메뉴 건너뛰기




Volumn , Issue , 2012, Pages

PPARs in liver diseases and cancer: Epigenetic regulation by microRNAs

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; CHOLESTEROL; GLUCOSE; LIPID; MICRORNA; MICRORNA 145; MICRORNA 155; MICRORNA 200; MICRORNA 216; MICRORNA 217; MICRORNA 218; MICRORNA 224; MICRORNA 32; MICRORNA 33; MICRORNA 34; MICRORNA 342; MICRORNA 374; MICRORNA 431; MICRORNA 491; MICRORNA 590; MICRORNA 615; MICRORNA 708; MICRORNA 873; MICRORNA 92; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84867370115     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2012/757803     Document Type: Review
Times cited : (54)

References (174)
  • 1
    • 33748301260 scopus 로고    scopus 로고
    • Global challenges in liver disease
    • DOI 10.1002/hep.21347
    • Williams R., Global challenges in liver disease. Hepatology 2006 44 3 521 526 2-s2.0-33748301260 10.1002/hep.21347 (Pubitemid 44433707)
    • (2006) Hepatology , vol.44 , Issue.3 , pp. 521-526
    • Williams, R.1
  • 2
    • 33846616400 scopus 로고    scopus 로고
    • Alcoholic liver disease
    • DOI 10.1053/j.semdp.2006.11.002, PII S0740257006001717, Inflammatory Liver Disease
    • Yip W. W., Burt A. D., Alcoholic liver disease. Seminars in Diagnostic Pathology 2006 23 3-4 149 160 2-s2.0-33846616400 10.1053/j.semdp.2006.11.002 (Pubitemid 46176510)
    • (2006) Seminars in Diagnostic Pathology , vol.23 , Issue.3-4 , pp. 149-160
    • Yip, W.W.1    Burt, A.D.2
  • 3
    • 33745637207 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and the metabolic syndrome
    • Marchesini G., Babini M., Nonalcoholic fatty liver disease and the metabolic syndrome. Minerva Cardioangiologica 2006 54 2 229 239 2-s2.0-33745637207 (Pubitemid 43974287)
    • (2006) Minerva Cardioangiologica , vol.54 , Issue.2 , pp. 229-239
    • Marchesini, G.1    Babini, M.2
  • 4
    • 84860287080 scopus 로고    scopus 로고
    • Epidemiology of viral hepatitis and hepatocellular carcinoma
    • 2-s2.0-84860287080 10.1053/j.gastro.2011.12.061
    • El-Serag H. B., Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 2012 142 6 1264.e1 1273.e1 2-s2.0-84860287080 10.1053/j.gastro.2011.12.061
    • (2012) Gastroenterology , vol.142 , Issue.6
    • El-Serag, H.B.1
  • 5
    • 84860308049 scopus 로고    scopus 로고
    • Prevention of hepatocellular carcinoma: Progress and challenges
    • 2-s2.0-84860308049
    • Shire A. M., Roberts L. R., Prevention of hepatocellular carcinoma: progress and challenges. Minerva Gastroenterologica e Dietologica 2012 58 1 49 64 2-s2.0-84860308049
    • (2012) Minerva Gastroenterologica e Dietologica , vol.58 , Issue.1 , pp. 49-64
    • Shire, A.M.1    Roberts, L.R.2
  • 6
    • 79959296814 scopus 로고    scopus 로고
    • The global epidemiology of hepatocellular carcinoma: Present and future
    • 2-s2.0-79959296814 10.1016/j.cld.2011.03.006
    • McGlynn K. A., London W. T., The global epidemiology of hepatocellular carcinoma: present and future. Clinics in Liver Disease 2011 15 2 223 243 2-s2.0-79959296814 10.1016/j.cld.2011.03.006
    • (2011) Clinics in Liver Disease , vol.15 , Issue.2 , pp. 223-243
    • McGlynn, K.A.1    London, W.T.2
  • 7
    • 79961218135 scopus 로고    scopus 로고
    • Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: A systematic review and meta-analysis of cohort studies
    • 2-s2.0-79960653870 10.1002/ijc.26165
    • Wang C., Wang X., Gong G., Ben Q., Qiu W., Chen Y., Li G., Wang L., Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: a systematic review and meta-analysis of cohort studies. International Journal of Cancer 2012 130 7 1639 1648 2-s2.0-79960653870 10.1002/ijc.26165
    • (2012) International Journal of Cancer , vol.130 , Issue.7 , pp. 1639-1648
    • Wang, C.1    Wang, X.2    Gong, G.3    Ben, Q.4    Qiu, W.5    Chen, Y.6    Li, G.7    Wang, L.8
  • 8
    • 79955485194 scopus 로고    scopus 로고
    • Molecular pathogenesis of hepatocellular carcinoma
    • 2-s2.0-79955485194 10.1111/j.1530-0277.2010.01406.x
    • Cornellà H., Alsinet C., Villanueva A., Molecular pathogenesis of hepatocellular carcinoma. Alcoholism 2011 35 5 821 825 2-s2.0-79955485194 10.1111/j.1530-0277.2010.01406.x
    • (2011) Alcoholism , vol.35 , Issue.5 , pp. 821-825
    • Cornellà, H.1    Alsinet, C.2    Villanueva, A.3
  • 9
    • 4344581329 scopus 로고    scopus 로고
    • The histologic spectrum of nonalcoholic fatty liver disease
    • DOI 10.1016/j.cld.2004.04.013, PII S1089326104000431
    • Contos M. J., Choudhury J., Mills A. S., Sanyal A. J., The histologic spectrum of nonalcoholic fatty liver disease. Clinics in Liver Disease 2004 8 3 481 500 2-s2.0-4344581329 10.1016/j.cld.2004.04.013 (Pubitemid 39141138)
    • (2004) Clinics in Liver Disease , vol.8 , Issue.3 , pp. 481-500
    • Contos, M.J.1    Choudhury, J.2    Mills, A.S.3    Sanyal, A.J.4
  • 10
    • 24044536090 scopus 로고    scopus 로고
    • Recent concepts in non-alcoholic fatty liver disease
    • DOI 10.1111/j.1464-5491.2005.01748.x
    • Adams L. A., Angulo P., Recent concepts in non-alcoholic fatty liver disease. Diabetic Medicine 2005 22 9 1129 1133 2-s2.0-24044536090 10.1111/j.1464-5491.2005.01748.x (Pubitemid 41224168)
    • (2005) Diabetic Medicine , vol.22 , Issue.9 , pp. 1129-1133
    • Adams, L.A.1    Angulo, P.2
  • 11
    • 7044235603 scopus 로고    scopus 로고
    • Obesity and hepatocellular carcinoma
    • DOI 10.1053/j.gastro.2004.09.021, PII S0016508504016002
    • Caldwell S. H., Crespo D. M., Kang H. S., Al-Osaimi A. M. S., Obesity and hepatocellular carcinoma. Gastroenterology 2004 127 5 supplement 1 S97 S103 2-s2.0-7044235603 10.1053/j.gastro.2004.09.021 (Pubitemid 39423375)
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL.
    • Caldwell, S.H.1    Crespo, D.M.2    Kang, H.S.3    Al-Osaimi, A.M.S.4
  • 12
    • 33644759114 scopus 로고    scopus 로고
    • The association between diabetes and hepatocellular carcinoma: A systematic review of epidemiologic evidence
    • DOI 10.1016/j.cgh.2005.12.007, PII S154235650501178X
    • El-Serag H. B., Hampel H., Javadi F., The association between diabetes and hepatocellular carcinoma: a systematic review of epidemiologic evidence. Clinical Gastroenterology and Hepatology 2006 4 3 369 380 2-s2.0-33644759114 10.1016/j.cgh.2005.12.007 (Pubitemid 43343895)
    • (2006) Clinical Gastroenterology and Hepatology , vol.4 , Issue.3 , pp. 369-380
    • El-Serag, H.B.1    Hampel, H.2    Javadi, F.3
  • 13
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • DOI 10.1038/nrc1934, PII NRC1934
    • Farazi P. A., DePinho R. A., Hepatocellular carcinoma pathogenesis: from genes to environment. Nature Reviews Cancer 2006 6 9 674 687 2-s2.0-33747830764 10.1038/nrc1934 (Pubitemid 44286000)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.9 , pp. 674-687
    • Farazi, P.A.1    DePinho, R.A.2
  • 15
    • 77950233673 scopus 로고    scopus 로고
    • A fresh look at NASH pathogenesis. Part 1: The metabolic movers
    • 2-s2.0-77950233673 10.1111/j.1440-1746.2010.06253.x
    • Larter C. Z., Chitturi S., Heydet D., Farrell G. C., A fresh look at NASH pathogenesis. Part 1: the metabolic movers. Journal of Gastroenterology and Hepatology 2010 25 4 672 690 2-s2.0-77950233673 10.1111/j.1440-1746.2010.06253.x
    • (2010) Journal of Gastroenterology and Hepatology , vol.25 , Issue.4 , pp. 672-690
    • Larter, C.Z.1    Chitturi, S.2    Heydet, D.3    Farrell, G.C.4
  • 16
    • 67649448956 scopus 로고    scopus 로고
    • Molecular mechanisms involved in NAFLD progression
    • 2-s2.0-67649448956 10.1007/s00109-009-0464-1
    • Malaguarnera M., Di Rosa M., Nicoletti F., Malaguarnera L., Molecular mechanisms involved in NAFLD progression. Journal of Molecular Medicine 2009 87 7 679 695 2-s2.0-67649448956 10.1007/s00109-009-0464-1
    • (2009) Journal of Molecular Medicine , vol.87 , Issue.7 , pp. 679-695
    • Malaguarnera, M.1    Di Rosa, M.2    Nicoletti, F.3    Malaguarnera, L.4
  • 17
    • 77949311823 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A review and update
    • 2-s2.0-77949311823 10.1007/s10620-009-1081-0
    • Lewis J. R., Mohanty S. R., Nonalcoholic fatty liver disease: a review and update. Digestive Diseases and Sciences 2010 55 3 560 578 2-s2.0-77949311823 10.1007/s10620-009-1081-0
    • (2010) Digestive Diseases and Sciences , vol.55 , Issue.3 , pp. 560-578
    • Lewis, J.R.1    Mohanty, S.R.2
  • 18
    • 77952573691 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis
    • 2-s2.0-77952573691 10.1159/000282094
    • Rombouts K., Marra F., Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis. Digestive Diseases 2010 28 1 229 235 2-s2.0-77952573691 10.1159/000282094
    • (2010) Digestive Diseases , vol.28 , Issue.1 , pp. 229-235
    • Rombouts, K.1    Marra, F.2
  • 19
    • 58149466606 scopus 로고    scopus 로고
    • PPARs mediate lipid signaling in inflammation and cancer
    • 2-s2.0-58149466606 10.1155/2008/134059 134059
    • Michalik L., Wahli W., PPARs mediate lipid signaling in inflammation and cancer. PPAR Research 2008 23 7 351 363 2-s2.0-58149466606 10.1155/2008/134059 134059
    • (2008) PPAR Research , vol.23 , Issue.7 , pp. 351-363
    • Michalik, L.1    Wahli, W.2
  • 20
    • 79959287496 scopus 로고    scopus 로고
    • Role of class II nuclear receptors in liver carcinogenesis
    • 2-s2.0-79959287496
    • Li G., Guo G. L., Role of class II nuclear receptors in liver carcinogenesis. Anti-Cancer Agents in Medicinal Chemistry 2011 11 6 529 542 2-s2.0-79959287496
    • (2011) Anti-Cancer Agents in Medicinal Chemistry , vol.11 , Issue.6 , pp. 529-542
    • Li, G.1    Guo, G.L.2
  • 22
    • 84859157277 scopus 로고    scopus 로고
    • Roles of PPARs in NAFLD: Potential therapeutic targets
    • 2-s2.0-84859157277 10.1016/j.bbalip.2011.10.016
    • Tailleux A., Wouters K., Staels B., Roles of PPARs in NAFLD: potential therapeutic targets. Biochimica et Biophysica Acta 2012 1821 5 809 818 2-s2.0-84859157277 10.1016/j.bbalip.2011.10.016
    • (2012) Biochimica et Biophysica Acta , vol.1821 , Issue.5 , pp. 809-818
    • Tailleux, A.1    Wouters, K.2    Staels, B.3
  • 23
    • 39849099238 scopus 로고    scopus 로고
    • Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease
    • DOI 10.3748/wjg.14.22
    • Kallwitz E. R., McLachlan A., Cotler S. J., Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease. World Journal of Gastroenterology 2008 14 1 22 28 2-s2.0-39849099238 10.3748/wjg.14.22 (Pubitemid 351314322)
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.1 , pp. 22-28
    • Kallwitz, E.R.1    McLachlan, A.2    Cotler, S.J.3
  • 24
    • 79955650290 scopus 로고    scopus 로고
    • Up-regulation of PPAR- γ mRNA expression in the liver of obese patients: An additional reinforcing lipogenic mechanism to SREBP-1c induction
    • 2-s2.0-79955650290 10.1210/jc.2010-2129
    • Pettinelli P., Videla L. A., Up-regulation of PPAR- γ mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c induction. Journal of Clinical Endocrinology and Metabolism 2011 96 5 1424 1430 2-s2.0-79955650290 10.1210/jc.2010-2129
    • (2011) Journal of Clinical Endocrinology and Metabolism , vol.96 , Issue.5 , pp. 1424-1430
    • Pettinelli, P.1    Videla, L.A.2
  • 27
    • 79955868038 scopus 로고    scopus 로고
    • An increase in liver PPAR γ 2 is an initial event to induce fatty liver in response to a diet high in butter: PPAR γ 2 knockdown improves fatty liver induced by high-saturated fat
    • 2-s2.0-79955868038 10.1016/j.jnutbio.2010.04.009
    • Yamazaki T., Shiraishi S., Kishimoto K., Miura S., Ezaki O., An increase in liver PPAR γ 2 is an initial event to induce fatty liver in response to a diet high in butter: PPAR γ 2 knockdown improves fatty liver induced by high-saturated fat. Journal of Nutritional Biochemistry 2011 22 6 543 553 2-s2.0-79955868038 10.1016/j.jnutbio.2010.04.009
    • (2011) Journal of Nutritional Biochemistry , vol.22 , Issue.6 , pp. 543-553
    • Yamazaki, T.1    Shiraishi, S.2    Kishimoto, K.3    Miura, S.4    Ezaki, O.5
  • 28
    • 77949916811 scopus 로고    scopus 로고
    • Enhanced steatosis by nuclear receptor ligands: A study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile
    • 2-s2.0-77949916811 10.1016/j.cbi.2010.01.008
    • Moya M., José Gómez-Lechón M., Castell J. V., Jover R., Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. Chemico-Biological Interactions 2010 184 3 376 387 2-s2.0-77949916811 10.1016/j.cbi.2010.01.008
    • (2010) Chemico-Biological Interactions , vol.184 , Issue.3 , pp. 376-387
    • Moya, M.1    José Gómez-Lechón, M.2    Castell, J.V.3    Jover, R.4
  • 29
    • 78649741621 scopus 로고    scopus 로고
    • The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats
    • 2-s2.0-78649741621 10.1016/j.ejphar.2010.09.082
    • Liu S., Wu H. J., Zhang Z. Q., Chen Q., Liu B., Wu J. P., Zhu L., The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats. European Journal of Pharmacology 2011 650 1 384 389 2-s2.0-78649741621 10.1016/j.ejphar.2010.09.082
    • (2011) European Journal of Pharmacology , vol.650 , Issue.1 , pp. 384-389
    • Liu, S.1    Wu, H.J.2    Zhang, Z.Q.3    Chen, Q.4    Liu, B.5    Wu, J.P.6    Zhu, L.7
  • 30
    • 79955939296 scopus 로고    scopus 로고
    • A novel agonist of PPAR- γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance
    • 2-s2.0-79955939296 10.1016/j.ejphar.2011.03.033
    • Zheng H., Li S., Ma L., Cheng L., Deng C., Chen Z., Xie C., Xiang M., Jiang W., Chen L., A novel agonist of PPAR- γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance. European Journal of Pharmacology 2011 659 2-3 244 251 2-s2.0-79955939296 10.1016/j.ejphar.2011.03. 033
    • (2011) European Journal of Pharmacology , vol.659 , Issue.2-3 , pp. 244-251
    • Zheng, H.1    Li, S.2    Ma, L.3    Cheng, L.4    Deng, C.5    Chen, Z.6    Xie, C.7    Xiang, M.8    Jiang, W.9    Chen, L.10
  • 32
    • 37249059359 scopus 로고    scopus 로고
    • PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes
    • DOI 10.1111/j.1440-1746.2006.04819.x
    • Seo Y. S., Kim J. H., Jo N. Y., Choi K. M., Baik S. H., Park J. J., Kim J. S., Byun K. S., Bak Y. T., Lee C. H., Kim A., Yeon J. E., PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes. Journal of Gastroenterology and Hepatology 2008 23 1 102 109 2-s2.0-37249059359 10.1111/j.1440-1746.2006.04819.x (Pubitemid 350265194)
    • (2008) Journal of Gastroenterology and Hepatology , vol.23 , Issue.1 , pp. 102-109
    • Seo, Y.S.1    Kim, J.H.2    Jo, N.Y.3    Choi, K.M.4    Baik, S.H.5    Park, J.-J.6    Kim, J.S.7    Byun, K.S.8    Bak, Y.-T.9    Lee, C.H.10    Kim, A.11    Yeon, J.E.12
  • 33
    • 33746340885 scopus 로고    scopus 로고
    • Changes in Serum Adipokine Levels During Pioglitazone Treatment for Nonalcoholic Steatohepatitis: Relationship to Histological Improvement
    • DOI 10.1016/j.cgh.2006.05.005, PII S1542356506004708
    • Lutchman G., Promrat K., Kleiner D. E., Heller T., Ghany M. G., Yanovski J. A., Liang T. J., Hoofnagle J. H., Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement. Clinical Gastroenterology and Hepatology 2006 4 8 1048 1052 2-s2.0-33746340885 10.1016/j.cgh.2006.05.005 (Pubitemid 44118842)
    • (2006) Clinical Gastroenterology and Hepatology , vol.4 , Issue.8 , pp. 1048-1052
    • Lutchman, G.1    Promrat, K.2    Kleiner, D.E.3    Heller, T.4    Ghany, M.G.5    Yanovski, J.A.6    Liang, T.J.7    Hoofnagle, J.H.8
  • 34
    • 46349088361 scopus 로고    scopus 로고
    • Rosiglitazone for Nonalcoholic Steatohepatitis: One-Year Results of the Randomized Placebo-Controlled Fatty Liver Improvement With Rosiglitazone Therapy (FLIRT) Trial
    • DOI 10.1053/j.gastro.2008.03.078, PII S0016508508006306
    • Ratziu V., Giral P., Jacqueminet S., Charlotte F., Hartemann-Heurtier A., Serfaty L., Podevin P., Lacorte J. M., Bernhardt C., Bruckert E., Grimaldi A., Poynard T., Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial. Gastroenterology 2008 135 1 100 110 2-s2.0-46349088361 10.1053/j.gastro.2008.03.078 (Pubitemid 351916703)
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 100-110
    • Ratziu, V.1    Giral, P.2    Jacqueminet, S.3    Charlotte, F.4    Hartemann-Heurtier, A.5    Serfaty, L.6    Podevin, P.7    Lacorte, J.8    Bernhardt, C.9    Bruckert, E.10    Grimaldi, A.11    Poynard, T.12
  • 37
    • 39549113664 scopus 로고    scopus 로고
    • Effect of peroxisome proliferator-activated receptors-γ and co-activator-1α genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people
    • DOI 10.1111/j.1478-3231.2007.01623.x
    • Hui Y., Yu-yuan L., Yu-qiang N., Wei-hong S., Yan-lei D., Xiao-bo L., Yong-jian Z., Effect of peroxisome proliferator-activated receptors- γ and co-activator-1 α genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people. Liver International 2008 28 3 385 392 2-s2.0-39549113664 10.1111/j.1478-3231.2007. 01623.x (Pubitemid 351279587)
    • (2008) Liver International , vol.28 , Issue.3 , pp. 385-392
    • Hui, Y.1    Yu-yuan, L.2    Yu-qiang, N.3    Wei-hong, S.4    Yan-lei, D.5    Xiao-bo, L.6    Yong-jian, Z.7
  • 38
    • 78650592847 scopus 로고    scopus 로고
    • Pro12Ala polymorphism of the peroxisome proliferatoractivated receptor γ 2 in patients with fatty liver diseases
    • 2-s2.0-78650592847 10.3748/wjg.v16.i46.5830
    • Rey J. W., Noetel A., Hardt A., Canbay A., Alakus H., zur Hausen A., Dienes H. P., Drebber U., Odenthal M., Pro12Ala polymorphism of the peroxisome proliferatoractivated receptor γ 2 in patients with fatty liver diseases. World Journal of Gastroenterology 2010 16 46 5830 5837 2-s2.0-78650592847 10.3748/wjg.v16.i46.5830
    • (2010) World Journal of Gastroenterology , vol.16 , Issue.46 , pp. 5830-5837
    • Rey, J.W.1    Noetel, A.2    Hardt, A.3    Canbay, A.4    Alakus, H.5    Zur Hausen, A.6    Dienes, H.P.7    Drebber, U.8    Odenthal, M.9
  • 39
    • 84864073994 scopus 로고    scopus 로고
    • Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD
    • Gawrieh S., Gawrieh S., Marion M. C., Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD. Digestive Diseases and Sciences 2012 57 4 952 957
    • (2012) Digestive Diseases and Sciences , vol.57 , Issue.4 , pp. 952-957
    • Gawrieh, S.1    Gawrieh, S.2    Marion, M.C.3
  • 40
    • 80755189999 scopus 로고    scopus 로고
    • PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatty liver in middle-aged and older Chinese population
    • 2-s2.0-80755189999 10.1016/j.mce.2011.09.001
    • Yang Z., Wen J., Li Q., Tao X., Ye Z., He M., Zhang W., Huang Y., Chen L., Ling C., Qu S., Hu R., PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatty liver in middle-aged and older Chinese population. Molecular and Cellular Endocrinology 2012 348 1 255 259 2-s2.0-80755189999 10.1016/j.mce.2011.09.001
    • (2012) Molecular and Cellular Endocrinology , vol.348 , Issue.1 , pp. 255-259
    • Yang, Z.1    Wen, J.2    Li, Q.3    Tao, X.4    Ye, Z.5    He, M.6    Zhang, W.7    Huang, Y.8    Chen, L.9    Ling, C.10    Qu, S.11    Hu, R.12
  • 41
    • 79952631265 scopus 로고    scopus 로고
    • Peroxisome proliferators-activated receptor γ 2 Pro12Ala variant is associated with body mass index in non-alcoholic fatty liver disease patients
    • 2-s2.0-79952631265 10.1007/s12072-010-9225-z
    • Gupta A. C., Chaudhory A. K., Sukriti, Pande C., Sakhuja P., Singh Y., Basir S. F., Sarin S. K., Peroxisome proliferators-activated receptor γ 2 Pro12Ala variant is associated with body mass index in non-alcoholic fatty liver disease patients. Hepatology International 2011 5 1 575 580 2-s2.0-79952631265 10.1007/s12072-010-9225-z
    • (2011) Hepatology International , vol.5 , Issue.1 , pp. 575-580
    • Gupta, A.C.1    Chaudhory, A.K.2    Sukriti3    Pande, C.4    Sakhuja, P.5    Singh, Y.6    Basir, S.F.7    Sarin, S.K.8
  • 42
    • 3242795074 scopus 로고    scopus 로고
    • Reduced expression of peroxisome proliferator-activated receptor-α may have an important role in the development of non-alcoholic fatty liver disease
    • DOI 10.1111/j.1440-1746.2004.03349.x
    • Jong E. Y., Kyung M. C., Sei H. B., Kyoung O. K., Hyoung J. L., Ki H. P., Jin Y. K., Park J. J., Jae S. K., Bak Y. T., Kwan S. B., Chang H. L., Reduced expression of peroxisome proliferator-activated receptor- α may have an important role in the development of non-alcoholic fatty liver disease. Journal of Gastroenterology and Hepatology 2004 19 7 799 804 2-s2.0-3242795074 10.1111/j.1440-1746.2004.03349.x (Pubitemid 38981403)
    • (2004) Journal of Gastroenterology and Hepatology , vol.19 , Issue.7 , pp. 799-804
    • Jong, E.Y.1    Kyung, M.C.2    Sei, H.B.3    Kyoung, O.K.4    Hyoung, J.L.5    Ki, H.P.6    Jin, Y.K.7    Park, J.-J.8    Jae, S.K.9    Bak, Y.-T.10    Kwan, S.B.11    Chang, H.L.12
  • 44
    • 79955504163 scopus 로고    scopus 로고
    • PPAR α expression protects male mice from high fat-induced nonalcoholic fatty liver
    • 2-s2.0-79955504163 10.3945/jn.110.135210
    • Abdelmegeed M. A., Yoo S. H., Henderson L. E., Gonzalez F. J., Woodcroft K. J., Song B. J., PPAR α expression protects male mice from high fat-induced nonalcoholic fatty liver. Journal of Nutrition 2011 141 4 603 610 2-s2.0-79955504163 10.3945/jn.110.135210
    • (2011) Journal of Nutrition , vol.141 , Issue.4 , pp. 603-610
    • Abdelmegeed, M.A.1    Yoo, S.H.2    Henderson, L.E.3    Gonzalez, F.J.4    Woodcroft, K.J.5    Song, B.J.6
  • 45
    • 33646812161 scopus 로고    scopus 로고
    • Fenofibrate, a peroxisome proliferator-activated receptor α agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver
    • 2-s2.0-33646812161 10.1111/j.1478-3231.2006.01265.x
    • Harano Y., Yasui K., Toyama T., Nakajima T., Mitsuyoshi H., Mimani M., Hirasawa T., Itoh Y., Okanoue T., Fenofibrate, a peroxisome proliferator- activated receptor α agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver. Liver International 2006 26 5 613 620 2-s2.0-33646812161 10.1111/j.1478-3231.2006. 01265.x
    • (2006) Liver International , vol.26 , Issue.5 , pp. 613-620
    • Harano, Y.1    Yasui, K.2    Toyama, T.3    Nakajima, T.4    Mitsuyoshi, H.5    Mimani, M.6    Hirasawa, T.7    Itoh, Y.8    Okanoue, T.9
  • 46
    • 84856139907 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor- α agonist, Wy 14643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis
    • 2-s2.0-84856139907 10.1111/j.1440-1746.2011.06939.x
    • Larter C. Z., Yeh M. M., van Rooyen D. M., Brooling J., Ghatora K., Farrell G. C., Peroxisome proliferator-activated receptor- α agonist, Wy 14643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis. Journal of Gastroenterology and Hepatology 2012 27 2 341 350 2-s2.0-84856139907 10.1111/j.1440-1746.2011.06939.x
    • (2012) Journal of Gastroenterology and Hepatology , vol.27 , Issue.2 , pp. 341-350
    • Larter, C.Z.1    Yeh, M.M.2    Van Rooyen, D.M.3    Brooling, J.4    Ghatora, K.5    Farrell, G.C.6
  • 47
    • 84855180612 scopus 로고    scopus 로고
    • Inhibition of aldose reductase activates hepatic peroxisome proliferator-activated receptor- α and ameliorates hepatosteatosis in diabetic db/db mice
    • 789730 2-s2.0-84855180612 10.1155/2012/789730
    • Qiu L., Lin J., Xu F., Gao Y., Zhang C., Liu Y., Luo Y., Yang J. Y., Inhibition of aldose reductase activates hepatic peroxisome proliferator- activated receptor- α and ameliorates hepatosteatosis in diabetic db/db mice. Experimental Diabetes Research 2012 2012 789730 2-s2.0-84855180612 10.1155/2012/789730
    • (2012) Experimental Diabetes Research , vol.2012
    • Qiu, L.1    Lin, J.2    Xu, F.3    Gao, Y.4    Zhang, C.5    Liu, Y.6    Luo, Y.7    Yang, J.Y.8
  • 48
    • 39149132072 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor α by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation
    • DOI 10.1111/j.1440-1746.2007.05157.x
    • Larter C. Z., Yeh M. M., Cheng J., Williams J., Brown S., Dela Pena A., Bell-Anderson K. S., Farrell G. C., Activation of peroxisome proliferator-activated receptor α by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation. Journal of Gastroenterology and Hepatology 2008 23 2 267 275 2-s2.0-39149132072 10.1111/j.1440-1746.2007.05157.x (Pubitemid 351257676)
    • (2008) Journal of Gastroenterology and Hepatology , vol.23 , Issue.2 , pp. 267-275
    • Larter, C.Z.1    Yeh, M.M.2    Cheng, J.3    Williams, J.4    Brown, S.5    Dela Pena, A.6    Bell-Anderson, K.S.7    Farrell, G.C.8
  • 49
    • 49849093922 scopus 로고    scopus 로고
    • A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio
    • 2-s2.0-49849093922 10.1111/j.1440-1746.2008.05523.x
    • Chen S., Li Y., Li S., Yu C., A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio. Journal of Gastroenterology and Hepatology 2008 23 9 1415 1418 2-s2.0-49849093922 10.1111/j.1440-1746.2008.05523.x
    • (2008) Journal of Gastroenterology and Hepatology , vol.23 , Issue.9 , pp. 1415-1418
    • Chen, S.1    Li, Y.2    Li, S.3    Yu, C.4
  • 51
    • 38749085998 scopus 로고    scopus 로고
    • A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease
    • DOI 10.1016/j.dld.2007.10.002, PII S1590865807005506
    • Fernández-Miranda C., Pérez-Carreras M., Colina F., López-Alonso G., Vargas C., Solís-Herruzo J. A., A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease. Digestive and Liver Disease 2008 40 3 200 205 2-s2.0-38749085998 10.1016/j.dld.2007.10.002 (Pubitemid 351181792)
    • (2008) Digestive and Liver Disease , vol.40 , Issue.3 , pp. 200-205
    • Fernandez-Miranda, C.1    Perez-Carreras, M.2    Colina, F.3    Lopez-Alonso, G.4    Vargas, C.5    Solis-Herruzo, J.A.6
  • 54
    • 77949676576 scopus 로고    scopus 로고
    • Transcriptional profiling reveals divergent roles of PPAR α and PPAR β / δ in regulation of gene expression in mouse liver
    • 2-s2.0-77949676576 10.1152/physiolgenomics.00127.2009
    • Sanderson L. M., Boekschoten M. V., Desvergne B., Müller M., Kersten S., Transcriptional profiling reveals divergent roles of PPAR α and PPAR β / δ in regulation of gene expression in mouse liver. Physiological Genomics 2010 41 1 42 52 2-s2.0-77949676576 10.1152/physiolgenomics.00127.2009
    • (2010) Physiological Genomics , vol.41 , Issue.1 , pp. 42-52
    • Sanderson, L.M.1    Boekschoten, M.V.2    Desvergne, B.3    Müller, M.4    Kersten, S.5
  • 55
    • 49649129066 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor- δ induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice
    • 2-s2.0-58149390235 10.1002/hep.22602
    • Sharma R., Torka P., Peroxisome proliferator-activated receptor- δ induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice. Hepatology 2008 48 6 432 441 2-s2.0-58149390235 10.1002/hep.22602
    • (2008) Hepatology , vol.48 , Issue.6 , pp. 432-441
    • Sharma, R.1    Torka, P.2
  • 57
    • 84856705923 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor (PPAR) beta/delta agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells
    • 2-s2.0-84856705923 10.1007/s00125-011-2401-4
    • Serrano-Marco L., Barroso E., El Kochairi I., Palomer X., Michalik L., Wahli W., Vázquez-Carrera M., The peroxisome proliferator-activated receptor (PPAR) beta/delta agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells. Diabetologia 2012 55 3 743 751 2-s2.0-84856705923 10.1007/s00125-011-2401-4
    • (2012) Diabetologia , vol.55 , Issue.3 , pp. 743-751
    • Serrano-Marco, L.1    Barroso, E.2    El Kochairi, I.3    Palomer, X.4    Michalik, L.5    Wahli, W.6    Vázquez-Carrera, M.7
  • 58
    • 79955368052 scopus 로고    scopus 로고
    • The PPAR β / δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1 α -lipin 1-PPAR α pathway leading to increased fatty acid oxidation
    • 2-s2.0-79955368052 10.1210/en.2010-1468
    • Barroso E., Rodríguez-Calvo R., Serrano-Marco L., Astudillo A. M., Balsinde J., Palomer X., Vázquez-Carrera M., The PPAR β / δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1 α -lipin 1-PPAR α pathway leading to increased fatty acid oxidation. Endocrinology 2011 152 5 1848 1859 2-s2.0-79955368052 10.1210/en.2010-1468
    • (2011) Endocrinology , vol.152 , Issue.5 , pp. 1848-1859
    • Barroso, E.1    Rodríguez-Calvo, R.2    Serrano-Marco, L.3    Astudillo, A.M.4    Balsinde, J.5    Palomer, X.6    Vázquez-Carrera, M.7
  • 59
    • 33645891166 scopus 로고    scopus 로고
    • Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPAR δ agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet
    • 2-s2.0-33645891166 10.1016/j.ejphar.2006.02.028
    • Nagasawa T., Inada Y., Nakano S., Tamura T., Takahashi T., Maruyama K., Yamazaki Y., Kuroda J., Shibata N., Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPAR δ agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet. European Journal of Pharmacology 2006 536 1-2 182 191 2-s2.0-33645891166 10.1016/j.ejphar.2006.02.028
    • (2006) European Journal of Pharmacology , vol.536 , Issue.1-2 , pp. 182-191
    • Nagasawa, T.1    Inada, Y.2    Nakano, S.3    Tamura, T.4    Takahashi, T.5    Maruyama, K.6    Yamazaki, Y.7    Kuroda, J.8    Shibata, N.9
  • 60
    • 79955919599 scopus 로고    scopus 로고
    • PPAR δ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle
    • 2-s2.0-79955919599 10.1111/j.1476-5381.2011.01240.x
    • Ye J. M., Tid-Ang J., Turner N., Zeng X. Y., Li H. Y., Cooney G. J., Wulff E. M., Sauerberg P., Kraegen E. W., PPAR δ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle. British Journal of Pharmacology 2011 163 3 556 566 2-s2.0-79955919599 10.1111/j.1476-5381.2011.01240.x
    • (2011) British Journal of Pharmacology , vol.163 , Issue.3 , pp. 556-566
    • Ye, J.M.1    Tid-Ang, J.2    Turner, N.3    Zeng, X.Y.4    Li, H.Y.5    Cooney, G.J.6    Wulff, E.M.7    Sauerberg, P.8    Kraegen, E.W.9
  • 61
    • 80051795701 scopus 로고    scopus 로고
    • Pharmacological activation of peroxisome proliferator-activated receptor delta improves insulin resistance and hepatic steatosis in high fat diet-induced diabetic mice
    • 2-s2.0-79959640457 10.1055/s-0031-1280781
    • Wu H. T., Chen C. T., Cheng K. C., Li Y. X., Yeh C. H., Cheng J. T., Pharmacological activation of peroxisome proliferator-activated receptor delta improves insulin resistance and hepatic steatosis in high fat diet-induced diabetic mice. Hormone and Metabolic Research 2011 43 9 631 635 2-s2.0-79959640457 10.1055/s-0031-1280781
    • (2011) Hormone and Metabolic Research , vol.43 , Issue.9 , pp. 631-635
    • Wu, H.T.1    Chen, C.T.2    Cheng, K.C.3    Li, Y.X.4    Yeh, C.H.5    Cheng, J.T.6
  • 65
    • 80052539818 scopus 로고    scopus 로고
    • MBX-8025, a novel peroxisome proliferator receptor-delta agonist: Lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin
    • 2-s2.0-80052539818 10.1210/jc.2011-1061
    • Bays H. E., Schwartz S., Littlejohn III T., Kerzner B., Krauss R. M., Karpf D. B., Choi Y.-J., Wang X., Naim S., Roberts B. K., MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin. Journal of Clinical Endocrinology and Metabolism 2011 96 9 2889 2897 2-s2.0-80052539818 10.1210/jc.2011-1061
    • (2011) Journal of Clinical Endocrinology and Metabolism , vol.96 , Issue.9 , pp. 2889-2897
    • Bays, H.E.1    Schwartz, S.2    Littlejohn Iii, T.3    Kerzner, B.4    Krauss, R.M.5    Karpf, D.B.6    Choi, Y.-J.7    Wang, X.8    Naim, S.9    Roberts, B.K.10
  • 68
    • 84855589241 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma cross-regulation of signaling events implicated in liver fibrogenesis
    • Zhang F., Lu Y., Zheng S., Peroxisome proliferator-activated receptor-gamma cross-regulation of signaling events implicated in liver fibrogenesis. Cell Signal 2012 24 3 596 605
    • (2012) Cell Signal , vol.24 , Issue.3 , pp. 596-605
    • Zhang, F.1    Lu, Y.2    Zheng, S.3
  • 69
  • 72
    • 33947400987 scopus 로고    scopus 로고
    • Effects of vitamin e treatment on peroxisome proliferator-activated receptor-α expression and insulin resistance in patients with non-alcoholic steatohepatitis: Results of a pilot study
    • DOI 10.1111/j.1445-5994.2006.01295.x
    • Yakaryilmaz F., Guliter S., Savas B., Erdem O., Ersoy R., Erden E., Akyol G., Bozkaya H., Ozenirler S., Effects of vitamin e treatment on peroxisome proliferator-activated receptor- α expression and insulin resistance in patients with non-alcoholic steatohepatitis: results of a pilot study. Internal Medicine Journal 2007 37 4 229 235 2-s2.0-33947400987 10.1111/j.1445-5994.2006. 01295.x (Pubitemid 46457497)
    • (2007) Internal Medicine Journal , vol.37 , Issue.4 , pp. 229-235
    • Yakaryilmaz, F.1    Guliter, S.2    Savas, B.3    Erdem, O.4    Ersoy, R.5    Erden, E.6    Akyol, G.7    Bozkaya, H.8    Ozenirler, S.9
  • 73
    • 38649104434 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-β/δ protects against chemically induced liver toxicity in mice
    • DOI 10.1002/hep.21925
    • Shan W., Nicol C. J., Ito S., Bility M. T., Kennett M. J., Ward J. M., Gonzalez F. J., Peters J. M., Peroxisome proliferator-activated receptor- β / δ protects against chemically induced liver toxicity in mice. Hepatology 2008 47 1 225 235 2-s2.0-38649104434 10.1002/hep.21925 (Pubitemid 351171060)
    • (2008) Hepatology , vol.47 , Issue.1 , pp. 225-235
    • Shan, W.1    Nicol, C.J.2    Ito, S.3    Bility, M.T.4    Kennett, M.J.5    Ward, J.M.6    Gonzalez, F.J.7    Peters, J.M.8
  • 74
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity
    • DOI 10.1016/j.cmet.2008.04.002, PII S1550413108001125
    • Kang K., Reilly S. M., Karabacak V., Gangl M. R., Fitzgerald K., Hatano B., Lee C. H., Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metabolism 2008 7 6 485 495 2-s2.0-44349112305 10.1016/j.cmet.2008.04.002 (Pubitemid 351729204)
    • (2008) Cell Metabolism , vol.7 , Issue.6 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3    Gangl, M.R.4    Fitzgerald, K.5    Hatano, B.6    Lee, C.-H.7
  • 75
    • 0037221210 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-β signaling contributes to enhanced proliferation of hepatic stellate cells
    • DOI 10.1053/gast.2003.50015
    • Hellemans K., Michalik L., Dittie A., Knorr A., Rombouts K., De Jong J., Heirman C., Quartier E., Schuit F., Wahli W., Geerts A., Peroxisome proliferator-activated receptor- β signaling contributes to enhanced proliferation of hepatic stellate cells. Gastroenterology 2003 124 1 184 201 2-s2.0-0037221210 10.1053/gast.2003.50015 (Pubitemid 36055351)
    • (2003) Gastroenterology , vol.124 , Issue.1 , pp. 184-201
    • Hellemans, K.1    Michalik, L.2    Dittie, A.3    Knorr, A.4    Rombouts, K.5    De Jong, J.6    Heirman, C.7    Quartier, E.8    Schuit, F.9    Wahli, W.10    Geerts, A.11
  • 76
    • 69249229453 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma
    • 2-s2.0-69249229453 10.1016/j.febslet.2009.07.034
    • Kim K., Kim K. H., Ha E., Park J. Y., Sakamoto N., Cheong J., Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma. FEBS Letters 2009 583 17 2720 2726 2-s2.0-69249229453 10.1016/j.febslet.2009.07.034
    • (2009) FEBS Letters , vol.583 , Issue.17 , pp. 2720-2726
    • Kim, K.1    Kim, K.H.2    Ha, E.3    Park, J.Y.4    Sakamoto, N.5    Cheong, J.6
  • 77
    • 33847633412 scopus 로고    scopus 로고
    • HCV core protein induces hepatic lipid accumulation by activating SREBP1 and PPARγ
    • DOI 10.1016/j.bbrc.2007.02.044, PII S0006291X07002987
    • Kim K. H., Hong S. P., Kim K., Park M. J., Kim K. J., Cheong J., HCV core protein induces hepatic lipid accumulation by activating SREBP1 and PPAR γ Biochemical and Biophysical Research Communications 2007 355 4 883 888 2-s2.0-33847633412 10.1016/j.bbrc.2007.02.044 (Pubitemid 46366910)
    • (2007) Biochemical and Biophysical Research Communications , vol.355 , Issue.4 , pp. 883-888
    • Kim, K.H.1    Hong, S.P.2    Kim, K.3    Park, M.J.4    Kim, K.J.5    Cheong, J.6
  • 79
    • 77954168704 scopus 로고    scopus 로고
    • Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR- γ in Huh-7 cells
    • 2-s2.0-77954168704 10.1099/vir.0.020644-0
    • Pazienza V., Vinciguerra M., Andriulli A., Mangia A., Hepatitis C virus core protein genotype 3a increases SOCS-7 expression through PPAR- γ in Huh-7 cells. Journal of General Virology 2010 91 1678 1686 2-s2.0-77954168704 10.1099/vir.0.020644-0
    • (2010) Journal of General Virology , vol.91 , pp. 1678-1686
    • Pazienza, V.1    Vinciguerra, M.2    Andriulli, A.3    Mangia, A.4
  • 80
    • 84867347828 scopus 로고    scopus 로고
    • Expression of COX-2 and PPARg in the livers of patients with acute on chronic HBV-related liver failure and their relationship with clinic parameters
    • Niu Y. H., Yi R. T., Liu H. L., Chen T. Y., Zhang S. L., Zhao Y. R., Expression of COX-2 and PPARg in the livers of patients with acute on chronic HBV-related liver failure and their relationship with clinic parameters. Zhonghua Gan Zang Bing Za Zhi 2011 19 7 511 516
    • (2011) Zhonghua Gan Zang Bing Za Zhi , vol.19 , Issue.7 , pp. 511-516
    • Niu, Y.H.1    Yi, R.T.2    Liu, H.L.3    Chen, T.Y.4    Zhang, S.L.5    Zhao, Y.R.6
  • 81
    • 34247637220 scopus 로고    scopus 로고
    • Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ
    • DOI 10.1053/j.gastro.2007.03.039, PII S001650850700563X
    • Kim K. H., Shin H. J., Kim K., Choi H. M., Rhee S. H., Moon H. B., Kim H. H., Yang U. S., Yu D. Y., Cheong J., Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma. Gastroenterology 2007 132 5 1955 1967 2-s2.0-34247637220 10.1053/j.gastro.2007. 03.039 (Pubitemid 46677949)
    • (2007) Gastroenterology , vol.132 , Issue.5 , pp. 1955-1967
    • Kim, K.H.1    Shin, H.2    Kim, K.3    Choi, H.M.4    Rhee, S.H.5    Moon, H.6    Kim, H.H.7    Yang, U.S.8    Yu, D.9    Cheong, J.10
  • 82
    • 9144250174 scopus 로고    scopus 로고
    • Hepatitis B virus X protein modulates peroxisome proliferator-activated receptor γ through protein-protein interaction
    • DOI 10.1016/S0014-5793(03)01449-2
    • Choi Y. H., Kim H. I., Seong J. K., Yu D. Y., Cho H., Lee M. O., Lee J. M., Ahn Y. H., Kim S. J., Park J. H., Hepatitis B virus X protein modulates peroxisome proliferator-activated receptor γ through protein-protein interaction. FEBS Letters 2004 557 13 73 80 2-s2.0-9144250174 10.1016/S0014-5793(03)01449-2 (Pubitemid 38115872)
    • (2004) FEBS Letters , vol.557 , Issue.1-3 , pp. 73-80
    • Choi, Y.-H.1    Kim, H.-I.2    Seong, J.K.3    Yu, D.-Y.4    Cho, H.5    Lee, M.-O.6    Lee, J.M.7    Ahn, Y.-H.8    Kim, S.J.9    Park, J.H.10
  • 83
    • 80655125493 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor gamma coactivator 1alpha in AKT/PKB-mediated inhibition of hepatitis B virus biosynthesis
    • Ondracek C. R., McLachlan A., Role of peroxisome proliferator-activated receptor gamma coactivator 1alpha in AKT/PKB-mediated inhibition of hepatitis B virus biosynthesis. Journal of Virology 2011 85 22 11891 11900
    • (2011) Journal of Virology , vol.85 , Issue.22 , pp. 11891-11900
    • Ondracek, C.R.1    McLachlan, A.2
  • 84
    • 78650279970 scopus 로고    scopus 로고
    • Adiponectin, a downstream target gene of peroxisome proliferator- activated receptor γ, controls hepatitis B virus replication
    • 2-s2.0-78650279970 10.1016/j.virol.2010.10.024
    • Yoon S., Jung J., Kim T., Park S., Chwae Y. J., Shin H. J., Kim K., Adiponectin, a downstream target gene of peroxisome proliferator-activated receptor γ controls hepatitis B virus replication. Virology 2011 409 2 290 298 2-s2.0-78650279970 10.1016/j.virol.2010.10.024
    • (2011) Virology , vol.409 , Issue.2 , pp. 290-298
    • Yoon, S.1    Jung, J.2    Kim, T.3    Park, S.4    Chwae, Y.J.5    Shin, H.J.6    Kim, K.7
  • 85
    • 77952743760 scopus 로고    scopus 로고
    • Inhibitory effect on hepatitis B virus in vitro by a peroxisome proliferator-activated receptor- γ ligand, rosiglitazone
    • 2-s2.0-77952743760 10.1016/j.bbrc.2010.04.128
    • Wakui Y., Inoue J., Ueno Y., Fukushima K., Kondo Y., Kakazu E., Obara N., Kimura O., Shimosegawa T., Inhibitory effect on hepatitis B virus in vitro by a peroxisome proliferator-activated receptor- γ ligand, rosiglitazone. Biochemical and Biophysical Research Communications 2010 396 2 508 514 2-s2.0-77952743760 10.1016/j.bbrc.2010.04.128
    • (2010) Biochemical and Biophysical Research Communications , vol.396 , Issue.2 , pp. 508-514
    • Wakui, Y.1    Inoue, J.2    Ueno, Y.3    Fukushima, K.4    Kondo, Y.5    Kakazu, E.6    Obara, N.7    Kimura, O.8    Shimosegawa, T.9
  • 86
    • 12744267799 scopus 로고    scopus 로고
    • Molecular mechanisms of alcoholic fatty liver: Role of peroxisome proliferator-activated receptor alpha
    • 2-s2.0-12744267799 10.1016/j.alcohol.2004.07.005
    • Crabb D. W., Galli A., Fischer M., You M., Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha. Alcohol 2004 34 1 35 38 2-s2.0-12744267799 10.1016/j.alcohol.2004.07.005
    • (2004) Alcohol , vol.34 , Issue.1 , pp. 35-38
    • Crabb, D.W.1    Galli, A.2    Fischer, M.3    You, M.4
  • 87
    • 74549189355 scopus 로고    scopus 로고
    • 'Hypothesis of seven balances': Molecular mechanisms behind alcoholic liver diseases and association with PPAR α
    • 2-s2.0-74549189355 10.1539/joh.K9001
    • Moriya T., Naito H., Ito Y., Nakajima T., 'Hypothesis of seven balances': molecular mechanisms behind alcoholic liver diseases and association with PPAR α Journal of Occupational Health 2009 51 5 391 403 2-s2.0-74549189355 10.1539/joh.K9001
    • (2009) Journal of Occupational Health , vol.51 , Issue.5 , pp. 391-403
    • Moriya, T.1    Naito, H.2    Ito, Y.3    Nakajima, T.4
  • 88
    • 82455162662 scopus 로고    scopus 로고
    • Alteration of hepatic nuclear receptor-mediated signaling pathways in hepatitis C virus patients with and without a history of alcohol drinking
    • Wu C., Gilroy R., Taylor R., Olyaee M., Abdulkarim B., Forster J., O'Neil M., Damjanov I., Wan Y. J., Alteration of hepatic nuclear receptor-mediated signaling pathways in hepatitis C virus patients with and without a history of alcohol drinking. Hepatology 2011 54 6 1966 1974
    • (2011) Hepatology , vol.54 , Issue.6 , pp. 1966-1974
    • Wu, C.1    Gilroy, R.2    Taylor, R.3    Olyaee, M.4    Abdulkarim, B.5    Forster, J.6    O'Neil, M.7    Damjanov, I.8    Wan, Y.J.9
  • 90
    • 80054728029 scopus 로고    scopus 로고
    • Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism
    • 2-s2.0-79960608394 10.1016/j.jhep.2011.02.011
    • Goldwasser J., Cohen P. Y., Lin W., Kitsberg D., Balaguer P., Polyak S. J., Chung R. T., Yarmush M. L., Nahmias Y., Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. Journal of Hepatology 2011 55 5 963 971 2-s2.0-79960608394 10.1016/j.jhep.2011.02.011
    • (2011) Journal of Hepatology , vol.55 , Issue.5 , pp. 963-971
    • Goldwasser, J.1    Cohen, P.Y.2    Lin, W.3    Kitsberg, D.4    Balaguer, P.5    Polyak, S.J.6    Chung, R.T.7    Yarmush, M.L.8    Nahmias, Y.9
  • 91
    • 30744432858 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α antagonism inhibits hepatitis C virus replication
    • DOI 10.1016/j.chembiol.2005.10.006, PII S1074552105003376
    • Rakic B., Sagan S. M., Noestheden M., Bélanger S., Nan X., Evans C. L., Xie X. S., Pezacki J. P., Peroxisome proliferator-activated receptor α antagonism inhibits hepatitis C virus replication. Chemistry and Biology 2006 13 1 23 30 2-s2.0-30744432858 10.1016/j.chembiol.2005.10.006 (Pubitemid 43099921)
    • (2006) Chemistry and Biology , vol.13 , Issue.1 , pp. 23-30
    • Rakic, B.1    Sagan, S.M.2    Noestheden, M.3    Belanger, S.4    Nan, X.5    Evans, C.L.6    Xie, X.S.7    Pezacki, J.P.8
  • 92
    • 67349255861 scopus 로고    scopus 로고
    • PPAR δ agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair
    • 2-s2.0-67349255861 10.1016/j.jhep.2009.01.021
    • Pang M., de la Monte S. M., Longato L., Tong M., He J., Chaudhry R., Duan K., Ouh J., Wands J. R., PPAR δ agonist attenuates alcohol-induced hepatic insulin resistance and improves liver injury and repair. Journal of Hepatology 2009 50 6 1192 1201 2-s2.0-67349255861 10.1016/j.jhep.2009.01.021
    • (2009) Journal of Hepatology , vol.50 , Issue.6 , pp. 1192-1201
    • Pang, M.1    De La Monte, S.M.2    Longato, L.3    Tong, M.4    He, J.5    Chaudhry, R.6    Duan, K.7    Ouh, J.8    Wands, J.R.9
  • 94
    • 20144389197 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells
    • DOI 10.1158/0008-5472.CAN-04-3037
    • Schaefer K. L., Wada K., Takahashi H., Matsuhashi N., Ohnishi S., Wolfe M. M., Turner J. R., Nakajima A., Borkan S. C., Saubermann L. J., Peroxisome proliferator-activated receptor γ inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells. Cancer Research 2005 65 6 2251 2259 2-s2.0-20144389197 10.1158/0008-5472.CAN-04- 3037 (Pubitemid 40490134)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2251-2259
    • Schaefer, K.L.1    Wada, K.2    Takahashi, H.3    Matsuhashi, N.4    Ohnishi, S.5    Wolfe, M.M.6    Turner, J.R.7    Nakajima, A.8    Borkan, S.C.9    Saubermann, L.J.10
  • 95
    • 0037110628 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligand troglitazone induces cell cycle arrest and apoptosis of hepatocellular carcinoma cell lines
    • DOI 10.1002/cncr.10906
    • Yoshizawa K., Cioca D. P., Kawa S., Tanaka E., Kiyosawa K., Peroxisome proliferator-activated receptor γ ligand troglitazone induces cell cycle arrest and apoptosis of hepatocellular carcinoma cell lines. Cancer 2002 95 10 2243 2251 2-s2.0-0037110628 10.1002/cncr.10906 (Pubitemid 35253388)
    • (2002) Cancer , vol.95 , Issue.10 , pp. 2243-2251
    • Yoshizawa, K.1    Cioca, D.P.2    Kawa, S.3    Tanaka, E.4    Kiyosawa, K.5
  • 96
    • 70349139683 scopus 로고    scopus 로고
    • Rosiglitazone sensitizes hepatocellular carcinoma cell lines to 5-fluorouracil antitumor activity through activation of the PPAR γ signaling pathway
    • 2-s2.0-70349139683 10.1038/aps.2009.119
    • Cao L. Q., Wang X. L., Wang Q., Xue P., Jiao X. Y., Peng H. P., Lu H. W., Zheng Q., Chen X. L., Huang X. H., Fu X. H., Chen J. S., Rosiglitazone sensitizes hepatocellular carcinoma cell lines to 5-fluorouracil antitumor activity through activation of the PPAR γ signaling pathway. Acta Pharmacologica Sinica 2009 30 9 1316 1322 2-s2.0-70349139683 10.1038/aps.2009.119
    • (2009) Acta Pharmacologica Sinica , vol.30 , Issue.9 , pp. 1316-1322
    • Cao, L.Q.1    Wang, X.L.2    Wang, Q.3    Xue, P.4    Jiao, X.Y.5    Peng, H.P.6    Lu, H.W.7    Zheng, Q.8    Chen, X.L.9    Huang, X.H.10    Fu, X.H.11    Chen, J.S.12
  • 97
    • 75149166058 scopus 로고    scopus 로고
    • PPAR γ /PGC-1 α pathway in E-cadherin expression and motility of HepG2 cells
    • 2-s2.0-75149166058
    • Lee H. J., Su Y., Yin P. H., Lee H. C., Chi C. W., PPAR γ /PGC-1 α pathway in E-cadherin expression and motility of HepG2 cells. Anticancer Research 2009 29 12 5057 5063 2-s2.0-75149166058
    • (2009) Anticancer Research , vol.29 , Issue.12 , pp. 5057-5063
    • Lee, H.J.1    Su, Y.2    Yin, P.H.3    Lee, H.C.4    Chi, C.W.5
  • 98
    • 74549184686 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor γ ligands, pioglitazone and 15-deoxy-Δ(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells
    • 2-s2.0-74549184686 10.3892/ijo-00000493
    • Shim J., Kim B. H., Kim Y. I., Kim K. Y., Hwangbo Y., Jang J. Y., Dong S. H., Kim H. J., Chang Y. W., Chang R., The peroxisome proliferator-activated receptor γ ligands, pioglitazone and 15-deoxy-Δ(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells. International Journal of Oncology 2010 36 1 223 231 2-s2.0-74549184686 10.3892/ijo-00000493
    • (2010) International Journal of Oncology , vol.36 , Issue.1 , pp. 223-231
    • Shim, J.1    Kim, B.H.2    Kim, Y.I.3    Kim, K.Y.4    Hwangbo, Y.5    Jang, J.Y.6    Dong, S.H.7    Kim, H.J.8    Chang, Y.W.9    Chang, R.10
  • 99
    • 34447251654 scopus 로고    scopus 로고
    • The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver
    • DOI 10.1016/j.ejca.2007.05.005, PII S0959804907003760
    • Borbath I., Leclercq I., Moulin P., Sempoux C., Horsmans Y., The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver. European Journal of Cancer 2007 43 11 1755 1763 2-s2.0-34447251654 10.1016/j.ejca.2007.05.005 (Pubitemid 47042376)
    • (2007) European Journal of Cancer , vol.43 , Issue.11 , pp. 1755-1763
    • Borbath, I.1    Leclercq, I.2    Moulin, P.3    Sempoux, C.4    Horsmans, Y.5
  • 100
    • 33644792520 scopus 로고    scopus 로고
    • Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo
    • DOI 10.1002/hep.20994
    • Yu J., Qiao L., Zimmermann L., Ebert M. P. A., Zhang H., Lin W., Röcken C., Malfertheiner P., Farrell G. C., Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo. Hepatology 2006 43 1 134 143 2-s2.0-33644792520 10.1002/hep.20994 (Pubitemid 43733600)
    • (2006) Hepatology , vol.43 , Issue.1 , pp. 134-143
    • Yu, J.1    Qiao, L.2    Zimmermann, L.3    Ebert, M.P.A.4    Zhang, H.5    Lin, W.6    Rocken, C.7    Malfertheiner, P.8    Farrell, G.C.9
  • 101
    • 48249136165 scopus 로고    scopus 로고
    • Overexpression of Jab1 in hepatocellular carcinoma and its inhibition by peroxisome proliferator-activated receptor γ ligands in vitro and in vivo
    • 2-s2.0-48249136165 10.1158/1078-0432.CCR-07-5040
    • Hsu M. C., Huang C. C., Chang H. C., Hu T. H., Hung W. C., Overexpression of Jab1 in hepatocellular carcinoma and its inhibition by peroxisome proliferator-activated receptor γ ligands in vitro and in vivo. Clinical Cancer Research 2008 14 13 4045 4052 2-s2.0-48249136165 10.1158/1078-0432.CCR- 07-5040
    • (2008) Clinical Cancer Research , vol.14 , Issue.13 , pp. 4045-4052
    • Hsu, M.C.1    Huang, C.C.2    Chang, H.C.3    Hu, T.H.4    Hung, W.C.5
  • 102
    • 34250163202 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation
    • DOI 10.1128/MCB.00317-07
    • Shah Y. M., Morimura K., Yang Q., Tanabe T., Takagi M., Gonzalez F. J., Peroxisome proliferator-activated receptor α regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Molecular and Cellular Biology 2007 27 12 4238 4247 2-s2.0-34250163202 10.1128/MCB.00317-07 (Pubitemid 46906549)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.12 , pp. 4238-4247
    • Shah, Y.M.1    Morimura, K.2    Yang, Q.3    Tanabe, T.4    Takagi, M.5    Gonzalez, F.J.6
  • 103
    • 40049088000 scopus 로고    scopus 로고
    • PPAR α: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators
    • 2-s2.0-40049088000 10.1016/j.tox.2007.09.030
    • Gonzalez F. J., Shah Y. M., PPAR α: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators. Toxicology 2008 246 1 2 8 2-s2.0-40049088000 10.1016/j.tox.2007.09.030
    • (2008) Toxicology , vol.246 , Issue.1 , pp. 2-8
    • Gonzalez, F.J.1    Shah, Y.M.2
  • 104
    • 84857641358 scopus 로고    scopus 로고
    • The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention
    • Peters J. M., Shah Y. M., Gonzalez F. J., The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nature Reviews 2012 12 3 181 195
    • (2012) Nature Reviews , vol.12 , Issue.3 , pp. 181-195
    • Peters, J.M.1    Shah, Y.M.2    Gonzalez, F.J.3
  • 105
    • 0031418657 scopus 로고    scopus 로고
    • Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
    • DOI 10.1093/carcin/18.11.2029
    • Peters J. M., Cattley R. C., Gonzalez F. J., Role of PPAR α in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis 1997 18 11 2029 2033 2-s2.0-0031418657 10.1093/carcin/18.11.2029 (Pubitemid 28134725)
    • (1997) Carcinogenesis , vol.18 , Issue.11 , pp. 2029-2033
    • Peters, J.M.1    Cattley, R.C.2    Gonzalez, F.J.3
  • 106
    • 13444311098 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor-α (PPARα) in bezafibrate-induced hepatocarcinogenesis and cholestasis
    • DOI 10.1093/carcin/bgh285
    • Hays T., Rusyn I., Burns A. M., Kennett M. J., Ward J. M., Gonzalez F. J., Peters J. M., Role of peroxisome proliferator-activated receptor- α (PPAR α) in bezafibrate-induced hepatocarcinogenesis and cholestasis. Carcinogenesis 2005 26 1 219 227 2-s2.0-13444311098 10.1093/carcin/bgh285 (Pubitemid 40207717)
    • (2005) Carcinogenesis , vol.26 , Issue.1 , pp. 219-227
    • Hays, T.1    Rusyn, I.2    Burns, A.M.3    Kennett, M.J.4    Ward, J.M.5    Gonzalez, F.J.6    Peters, J.M.7
  • 107
    • 0011446750 scopus 로고    scopus 로고
    • Enhanced hepatocarcinogenicity due to agonists of peroxisome proliferator-activated receptors in senescent rats: Role of peroxisome proliferation, cell proliferation, and apoptosis
    • 2-s2.0-0011446750
    • Youssef J., Badr M., Enhanced hepatocarcinogenicity due to agonists of peroxisome proliferator-activated receptors in senescent rats: role of peroxisome proliferation, cell proliferation, and apoptosis. TheScientificWorldJournal 2002 2 1491 1500 2-s2.0-0011446750
    • (2002) TheScientificWorldJournal , vol.2 , pp. 1491-1500
    • Youssef, J.1    Badr, M.2
  • 108
    • 56449124307 scopus 로고    scopus 로고
    • Evaluation of the role of peroxisome proliferator-activated receptor α (PPAR α) in mouse liver tumor induction by trichloroethylene and metabolites
    • 2-s2.0-56449124307 10.1080/10408440802209796
    • Corton J. C., Evaluation of the role of peroxisome proliferator-activated receptor α (PPAR α) in mouse liver tumor induction by trichloroethylene and metabolites. Critical Reviews in Toxicology 2008 38 10 857 875 2-s2.0-56449124307 10.1080/10408440802209796
    • (2008) Critical Reviews in Toxicology , vol.38 , Issue.10 , pp. 857-875
    • Corton, J.C.1
  • 109
    • 36749083957 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor α in transgenic mice: Implications for HCV-associated hepatocarcinogenesis
    • DOI 10.1002/ijc.23056
    • Tanaka N., Moriya K., Kiyosawa K., Koike K., Aoyama T., Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor α in transgenic mice: implications for HCV-associated hepatocarcinogenesis. International Journal of Cancer 2008 122 1 124 131 2-s2.0-36749083957 10.1002/ijc.23056 (Pubitemid 350209986)
    • (2008) International Journal of Cancer , vol.122 , Issue.1 , pp. 124-131
    • Tanaka, N.1    Moriya, K.2    Kiyosawa, K.3    Koike, K.4    Aoyama, T.5
  • 110
    • 38849184816 scopus 로고    scopus 로고
    • PPARα activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice
    • DOI 10.1172/JCI33594
    • Tanaka N., Moriya K., Kiyosawa K., Koike K., Gonzalez F. J., Aoyama T., PPAR α activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice. Journal of Clinical Investigation 2008 118 2 683 694 2-s2.0-38849184816 10.1172/JCI33594 (Pubitemid 351206557)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.2 , pp. 683-694
    • Tanaka, N.1    Moriya, K.2    Kiyosawa, K.3    Koike, K.4    Gonzalez, F.J.5    Aoyama, T.6
  • 111
    • 33646180263 scopus 로고    scopus 로고
    • Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor α to Wy-14,643-induced liver tumorigenesis
    • 2-s2.0-33646180263 10.1093/carcin/bgi329
    • Morimura K., Cheung C., Ward J. M., Reddy J. K., Gonzalez F. J., Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor α to Wy-14,643-induced liver tumorigenesis. Carcinogenesis 2006 27 5 1074 1080 2-s2.0-33646180263 10.1093/carcin/bgi329
    • (2006) Carcinogenesis , vol.27 , Issue.5 , pp. 1074-1080
    • Morimura, K.1    Cheung, C.2    Ward, J.M.3    Reddy, J.K.4    Gonzalez, F.J.5
  • 112
    • 2542635631 scopus 로고    scopus 로고
    • Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor α
    • DOI 10.1158/0008-5472.CAN-04-0322
    • Cheung C., Akiyama T. E., Ward J. M., Nicol C. J., Feigenbaum L., Vinson C., Gonzalez F. J., Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor α Cancer Research 2004 64 11 3849 3854 2-s2.0-2542635631 10.1158/0008-5472.CAN-04- 0322 (Pubitemid 38697295)
    • (2004) Cancer Research , vol.64 , Issue.11 , pp. 3849-3854
    • Cheung, C.1    Akiyama, T.E.2    Ward, J.M.3    Nicol, C.J.4    Feigenbaum, L.5    Vinson, C.6    Gonzalez, F.J.7
  • 113
    • 33846221464 scopus 로고    scopus 로고
    • 2 signaling pathways in human hepatocellular carcinoma cells
    • DOI 10.1158/0008-5472.CAN-06-1445
    • Xu L., Han C., Lim K., Wu T., Cross-talk between peroxisome proliferator-activated receptor δ and cytosolic phospholipase A(2) α /cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells. Cancer Research 2006 66 24 11859 11868 2-s2.0-33846221464 10.1158/0008-5472.CAN-06-1445 (Pubitemid 46094198)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11859-11868
    • Xu, L.1    Han, C.2    Lim, K.3    Wu, T.4
  • 114
    • 57649196331 scopus 로고    scopus 로고
    • Role of interleukin-6 in the control of DNA synthesis of hepatocytes: Involvement of PKC, p44/42 MAPKs, and PPAR δ
    • 2-s2.0-57649196331 10.1159/000185551
    • Suh H. N., Lee S. H., Lee M. Y., Lee Y. J., Lee J. H., Han H. J., Role of interleukin-6 in the control of DNA synthesis of hepatocytes: involvement of PKC, p44/42 MAPKs, and PPAR δ Cellular Physiology and Biochemistry 2008 22 5-6 673 684 2-s2.0-57649196331 10.1159/000185551
    • (2008) Cellular Physiology and Biochemistry , vol.22 , Issue.5-6 , pp. 673-684
    • Suh, H.N.1    Lee, S.H.2    Lee, M.Y.3    Lee, Y.J.4    Lee, J.H.5    Han, H.J.6
  • 115
    • 33750533592 scopus 로고    scopus 로고
    • Epigenetic regulation of nuclear steroid receptors
    • DOI 10.1016/j.bcp.2006.05.024, PII S0006295206003285, Cell Signalling, Transcription and Translation as Therapeutic Tergets
    • Leader J. E., Wang C., Fu M., Pestell R. G., Epigenetic regulation of nuclear steroid receptors. Biochemical Pharmacology 2006 72 11 1589 1596 2-s2.0-33750533592 10.1016/j.bcp.2006.05.024 (Pubitemid 44666731)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.11 , pp. 1589-1596
    • Leader, J.E.1    Wang, C.2    Fu, M.3    Pestell, R.G.4
  • 116
    • 75149141045 scopus 로고    scopus 로고
    • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
    • 2-s2.0-75149141045 10.1053/j.gastro.2009.10.002
    • Mann J., Chu D. C. K., Maxwell A., Oakley F., Zhu N. L., Tsukamoto H., Mann D. A., MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology 2010 138 2 705.e4 714.e4 2-s2.0-75149141045 10.1053/j.gastro.2009.10.002
    • (2010) Gastroenterology , vol.138 , Issue.2
    • Mann, J.1    Chu, D.C.K.2    Maxwell, A.3    Oakley, F.4    Zhu, N.L.5    Tsukamoto, H.6    Mann, D.A.7
  • 117
    • 62749188230 scopus 로고    scopus 로고
    • Egr-1 is involved in the inhibitory effect of leptin on PPAR γ expression in hepatic stellate cell in vitro
    • 2-s2.0-62749188230 10.1016/j.lfs.2009.01.018
    • Zhou Y., Jia X., Zhou M., Liu J., Egr-1 is involved in the inhibitory effect of leptin on PPAR γ expression in hepatic stellate cell in vitro. Life Sciences 2009 84 15-16 544 551 2-s2.0-62749188230 10.1016/j.lfs.2009.01.018
    • (2009) Life Sciences , vol.84 , Issue.15-16 , pp. 544-551
    • Zhou, Y.1    Jia, X.2    Zhou, M.3    Liu, J.4
  • 118
    • 78049260100 scopus 로고    scopus 로고
    • Chromatin accessibility and transcription factor binding at the PPAR γ 2 promoter during adipogenesis is protein kinase A-dependent
    • 2-s2.0-78049260100 10.1002/jcp.22308
    • Xiao H., LeBlanc S. E., Wu Q., Konda S., Salma N., Marfella C. G., Ohkawa Y., Imbalzano A. N., Chromatin accessibility and transcription factor binding at the PPAR γ 2 promoter during adipogenesis is protein kinase A-dependent. Journal of Cellular Physiology 2011 226 1 86 93 2-s2.0-78049260100 10.1002/jcp.22308
    • (2011) Journal of Cellular Physiology , vol.226 , Issue.1 , pp. 86-93
    • Xiao, H.1    Leblanc, S.E.2    Wu, Q.3    Konda, S.4    Salma, N.5    Marfella, C.G.6    Ohkawa, Y.7    Imbalzano, A.N.8
  • 119
    • 84859157159 scopus 로고    scopus 로고
    • Carbonic anhydrase III regulates peroxisome proliferator-activated receptor-gamma2
    • 2-s2.0-84859157159 10.1016/j.yexcr.2012.02.011
    • Mitterberger M. C., Kim G., Rostek U., Levine R. L., Zwerschke W., Carbonic anhydrase III regulates peroxisome proliferator-activated receptor-gamma2. Experimental Cell Research 2012 318 8 877 886 2-s2.0-84859157159 10.1016/j.yexcr.2012.02.011
    • (2012) Experimental Cell Research , vol.318 , Issue.8 , pp. 877-886
    • Mitterberger, M.C.1    Kim, G.2    Rostek, U.3    Levine, R.L.4    Zwerschke, W.5
  • 120
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • DOI 10.1016/j.cmet.2006.07.001, PII S1550413106002403
    • Farmer S. R., Transcriptional control of adipocyte formation. Cell Metabolism 2006 4 4 263 273 2-s2.0-33748942837 10.1016/j.cmet.2006.07.001 (Pubitemid 44430910)
    • (2006) Cell Metabolism , vol.4 , Issue.4 , pp. 263-273
    • Farmer, S.R.1
  • 121
    • 77956259307 scopus 로고    scopus 로고
    • β, β -carotene decreases peroxisome proliferator receptor γ activity and reduces lipid storage capacity of adipocytes in a β, β -carotene oxygenase 1-dependent manner
    • 2-s2.0-77956259307 10.1074/jbc.M110.132571
    • Lobo G. P., Amengual J., Li H. N. M., Golczak M., Bonet M. L., Palczewski K., Von Lintig J., β β -carotene decreases peroxisome proliferator receptor γ activity and reduces lipid storage capacity of adipocytes in a β β -carotene oxygenase 1-dependent manner. Journal of Biological Chemistry 2010 285 36 27891 27899 2-s2.0-77956259307 10.1074/jbc.M110.132571
    • (2010) Journal of Biological Chemistry , vol.285 , Issue.36 , pp. 27891-27899
    • Lobo, G.P.1    Amengual, J.2    Li, H.N.M.3    Golczak, M.4    Bonet, M.L.5    Palczewski, K.6    Von Lintig, J.7
  • 122
    • 84856487109 scopus 로고    scopus 로고
    • The story so far: Post-translational regulation of peroxisome proliferator-activated receptors by ubiquitination and SUMOylation
    • Wadosky K. M., Willis M. S., The story so far: post-translational regulation of peroxisome proliferator-activated receptors by ubiquitination and SUMOylation. American Journal of Physiology 2012 302 3 H515 H526
    • (2012) American Journal of Physiology , vol.302 , Issue.3
    • Wadosky, K.M.1    Willis, M.S.2
  • 123
    • 0033537827 scopus 로고    scopus 로고
    • Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor by phosphorylation of a ligand-independent trans-activating domain
    • DOI 10.1074/jbc.274.15.10505
    • Juge-Aubry C. E., Hammar E., Siegrist-Kaiser C., Pernin A., Takeshita A., Chin W. W., Burger A. G., Meier C. A., Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor by phosphorylation of a ligand-independent trans-activating domain. Journal of Biological Chemistry 1999 274 15 10505 10510 2-s2.0-0033537827 10.1074/jbc.274.15.10505 (Pubitemid 29180929)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.15 , pp. 10505-10510
    • Juge-Aubry, C.E.1    Hammar, E.2    Siegrist-Kaiser, C.3    Pernin, A.4    Takeshita, A.5    Chin, W.W.6    Burger, A.G.7    Meier, C.A.8
  • 124
    • 0042405041 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARS): Regulators of gene expression in heart and skeletal muscle
    • DOI 10.1046/j.1365-201X.2003.01161.x
    • Gilde A. J., Van Bilsen M., Peroxisome proliferator-activated receptors (PPARS): regulators of gene expression in heart and skeletal muscle. Acta Physiologica Scandinavica 2003 178 4 425 434 2-s2.0-0042405041 10.1046/j.1365-201X.2003.01161.x (Pubitemid 36960434)
    • (2003) Acta Physiologica Scandinavica , vol.178 , Issue.4 , pp. 425-434
    • Gilde, A.J.1    Van Bilsen, M.2
  • 125
    • 34547604561 scopus 로고    scopus 로고
    • Transcription coactivators for peroxisome proliferator-activated receptors
    • DOI 10.1016/j.bbalip.2007.01.008, PII S138819810700011X
    • Yu S., Reddy J. K., Transcription coactivators for peroxisome proliferator-activated receptors. Biochimica et Biophysica Acta 2007 1771 8 936 951 2-s2.0-34547604561 10.1016/j.bbalip.2007.01.008 (Pubitemid 47198542)
    • (2007) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1771 , Issue.8 , pp. 936-951
    • Yu, S.1    Reddy, J.K.2
  • 126
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
    • DOI 10.1016/j.molcel.2007.06.017, PII S1097276507004078
    • Grimson A., Farh K. K. H., Johnston W. K., Garrett-Engele P., Lim L. P., Bartel D. P., MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Molecular Cell 2007 27 1 91 105 2-s2.0-34250805982 10.1016/j.molcel.2007.06.017 (Pubitemid 46991392)
    • (2007) Molecular Cell , vol.27 , Issue.1 , pp. 91-105
    • Grimson, A.1    Farh, K.K.-H.2    Johnston, W.K.3    Garrett-Engele, P.4    Lim, L.P.5    Bartel, D.P.6
  • 127
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • DOI 10.1016/0092-8674(93)90529-Y
    • Lee R. C., Feinbaum R. L., Ambros V., The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993 75 5 843 854 2-s2.0-0027751663 10.1016/0092-8674(93)90529-Y (Pubitemid 24014542)
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 128
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • 2-s2.0-38349169664 10.1038/nrg2290
    • Filipowicz W., Bhattacharyya S. N., Sonenberg N., Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nature Reviews Genetics 2008 9 2 102 114 2-s2.0-38349169664 10.1038/nrg2290
    • (2008) Nature Reviews Genetics , vol.9 , Issue.2 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 130
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • DOI 10.1038/sj.emboj.7600385
    • Lee Y., Kim M., Han J., Yeom K. H., Lee S., Baek S. H., Kim V. N., MicroRNA genes are transcribed by RNA polymerase II. The EMBO Journal 2004 23 20 4051 4060 2-s2.0-8144225486 10.1038/sj.emboj.7600385 (Pubitemid 39472426)
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.-H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 131
    • 77954385729 scopus 로고    scopus 로고
    • The complexities of microRNA regulation: Mirandering around the rules
    • 2-s2.0-77954385729 10.1016/j.biocel.2009.09.016
    • Breving K., Esquela-Kerscher A., The complexities of microRNA regulation: mirandering around the rules. International Journal of Biochemistry and Cell Biology 2010 42 8 1316 1329 2-s2.0-77954385729 10.1016/j.biocel.2009.09.016
    • (2010) International Journal of Biochemistry and Cell Biology , vol.42 , Issue.8 , pp. 1316-1329
    • Breving, K.1    Esquela-Kerscher, A.2
  • 132
    • 23044502585 scopus 로고    scopus 로고
    • Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences
    • DOI 10.1074/jbc.M504714200
    • Zeng Y., Cullen B. R., Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. Journal of Biological Chemistry 2005 280 30 27595 27603 2-s2.0-23044502585 10.1074/jbc.M504714200 (Pubitemid 41076871)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.30 , pp. 27595-27603
    • Zeng, Y.1    Cullen, B.R.2
  • 133
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, Biogenesis, Mechanism, and Function
    • DOI 10.1016/S0092-8674(04)00045-5
    • Bartel D. P., MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004 116 2 281 297 2-s2.0-0347444723 10.1016/S0092-8674(04)00045-5 (Pubitemid 38167318)
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 134
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • DOI 10.1101/gad.1158803
    • Yi R., Qin Y., Macara I. G., Cullen B. R., Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes and Development 2003 17 24 3011 3016 2-s2.0-0347361541 10.1101/gad.1158803 (Pubitemid 38040764)
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 135
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear Export of MicroRNA Precursors
    • DOI 10.1126/science.1090599
    • Lund E., Güttinger S., Calado A., Dahlberg J. E., Kutay U., Nuclear export of microRNA precursors. Science 2004 303 5654 95 98 2-s2.0-0347988235 10.1126/science.1090599 (Pubitemid 38055779)
    • (2004) Science , vol.303 , Issue.5654 , pp. 95-98
    • Lund, E.1    Guttinger, S.2    Calado, A.3    Dahlberg, J.E.4    Kutay, U.5
  • 136
    • 79952632135 scopus 로고    scopus 로고
    • A precursor microRNA in a cancer cell nucleus: Get me out of here!
    • Melo S. A., Esteller M., A precursor microRNA in a cancer cell nucleus: get me out of here! Cell Cycle 2011 10 6 922 925
    • (2011) Cell Cycle , vol.10 , Issue.6 , pp. 922-925
    • Melo, S.A.1    Esteller, M.2
  • 137
    • 3142613181 scopus 로고    scopus 로고
    • Single processing center models for human Dicer and bacterial RNase III
    • DOI 10.1016/j.cell.2004.06.017, PII S009286740400618X
    • Zhang H., Kolb F. A., Jaskiewicz L., Westhof E., Filipowicz W., Single processing center models for human Dicer and bacterial RNase III. Cell 2004 118 1 57 68 2-s2.0-3142613181 10.1016/j.cell.2004.06.017 (Pubitemid 38902814)
    • (2004) Cell , vol.118 , Issue.1 , pp. 57-68
    • Zhang, H.1    Kolb, F.A.2    Jaskiewicz, L.3    Westhof, E.4    Filipowicz, W.5
  • 138
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • DOI 10.1016/j.cell.2005.10.022, PII S0092867405011098
    • Gregory R. I., Chendrimada T. P., Cooch N., Shiekhattar R., Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 2005 123 4 631 640 2-s2.0-27744537851 10.1016/j.cell.2005.10.022 (Pubitemid 41608466)
    • (2005) Cell , vol.123 , Issue.4 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 139
    • 69949127421 scopus 로고    scopus 로고
    • Structural determinants of miRNAs for RISC loading and slicer-independent unwinding
    • 2-s2.0-69949127421 10.1038/nsmb.1630
    • Kawamata T., Seitz H., Tomari Y., Structural determinants of miRNAs for RISC loading and slicer-independent unwinding. Nature Structural and Molecular Biology 2009 16 9 953 960 2-s2.0-69949127421 10.1038/nsmb.1630
    • (2009) Nature Structural and Molecular Biology , vol.16 , Issue.9 , pp. 953-960
    • Kawamata, T.1    Seitz, H.2    Tomari, Y.3
  • 140
    • 79951865331 scopus 로고    scopus 로고
    • Analysis of microRNA knockouts in mice
    • R2 2-s2.0-79951865331
    • Park C. Y., Choi Y. S., McManus M. T., Analysis of microRNA knockouts in mice. Human Molecular Genetics 2010 19 R2 R169 R175 2-s2.0-79951865331
    • (2010) Human Molecular Genetics , vol.19
    • Park, C.Y.1    Choi, Y.S.2    McManus, M.T.3
  • 141
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • 2-s2.0-49949116902 10.1038/nature07242
    • Baek D., Villén J., Shin C., Camargo F. D., Gygi S. P., Bartel D. P., The impact of microRNAs on protein output. Nature 2008 455 7209 64 71 2-s2.0-49949116902 10.1038/nature07242
    • (2008) Nature , vol.455 , Issue.7209 , pp. 64-71
    • Baek, D.1    Villén, J.2    Shin, C.3    Camargo, F.D.4    Gygi, S.P.5    Bartel, D.P.6
  • 143
    • 79551473619 scopus 로고    scopus 로고
    • Tissue-specific regulation of mouse microRNA genes in endoderm-derived tissues
    • 2-s2.0-79551473619 10.1093/nar/gkq782
    • Gao Y., Schug J., McKenna L. B., Le Lay J., Kaestner K. H., Greenbaum L. E., Tissue-specific regulation of mouse microRNA genes in endoderm-derived tissues. Nucleic Acids Research 2011 39 2 454 463 2-s2.0-79551473619 10.1093/nar/gkq782
    • (2011) Nucleic Acids Research , vol.39 , Issue.2 , pp. 454-463
    • Gao, Y.1    Schug, J.2    McKenna, L.B.3    Le Lay, J.4    Kaestner, K.H.5    Greenbaum, L.E.6
  • 144
    • 84855244103 scopus 로고    scopus 로고
    • MicroRNA therapeutics in cardiovascular medicine
    • Thum T., MicroRNA therapeutics in cardiovascular medicine. EMBO Molecular Medicine 2012 4 1 3 14
    • (2012) EMBO Molecular Medicine , vol.4 , Issue.1 , pp. 3-14
    • Thum, T.1
  • 145
    • 80052102044 scopus 로고    scopus 로고
    • Diabetes complications: The microRNA perspective
    • 2-s2.0-80052102044 10.2337/db11-0082
    • Kantharidis P., Wang B., Carew R. M., Lan H. Y., Diabetes complications: the microRNA perspective. Diabetes 2011 60 7 1832 1837 2-s2.0-80052102044 10.2337/db11-0082
    • (2011) Diabetes , vol.60 , Issue.7 , pp. 1832-1837
    • Kantharidis, P.1    Wang, B.2    Carew, R.M.3    Lan, H.Y.4
  • 147
    • 77952675535 scopus 로고    scopus 로고
    • MicroRNAs and deregulated gene expression networks in neurodegeneration
    • 2-s2.0-77952675535 10.1016/j.brainres.2010.03.106
    • Sonntag K. C., MicroRNAs and deregulated gene expression networks in neurodegeneration. Brain Research 2010 1338 48 57 2-s2.0-77952675535 10.1016/j.brainres.2010.03.106
    • (2010) Brain Research , vol.1338 , pp. 48-57
    • Sonntag, K.C.1
  • 148
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • 2-s2.0-75649139134 10.1038/nri2708
    • O'Connell R. M., Rao D. S., Chaudhuri A. A., Baltimore D., Physiological and pathological roles for microRNAs in the immune system. Nature Reviews Immunology 2010 10 2 111 122 2-s2.0-75649139134 10.1038/nri2708
    • (2010) Nature Reviews Immunology , vol.10 , Issue.2 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 149
    • 77956339881 scopus 로고    scopus 로고
    • OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
    • 2-s2.0-77956339881 10.1038/nature09284
    • Medina P. P., Nolde M., Slack F. J., OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 2010 467 7311 86 90 2-s2.0-77956339881 10.1038/nature09284
    • (2010) Nature , vol.467 , Issue.7311 , pp. 86-90
    • Medina, P.P.1    Nolde, M.2    Slack, F.J.3
  • 151
    • 77957954445 scopus 로고    scopus 로고
    • Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development
    • 2-s2.0-77957954445 10.1002/hep.23818
    • Xu H., He J. H., Xiao Z. D., Zhang Q. Q., Chen Y. Q., Zhou H., Qu L. H., Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development. Hepatology 2010 52 4 1431 1442 2-s2.0-77957954445 10.1002/hep.23818
    • (2010) Hepatology , vol.52 , Issue.4 , pp. 1431-1442
    • Xu, H.1    He, J.H.2    Xiao, Z.D.3    Zhang, Q.Q.4    Chen, Y.Q.5    Zhou, H.6    Qu, L.H.7
  • 152
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • DOI 10.1038/nature04303
    • Krützfeldt J., Rajewsky N., Braich R., Rajeev K. G., Tuschl T., Manoharan M., Stoffel M., Silencing of microRNAs in vivo with antagomirs Nature 2005 438 7068 685 689 2-s2.0-28444469246 10.1038/nature04303 (Pubitemid 41740580)
    • (2005) Nature , vol.438 , Issue.7068 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3    Rajeev, K.G.4    Tuschl, T.5    Manoharan, M.6    Stoffel, M.7
  • 155
    • 80655147912 scopus 로고    scopus 로고
    • The parallel universe: MicroRNAs and their role in chronic hepatitis, liver tissue damage and hepatocarcinogenesis
    • w13287
    • Haybaeck J., Zeller N., Heikenwalder M., The parallel universe: microRNAs and their role in chronic hepatitis, liver tissue damage and hepatocarcinogenesis. Swiss Medical Weekly 2011 141 w13287
    • (2011) Swiss Medical Weekly , vol.141
    • Haybaeck, J.1    Zeller, N.2    Heikenwalder, M.3
  • 157
    • 84855826136 scopus 로고    scopus 로고
    • Serum microRNA-122 levels in different groups of patients with chronic hepatitis B virus infection
    • 2-s2.0-84855826136 10.1111/j.1365-2893.2011.01536.x
    • Waidmann O., Bihrer V., Pleli T., Farnik H., Berger A., Zeuzem S., Kronenberger B., Piiper A., Serum microRNA-122 levels in different groups of patients with chronic hepatitis B virus infection. Journal of Viral Hepatitis 2012 19 2 e58 e65 2-s2.0-84855826136 10.1111/j.1365-2893.2011.01536.x
    • (2012) Journal of Viral Hepatitis , vol.19 , Issue.2
    • Waidmann, O.1    Bihrer, V.2    Pleli, T.3    Farnik, H.4    Berger, A.5    Zeuzem, S.6    Kronenberger, B.7    Piiper, A.8
  • 159
    • 77951219188 scopus 로고    scopus 로고
    • MicroRNAs and the regulation of fibrosis
    • 2-s2.0-77951219188 10.1111/j.1742-4658.2010.07632.x
    • Jiang X., Tsitsiou E., Herrick S. E., Lindsay M. A., MicroRNAs and the regulation of fibrosis. FEBS Journal 2010 277 9 2015 2021 2-s2.0-77951219188 10.1111/j.1742-4658.2010.07632.x
    • (2010) FEBS Journal , vol.277 , Issue.9 , pp. 2015-2021
    • Jiang, X.1    Tsitsiou, E.2    Herrick, S.E.3    Lindsay, M.A.4
  • 160
    • 84857979740 scopus 로고    scopus 로고
    • Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy
    • 2-s2.0-84857979740 10.1681/ASN.2011050485
    • Putta S., Lanting L., Sun G., Lawson G., Kato M., Natarajan R., Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy. Journal of the American Society of Nephrology 2012 23 3 458 469 2-s2.0-84857979740 10.1681/ASN.2011050485
    • (2012) Journal of the American Society of Nephrology , vol.23 , Issue.3 , pp. 458-469
    • Putta, S.1    Lanting, L.2    Sun, G.3    Lawson, G.4    Kato, M.5    Natarajan, R.6
  • 161
    • 46249083024 scopus 로고    scopus 로고
    • MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations
    • DOI 10.1002/hep.22256
    • Ladeiro Y., Couchy G., Balabaud C., Bioulac-Sage P., Pelletier L., Rebouissou S., Zucman-Rossi J., MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology 2008 47 6 1955 1963 2-s2.0-46249083024 10.1002/hep.22256 (Pubitemid 351952843)
    • (2008) Hepatology , vol.47 , Issue.6 , pp. 1955-1963
    • Ladeiro, Y.1    Couchy, G.2    Balabaud, C.3    Bioulac-Sage, P.4    Pelletier, L.5    Rebouissou, S.6    Zucman-Rossi, J.7
  • 162
    • 45149128115 scopus 로고    scopus 로고
    • Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target
    • 2-s2.0-45149128115 10.1074/jbc.M707629200
    • Wang Y., Lee A. T. C., Ma J. Z. I., Wang J., Ren J., Yang Y., Tantoso E., Li K. B., Ooi L. L. P. J., Tan P., Lee C. G. L., Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. Journal of Biological Chemistry 2008 283 19 13205 13215 2-s2.0-45149128115 10.1074/jbc.M707629200
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.19 , pp. 13205-13215
    • Wang, Y.1    Lee, A.T.C.2    Ma, J.Z.I.3    Wang, J.4    Ren, J.5    Yang, Y.6    Tantoso, E.7    Li, K.B.8    Ooi, L.L.P.J.9    Tan, P.10    Lee, C.G.L.11
  • 163
    • 73449136157 scopus 로고    scopus 로고
    • Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR- α expression, a novel mechanism for the pathogenesis of NAFLD
    • 2-s2.0-73449136157 10.1111/j.1440-1746.2009.05949.x
    • Zheng L., Lv G. C., Sheng J., Yang Y. D., Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR- α expression, a novel mechanism for the pathogenesis of NAFLD. Journal of Gastroenterology and Hepatology 2010 25 1 156 163 2-s2.0-73449136157 10.1111/j.1440-1746.2009.05949.x
    • (2010) Journal of Gastroenterology and Hepatology , vol.25 , Issue.1 , pp. 156-163
    • Zheng, L.1    Lv, G.C.2    Sheng, J.3    Yang, Y.D.4
  • 167
    • 76349089521 scopus 로고    scopus 로고
    • MiR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression
    • 2-s2.0-76349089521 10.1016/j.bbrc.2010.01.012
    • Kim S. Y., Kim A. Y., Lee H. W., Son Y. H., Lee G. Y., Lee J.-W., Lee Y. S., Kim J. B., MiR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression. Biochemical and Biophysical Research Communications 2010 392 3 323 328 2-s2.0-76349089521 10.1016/j.bbrc.2010.01.012
    • (2010) Biochemical and Biophysical Research Communications , vol.392 , Issue.3 , pp. 323-328
    • Kim, S.Y.1    Kim, A.Y.2    Lee, H.W.3    Son, Y.H.4    Lee, G.Y.5    Lee, J.-W.6    Lee, Y.S.7    Kim, J.B.8
  • 171
    • 77951219696 scopus 로고    scopus 로고
    • MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor γ (PPAR γ) mRNA destabilization
    • 2-s2.0-77951219696 10.1074/jbc.M109.066399
    • Jennewein C., Von Knethen A., Schmid T., Brüne B., MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor γ (PPAR γ) mRNA destabilization. Journal of Biological Chemistry 2010 285 16 11846 11853 2-s2.0-77951219696 10.1074/jbc.M109.066399
    • (2010) Journal of Biological Chemistry , vol.285 , Issue.16 , pp. 11846-11853
    • Jennewein, C.1    Von Knethen, A.2    Schmid, T.3    Brüne, B.4
  • 172
    • 56649084972 scopus 로고    scopus 로고
    • Integrative MicroRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks
    • 2-s2.0-56649084972 10.1371/journal.pone.0003740 e3740
    • Iliopoulos D., Malizos K. N., Oikonomou P., Tsezou A., Integrative MicroRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks. PLoS ONE 2008 3 11 2-s2.0-56649084972 10.1371/journal.pone.0003740 e3740
    • (2008) PLoS ONE , vol.3 , Issue.11
    • Iliopoulos, D.1    Malizos, K.N.2    Oikonomou, P.3    Tsezou, A.4
  • 173
    • 79959973595 scopus 로고    scopus 로고
    • MicroRNA-21 targets peroxisome proliferators-activated receptor- α in an autoregulatory loop to modulate flow-induced endothelial inflammation
    • 2-s2.0-79959973595 10.1073/pnas.1107052108
    • Zhou J., Wang K. C., Wu W., Subramaniam S., Shyy J. Y. J., Chiu J. J., Li J. Y. S., Chien S., MicroRNA-21 targets peroxisome proliferators-activated receptor- α in an autoregulatory loop to modulate flow-induced endothelial inflammation. Proceedings of the National Academy of Sciences of the United States of America 2011 108 25 10355 10360 2-s2.0-79959973595 10.1073/pnas.1107052108
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.108 , Issue.25 , pp. 10355-10360
    • Zhou, J.1    Wang, K.C.2    Wu, W.3    Subramaniam, S.4    Shyy, J.Y.J.5    Chiu, J.J.6    Li, J.Y.S.7    Chien, S.8
  • 174
    • 80855144808 scopus 로고    scopus 로고
    • MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin- resistant human colon cancer cells
    • 2-s2.0-80855144808 10.1016/j.febslet.2011.10.021
    • Tong J. L., Zhang C. P., Nie F., Xu X. T., Zhu M. M., Xiao S. D., Ran Z. H., MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin- resistant human colon cancer cells. FEBS Letters 2011 585 22 3560 3568 2-s2.0-80855144808 10.1016/j.febslet.2011.10.021
    • (2011) FEBS Letters , vol.585 , Issue.22 , pp. 3560-3568
    • Tong, J.L.1    Zhang, C.P.2    Nie, F.3    Xu, X.T.4    Zhu, M.M.5    Xiao, S.D.6    Ran, Z.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.