liu, L. Zhao, and J. Deng et al. Seipin ablation in mice results in severe generalized lipodystrophy Hum Mol Genet 20 2011 3022 3030
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3022-3030
-
-
Cui, X.1
Wang, Y.2
Tang, Y.3
Liu, Y.4
Zhao, L.5
Deng, J.6
-
180
-
-
38349127584
-
Evolutionarily conserved gene family important for fat storage
-
B. Kadereit, P. Kumar, W.J. Wang, D. Miranda, E.L. Snapp, and N. Severina et al. Evolutionarily conserved gene family important for fat storage Proc Natl Acad Sci USA 105 2008 94 99
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 94-99
-
-
Kadereit, B.1
Kumar, P.2
Wang, W.J.3
Miranda, D.4
Snapp, E.L.5
Severina, N.6
-
181
-
-
33747853190
-
Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway
-
DOI 10.1016/j.cmet.2006.08.005, PII S1550413106002750
-
B.N. Finck, M.C. Gropler, Z. Chen, T.C. Leone, M.A. Croce, and T.E. Harris et al. Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway Cell Metab 4 2006 199 210 (Pubitemid 44283957)
-
(2006)
Cell Metabolism
, vol.4
, Issue.3
, pp. 199-210
-
-
Finck, B.N.1
Gropler, M.C.2
Chen, Z.3
Leone, T.C.4
Croce, M.A.5
Harris, T.E.6
Lawrence Jr., J.C.7
Kelly, D.P.8
-
182
-
-
84876899536
-
Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus
-
W. Yang, S. Thein, X. Guo, F. Xu, B. Venkatesh, and S. Sugii et al. Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus Biochem J 452 2013 37 44
-
(2013)
Biochem J
, vol.452
, pp. 37-44
-
-
Yang, W.1
Thein, S.2
Guo, X.3
Xu, F.4
Venkatesh, B.5
Sugii, S.6
-
183
-
-
83755183360
-
Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation
-
D.A. Gross, C. Zhan, and D.L. Silver Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation Proc Natl Acad Sci USA 108 2011 19581 19586
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19581-19586
-
-
Gross, D.A.1
Zhan, C.2
Silver, D.L.3
-
184
-
-
77956509037
-
Structural insights into triglyceride storage mediated by fat storage-inducing transmembrane (FIT) protein 2
-
D.A. Gross, E.L. Snapp, and D.L. Silver Structural insights into triglyceride storage mediated by fat storage-inducing transmembrane (FIT) protein 2 PLoS One 5 2010 e10796
-
(2010)
PLoS One
, vol.5
, pp. 10796
-
-
Gross, D.A.1
Snapp, E.L.2
Silver, D.L.3
-
185
-
-
34548486955
-
The SPFH domain-containing proteins: More than lipid raft markers
-
DOI 10.1016/j.tcb.2007.06.005, PII S0962892407001584
-
D.T. Browman, M.B. Hoegg, and S.M. Robbins The SPFH domain-containing proteins: more than lipid raft markers Trends Cell Biol 17 2007 394 402 (Pubitemid 47375100)
-
(2007)
Trends in Cell Biology
, vol.17
, Issue.8
, pp. 394-402
-
-
Browman, D.T.1
Hoegg, M.B.2
Robbins, S.M.3
-
186
-
-
66349087046
-
The challenge of lipid rafts
-
L.J. Pike The challenge of lipid rafts J Lipid Res 50 Suppl 2009 S323 S328
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Pike, L.J.1
-
187
-
-
33847652195
-
Raft association and lipid droplet targeting of flotillins are independent of caveolin
-
DOI 10.1515/BC.2007.034
-
L. Rajendran, S. Le Lay, and H. Illges Raft association and lipid droplet targeting of flotillins are independent of caveolin Biol Chem 388 2007 307 314 (Pubitemid 46364470)
-
(2007)
Biological Chemistry
, vol.388
, Issue.3
, pp. 307-314
-
-
Rajendran, L.1
Le Lay, S.2
Illges, H.3
-
188
-
-
84896976460
-
-
The AOCS Lipid Library [Internet]; [cited 19.11.2013]
-
Kelly K, Jacobs RL. Phospholpid biosynthesis. The AOCS Lipid Library [Internet]; 2011. < http://lipidlibrary.aocs.org/animbio/phospholipids/index. htm > [cited 19.11.2013].
-
(2011)
Phospholpid Biosynthesis
-
-
Kelly, K.1
Jacobs, R.L.2
-
189
-
-
34547939090
-
Lipids and lipid modifications in the regulation of membrane traffic
-
DOI 10.1016/j.ceb.2007.06.003, PII S095506740700097X
-
V. Haucke, and G. Di Paolo Lipids and lipid modifications in the regulation of membrane traffic Curr Opin Cell Biol 19 2007 426 435 (Pubitemid 47268765)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.4
, pp. 426-435
-
-
Haucke, V.1
Di Paolo, G.2
-
190
-
-
0346099345
-
Dynamic and Regulated Association of Caveolin with Lipid Bodies: Modulation of Lipid Body Motility and Function by a Dominant Negative Mutant
-
DOI 10.1091/mbc.E03-06-0368
-
A. Pol, S. Martin, M.A. Fernandez, C. Ferguson, A. Carozzi, and R. Luetterforst et al. Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant Mol Biol Cell 15 2004 99 110 (Pubitemid 38044947)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.1
, pp. 99-110
-
-
Pol, A.1
Martin, S.2
Fernandez, M.A.3
Ferguson, C.4
Carozzi, A.5
Luetterforst, R.6
Enrich, C.7
Parton, R.G.8
-
191
-
-
79953741782
-
Alcohol and lipid traffic don't mix
-
M.A. McNiven, and C.A. Casey Alcohol and lipid traffic don't mix Hepatology 53 2011 1073 1075
-
(2011)
Hepatology
, vol.53
, pp. 1073-1075
-
-
McNiven, M.A.1
Casey, C.A.2
-
192
-
-
35348847785
-
Annexin a6-Induced alterations in cholesterol transport and caveolin export from the Golgi complex
-
DOI 10.1111/j.1600-0854.2007.00640.x
-
L. Cubells, S. Vila de Muga, F. Tebar, P. Wood, R. Evans, and M. Ingelmo-Torres et al. Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex Traffic 8 2007 1568 1589 (Pubitemid 47578362)
-
(2007)
Traffic
, vol.8
, Issue.11
, pp. 1568-1589
-
-
Cubells, L.1
Vila De Muga, S.2
Tebar, F.3
Wood, P.4
Evans, R.5
Ingelmo-torres, M.6
Calvo, M.7
Gaus, K.8
Pol, A.9
Grewal, T.10
Enrich, C.11
-
193
-
-
84866382121
-
The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface
-
N. Xu, S.O. Zhang, R.A. Cole, S.A. McKinney, F. Guo, and J.T. Haas et al. The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface J Cell Biol 198 2012 895 911
-
(2012)
J Cell Biol
, vol.198
, pp. 895-911
-
-
Xu, N.1
Zhang, S.O.2
Cole, R.A.3
McKinney, S.A.4
Guo, F.5
Haas, J.T.6
-
194
-
-
80054678271
-
Evidence that diacylglycerol acyltransferase 1 (DGAT1) has dual membrane topology in the endoplasmic reticulum of HepG2 cells
-
H.R. Wurie, L. Buckett, and V.A. Zammit Evidence that diacylglycerol acyltransferase 1 (DGAT1) has dual membrane topology in the endoplasmic reticulum of HepG2 cells J Biol Chem 286 2011 36238 36247
-
(2011)
J Biol Chem
, vol.286
, pp. 36238-36247
-
-
Wurie, H.R.1
Buckett, L.2
Zammit, V.A.3
-
195
-
-
84892543665
-
An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER
-
D.F. Markgraf, R.W. Klemm, M. Junker, H.K. Hannibal-Bach, C.S. Ejsing, and T.A. Rapoport An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER Cell Rep 6 2014 44 55
-
(2014)
Cell Rep
, vol.6
, pp. 44-55
-
-
Markgraf, D.F.1
Klemm, R.W.2
Junker, M.3
Hannibal-Bach, H.K.4
Ejsing, C.S.5
Rapoport, T.A.6
-
196
-
-
84872840929
-
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
-
J.A. Olzmann, C.M. Richter, and R.R. Kopito Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover Proc Natl Acad Sci USA 110 2013 1345 1350
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1345-1350
-
-
Olzmann, J.A.1
Richter, C.M.2
Kopito, R.R.3
-
197
-
-
69449095908
-
Coatomer-dependent protein delivery to lipid droplets
-
K.G. Soni, G.A. Mardones, R. Sougrat, E. Smirnova, C.L. Jackson, and J.S. Bonifacino Coatomer-dependent protein delivery to lipid droplets J Cell Sci 122 2009 1834 1841
-
(2009)
J Cell Sci
, vol.122
, pp. 1834-1841
-
-
Soni, K.G.1
Mardones, G.A.2
Sougrat, R.3
Smirnova, E.4
Jackson, C.L.5
Bonifacino, J.S.6
-
198
-
-
84862828272
-
Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice
-
C. Zhang, G. Wang, Z. Zheng, K.R. Maddipati, X. Zhang, and G. Dyson et al. Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice Hepatology 55 2012 1070 1082
-
(2012)
Hepatology
, vol.55
, pp. 1070-1082
-
-
Zhang, C.1
Wang, G.2
Zheng, Z.3
Maddipati, K.R.4
Zhang, X.5
Dyson, G.6
-
199
-
-
33847618703
-
MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: Potential role of ERK in VLDL-apoB100 particle assembly
-
DOI 10.1161/01.ATV.0000249861.80471.96, PII 0004360520070100000032
-
J. Tsai, W. Qiu, R. Kohen-Avramoglu, and K. Adeli MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly Arterioscler Thromb Vasc Biol 27 2007 211 218 (Pubitemid 46360401)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.1
, pp. 211-218
-
-
Tsai, J.1
Qiu, W.2
Kohen-Avramoglu, R.3
Adeli, K.4
-
200
-
-
84865523163
-
Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia
-
J.D. Sparks, C.E. Sparks, and K. Adeli Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia Arterioscler Thromb Vasc Biol 32 2012 2104 2112
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2104-2112
-
-
Sparks, J.D.1
Sparks, C.E.2
Adeli, K.3
-
201
-
-
77953523654
-
Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression
-
H. Wang, E. Wei, A.D. Quiroga, X. Sun, N. Touret, and R. Lehner Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression Mol Biol Cell 21 2010 1991 2000
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1991-2000
-
-
Wang, H.1
Wei, E.2
Quiroga, A.D.3
Sun, X.4
Touret, N.5
Lehner, R.6
-
202
-
-
84874918522
-
Insulin-stimulated degradation of apolipoprotein B100: Roles of class II phosphatidylinositol-3-kinase and autophagy
-
U. Andreo, L. Guo, D.V. Chirieac, A.C. Tuyama, E. Montenont, and J.L. Brodsky et al. Insulin-stimulated degradation of apolipoprotein B100: roles of class II phosphatidylinositol-3-kinase and autophagy PLoS One 8 2013 e57590
-
(2013)
PLoS One
, vol.8
, pp. 57590
-
-
Andreo, U.1
Guo, L.2
Chirieac, D.V.3
Tuyama, A.C.4
Montenont, E.5
Brodsky, J.L.6
-
203
-
-
38149136598
-
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents
-
T. Ota, C. Gayet, and H.N. Ginsberg Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents J Clin Invest 118 2008 316 332
-
(2008)
J Clin Invest
, vol.118
, pp. 316-332
-
-
Ota, T.1
Gayet, C.2
Ginsberg, H.N.3
-
204
-
-
84876154662
-
Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor
-
H. Jo, S.S. Choe, K.C. Shin, H. Jang, J.H. Lee, and J.K. Seong et al. Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptor Hepatology 57 2013 1366 1377
-
(2013)
Hepatology
, vol.57
, pp. 1366-1377
-
-
Jo, H.1
Choe, S.S.2
Shin, K.C.3
Jang, H.4
Lee, J.H.5
Seong, J.K.6
-
205
-
-
84875326507
-
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets
-
F. Wilfling, H. Wang, J.T. Haas, N. Krahmer, T.J. Gould, and A. Uchida et al. Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets Dev Cell 24 2013 384 399
-
(2013)
Dev Cell
, vol.24
, pp. 384-399
-
-
Wilfling, F.1
Wang, H.2
Haas, J.T.3
Krahmer, N.4
Gould, T.J.5
Uchida, A.6
-
206
-
-
41449098953
-
Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27
-
DOI 10.1016/j.cmet.2008.03.003, PII S1550413108000740
-
K. Matsusue, T. Kusakabe, T. Noguchi, S. Takiguchi, T. Suzuki, and S. Yamano et al. Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27 Cell Metab 7 2008 302 311 (Pubitemid 351455219)
-
(2008)
Cell Metabolism
, vol.7
, Issue.4
, pp. 302-311
-
-
Matsusue, K.1
Kusakabe, T.2
Noguchi, T.3
Takiguchi, S.4
Suzuki, T.5
Yamano, S.6
Gonzalez, F.J.7
-
207
-
-
84900237792
-
The lipid droplet: A dynamic organelle, not only involved in the storage and turnover of lipids
-
C. Ehnholm, Springer-Verlag Berlin, Heidelberg
-
S.O. Olofsson, P. Bostrom, J. Lagerstedt, L. Andersson, M. Adiels, and J. Perman et al. The lipid droplet: a dynamic organelle, not only involved in the storage and turnover of lipids C. Ehnholm, Cellular lipid metabolism 2009 Springer-Verlag Berlin, Heidelberg 1 26
-
(2009)
Cellular Lipid Metabolism
, pp. 1-26
-
-
Olofsson, S.O.1
Bostrom, P.2
Lagerstedt, J.3
Andersson, L.4
Adiels, M.5
Perman, J.6
-
208
-
-
35748972649
-
SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity
-
DOI 10.1038/ncb1648, PII NCB1648
-
P. Bostrom, L. Andersson, M. Rutberg, J. Perman, U. Lidberg, and B.R. Johansson et al. SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity Nat Cell Biol 9 2007 1286 1293 (Pubitemid 350042360)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.11
, pp. 1286-1293
-
-
Bostrom, P.1
Andersson, L.2
Rutberg, M.3
Perman, J.4
Lidberg, U.5
Johansson, B.R.6
Fernandez-Rodriguez, J.7
Ericson, J.8
Nilsson, T.9
Boren, J.10
Olofsson, S.-O.11
-
209
-
-
67649470529
-
Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes
-
T. Ohya, M. Miaczynska, U. Coskun, B. Lommer, A. Runge, and D. Drechsel et al. Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes Nature 459 2009 1091 1097
-
(2009)
Nature
, vol.459
, pp. 1091-1097
-
-
Ohya, T.1
Miaczynska, M.2
Coskun, U.3
Lommer, B.4
Runge, A.5
Drechsel, D.6
-
210
-
-
24144438938
-
Cytosolic lipid droplets increase in size by microtubule-dependent complex formation
-
DOI 10.1161/01.ATV.0000179676.41064.d4
-
P. Bostrom, M. Rutberg, J. Ericsson, P. Holmdahl, L. Andersson, and M.A. Frohman et al. Cytosolic lipid droplets increase in size by microtubule- dependent complex formation Arterioscler Thromb Vasc Biol 25 2005 1945 1951 (Pubitemid 41243467)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.9
, pp. 1945-1951
-
-
Bostrom, P.1
Rutberg, M.2
Ericsson, J.3
Holmdahl, P.4
Andersson, L.5
Frohman, M.A.6
Boren, J.7
Olofsson, S.-O.8
-
211
-
-
80053609774
-
The formation of lipid droplets: Possible role in the development of insulin resistance/type 2 diabetes
-
S.O. Olofsson, L. Andersson, L. Haversen, C. Olsson, S. Myhre, and M. Rutberg et al. The formation of lipid droplets: possible role in the development of insulin resistance/type 2 diabetes Prostaglandins Leukot Essent Fatty Acids 85 2011 215 218
-
(2011)
Prostaglandins Leukot Essent Fatty Acids
, vol.85
, pp. 215-218
-
-
Olofsson, S.O.1
Andersson, L.2
Haversen, L.3
Olsson, C.4
Myhre, S.5
Rutberg, M.6
-
212
-
-
79959550724
-
Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis
-
J.W. Wu, S.P. Wang, F. Alvarez, S. Casavant, N. Gauthier, and L. Abed et al. Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis Hepatology 54 2011 122 132
-
(2011)
Hepatology
, vol.54
, pp. 122-132
-
-
Wu, J.W.1
Wang, S.P.2
Alvarez, F.3
Casavant, S.4
Gauthier, N.5
Abed, L.6
-
213
-
-
84871901684
-
Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation
-
K.T. Ong, M.T. Mashek, S.Y. Bu, and D.G. Mashek Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation FASEB J 27 2013 313 321
-
(2013)
FASEB J
, vol.27
, pp. 313-321
-
-
Ong, K.T.1
Mashek, M.T.2
Bu, S.Y.3
Mashek, D.G.4
-
214
-
-
84873178604
-
CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER- preventing diacylglycerol-mediated hepatic insulin resistance
-
J.L. Cantley, T. Yoshimura, J.P. Camporez, D. Zhang, F.R. Jornayvaz, and N. Kumashiro et al. CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance Proc Natl Acad Sci USA 110 2013 1869 1874
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1869-1874
-
-
Cantley, J.L.1
Yoshimura, T.2
Camporez, J.P.3
Zhang, D.4
Jornayvaz, F.R.5
Kumashiro, N.6
-
215
-
-
78650718129
-
Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis
-
J.N. Lee, H. Kim, H. Yao, Y. Chen, K. Weng, and J. Ye Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis Proc Natl Acad Sci USA 107 2010 21424 21429
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21424-21429
-
-
Lee, J.N.1
Kim, H.2
Yao, H.3
Chen, Y.4
Weng, K.5
Ye, J.6
-
216
-
-
33744755382
-
Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B
-
DOI 10.1091/mbc.E05-07-0659
-
Y. Ohsaki, J. Cheng, A. Fujita, T. Tokumoto, and T. Fujimoto Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B Mol Biol Cell 17 2006 2674 2683 (Pubitemid 43825504)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.6
, pp. 2674-2683
-
-
Ohsaki, Y.1
Cheng, J.2
Fujita, A.3
Tokumoto, T.4
Fujimoto, T.5
-
217
-
-
66349121084
-
Mammalian patatin domain containing proteins: A family with diverse lipolytic activities involved in multiple biological functions
-
P.C. Kienesberger, M. Oberer, A. Lass, and R. Zechner Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions J Lipid Res 50 Suppl 2009 S63 S68
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Kienesberger, P.C.1
Oberer, M.2
Lass, A.3
Zechner, R.4
-
218
-
-
77956625538
-
Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease
-
W. Chen, B. Chang, L. Li, and L. Chan Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease Hepatology 52 2010 1134 1142
-
(2010)
Hepatology
, vol.52
, pp. 1134-1142
-
-
Chen, W.1
Chang, B.2
Li, L.3
Chan, L.4
-
219
-
-
78751489992
-
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
-
M.K. Basantani, M.T. Sitnick, L. Cai, D.S. Brenner, N.P. Gardner, and J.Z. Li et al. Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome J Lipid Res 52 2011 318 329
-
(2011)
J Lipid Res
, vol.52
, pp. 318-329
-
-
Basantani, M.K.1
Sitnick, M.T.2
Cai, L.3
Brenner, D.S.4
Gardner, N.P.5
Li, J.Z.6
-
220
-
-
80054692396
-
Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: Relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance
-
A. Bartelt, P. Orlando, C. Mele, A. Ligresti, K. Toedter, and L. Scheja et al. Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance Diabetologia 54 2011 2900 2910
-
(2011)
Diabetologia
, vol.54
, pp. 2900-2910
-
-
Bartelt, A.1
Orlando, P.2
Mele, C.3
Ligresti, A.4
Toedter, K.5
Scheja, L.6
-
221
-
-
84859768059
-
Lipophagy: Connecting autophagy and lipid metabolism
-
R. Singh, and A.M. Cuervo Lipophagy: connecting autophagy and lipid metabolism Int J Cell Biol 2012 2012 282041
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 282041
-
-
Singh, R.1
Cuervo, A.M.2
-
222
-
-
84870995648
-
Regulation of lipid stores and metabolism by lipophagy
-
K. Liu, and M.J. Czaja Regulation of lipid stores and metabolism by lipophagy Cell Death Differ 20 2013 3 11
-
(2013)
Cell Death Differ
, vol.20
, pp. 3-11
-
-
Liu, K.1
Czaja, M.J.2
-
223
-
-
84873436219
-
Autophagy: Emerging roles in lipid homeostasis and metabolic control
-
P. Christian, J. Sacco, and K. Adeli Autophagy: emerging roles in lipid homeostasis and metabolic control Biochim Biophys Acta 1831 2013 819 824
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 819-824
-
-
Christian, P.1
Sacco, J.2
Adeli, K.3
-
224
-
-
41849123475
-
Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: Implications for treatment
-
DOI 10.1111/j.1572-0241.2007.01709.x
-
C. Carter-Kent, N.N. Zein, and A.E. Feldstein Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment Am J Gastroenterol 103 2008 1036 1042 (Pubitemid 351501089)
-
(2008)
American Journal of Gastroenterology
, vol.103
, Issue.4
, pp. 1036-1042
-
-
Carter-Kent, C.1
Zein, N.N.2
Feldstein, A.E.3
-
225
-
-
80052617116
-
Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression
-
Y. Inami, S. Yamashina, K. Izumi, T. Ueno, I. Tanida, and K. Ikejima et al. Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression Biochem Biophys Res Commun 412 2011 618 625
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 618-625
-
-
Inami, Y.1
Yamashina, S.2
Izumi, K.3
Ueno, T.4
Tanida, I.5
Ikejima, K.6
-
226
-
-
79952541848
-
Qushi Huayu Decoction (QHD) inhibits protein and gene expression of cathepsin B in HepG2 cells induced by free fatty acids
-
Q. Feng, Y. Cheng, Y.Y. Hu, H. Zhang, J.H. Peng, and N. Zhang Qushi Huayu Decoction (QHD) inhibits protein and gene expression of cathepsin B in HepG2 cells induced by free fatty acids Chin J Integr Med 16 2010 518 524
-
(2010)
Chin J Integr Med
, vol.16
, pp. 518-524
-
-
Feng, Q.1
Cheng, Y.2
Hu, Y.Y.3
Zhang, H.4
Peng, J.H.5
Zhang, N.6
-
227
-
-
63349104160
-
The MAP1-LC3 conjugation system is involved in lipid droplet formation
-
M. Shibata, K. Yoshimura, N. Furuya, M. Koike, T. Ueno, and M. Komatsu et al. The MAP1-LC3 conjugation system is involved in lipid droplet formation Biochem Biophys Res Commun 382 2009 419 423
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 419-423
-
-
Shibata, M.1
Yoshimura, K.2
Furuya, N.3
Koike, M.4
Ueno, T.5
Komatsu, M.6
-
228
-
-
34548150017
-
Dynamic activity of lipid droplets: Protein phosphorylation and GTP-mediated protein translocation
-
DOI 10.1021/pr070158j
-
R. Bartz, J.K. Zehmer, M. Zhu, Y. Chen, G. Serrero, and Y. Zhao et al. Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation J Proteome Res 6 2007 3256 3265 (Pubitemid 47310210)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.8
, pp. 3256-3265
-
-
Bartz, R.1
Zehmer, J.K.2
Zhu, M.3
Chen, Y.4
Serrero, G.5
Zhao, Y.6
Liu, P.7
-
229
-
-
77952954544
-
Lipid droplets: A dynamic organelle moves into focus
-
M. Beller, K. Thiel, P.J. Thul, and H. Jackle Lipid droplets: a dynamic organelle moves into focus FEBS Lett 584 2010 2176 2182
-
(2010)
FEBS Lett
, vol.584
, pp. 2176-2182
-
-
Beller, M.1
Thiel, K.2
Thul, P.J.3
Jackle, H.4
-
230
-
-
33646184680
-
ARF proteins: Roles in membrane traffic and beyond
-
C. D'Souza-Schorey, and P. Chavrier ARF proteins: roles in membrane traffic and beyond Nat Rev Mol Cell Biol 7 2006 347 358
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 347-358
-
-
D'Souza-Schorey, C.1
Chavrier, P.2
-
231
-
-
67349280293
-
Lipid droplet-organelle interactions; Sharing the fats
-
S. Murphy, S. Martin, and R.G. Parton Lipid droplet-organelle interactions; sharing the fats Biochim Biophys Acta 1791 2009 441 447
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 441-447
-
-
Murphy, S.1
Martin, S.2
Parton, R.G.3
-
232
-
-
84861423416
-
Rab5 is necessary for the biogenesis of the endolysosomal system in vivo
-
A. Zeigerer, J. Gilleron, R.L. Bogorad, G. Marsico, H. Nonaka, and S. Seifert et al. Rab5 is necessary for the biogenesis of the endolysosomal system in vivo Nature 485 2012 465 470
-
(2012)
Nature
, vol.485
, pp. 465-470
-
-
Zeigerer, A.1
Gilleron, J.2
Bogorad, R.L.3
Marsico, G.4
Nonaka, H.5
Seifert, S.6
-
233
-
-
67249150119
-
Rab7: Roles in membrane trafficking and disease
-
M. Zhang, L. Chen, S. Wang, and T. Wang Rab7: roles in membrane trafficking and disease Biosci Rep 29 2009 193 209
-
(2009)
Biosci Rep
, vol.29
, pp. 193-209
-
-
Zhang, M.1
Chen, L.2
Wang, S.3
Wang, T.4
-
234
-
-
1642602671
-
Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network
-
DOI 10.1038/ncb1090
-
C. Yeaman, M.I. Ayala, J.R. Wright, F. Bard, C. Bossard, and A. Ang et al. Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network Nat Cell Biol 6 2004 106 112 (Pubitemid 38425709)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.2
, pp. 106-112
-
-
Yeaman, C.1
Ayala, M.I.2
Wright, J.R.3
Bard, F.4
Bossard, C.5
Ang, A.6
Maeda, Y.7
Seufferlein, T.8
Mellman, I.9
Nelson, W.J.10
Malhotra, V.11
-
235
-
-
30344486984
-
Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells
-
DOI 10.1038/ncb1342, PII N1342
-
O.O. Glebov, N.A. Bright, and B.J. Nichols Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells Nat Cell Biol 8 2006 46 54 (Pubitemid 43064796)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.1
, pp. 46-54
-
-
Glebov, O.O.1
Bright, N.A.2
Nichols, B.J.3
-
236
-
-
33847755111
-
Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity
-
M.A. Tarnopolsky, C.D. Rennie, H.A. Robertshaw, S.N. Fedak-Tarnopolsky, M.C. Devries, and M.J. Hamadeh Influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure, substrate use, and mitochondrial enzyme activity Am J Physiol Regul Integr Comp Physiol 292 2007 R1271 R1278
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.292
-
-
Tarnopolsky, M.A.1
Rennie, C.D.2
Robertshaw, H.A.3
Fedak-Tarnopolsky, S.N.4
Devries, M.C.5
Hamadeh, M.J.6
-
237
-
-
84877629392
-
Mitochondria-type GPAT is required for mitochondrial fusion
-
Y. Ohba, T. Sakuragi, E. Kage-Nakadai, N.H. Tomioka, N. Kono, and R. Imae et al. Mitochondria-type GPAT is required for mitochondrial fusion EMBO J 32 2013 1265 1279
-
(2013)
EMBO J
, vol.32
, pp. 1265-1279
-
-
Ohba, Y.1
Sakuragi, T.2
Kage-Nakadai, E.3
Tomioka, N.H.4
Kono, N.5
Imae, R.6
-
238
-
-
64149132208
-
The endoplasmic reticulum enzyme DGAT2 is found in mitochondria- associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria
-
S.J. Stone, M.C. Levin, P. Zhou, J. Han, T.C. Walther, and R.V. Farese Jr. The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria J Biol Chem 284 2009 5352 5361
-
(2009)
J Biol Chem
, vol.284
, pp. 5352-5361
-
-
Stone, S.J.1
Levin, M.C.2
Zhou, P.3
Han, J.4
Walther, T.C.5
Farese, Jr.R.V.6
-
239
-
-
61549115335
-
A role for lipid droplets in inter-membrane lipid traffic
-
J.K. Zehmer, Y. Huang, G. Peng, J. Pu, R.G. Anderson, and P. Liu A role for lipid droplets in inter-membrane lipid traffic Proteomics 9 2009 914 921
-
(2009)
Proteomics
, vol.9
, pp. 914-921
-
-
Zehmer, J.K.1
Huang, Y.2
Peng, G.3
Pu, J.4
Anderson, R.G.5
Liu, P.6
-
240
-
-
2342510295
-
Role of Caveolin-1 in the Modulation of Lipolysis and Lipid Droplet Formation
-
DOI 10.2337/diabetes.53.5.1261
-
A.W. Cohen, B. Razani, W. Schubert, T.M. Williams, X.B. Wang, and P. Iyengar et al. Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation Diabetes 53 2004 1261 1270 (Pubitemid 38569012)
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1261-1270
-
-
Cohen, A.W.1
Razani, B.2
Schubert, W.3
Williams, T.M.4
Wang, X.B.5
Iyengar, P.6
Brasaemle, D.L.7
Scherer, P.E.8
Lisanti, M.P.9
-
241
-
-
84864029381
-
Genetics and molecular basis of human peroxisome biogenesis disorders
-
H.R. Waterham, and M.S. Ebberink Genetics and molecular basis of human peroxisome biogenesis disorders Biochim Biophys Acta 1822 2012 1430 1441
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 1430-1441
-
-
Waterham, H.R.1
Ebberink, M.S.2
-
243
-
-
0029069574
-
Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes
-
E.J. Blanchette-Mackie, N.K. Dwyer, T. Barber, R.A. Coxey, T. Takeda, and C.M. Rondinone et al. Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes J Lipid Res 36 1995 1211 1226
-
(1995)
J Lipid Res
, vol.36
, pp. 1211-1226
-
-
Blanchette-Mackie, E.J.1
Dwyer, N.K.2
Barber, T.3
Coxey, R.A.4
Takeda, T.5
Rondinone, C.M.6
-
244
-
-
84883612242
-
Plin2 inhibits cellular glucose uptake through interactions with SNAP23, a SNARE complex protein
-
S. Senthivinayagam, A.L. McIntosh, K.C. Moon, and B.P. Atshaves Plin2 inhibits cellular glucose uptake through interactions with SNAP23, a SNARE complex protein PLoS One 8 2013 e73696
-
(2013)
PLoS One
, vol.8
, pp. 73696
-
-
Senthivinayagam, S.1
McIntosh, A.L.2
Moon, K.C.3
Atshaves, B.P.4
-
245
-
-
35748940621
-
Lipid droplets highjack SNAREs
-
DOI 10.1038/ncb1107-1219, PII NCB1107-1219
-
T.H. Sollner Lipid droplets highjack SNAREs Nat Cell Biol 9 2007 1219 1220 (Pubitemid 350042349)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.11
, pp. 1219-1220
-
-
Sollner, T.H.1
-
246
-
-
84863989487
-
The role of pathway-selective insulin resistance and responsiveness in diabetic dyslipoproteinemia
-
X. Wu, K. Chen, and K.J. Williams The role of pathway-selective insulin resistance and responsiveness in diabetic dyslipoproteinemia Curr Opin Lipidol 23 2012 334 344
-
(2012)
Curr Opin Lipidol
, vol.23
, pp. 334-344
-
-
Wu, X.1
Chen, K.2
Williams, K.J.3
-
247
-
-
37549022688
-
Inflammation and insulin resistance
-
DOI 10.1016/j.febslet.2007.11.057, PII S0014579307012082
-
C. de Luca, and J.M. Olefsky Inflammation and insulin resistance FEBS Lett 582 2008 97 105 (Pubitemid 50010731)
-
(2008)
FEBS Letters
, vol.582
, Issue.1
, pp. 97-105
-
-
De Luca, C.1
Olefsky, J.M.2
-
248
-
-
79957889560
-
The role of lipid droplets in metabolic disease in rodents and humans
-
A.S. Greenberg, R.A. Coleman, F.B. Kraemer, J.L. McManaman, M.S. Obin, and V. Puri et al. The role of lipid droplets in metabolic disease in rodents and humans J Clin Invest 121 2011 2102 2110
-
(2011)
J Clin Invest
, vol.121
, pp. 2102-2110
-
-
Greenberg, A.S.1
Coleman, R.A.2
Kraemer, F.B.3
McManaman, J.L.4
Obin, M.S.5
Puri, V.6
-
249
-
-
80053627289
-
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
-
N. Kumashiro, D.M. Erion, D. Zhang, M. Kahn, S.A. Beddow, and X. Chu et al. Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease Proc Natl Acad Sci USA 108 2011 16381 16385
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 16381-16385
-
-
Kumashiro, N.1
Erion, D.M.2
Zhang, D.3
Kahn, M.4
Beddow, S.A.5
Chu, X.6
-
250
-
-
80052005701
-
Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice
-
A.M. Miller, H. Wang, A. Bertola, O. Park, N. Horiguchi, and S.H. Ki et al. Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice Hepatology 54 2011 846 856
-
(2011)
Hepatology
, vol.54
, pp. 846-856
-
-
Miller, A.M.1
Wang, H.2
Bertola, A.3
Park, O.4
Horiguchi, N.5
Ki, S.H.6
-
251
-
-
84873804024
-
Direct control of hepatic glucose production by interleukin-13 in mice
-
K.J. Stanya, D. Jacobi, S. Liu, P. Bhargava, L. Dai, and M.R. Gangl et al. Direct control of hepatic glucose production by interleukin-13 in mice J Clin Invest 123 2013 261 271
-
(2013)
J Clin Invest
, vol.123
, pp. 261-271
-
-
Stanya, K.J.1
Jacobi, D.2
Liu, S.3
Bhargava, P.4
Dai, L.5
Gangl, M.R.6
-
252
-
-
84864269699
-
Endoplasmic reticulum stress in nonalcoholic fatty liver disease
-
M.J. Pagliassotti Endoplasmic reticulum stress in nonalcoholic fatty liver disease Annu Rev Nutr 32 2012 17 33
-
(2012)
Annu Rev Nutr
, vol.32
, pp. 17-33
-
-
Pagliassotti, M.J.1
-
253
-
-
37349083834
-
PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-κBp65/mTOR-Dependent Mechanism
-
DOI 10.1053/j.gastro.2007.10.010, PII S0016508507018094
-
M. Vinciguerra, C. Veyrat-Durebex, M.A. Moukil, L. Rubbia-Brandt, F. Rohner-Jeanrenaud, and M. Foti PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism Gastroenterology 134 2008 268 280 (Pubitemid 350309315)
-
(2008)
Gastroenterology
, vol.134
, Issue.1
, pp. 268-280
-
-
Vinciguerra, M.1
Veyrat-Durebex, C.2
Moukil, M.A.3
Rubbia-Brandt, L.4
Rohner-Jeanrenaud, F.5
Foti, M.6
-
254
-
-
32044453080
-
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
-
DOI 10.1016/j.cell.2005.11.040, PII S0092867406000043
-
K. Zhang, X. Shen, J. Wu, K. Sakaki, T. Saunders, and D.T. Rutkowski et al. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response Cell 124 2006 587 599 (Pubitemid 43199443)
-
(2006)
Cell
, vol.124
, Issue.3
, pp. 587-599
-
-
Zhang, K.1
Shen, X.2
Wu, J.3
Sakaki, K.4
Saunders, T.5
Rutkowski, D.T.6
Back, S.H.7
Kaufman, R.J.8
-
255
-
-
80052174716
-
Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity
-
[author reply E524]
-
M. Monetti, M.C. Levin, M.J. Watt, B.K. Hubbard, C. Newgard, and R.V.S. Farese et al. Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity Proc Natl Acad Sci USA 108 2011 E523 [author reply E524]
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 523
-
-
Monetti, M.1
Levin, M.C.2
Watt, M.J.3
Hubbard, B.K.4
Newgard, C.5
Farese, R.V.S.6
-
256
-
-
79954996869
-
Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2
-
F.R. Jornayvaz, A.L. Birkenfeld, M.J. Jurczak, S. Kanda, B.A. Guigni, and D.C. Jiang et al. Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2 Proc Natl Acad Sci USA 108 2011 5748 5752
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 5748-5752
-
-
Jornayvaz, F.R.1
Birkenfeld, A.L.2
Jurczak, M.J.3
Kanda, S.4
Guigni, B.A.5
Jiang, D.C.6
-
257
-
-
84870438208
-
Effects of dietary fat energy restriction and fish oil feeding on hepatic metabolic abnormalities and insulin resistance in KK mice with high-fat diet-induced obesity
-
T. Arai, H.J. Kim, S. Hirako, M. Nakasatomi, H. Chiba, and A. Matsumoto Effects of dietary fat energy restriction and fish oil feeding on hepatic metabolic abnormalities and insulin resistance in KK mice with high-fat diet-induced obesity J Nutr Biochem 24 2013 267 273
-
(2013)
J Nutr Biochem
, vol.24
, pp. 267-273
-
-
Arai, T.1
Kim, H.J.2
Hirako, S.3
Nakasatomi, M.4
Chiba, H.5
Matsumoto, A.6
-
258
-
-
33845263672
-
Stearoyl-CoA desaturase: A new therapeutic target of liver steatosis
-
P. Dobrzyn, and A. Dobrzyn Stearoyl-CoA desaturase: a new therapeutic target of liver steatosis Drug Dev Res 67 2006 643
-
(2006)
Drug Dev Res
, vol.67
, pp. 643
-
-
Dobrzyn, P.1
Dobrzyn, A.2
-
260
-
-
78049503712
-
Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity
-
N. Sachithanandan, B.C. Fam, S. Fynch, N. Dzamko, M.J. Watt, and S. Wormald et al. Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity Hepatology 52 2010 1632 1642
-
(2010)
Hepatology
, vol.52
, pp. 1632-1642
-
-
Sachithanandan, N.1
Fam, B.C.2
Fynch, S.3
Dzamko, N.4
Watt, M.J.5
Wormald, S.6
-
261
-
-
84864665833
-
SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice
-
F. Zadjali, R. Santana-Farre, M. Vesterlund, B. Carow, M. Mirecki-Garrido, and I. Hernandez-Hernandez et al. SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice FASEB J 26 2012 3282 3291
-
(2012)
FASEB J
, vol.26
, pp. 3282-3291
-
-
Zadjali, F.1
Santana-Farre, R.2
Vesterlund, M.3
Carow, B.4
Mirecki-Garrido, M.5
Hernandez-Hernandez, I.6
-
262
-
-
84872223447
-
NF-kappaB1 deficiency stimulates the progression of non-alcoholic steatohepatitis (NASH) in mice by promoting NKT-cell-mediated responses
-
I. Locatelli, S. Sutti, M. Vacchiano, C. Bozzola, and E. Albano NF-kappaB1 deficiency stimulates the progression of non-alcoholic steatohepatitis (NASH) in mice by promoting NKT-cell-mediated responses Clin Sci (Lond) 124 2013 279 287
-
(2013)
Clin Sci (Lond)
, vol.124
, pp. 279-287
-
-
Locatelli, I.1
Sutti, S.2
Vacchiano, M.3
Bozzola, C.4
Albano, E.5
-
263
-
-
84868549057
-
Drug sensitivity and sphingolipid metabolism in CLL
-
U. Jaeger Drug sensitivity and sphingolipid metabolism in CLL Blood 120 2012 3865 3866
-
(2012)
Blood
, vol.120
, pp. 3865-3866
-
-
Jaeger, U.1
-
264
-
-
80052266598
-
Type 2 deiodinase at the crossroads of thyroid hormone action
-
E. Arrojo, R. Drigo, and A.C. Bianco Type 2 deiodinase at the crossroads of thyroid hormone action Int J Biochem Cell Biol 43 2011 1432 1441
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 1432-1441
-
-
Arrojo, E.1
Drigo, R.2
Bianco, A.C.3
-
265
-
-
84922685920
-
Novel mechanism for hepatic lipid accumulation: A physiological role for hepatic PPARgamma-fsp27 signal
-
K. Matsusue Novel mechanism for hepatic lipid accumulation: a physiological role for hepatic PPARgamma-fsp27 signal Yakugaku Zasshi 132 2012 823 829
-
(2012)
Yakugaku Zasshi
, vol.132
, pp. 823-829
-
-
Matsusue, K.1
-
266
-
-
0942287191
-
Chinese Hamster Ovary K2 Cell Lipid Droplets Appear to be Metabolic Organelles Involved in Membrane Traffic
-
DOI 10.1074/jbc.M311945200
-
P. Liu, Y. Ying, Y. Zhao, D.I. Mundy, M. Zhu, and R.G. Anderson Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic J Biol Chem 279 2004 3787 3792 (Pubitemid 38140623)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.5
, pp. 3787-3792
-
-
Liu, P.1
Ying, Y.2
Zhao, Y.3
Mundy, D.I.4
Zhu, M.5
Anderson, R.G.W.6
-
267
-
-
77951874018
-
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
-
A.J. Sanyal, N. Chalasani, K.V. Kowdley, A. McCullough, A.M. Diehl, and N.M. Bass et al. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis N Engl J Med 362 2010 1675 1685
-
(2010)
N Engl J Med
, vol.362
, pp. 1675-1685
-
-
Sanyal, A.J.1
Chalasani, N.2
Kowdley, K.V.3
McCullough, A.4
Diehl, A.M.5
Bass, N.M.6
-
268
-
-
62149086225
-
Bayesian model averaging in meta-analysis: Vitamin e supplementation and mortality
-
D. Berry, J.K. Wathen, and M. Newell Bayesian model averaging in meta-analysis: vitamin E supplementation and mortality Clin Trials 6 2009 28 41
-
(2009)
Clin Trials
, vol.6
, pp. 28-41
-
-
Berry, D.1
Wathen, J.K.2
Newell, M.3
-
269
-
-
80055028155
-
Pentoxifylline improves nonalcoholic steatohepatitis: A randomized placebo-controlled trial
-
C.O. Zein, L.M. Yerian, P. Gogate, R. Lopez, J.P. Kirwan, and A.E. Feldstein et al. Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial Hepatology 54 2011 1610 1619
-
(2011)
Hepatology
, vol.54
, pp. 1610-1619
-
-
Zein, C.O.1
Yerian, L.M.2
Gogate, P.3
Lopez, R.4
Kirwan, J.P.5
Feldstein, A.E.6
-
270
-
-
84867165316
-
Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: New evidence on the potential therapeutic mechanism
-
C.O. Zein, R. Lopez, X. Fu, J.P. Kirwan, L.M. Yerian, and A.J. McCullough et al. Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: new evidence on the potential therapeutic mechanism Hepatology 56 2012 1291 1299
-
(2012)
Hepatology
, vol.56
, pp. 1291-1299
-
-
Zein, C.O.1
Lopez, R.2
Fu, X.3
Kirwan, J.P.4
Yerian, L.M.5
McCullough, A.J.6
-
271
-
-
84886906559
-
Nonalcoholic fatty liver disease and the renin-angiotensin system: Implications for treatment
-
P. Paschos, and K. Tziomalos Nonalcoholic fatty liver disease and the renin-angiotensin system: implications for treatment World J Hepatol 4 2012 327 331
-
(2012)
World J Hepatol
, vol.4
, pp. 327-331
-
-
Paschos, P.1
Tziomalos, K.2
-
272
-
-
84878646607
-
Mitochondrial triglyceride transfer protein inhibition: New achievements in the treatment of dyslipidemias
-
M.S. Kostapanos, E.C. Rizos, N. Papanas, E. Maltezos, and M.S. Elisaf Mitochondrial triglyceride transfer protein inhibition: new achievements in the treatment of dyslipidemias Curr Pharm Des 19 2013 3150 3160
-
(2013)
Curr Pharm des
, vol.19
, pp. 3150-3160
-
-
Kostapanos, M.S.1
Rizos, E.C.2
Papanas, N.3
Maltezos, E.4
Elisaf, M.S.5
-
273
-
-
84856429876
-
Obesity, inflammation, and liver cancer
-
B. Sun, and M. Karin Obesity, inflammation, and liver cancer J Hepatol 56 2012 704 713
-
(2012)
J Hepatol
, vol.56
, pp. 704-713
-
-
Sun, B.1
Karin, M.2
-
275
-
-
84870877532
-
Functional role of monocytes and macrophages for the inflammatory response in acute liver injury
-
H.W. Zimmermann, C. Trautwein, and F. Tacke Functional role of monocytes and macrophages for the inflammatory response in acute liver injury Front Physiol 3 2012 56
-
(2012)
Front Physiol
, vol.3
, pp. 56
-
-
Zimmermann, H.W.1
Trautwein, C.2
Tacke, F.3
-
276
-
-
84861872575
-
Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2
-
K. Miura, L. Yang, N. van Rooijen, H. Ohnishi, and E. Seki Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2 Am J Physiol Gastrointest Liver Physiol 302 2012 G1310 G1321
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
-
-
Miura, K.1
Yang, L.2
Van Rooijen, N.3
Ohnishi, H.4
Seki, E.5
-
277
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
H. Kanda, S. Tateya, Y. Tamori, K. Kotani, K. Hiasa, and R. Kitazawa et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity J Clin Invest 116 2006 1494 1505
-
(2006)
J Clin Invest
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
Kitazawa, R.6
-
278
-
-
84864198388
-
A liver full of JNK: Signaling in regulation of cell function and disease pathogenesis, and clinical approaches
-
E. Seki, D.A. Brenner, and M. Karin A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches Gastroenterology 143 2012 307 320
-
(2012)
Gastroenterology
, vol.143
, pp. 307-320
-
-
Seki, E.1
Brenner, D.A.2
Karin, M.3
-
279
-
-
58149481272
-
RhoA induces expression of inflammatory cytokine in adipocytes
-
Y. Nakayama, R. Komuro, A. Yamamoto, Y. Miyata, M. Tanaka, and M. Matsuda et al. RhoA induces expression of inflammatory cytokine in adipocytes Biochem Biophys Res Commun 379 2009 288 292
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 288-292
-
-
Nakayama, Y.1
Komuro, R.2
Yamamoto, A.3
Miyata, Y.4
Tanaka, M.5
Matsuda, M.6
-
280
-
-
0035059634
-
A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats
-
DOI 10.1016/S0168-8278(00)00059-3, PII S0168827800000593
-
S. Tada, H. Iwamoto, M. Nakamuta, R. Sugimoto, M. Enjoji, and Y. Nakashima et al. A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats J Hepatol 34 2001 529 536 (Pubitemid 32328509)
-
(2001)
Journal of Hepatology
, vol.34
, Issue.4
, pp. 529-536
-
-
Tada, S.1
Iwamoto, H.2
Nakamuta, M.3
Sugimoto, R.4
Enjoji, M.5
Nakashima, Y.6
Nawata, H.7
-
281
-
-
79954452300
-
Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis
-
L. Zhao, Y. Chen, R. Tang, Y. Chen, Q. Li, and J. Gong et al. Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis J Gastroenterol Hepatol 26 2011 875 883
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 875-883
-
-
Zhao, L.1
Chen, Y.2
Tang, R.3
Chen, Y.4
Li, Q.5
Gong, J.6
-
282
-
-
84860243404
-
Inflammatory stress exacerbates hepatic cholesterol accumulation via disrupting cellular cholesterol export
-
Y. Chen, Y. Chen, L. Zhao, Y. Chen, M. Mei, and Q. Li et al. Inflammatory stress exacerbates hepatic cholesterol accumulation via disrupting cellular cholesterol export J Gastroenterol Hepatol 27 2012 974 984
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 974-984
-
-
Chen, Y.1
Chen, Y.2
Zhao, L.3
Chen, Y.4
Mei, M.5
Li, Q.6
-
283
-
-
84856297712
-
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
-
V. Bieghs, P.J. Van Gorp, K. Wouters, T. Hendrikx, M.J. Gijbels, and M. van Bilsen et al. LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease PLoS One 7 2012 e30668
-
(2012)
PLoS One
, vol.7
, pp. 30668
-
-
Bieghs, V.1
Van Gorp, P.J.2
Wouters, K.3
Hendrikx, T.4
Gijbels, M.J.5
Van Bilsen, M.6
-
284
-
-
79958229659
-
Increased production of sonic hedgehog by ballooned hepatocytes
-
F. Rangwala, C.D. Guy, J. Lu, A. Suzuki, J.L. Burchette, and M.F. Abdelmalek et al. Increased production of sonic hedgehog by ballooned hepatocytes J Pathol 224 2011 401 410
-
(2011)
J Pathol
, vol.224
, pp. 401-410
-
-
Rangwala, F.1
Guy, C.D.2
Lu, J.3
Suzuki, A.4
Burchette, J.L.5
Abdelmalek, M.F.6
-
286
-
-
84867590025
-
Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling
-
A. Pratap, S. Singh, V. Mundra, N. Yang, R. Panakanti, and J.D. Eason et al. Attenuation of early liver fibrosis by pharmacological inhibition of smoothened receptor signaling J Drug Target 20 2012 770 782
-
(2012)
J Drug Target
, vol.20
, pp. 770-782
-
-
Pratap, A.1
Singh, S.2
Mundra, V.3
Yang, N.4
Panakanti, R.5
Eason, J.D.6
-
287
-
-
4043170647
-
Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice
-
DOI 10.1002/hep.20302
-
R.S. McCuskey, Y. Ito, G.R. Robertson, M.K. McCuskey, M. Perry, and G.C. Farrell Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice Hepatology 40 2004 386 393 (Pubitemid 39062856)
-
(2004)
Hepatology
, vol.40
, Issue.2
, pp. 386-393
-
-
McCuskey, R.S.1
Ito, Y.2
Robertson, G.R.3
McCuskey, M.K.4
Perry, M.5
Farrell, G.C.6
-
288
-
-
84878626950
-
Activated hepatic stellate cells mediate the differentiation of macrophages
-
J. Chang, T. Hisamatsu, K. Shimamura, K. Yoneno, M. Adachi, and H. Naruse et al. Activated hepatic stellate cells mediate the differentiation of macrophages Hepatol Res 43 2013 658 669
-
(2013)
Hepatol Res
, vol.43
, pp. 658-669
-
-
Chang, J.1
Hisamatsu, T.2
Shimamura, K.3
Yoneno, K.4
Adachi, M.5
Naruse, H.6
-
289
-
-
43249111258
-
Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells
-
DOI 10.1007/s00535-007-2152-7
-
K. Iwamoto, K. Kanno, H. Hyogo, S. Yamagishi, M. Takeuchi, and S. Tazuma et al. Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells J Gastroenterol 43 2008 298 304 (Pubitemid 351650040)
-
(2008)
Journal of Gastroenterology
, vol.43
, Issue.4
, pp. 298-304
-
-
Iwamoto, K.1
Kanno, K.2
Hyogo, H.3
Yamagishi, S.-I.4
Takeuchi, M.5
Tazuma, S.6
Chayama, K.7
-
290
-
-
76049128362
-
Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction
-
K. Ohashi, H.K. Takahashi, S. Mori, K. Liu, H. Wake, and H. Sadamori et al. Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction Clin Immunol 134 2010 345 353
-
(2010)
Clin Immunol
, vol.134
, pp. 345-353
-
-
Ohashi, K.1
Takahashi, H.K.2
Mori, S.3
Liu, K.4
Wake, H.5
Sadamori, H.6
-
291
-
-
84857055199
-
Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury
-
C. Baeck, A. Wehr, K.R. Karlmark, F. Heymann, M. Vucur, and N. Gassler et al. Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury Gut 61 2012 416 426
-
(2012)
Gut
, vol.61
, pp. 416-426
-
-
Baeck, C.1
Wehr, A.2
Karlmark, K.R.3
Heymann, F.4
Vucur, M.5
Gassler, N.6
-
292
-
-
80054733577
-
Insulin resistance and liver microcirculation in a rat model of early NAFLD
-
M. Pasarin, J.G. Abraldes, A. Rodriguez-Vilarrupla, V. La Mura, J.C. Garcia-Pagan, and J. Bosch Insulin resistance and liver microcirculation in a rat model of early NAFLD J Hepatol 55 2011 1095 1102
-
(2011)
J Hepatol
, vol.55
, pp. 1095-1102
-
-
Pasarin, M.1
Abraldes, J.G.2
Rodriguez-Vilarrupla, A.3
La Mura, V.4
Garcia-Pagan, J.C.5
Bosch, J.6
-
293
-
-
68349146412
-
The effect of consecutively larger doses of l-arginine on hepatic microcirculation and tissue oxygenation in hepatic steatosis
-
S. Ijaz, M.C. Winslet, and A.M. Seifalian The effect of consecutively larger doses of l-arginine on hepatic microcirculation and tissue oxygenation in hepatic steatosis Microvasc Res 78 2009 206 211
-
(2009)
Microvasc Res
, vol.78
, pp. 206-211
-
-
Ijaz, S.1
Winslet, M.C.2
Seifalian, A.M.3
-
295
-
-
80455174348
-
Type of steatosis influences microcirculation and fibrogenesis in different rat strains
-
S. Rosenstengel, S. Stoeppeler, R. Bahde, H.U. Spiegel, and D. Palmes Type of steatosis influences microcirculation and fibrogenesis in different rat strains J Invest Surg 24 2011 273 282
-
(2011)
J Invest Surg
, vol.24
, pp. 273-282
-
-
Rosenstengel, S.1
Stoeppeler, S.2
Bahde, R.3
Spiegel, H.U.4
Palmes, D.5
-
296
-
-
67349205002
-
Kupffer cells in non-alcoholic fatty liver disease: The emerging view
-
G. Baffy Kupffer cells in non-alcoholic fatty liver disease: the emerging view J Hepatol 51 2009 212 223
-
(2009)
J Hepatol
, vol.51
, pp. 212-223
-
-
Baffy, G.1
-
297
-
-
84870042853
-
Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-alpha production
-
A.C. Tosello-Trampont, S.G. Landes, V. Nguyen, T.I. Novobrantseva, and Y.S. Hahn Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-alpha production J Biol Chem 287 2012 40161 40172
-
(2012)
J Biol Chem
, vol.287
, pp. 40161-40172
-
-
Tosello-Trampont, A.C.1
Landes, S.G.2
Nguyen, V.3
Novobrantseva, T.I.4
Hahn, Y.S.5
-
298
-
-
77449117735
-
Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance
-
W. Huang, A. Metlakunta, N. Dedousis, P. Zhang, I. Sipula, and J.J. Dube et al. Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance Diabetes 59 2010 347 357
-
(2010)
Diabetes
, vol.59
, pp. 347-357
-
-
Huang, W.1
Metlakunta, A.2
Dedousis, N.3
Zhang, P.4
Sipula, I.5
Dube, J.J.6
-
299
-
-
77956321989
-
The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesity
-
J. O'Connell, L. Lynch, T.J. Cawood, A. Kwasnik, N. Nolan, and J. Geoghegan et al. The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesity PLoS One 5 2010 e9997
-
(2010)
PLoS One
, vol.5
, pp. 9997
-
-
O'Connell, J.1
Lynch, L.2
Cawood, T.J.3
Kwasnik, A.4
Nolan, N.5
Geoghegan, J.6
-
300
-
-
84860419950
-
ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity
-
C. Hurtado del Pozo, G. Vesperinas-Garcia, M.A. Rubio, R. Corripio-Sanchez, A.J. Torres-Garcia, and M.J. Obregon et al. ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity Biochim Biophys Acta 1811 2011 1194 1200
-
(2011)
Biochim Biophys Acta
, vol.1811
, pp. 1194-1200
-
-
Hurtado Del Pozo, C.1
Vesperinas-Garcia, G.2
Rubio, M.A.3
Corripio-Sanchez, R.4
Torres-Garcia, A.J.5
Obregon, M.J.6
-
301
-
-
79959473762
-
O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver
-
C. Guinez, G. Filhoulaud, F. Rayah-Benhamed, S. Marmier, C. Dubuquoy, and R. Dentin et al. O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver Diabetes 60 2011 1399 1413
-
(2011)
Diabetes
, vol.60
, pp. 1399-1413
-
-
Guinez, C.1
Filhoulaud, G.2
Rayah-Benhamed, F.3
Marmier, S.4
Dubuquoy, C.5
Dentin, R.6
-
302
-
-
80052782148
-
Adiponectin suppresses endoplasmic reticulum stress in nonalcoholic steatohepatitis
-
T. Ueno, A. Nakamura, H. Nakayama, S. Otabe, X. Yuan, and T. Fukutani et al. Adiponectin suppresses endoplasmic reticulum stress in nonalcoholic steatohepatitis Exp Ther Med 2 2011 1035 1040
-
(2011)
Exp Ther Med
, vol.2
, pp. 1035-1040
-
-
Ueno, T.1
Nakamura, A.2
Nakayama, H.3
Otabe, S.4
Yuan, X.5
Fukutani, T.6
-
303
-
-
84870452496
-
Adiponectin: Key player in the adipose tissue-liver crosstalk
-
A.R. Moschen, V. Wieser, and H. Tilg Adiponectin: key player in the adipose tissue-liver crosstalk Curr Med Chem 19 2012 5467 5473
-
(2012)
Curr Med Chem
, vol.19
, pp. 5467-5473
-
-
Moschen, A.R.1
Wieser, V.2
Tilg, H.3
-
304
-
-
67650484317
-
Visceral and subcutaneous adipose tissue diacylglycerol acyltransferase activity in humans
-
X.G. Hou, S. Moser, M.G. Sarr, G.B. Thompson, F.G. Que, and M.D. Jensen Visceral and subcutaneous adipose tissue diacylglycerol acyltransferase activity in humans Obesity (Silver Spring) 17 2009 1129 1134
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1129-1134
-
-
Hou, X.G.1
Moser, S.2
Sarr, M.G.3
Thompson, G.B.4
Que, F.G.5
Jensen, M.D.6
-
305
-
-
79953297691
-
DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes
-
C.A. Harris, J.T. Haas, R.S. Streeper, S.J. Stone, M. Kumari, and K. Yang et al. DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes J Lipid Res 52 2011 657 667
-
(2011)
J Lipid Res
, vol.52
, pp. 657-667
-
-
Harris, C.A.1
Haas, J.T.2
Streeper, R.S.3
Stone, S.J.4
Kumari, M.5
Yang, K.6
-
306
-
-
12344332455
-
Cytokines and the pathogenesis of non-alcoholic steatohepatitis
-
DOI 10.1136/gut.2003.024935
-
A.M. Diehl, Z.P. Li, H.Z. Lin, and S.Q. Yang Cytokines and the pathogenesis of non-alcoholic steatohepatitis Gut 54 2005 303 306 (Pubitemid 40139250)
-
(2005)
Gut
, vol.54
, Issue.2
, pp. 303-306
-
-
Diehl, A.M.1
Li, Z.P.2
Lin, H.Z.3
Yang, S.Q.4
-
307
-
-
84862500687
-
Hepatic steatosis in type 1 diabetes
-
S.E. Regnell, and A. Lernmark Hepatic steatosis in type 1 diabetes Rev Diabet Stud 8 2011 454 467
-
(2011)
Rev Diabet Stud
, vol.8
, pp. 454-467
-
-
Regnell, S.E.1
Lernmark, A.2
-
308
-
-
79960555502
-
Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo
-
S. Wang, A. Kamat, P. Pergola, A. Swamy, F. Tio, and K. Cusi Metabolic factors in the development of hepatic steatosis and altered mitochondrial gene expression in vivo Metabolism 60 2011 1090 1099
-
(2011)
Metabolism
, vol.60
, pp. 1090-1099
-
-
Wang, S.1
Kamat, A.2
Pergola, P.3
Swamy, A.4
Tio, F.5
Cusi, K.6
-
309
-
-
34547681197
-
Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes
-
DOI 10.1007/s00125-007-0739-4
-
H.A. Jamieson, V.C. Cogger, S.M. Twigg, S.V. McLennan, A. Warren, and R. Cheluvappa et al. Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes Diabetologia 50 2007 1969 1976 (Pubitemid 47222858)
-
(2007)
Diabetologia
, vol.50
, Issue.9
, pp. 1969-1976
-
-
Jamieson, H.A.1
Cogger, V.C.2
Twigg, S.M.3
McLennan, S.V.4
Warren, A.5
Cheluvappa, R.6
Hilmer, S.N.7
Fraser, R.8
De Cabo, R.9
Le Couteur, D.G.10
-
310
-
-
80455125921
-
Unmasking differential effects of rosiglitazone and pioglitazone in the combination treatment with n-3 fatty acids in mice fed a high-fat diet
-
V. Kus, P. Flachs, O. Kuda, K. Bardova, P. Janovska, and M. Svobodova et al. Unmasking differential effects of rosiglitazone and pioglitazone in the combination treatment with n-3 fatty acids in mice fed a high-fat diet PLoS One 6 2011 e27126
-
(2011)
PLoS One
, vol.6
, pp. 27126
-
-
Kus, V.1
Flachs, P.2
Kuda, O.3
Bardova, K.4
Janovska, P.5
Svobodova, M.6
-
311
-
-
83555164835
-
Meta-analysis: Pioglitazone improves liver histology and fibrosis in patients with non-alcoholic steatohepatitis
-
E. Boettcher, G. Csako, F. Pucino, R. Wesley, and R. Loomba Meta-analysis: pioglitazone improves liver histology and fibrosis in patients with non-alcoholic steatohepatitis Aliment Pharmacol Ther 35 2012 66 75
-
(2012)
Aliment Pharmacol Ther
, vol.35
, pp. 66-75
-
-
Boettcher, E.1
Csako, G.2
Pucino, F.3
Wesley, R.4
Loomba, R.5
-
312
-
-
84862300888
-
Nonalcoholic fatty liver disease and vascular risk
-
L.S. Bhatia, N.P. Curzen, and C.D. Byrne Nonalcoholic fatty liver disease and vascular risk Curr Opin Cardiol 27 2012 420 428
-
(2012)
Curr Opin Cardiol
, vol.27
, pp. 420-428
-
-
Bhatia, L.S.1
Curzen, N.P.2
Byrne, C.D.3
-
313
-
-
84861417701
-
Non-alcoholic fatty liver disease: A new and important cardiovascular risk factor?
-
L.S. Bhatia, N.P. Curzen, P.C. Calder, and C.D. Byrne Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor? Eur Heart J 33 2012 1190 1200
-
(2012)
Eur Heart J
, vol.33
, pp. 1190-1200
-
-
Bhatia, L.S.1
Curzen, N.P.2
Calder, P.C.3
Byrne, C.D.4
-
314
-
-
0038369154
-
Low adiponectin levels in adolescent obesity: A marker of increased intramyocellular lipid accumulation
-
DOI 10.1210/jc.2002-021711
-
R. Weiss, S. Dufour, A. Groszmann, K. Petersen, J. Dziura, and S.E. Taksali et al. Low adiponectin levels in adolescent obesity: a marker of increased intramyocellular lipid accumulation J Clin Endocrinol Metab 88 2003 2014 2018 (Pubitemid 36549870)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.5
, pp. 2014-2018
-
-
Weiss, R.1
Dufour, S.2
Groszmann, A.3
Petersen, K.4
Dziura, J.5
Taksali, S.E.6
Shulman, G.7
Caprio, S.8
-
315
-
-
84877854022
-
Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease
-
M. Gaggini, M. Morelli, E. Buzzigoli, R.A. DeFronzo, E. Bugianesi, and A. Gastaldelli Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease Nutrients 5 2013 1544 1560
-
(2013)
Nutrients
, vol.5
, pp. 1544-1560
-
-
Gaggini, M.1
Morelli, M.2
Buzzigoli, E.3
Defronzo, R.A.4
Bugianesi, E.5
Gastaldelli, A.6
-
316
-
-
84896943116
-
Primary hepatocellular carcinoma and metabolic syndrome: An update
-
R. Rahman, G.M. Hammoud, A.A. Almashhrawi, K.T. Ahmed, and J.A. Ibdah Primary hepatocellular carcinoma and metabolic syndrome: an update World J Gastrointest Oncol 5 2013 186 194
-
(2013)
World J Gastrointest Oncol
, vol.5
, pp. 186-194
-
-
Rahman, R.1
Hammoud, G.M.2
Almashhrawi, A.A.3
Ahmed, K.T.4
Ibdah, J.A.5
-
317
-
-
79958148945
-
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management
-
M.J. Chapman, H.N. Ginsberg, P. Amarenco, F. Andreotti, J. Boren, and A.L. Catapano et al. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management Eur Heart J 32 2011 1345 1361
-
(2011)
Eur Heart J
, vol.32
, pp. 1345-1361
-
-
Chapman, M.J.1
Ginsberg, H.N.2
Amarenco, P.3
Andreotti, F.4
Boren, J.5
Catapano, A.L.6
-
318
-
-
84855171923
-
Diagnosis and evaluation of nonalcoholic fatty liver disease
-
M. Obika, and H. Noguchi Diagnosis and evaluation of nonalcoholic fatty liver disease Exp Diabetes Res 2012 2012 145754
-
(2012)
Exp Diabetes Res
, vol.2012
, pp. 145754
-
-
Obika, M.1
Noguchi, H.2
-
319
-
-
84888870308
-
A novel noninvasive index for nonalcoholic steatohepatitis: A pilot study
-
S.A. Polyzos, J. Kountouras, A. Slavakis, E. Zafeiriadou, K. Patsiaoura, and E. Katsiki et al. A novel noninvasive index for nonalcoholic steatohepatitis: a pilot study Biomarkers 2013
-
(2013)
Biomarkers
-
-
Polyzos, S.A.1
Kountouras, J.2
Slavakis, A.3
Zafeiriadou, E.4
Patsiaoura, K.5
Katsiki, E.6
-
320
-
-
84885124263
-
Diagnosing Fatty liver disease: A comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers
-
S. Siegert, Z. Yu, R. Wang-Sattler, T. Illig, J. Adamski, and J. Hampe et al. Diagnosing Fatty liver disease: a comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers PLoS One 8 2013 e76813
-
(2013)
PLoS One
, vol.8
, pp. 76813
-
-
Siegert, S.1
Yu, Z.2
Wang-Sattler, R.3
Illig, T.4
Adamski, J.5
Hampe, J.6
-
321
-
-
78149477200
-
Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice
-
J.S. Yang, J.T. Kim, J. Jeon, H.S. Park, G.H. Kang, and K.S. Park et al. Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice PLoS One 5 2010 e13858
-
(2010)
PLoS One
, vol.5
, pp. 13858
-
-
Yang, J.S.1
Kim, J.T.2
Jeon, J.3
Park, H.S.4
Kang, G.H.5
Park, K.S.6
-
322
-
-
78649878256
-
Exenatide in the treatment of diabetic patients with non-alcoholic steatohepatitis: A case series
-
P.R. Kenny, D.E. Brady, D.M. Torres, L. Ragozzino, N. Chalasani, and S.A. Harrison Exenatide in the treatment of diabetic patients with non-alcoholic steatohepatitis: a case series Am J Gastroenterol 105 2010 2707 2709
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 2707-2709
-
-
Kenny, P.R.1
Brady, D.E.2
Torres, D.M.3
Ragozzino, L.4
Chalasani, N.5
Harrison, S.A.6
-
323
-
-
83455201680
-
Effect of spironolactone and vitamin e on serum metabolic parameters and insulin resistance in patients with nonalcoholic fatty liver disease
-
S.A. Polyzos, J. Kountouras, E. Zafeiriadou, K. Patsiaoura, E. Katsiki, and G. Deretzi et al. Effect of spironolactone and vitamin E on serum metabolic parameters and insulin resistance in patients with nonalcoholic fatty liver disease J Renin Angiotensin Aldosterone Syst 12 2011 498 503
-
(2011)
J Renin Angiotensin Aldosterone Syst
, vol.12
, pp. 498-503
-
-
Polyzos, S.A.1
Kountouras, J.2
Zafeiriadou, E.3
Patsiaoura, K.4
Katsiki, E.5
Deretzi, G.6
-
324
-
-
78650969341
-
Effect of atorvastatin, vitamin e and C on nonalcoholic fatty liver disease: Is the combination required?
-
B.M. Arendt, and J.P. Allard Effect of atorvastatin, vitamin E and C on nonalcoholic fatty liver disease: is the combination required? Am J Gastroenterol 106 2011 78 80
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 78-80
-
-
Arendt, B.M.1
Allard, J.P.2
-
325
-
-
33747622293
-
SNAREs - Engines for membrane fusion
-
DOI 10.1038/nrm2002, PII NRM2002
-
R. Jahn, and R.H. Scheller SNAREs - engines for membrane fusion Nat Rev Mol Cell Biol 7 2006 631 643 (Pubitemid 44268209)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.9
, pp. 631-643
-
-
Jahn, R.1
Scheller, R.H.2
|