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Volumn 19, Issue 32, 2012, Pages 5467-5473

Adiponectin: Key player in the adipose tissue-liver crosstalk

Author keywords

Adipocytokines; Cytokines; Inflammation; Insulin resistance; Non alcoholic fatty liver disease

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEME OXYGENASE 1; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; SHORT HAIRPIN RNA; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA;

EID: 84870452496     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712803833254     Document Type: Article
Times cited : (74)

References (95)
  • 1
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer, P. E.; Williams, S.; Fogliano, M.; Baldini, G.; Lodish, H. F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J. Biol. Chem., 1995, 270(45), 26746-26749.
    • (1995) J. Biol. Chem. , vol.270 , Issue.45 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 2
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
    • Tilg, H.; Moschen, A. R. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat.Rev.Immunol., 2006, 6(10), 772-783.
    • (2006) Nat.Rev.Immunol. , vol.6 , Issue.10 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 3
    • 32444448856 scopus 로고    scopus 로고
    • Up-regulation of the anti-inflammatory adipokine adiponectin in acute liver failure in mice
    • Wolf, A. M.; Wolf, D.; Avila, M. A.; Moschen, A. R.; Berasain, C.; Enrich, B.; Rumpold, H.; Tilg, H. Up-regulation of the anti-inflammatory adipokine adiponectin in acute liver failure in mice. J.Hepatol., 2006, 44(3), 537-543.
    • (2006) J.Hepatol. , vol.44 , Issue.3 , pp. 537-543
    • Wolf, A.M.1    Wolf, D.2    Avila, M.A.3    Moschen, A.R.4    Berasain, C.5    Enrich, B.6    Rumpold, H.7    Tilg, H.8
  • 5
    • 9444285912 scopus 로고    scopus 로고
    • Induction of adiponectin in skeletal muscle by inflammatory cytokines: In vivo and in vitro studies
    • Delaigle, A. M.; Jonas, J. C.; Bauche, I. B.; Cornu, O.; Brichard, S. M. Induction of adiponectin in skeletal muscle by inflammatory cytokines: in vivo and in vitro studies. Endocrinology, 2004, 145(12), 5589-5597.
    • (2004) Endocrinology , vol.145 , Issue.12 , pp. 5589-5597
    • Delaigle, A.M.1    Jonas, J.C.2    Bauche, I.B.3    Cornu, O.4    Brichard, S.M.5
  • 6
    • 77953356804 scopus 로고    scopus 로고
    • Gluttony, sloth and the metabolic syndrome: A roadmap to lipotoxicity
    • Unger, R. H.; Scherer, P. E. Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity. Trends Endocrinol. Metab., 2010, 21(6), 345-352.
    • (2010) Trends Endocrinol. Metab. , vol.21 , Issue.6 , pp. 345-352
    • Unger, R.H.1    Scherer, P.E.2
  • 7
    • 79957916782 scopus 로고    scopus 로고
    • Adipose tissue remodeling and obesity
    • Sun, K.; Kusminski, C. M.; Scherer, P. E. Adipose tissue remodeling and obesity. J. Clin. Invest., 2011, 121(6), 2094-2101.
    • (2011) J. Clin. Invest. , vol.121 , Issue.6 , pp. 2094-2101
    • Sun, K.1    Kusminski, C.M.2    Scherer, P.E.3
  • 9
    • 55649103668 scopus 로고    scopus 로고
    • Insulin resistance, inflammation, and non-alcoholic fatty liver disease
    • Tilg, H.; Moschen, A. R. Insulin resistance, inflammation, and non-alcoholic fatty liver disease. Trends Endocrinol. Metab, 2008, 19(10), 371-379.
    • (2008) Trends Endocrinol. Metab , vol.19 , Issue.10 , pp. 371-379
    • Tilg, H.1    Moschen, A.R.2
  • 12
    • 0036154816 scopus 로고    scopus 로고
    • NASH: From liver diseases to metabolic disorders and back to clinical hepatology
    • Marchesini, G.; Forlani, G. NASH: from liver diseases to metabolic disorders and back to clinical hepatology. Hepatology, 2002, 35(2), 497-499.
    • (2002) Hepatology , vol.35 , Issue.2 , pp. 497-499
    • Marchesini, G.1    Forlani, G.2
  • 13
    • 79954548597 scopus 로고    scopus 로고
    • Insulin resistance in nonalcoholic steatohepatitis: Necessary but not sufficient - Death of a dogma from analysis of therapeutic studies?
    • Lonardo, A.; Bellentani, S.; Ratziu, V.; Loria, P. Insulin resistance in nonalcoholic steatohepatitis: necessary but not sufficient - death of a dogma from analysis of therapeutic studies? Expert Rev. Gastroenterol. Hepatol., 2011, 5(2), 279-289.
    • (2011) Expert Rev. Gastroenterol. Hepatol. , vol.5 , Issue.2 , pp. 279-289
    • Lonardo, A.1    Bellentani, S.2    Ratziu, V.3    Loria, P.4
  • 16
    • 0034284038 scopus 로고    scopus 로고
    • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
    • Yokota, T.; Oritani, K.; Takahashi, I.; Ishikawa, J.; Matsuyama, A.; Ouchi, N.; Kihara, S.; Funahashi, T.; Tenner, A. J.; Tomiyama, Y.; Matsuzawa, Y. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood, 2000, 96(5), 1723-1732.
    • (2000) Blood , vol.96 , Issue.5 , pp. 1723-1732
    • Yokota, T.1    Oritani, K.2    Takahashi, I.3    Ishikawa, J.4    Matsuyama, A.5    Ouchi, N.6    Kihara, S.7    Funahashi, T.8    Tenner, A.J.9    Tomiyama, Y.10    Matsuzawa, Y.11
  • 18
    • 4544334655 scopus 로고    scopus 로고
    • Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes
    • Wolf, A. M.; Wolf, D.; Rumpold, H.; Enrich, B.; Tilg, H. Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes. Biochem. Biophys. Res. Commun., 2004, 323(2), 630-635.
    • (2004) Biochem. Biophys. Res. Commun. , vol.323 , Issue.2 , pp. 630-635
    • Wolf, A.M.1    Wolf, D.2    Rumpold, H.3    Enrich, B.4    Tilg, H.5
  • 19
    • 77950625277 scopus 로고    scopus 로고
    • The antiinflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells
    • Mandal, P.; Park, P. H.; McMullen, M. R.; Pratt, B. T.; Nagy, L. E. The antiinflammatory effects of adiponectin are mediated via a heme oxygenase-1-dependent pathway in rat Kupffer cells. Hepatology, 2010, 51(4), 1420-1429.
    • (2010) Hepatology , vol.51 , Issue.4 , pp. 1420-1429
    • Mandal, P.1    Park, P.H.2    McMullen, M.R.3    Pratt, B.T.4    Nagy, L.E.5
  • 20
    • 77957377563 scopus 로고    scopus 로고
    • Adiponectin-mediated heme oxygenase-1 induction protects against ironinduced liver injury via a PPARalpha dependent mechanism
    • Lin, H.; Yu, C. H.; Jen, C. Y.; Cheng, C. F.; Chou, Y.; Chang, C. C.; Juan, S. H. Adiponectin-mediated heme oxygenase-1 induction protects against ironinduced liver injury via a PPARalpha dependent mechanism. Am. J. Pathol., 2010, 177(4), 1697-1709.
    • (2010) Am. J. Pathol. , vol.177 , Issue.4 , pp. 1697-1709
    • Lin, H.1    Yu, C.H.2    Jen, C.Y.3    Cheng, C.F.4    Chou, Y.5    Chang, C.C.6    Juan, S.H.7
  • 21
    • 78049492112 scopus 로고    scopus 로고
    • Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure
    • Mandal, P.; Roychowdhury, S.; Park, P. H.; Pratt, B. T.; Roger, T.; Nagy, L. E. Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure. J. Immunol., 2010, 185(8), 4928-4937.
    • (2010) J. Immunol. , vol.185 , Issue.8 , pp. 4928-4937
    • Mandal, P.1    Roychowdhury, S.2    Park, P.H.3    Pratt, B.T.4    Roger, T.5    Nagy, L.E.6
  • 23
    • 77956114717 scopus 로고    scopus 로고
    • Anti-inflammatory effects of excessive Weight loss: Potent suppression of adipose interleukin-6 and tumour necrosis factor-alpha expression
    • Moschen, A. R.; Molnar, C.; Geiger, S.; Graziadei, I.; Ebenbichler, C. F.; Weiss, H.; Kaser, S.; Kaser, A.; Tilg, H. Anti-inflammatory effects of excessive Weight loss: potent suppression of adipose interleukin-6 and tumour necrosis factor-alpha expression. Gut, 2010, 59, 1259-1264.
    • (2010) Gut , vol.59 , pp. 1259-1264
    • Moschen, A.R.1    Molnar, C.2    Geiger, S.3    Graziadei, I.4    Ebenbichler, C.F.5    Weiss, H.6    Kaser, S.7    Kaser, A.8    Tilg, H.9
  • 24
    • 0037677767 scopus 로고    scopus 로고
    • Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors
    • Iwaki, M.; Matsuda, M.; Maeda, N.; Funahashi, T.; Matsuzawa, Y.; Makishima, M.; Shimomura, I. Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes, 2003, 52(7), 1655-1663.
    • (2003) Diabetes , vol.52 , Issue.7 , pp. 1655-1663
    • Iwaki, M.1    Matsuda, M.2    Maeda, N.3    Funahashi, T.4    Matsuzawa, Y.5    Makishima, M.6    Shimomura, I.7
  • 25
    • 9144229185 scopus 로고    scopus 로고
    • Adipose-specific peroxisome proliferatoractivated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle
    • He, W.; Barak, Y.; Hevener, A.; Olson, P.; Liao, D.; Le, J.; Nelson, M.; Ong, E.; Olefsky, J. M.; Evans, R. M. Adipose-specific peroxisome proliferatoractivated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc. Natl. Acad. Sci. U.S.A, 2003, 100(26), 15712-15717.
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , Issue.26 , pp. 15712-15717
    • He, W.1    Barak, Y.2    Hevener, A.3    Olson, P.4    Le Liao, D.J.5    Nelson, M.6    Ong, E.7    Olefsky, J.M.8    Evans, R.M.9
  • 33
    • 77958570952 scopus 로고    scopus 로고
    • Alcohol drinking status is associated with serum high molecular weight adiponectin in community-dwelling Japanese men
    • Kawamoto, R.; Tabara, Y.; Kohara, K.; Miki, T.; Ohtsuka, N.; Kusunoki, T.; Abe, M. Alcohol drinking status is associated with serum high molecular weight adiponectin in community-dwelling Japanese men. J. Atheroscler. Thromb., 2010, 17(9), 953-962.
    • (2010) J. Atheroscler. Thromb. , vol.17 , Issue.9 , pp. 953-962
    • Kawamoto, R.1    Tabara, Y.2    Kohara, K.3    Miki, T.4    Ohtsuka, N.5    Kusunoki, T.6    Abe, M.7
  • 34
    • 79951810722 scopus 로고    scopus 로고
    • Serum total adiponectin in nonalcoholic fatty liver disease: A systematic review and meta-analysis
    • Polyzos, S. A.; Toulis, K. A.; Goulis, D. G.; Zavos, C.; Kountouras, J. Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis. Metabolism, 2011, 60(3), 313-326.
    • (2011) Metabolism , vol.60 , Issue.3 , pp. 313-326
    • Polyzos, S.A.1    Toulis, K.A.2    Goulis, D.G.3    Zavos, C.4    Kountouras, J.5
  • 35
    • 78649950656 scopus 로고    scopus 로고
    • Adiponectin isoforms, insulin resistance and liver histology in nonalcoholic fatty liver disease
    • Bianchi, G.; Bugianesi, E.; Frystyk, J.; Tarnow, L.; Flyvbjerg, A.; Marchesini, G. Adiponectin isoforms, insulin resistance and liver histology in nonalcoholic fatty liver disease. Dig. Liver Dis., 2011, 43(1), 73-77.
    • (2011) Dig. Liver Dis. , vol.43 , Issue.1 , pp. 73-77
    • Bianchi, G.1    Bugianesi, E.2    Frystyk, J.3    Tarnow, L.4    Flyvbjerg, A.5    Marchesini, G.6
  • 38
    • 79952207246 scopus 로고    scopus 로고
    • Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver disease
    • Ayonrinde, O. T.; Olynyk, J. K.; Beilin, L. J.; Mori, T. A.; Pennell, C. E.; de Klerk, N.; Oddy, W. H.; Shipman, P.; Adams, L. A. Gender-specific differences in adipose distribution and adipocytokines influence adolescent nonalcoholic fatty liver disease. Hepatology, 2011, 53(3), 800-809.
    • (2011) Hepatology , vol.53 , Issue.3 , pp. 800-809
    • Ayonrinde, O.T.1    Olynyk, J.K.2    Beilin, L.J.3    Mori, T.A.4    Pennell, C.E.5    De Klerk, N.6    Oddy, W.H.7    Shipman, P.8    Adams, L.A.9
  • 39
    • 0036125944 scopus 로고    scopus 로고
    • Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes
    • Hirose, H.; Kawai, T.; Yamamoto, Y.; Taniyama, M.; Tomita, M.; Matsubara, K.; Okazaki, Y.; Ishii, T.; Oguma, Y.; Takei, I.; Saruta, T. Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes. Metabolism., 2002, 51(3), 314-317.
    • (2002) Metabolism. , vol.51 , Issue.3 , pp. 314-317
    • Hirose, H.1    Kawai, T.2    Yamamoto, Y.3    Taniyama, M.4    Tomita, M.5    Matsubara, K.6    Okazaki, Y.7    Ishii, T.8    Oguma, Y.9    Takei, I.10    Saruta, T.11
  • 40
    • 33746340885 scopus 로고    scopus 로고
    • Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: Relationship to histological improvement
    • Lutchman, G.; Promrat, K.; Kleiner, D. E.; Heller, T.; Ghany, M. G.; Yanovski, J. A.; Liang, T. J.; Hoofnagle, J. H. Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement. Clin. Gastroenterol. Hepatol., 2006, 4(8), 1048-1052.
    • (2006) Clin. Gastroenterol. Hepatol. , vol.4 , Issue.8 , pp. 1048-1052
    • Lutchman, G.1    Promrat, K.2    Kleiner, D.E.3    Heller, T.4    Ghany, M.G.5    Yanovski, J.A.6    Liang, T.J.7    Hoofnagle, J.H.8
  • 41
    • 70350043699 scopus 로고    scopus 로고
    • Effects of ursodeoxycholic acid in combination with vitamin e on adipokines and apoptosis in patients with nonalcoholic steatohepatitis
    • Balmer, M. L.; Siegrist, K.; Zimmermann, A.; Dufour, J. F. Effects of ursodeoxycholic acid in combination with vitamin E on adipokines and apoptosis in patients with nonalcoholic steatohepatitis. Liver Int., 2009, 29(8), 1184-1188.
    • (2009) Liver Int. , vol.29 , Issue.8 , pp. 1184-1188
    • Balmer, M.L.1    Siegrist, K.2    Zimmermann, A.3    Dufour, J.F.4
  • 43
    • 79955650290 scopus 로고    scopus 로고
    • Up-regulation of PPAR-gamma mRNA expression in the liver of obese patients: An additional reinforcing lipogenic mechanism to SREBP-1c induction
    • Pettinelli, P.; Videla, L. A. Up-regulation of PPAR-gamma mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c induction. J. Clin. Endocrinol. Metab., 2011, 96(5), 1424-1430.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , Issue.5 , pp. 1424-1430
    • Pettinelli, P.1    Videla, L.A.2
  • 44
    • 71549135671 scopus 로고    scopus 로고
    • Adiponectin expression is induced by vitamin e via a peroxisome proliferator-activated receptor gamma-dependent mechanism
    • Landrier, J. F.; Gouranton, E.; El Yazidi, C.; Malezet, C.; Balaguer, P.; Borel, P.; Amiot, M. J. Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. Endocrinology, 2009, 150(12), 5318-5325.
    • (2009) Endocrinology , vol.150 , Issue.12 , pp. 5318-5325
    • Landrier, J.F.1    Gouranton, E.2    El Yazidi, C.3    Malezet, C.4    Balaguer, P.5    Borel, P.6    Amiot, M.J.7
  • 46
    • 80051791560 scopus 로고    scopus 로고
    • Treatment with insulin sensitizer metformin improves arterial properties, metabolic parameters, and liver function in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial
    • Sofer, E.; Boaz, M.; Matas, Z.; Mashavi, M.; Shargorodsky, M. Treatment with insulin sensitizer metformin improves arterial properties, metabolic parameters, and liver function in patients with nonalcoholic fatty liver disease: a randomized, placebo-controlled trial. Metabolism, 2011, 60(9), 1278-1284.
    • (2011) Metabolism , vol.60 , Issue.9 , pp. 1278-1284
    • Sofer, E.1    Boaz, M.2    Matas, Z.3    Mashavi, M.4    Shargorodsky, M.5
  • 49
    • 48449096011 scopus 로고    scopus 로고
    • MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes
    • Larter, C. Z.; Yeh, M. M.; Williams, J.; Bell-Anderson, K. S.; Farrell, G. C. MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes. J. Hepatol., 2008, 49(3), 407-416.
    • (2008) J. Hepatol. , vol.49 , Issue.3 , pp. 407-416
    • Larter, C.Z.1    Yeh, M.M.2    Williams, J.3    Bell-Anderson, K.S.4    Farrell, G.C.5
  • 50
    • 78649741621 scopus 로고    scopus 로고
    • The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats
    • Liu, S.; Wu, H. J.; Zhang, Z. Q.; Chen, Q.; Liu, B.; Wu, J. P.; Zhu, L. The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats. Eur. J. Pharmacol., 2011, 650(1), 384-389.
    • (2011) Eur. J. Pharmacol. , vol.650 , Issue.1 , pp. 384-389
    • Liu, S.1    Wu, H.J.2    Zhang, Z.Q.3    Chen, Q.4    Liu, B.5    Wu, J.P.6    Zhu, L.7
  • 51
    • 77249094005 scopus 로고    scopus 로고
    • Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice
    • Shen, Z.; Liang, X.; Rogers, C. Q.; Rideout, D.; You, M. Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice. Am. J. Physiol. Gastrointest. Liver Physiol., 2010, 298(3), G364-374.
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.298 , Issue.3
    • Shen, Z.1    Liang, X.2    Rogers, C.Q.3    Rideout, D.4    You, M.5
  • 57
    • 34547444610 scopus 로고    scopus 로고
    • Insulin resistance and liver injury in hepatitis C is not associated with virus-specific changes in adipocytokines
    • Cua, I. H.; Hui, J. M.; Bandara, P.; Kench, J. G.; Farrell, G. C.; McCaughan, G. W.; George, J. Insulin resistance and liver injury in hepatitis C is not associated with virus-specific changes in adipocytokines. Hepatology, 2007, 46(1), 66-73.
    • (2007) Hepatology , vol.46 , Issue.1 , pp. 66-73
    • Cua, I.H.1    Hui, J.M.2    Bandara, P.3    Kench, J.G.4    Farrell, G.C.5    McCaughan, G.W.6    George, J.7
  • 58
    • 49649100199 scopus 로고    scopus 로고
    • A novel role for adiponectin in regulating the immune responses in chronic hepatitis C virus infection
    • Palmer, C.; Hampartzoumian, T.; Lloyd, A.; Zekry, A. A novel role for adiponectin in regulating the immune responses in chronic hepatitis C virus infection. Hepatology, 2008, 48(2), 374-384.
    • (2008) Hepatology , vol.48 , Issue.2 , pp. 374-384
    • Palmer, C.1    Hampartzoumian, T.2    Lloyd, A.3    Zekry, A.4
  • 61
    • 84984573501 scopus 로고    scopus 로고
    • High serum adiponectin correlates with advanced liver disease in patients with chronic hepatitis B virus infection
    • Liu, C. J.; Chen, P. J.; Lai, M. Y.; Liu, C. H.; Chen, C. L.; Kao, J. H.; Chen, D. S. High serum adiponectin correlates with advanced liver disease in patients with chronic hepatitis B virus infection. Hepatol. Int., 2009, 3(2), 364-370.
    • (2009) Hepatol. Int. , vol.3 , Issue.2 , pp. 364-370
    • Liu, C.J.1    Chen, P.J.2    Lai, M.Y.3    Liu, C.H.4    Chen, C.L.5    Kao, J.H.6    Chen, D.S.7
  • 65
    • 3042744039 scopus 로고    scopus 로고
    • Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemodynamics
    • Tietge, U. J.; Boker, K. H.; Manns, M. P.; Bahr, M. J. Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemodynamics. Am. J. Physiol. Endocrinol. Metab., 2004, 287(1), E82-E89.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.287 , Issue.1
    • Tietge, U.J.1    Boker, K.H.2    Manns, M.P.3    Bahr, M.J.4
  • 68
    • 77956395742 scopus 로고    scopus 로고
    • Significance of serum adiponectin levels in patients with chronic liver disease
    • Balmer, M. L.; Joneli, J.; Schoepfer, A.; Stickel, F.; Thormann, W.; Dufour, J. F. Significance of serum adiponectin levels in patients with chronic liver disease. Clin. Sci., 2010, 119(10), 431-436.
    • (2010) Clin. Sci. , vol.119 , Issue.10 , pp. 431-436
    • Balmer, M.L.1    Joneli, J.2    Schoepfer, A.3    Stickel, F.4    Thormann, W.5    Dufour, J.F.6
  • 69
    • 79956269169 scopus 로고    scopus 로고
    • The association between serum adiponectin levels and nutritional status of hemodialysis patients
    • Lee, Y. J.; Cho, S.; Kim, S. R. The association between serum adiponectin levels and nutritional status of hemodialysis patients. Ren. Fail., 2011, 33(5), 506-511.
    • (2011) Ren. Fail. , vol.33 , Issue.5 , pp. 506-511
    • Lee, Y.J.1    Cho, S.2    Kim, S.R.3
  • 70
    • 78650707102 scopus 로고    scopus 로고
    • Adiponectin in chronic kidney disease: A complex and context sensitive clinical situation
    • Stenvinkel, P. Adiponectin in chronic kidney disease: a complex and context sensitive clinical situation. J. Ren. Nutr., 2011, 21(1), 82-86.
    • (2011) J. Ren. Nutr. , vol.21 , Issue.1 , pp. 82-86
    • Stenvinkel, P.1
  • 71
    • 0041302377 scopus 로고    scopus 로고
    • The fatderived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu, A.; Wang, Y.; Keshaw, H.; Xu, L. Y.; Lam, K. S.; Cooper, G. J. The fatderived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J. Clin. Invest, 2003, 112(1), 91-100.
    • (2003) J. Clin. Invest , vol.112 , Issue.1 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 73
    • 3042699353 scopus 로고    scopus 로고
    • Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice
    • Masaki, T.; Chiba, S.; Tatsukawa, H.; Yasuda, T.; Noguchi, H.; Seike, M.; Yoshimatsu, H. Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice. Hepatology, 2004, 40(1), 177-184.
    • (2004) Hepatology , vol.40 , Issue.1 , pp. 177-184
    • Masaki, T.1    Chiba, S.2    Tatsukawa, H.3    Yasuda, T.4    Noguchi, H.5    Seike, M.6    Yoshimatsu, H.7
  • 75
    • 39549093795 scopus 로고    scopus 로고
    • High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase
    • Adachi, M.; Brenner, D. A. High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase. Hepatology, 2008, 47(2), 677-685.
    • (2008) Hepatology , vol.47 , Issue.2 , pp. 677-685
    • Adachi, M.1    Brenner, D.A.2
  • 76
    • 79959439461 scopus 로고    scopus 로고
    • Adiponectin regulation of stellate cell activation via PPARgamma-dependent and - Independent mechanisms
    • Shafiei, M. S.; Shetty, S.; Scherer, P. E.; Rockey, D. C. Adiponectin regulation of stellate cell activation via PPARgamma-dependent and - independent mechanisms. Am. J. Pathol., 2011, 178(6), 2690-2699.
    • (2011) Am. J. Pathol. , vol.178 , Issue.6 , pp. 2690-2699
    • Shafiei, M.S.1    Shetty, S.2    Scherer, P.E.3    Rockey, D.C.4
  • 82
    • 78049478003 scopus 로고    scopus 로고
    • Adiponectin modulates C-jun Nterminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma
    • 1773 e1761-1765
    • Saxena, N. K.; Fu, P. P.; Nagalingam, A.; Wang, J.; Handy, J.; Cohen, C.; Tighiouart, M.; Sharma, D.; Anania, F. A. Adiponectin modulates C-jun Nterminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma. Gastroenterology, 2010, 139(5), 1762-1773, 1773 e1761-1765.
    • (2010) Gastroenterology , vol.139 , Issue.5 , pp. 1762-1773
    • Saxena, N.K.1    Fu, P.P.2    Nagalingam, A.3    Wang, J.4    Handy, J.5    Cohen, C.6    Tighiouart, M.7    Sharma, D.8    Anania, F.A.9
  • 86
    • 78650039966 scopus 로고    scopus 로고
    • Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice
    • Duval, C.; Thissen, U.; Keshtkar, S.; Accart, B.; Stienstra, R.; Boekschoten, M. V.; Roskams, T.; Kersten, S.; Muller, M. Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice. Diabetes, 2010, 59(12), 3181-3191.
    • (2010) Diabetes , vol.59 , Issue.12 , pp. 3181-3191
    • Duval, C.1    Thissen, U.2    Keshtkar, S.3    Accart, B.4    Stienstra, R.5    Boekschoten, M.V.6    Roskams, T.7    Kersten, S.8    Muller, M.9
  • 87
    • 34249900491 scopus 로고    scopus 로고
    • Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo
    • Ouedraogo, R.; Gong, Y.; Berzins, B.; Wu, X.; Mahadev, K.; Hough, K.; Chan, L.; Goldstein, B. J.; Scalia, R. Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo. J. Clin. Invest., 2007, 117(6), 1718-1726.
    • (2007) J. Clin. Invest. , vol.117 , Issue.6 , pp. 1718-1726
    • Ouedraogo, R.1    Gong, Y.2    Berzins, B.3    Wu, X.4    Mahadev, K.5    Hough, K.6    Chan, L.7    Goldstein, B.J.8    Scalia, R.9
  • 91
    • 54449085766 scopus 로고    scopus 로고
    • Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury
    • Zhou, M.; Xu, A.; Tam, P. K.; Lam, K. S.; Chan, L.; Hoo, R. L.; Liu, J.; Chow, K. H.; Wang, Y. Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury. Hepatology, 2008, 48(4), 1087-1096.
    • (2008) Hepatology , vol.48 , Issue.4 , pp. 1087-1096
    • Zhou, M.1    Xu, A.2    Tam, P.K.3    Lam, K.S.4    Chan, L.5    Hoo, R.L.6    Liu, J.7    Chow, K.H.8    Wang, Y.9


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