Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production

Journal of Biological Chemistry

Volumn 287, Issue 48, 2012, Pages 40161-40172

  Tosello Trampont, Annie Carole ^a   Landes, Susan G ^a   Nguyen, Virginia ^a   Novobrantseva, Tatiana I ^c   Hahn, Young S ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c ALNYLAM PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD MONOCYTES; CHEMOKINES; DIFFERENTIAL CONTRIBUTION; HEPATIC DAMAGE; HEPATIC INJURY; HEPATOCARCINOMA; HEPATOCYTES; KUPFFER CELLS; LIVER DAMAGE; LIVER INJURIES; MOUSE MODELS; MURINE MODEL; MYELOID CELLS; NON-ALCOHOLIC STEATOHEPATITIS; PATHOGENIC MECHANISMS; PROINFLAMMATORY; TUMOR NECROSIS FACTORS;

AMINO ACIDS; BLOOD; MACROPHAGES; NUTRITION; PATHOLOGY;

LIVER;

CD11B ANTIGEN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; FATTY LIVER; FEMALE; GENE SILENCING; HEPATITIS; KUPFFER CELL; LIPID STORAGE; MONOCYTE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; CHEMOKINE CCL2; CHEMOKINE CXCL10; CHOLINE; DIET; DISEASE MODELS, ANIMAL; FATTY LIVER; FEMALE; HUMANS; KUPFFER CELLS; METHIONINE; MICE; MICE, INBRED C57BL; MONOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE;

EID: 84870042853     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.417014     Document Type: Article

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