MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: Potential role of ERK in VLDL-apoB100 particle assembly

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 27, Issue 1, 2007, Pages 211-218

  Tsai, Julie ^b   Qiu, Wei ^b   Kohen Avramoglu, Rita ^b   Adeli, Khosrow ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NONE

Author keywords

Apolipoprotein B100; HepG2; MEK ERK; VLDL

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 ETHYL 2 (4 METHOXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; APOLIPOPROTEIN B100; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; OLEIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; U 0124; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; 1,3 BUTADIENE DERIVATIVE; DGAT1 PROTEIN, HUMAN; DGAT2 PROTEIN, HUMAN; DIACYLGLYCEROL ACYLTRANSFERASE; ENZYME INHIBITOR; MAP2K1 PROTEIN, HUMAN; MAP2K2 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; NITRILE; TRIACYLGLYCEROL;

ANIMAL CELL; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; STATISTICAL SIGNIFICANCE; ANIMAL; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; HEPATOBLASTOMA; LIVER TUMOR; METABOLISM; PARTICLE SIZE; PATHOLOGY; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SYRIAN HAMSTER; TUMOR CELL LINE;

ANIMALS; APOLIPOPROTEIN B-100; BUTADIENES; CELL LINE, TUMOR; CRICETINAE; DIACYLGLYCEROL O-ACYLTRANSFERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HEPATOBLASTOMA; HEPATOCYTES; HUMANS; LIPOPROTEINS, VLDL; LIVER NEOPLASMS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MESOCRICETUS; NITRILES; OLEIC ACID; PARTICLE SIZE; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

EID: 33847618703     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000249861.80471.96     Document Type: Article

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