메뉴 건너뛰기




Volumn 19, Issue 17, 2013, Pages 3150-3160

Mitochondrial triglyceride transfer protein inhibition: New achievements in the treatment of dyslipidemias

Author keywords

Cardiovascular disease; Cholesterol; Fatty liver; Mitochondrial transfer protein

Indexed keywords

4' BROMO 3' METHYLMETAQUALONE; ANTILIPEMIC AGENT; APOLIPOPROTEIN B; APOLIPOPROTEIN B100; APOLIPOPROTEIN B48; BILE ACID SEQUESTRANT; BMS 197636; BMS 200150; CARRIER PROTEIN; CHOLESTEROL ESTER; CHYLOMICRON; CP 10447; CP 346086; EZETIMIBE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMPLITAPIDE; JTT 130; LOMITAPIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MITOCHONDRIAL TRIGLYCERIDE TRANSFER PROTEIN; MITOCHONDRIAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR; NARINGENIN; NARINGENIN 7 O CETYL ETHER; PHOSPHOLIPID; SLX 4090; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERY LOW DENSITY LIPOPROTEIN; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84878646607     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319170023     Document Type: Article
Times cited : (14)

References (141)
  • 3
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005; 352: 1425-35.
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • LaRosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 4
    • 11144355354 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndromes
    • Cannon CP, Braunwald E, McCabe CH, et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 2004; 350: 1495-504.
    • (2004) N Engl J Med , vol.350 , pp. 1495-1504
    • Cannon, C.P.1    Braunwald, E.2    McCabe, C.H.3
  • 5
    • 77049105368 scopus 로고    scopus 로고
    • Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: A large cross-sectional study in The Netherlands
    • Pijlman AH, Huijgen R, Verhagen SN, et al. Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in The Netherlands. Atherosclerosis 2010; 209: 189-94.
    • (2010) Atherosclerosis , vol.209 , pp. 189-194
    • Pijlman, A.H.1    Huijgen, R.2    Verhagen, S.N.3
  • 7
    • 84866684691 scopus 로고    scopus 로고
    • Targeting cardiovascular risk: The impact of age, gender and compliance to treatment
    • Kostapanos MS, Elisaf MS, Mikhailidis DP. Targeting cardiovascular risk: the impact of age, gender and compliance to treatment. Curr Med Res Opin 2012; 28: 1415-9.
    • (2012) Curr Med Res Opin , vol.28 , pp. 1415-1419
    • Kostapanos, M.S.1    Elisaf, M.S.2    Mikhailidis, D.P.3
  • 8
    • 57049123338 scopus 로고    scopus 로고
    • Compliance with lipid-lowering therapy and its impact on cardiovascular morbidity and mortality
    • Liberopoulos EN, Florentin M, Mikhailidis DP, Elisaf MS. Compliance with lipid-lowering therapy and its impact on cardiovascular morbidity and mortality. Expert Opin Drug Saf 2008; 7: 717-25.
    • (2008) Expert Opin Drug Saf , vol.7 , pp. 717-725
    • Liberopoulos, E.N.1    Florentin, M.2    Mikhailidis, D.P.3    Elisaf, M.S.4
  • 9
    • 50849088669 scopus 로고    scopus 로고
    • Discontinuation of statin therapy following an acute myocardial infarction: A population-based study
    • Daskalopoulou SS, Delaney JA, Filion KB, et al. Discontinuation of statin therapy following an acute myocardial infarction: a population-based study. Eur Heart J 2008; 29: 2083-91.
    • (2008) Eur Heart J , vol.29 , pp. 2083-2091
    • Daskalopoulou, S.S.1    Delaney, J.A.2    Filion, K.B.3
  • 12
    • 64749115172 scopus 로고    scopus 로고
    • Lipid-lowering drugs acting at the level of the gastrointestinal tract
    • Filippatos TD, Mikhailidis DP. Lipid-lowering drugs acting at the level of the gastrointestinal tract. Curr Pharm Des 2009; 15: 490-516.
    • (2009) Curr Pharm Des , vol.15 , pp. 490-516
    • Filippatos, T.D.1    Mikhailidis, D.P.2
  • 13
    • 34249005579 scopus 로고    scopus 로고
    • Effect of ezetimibe monotherapy on the concentration of lipoprotein subfractions in patients with primary dyslipidaemia
    • Kalogirou M, Tsimihodimos V, Gazi I, et al. Effect of ezetimibe monotherapy on the concentration of lipoprotein subfractions in patients with primary dyslipidaemia. Curr Med Res Opin 2007; 23: 1169-76.
    • (2007) Curr Med Res Opin , vol.23 , pp. 1169-1176
    • Kalogirou, M.1    Tsimihodimos, V.2    Gazi, I.3
  • 14
    • 42549095738 scopus 로고    scopus 로고
    • Colesevelam hydrochloride in clinical practice: A new approach in the treatment of hypercholesterolaemia
    • Florentin M, Liberopoulos EN, Mikhailidis DP, Elisaf MS. Colesevelam hydrochloride in clinical practice: a new approach in the treatment of hypercholesterolaemia. Curr Med Res Opin 2008; 24: 995-1009.
    • (2008) Curr Med Res Opin , vol.24 , pp. 995-1009
    • Florentin, M.1    Liberopoulos, E.N.2    Mikhailidis, D.P.3    Elisaf, M.S.4
  • 15
    • 80052492899 scopus 로고    scopus 로고
    • Achievement of treatment goals for primary prevention of cardiovascular disease in clinical practice across Europe: The EURIKA study
    • Banegas JR, Lopez-Garcia E, Dallongeville J, et al. Achievement of treatment goals for primary prevention of cardiovascular disease in clinical practice across Europe: the EURIKA study. Eur Heart J 2011; 32: 2143-52.
    • (2011) Eur Heart J , vol.32 , pp. 2143-2152
    • Banegas, J.R.1    Lopez-Garcia, E.2    Dallongeville, J.3
  • 16
    • 0032554676 scopus 로고    scopus 로고
    • Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS)
    • Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation 1998; 97: 1440-5.
    • (1998) Circulation , vol.97 , pp. 1440-1445
  • 17
    • 84857127381 scopus 로고    scopus 로고
    • Editorial: Reducing cardiovascular risk: Is low-density lipoprotein-cholesterol (LDL-C) lowering enough?
    • Kostapanos MS, Katsiki N, Elisaf MS, Mikhailidis DP. Editorial: reducing cardiovascular risk: is low-density lipoprotein-cholesterol (LDL-C) lowering enough? Curr Vasc Pharmacol 2012; 10: 173-7.
    • (2012) Curr Vasc Pharmacol , vol.10 , pp. 173-177
    • Kostapanos, M.S.1    Katsiki, N.2    Elisaf, M.S.3    Mikhailidis, D.P.4
  • 18
    • 79958148945 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management
    • Chapman MJ, Ginsberg HN, Amarenco P, et al. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J 2011; 32: 1345-61.
    • (2011) Eur Heart J , vol.32 , pp. 1345-1361
    • Chapman, M.J.1    Ginsberg, H.N.2    Amarenco, P.3
  • 19
    • 0023677501 scopus 로고
    • Reduced atherogenesis in cholesterol-fed diabetic rabbits. Giant lipoproteins do not enter the arterial wall
    • Nordestgaard BG, Stender S, Kjeldsen K. Reduced atherogenesis in cholesterol-fed diabetic rabbits. Giant lipoproteins do not enter the arterial wall. Arteriosclerosis 1988; 8: 421-8.
    • (1988) Arteriosclerosis , vol.8 , pp. 421-428
    • Nordestgaard, B.G.1    Stender, S.2    Kjeldsen, K.3
  • 20
    • 0028172762 scopus 로고
    • Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
    • Rapp JH, Lespine A, Hamilton RL, et al. Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler Thromb 1994; 14: 1767-74.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1767-1774
    • Rapp, J.H.1    Lespine, A.2    Hamilton, R.L.3
  • 21
    • 80051769525 scopus 로고    scopus 로고
    • "European panel on low density lipoprotein (LDL) subclasses": A statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses: Executive summary
    • Mikhailidis DP, Elisaf M, Rizzo M, et al. "European panel on low density lipoprotein (LDL) subclasses": a statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses: executive summary. Curr Vasc Pharmacol 2011; 9: 531-2.
    • (2011) Curr Vasc Pharmacol , vol.9 , pp. 531-532
    • Mikhailidis, D.P.1    Elisaf, M.2    Rizzo, M.3
  • 22
    • 80051725784 scopus 로고    scopus 로고
    • "European panel on low density lipoprotein (LDL) subclasses": A statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses
    • Mikhailidis DP, Elisaf M, Rizzo M, et al. "European panel on low density lipoprotein (LDL) subclasses": a statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses. Curr Vasc Pharmacol 2011; 9: 533-71.
    • (2011) Curr Vasc Pharmacol , vol.9 , pp. 533-571
    • Mikhailidis, D.P.1    Elisaf, M.2    Rizzo, M.3
  • 23
    • 34548166870 scopus 로고    scopus 로고
    • Remnant-like lipoprotein particles impair endothelial function: Direct and indirect effects on nitric oxide synthase
    • Zheng XY, Liu L. Remnant-like lipoprotein particles impair endothelial function: direct and indirect effects on nitric oxide synthase. J Lipid Res 2007; 48: 1673-80.
    • (2007) J Lipid Res , vol.48 , pp. 1673-1680
    • Zheng, X.Y.1    Liu, L.2
  • 24
    • 13244257207 scopus 로고    scopus 로고
    • Acute effect of high-fat meal on endothelial function in moderately dyslipidemic subjects
    • Giannattasio C, Zoppo A, Gentile G, et al. Acute effect of high-fat meal on endothelial function in moderately dyslipidemic subjects. Arterioscler Thromb Vasc Biol 2005; 25: 406-10.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 406-410
    • Giannattasio, C.1    Zoppo, A.2    Gentile, G.3
  • 25
    • 84864809883 scopus 로고    scopus 로고
    • Smaller Mean LDL Particle Size and Higher Proportion of Small Dense LDL in Korean Type 2 Diabetic Patients
    • Suh S, Park HD, Kim SW, et al. Smaller Mean LDL Particle Size and Higher Proportion of Small Dense LDL in Korean Type 2 Diabetic Patients. Diabetes Metab J 2011; 35: 536-42.
    • (2011) Diabetes Metab J , vol.35 , pp. 536-542
    • Suh, S.1    Park, H.D.2    Kim, S.W.3
  • 26
    • 33745140143 scopus 로고    scopus 로고
    • Concentration and relative distribution of low-density lipoprotein subfractions in patients with metabolic syndrome defined according to the National Cholesterol Education Program criteria
    • Gazi I, Tsimihodimos V, Filippatos T, et al. Concentration and relative distribution of low-density lipoprotein subfractions in patients with metabolic syndrome defined according to the National Cholesterol Education Program criteria. Metabolism 2006; 55: 885-91.
    • (2006) Metabolism , vol.55 , pp. 885-891
    • Gazi, I.1    Tsimihodimos, V.2    Filippatos, T.3
  • 27
    • 33749641640 scopus 로고    scopus 로고
    • The hypertriglyceridemic waist phenotype is a predictor of elevated levels of small, dense LDL cholesterol
    • Gazi IF, Filippatos TD, Tsimihodimos V, et al. The hypertriglyceridemic waist phenotype is a predictor of elevated levels of small, dense LDL cholesterol. Lipids 2006; 41: 647-54.
    • (2006) Lipids , vol.41 , pp. 647-654
    • Gazi, I.F.1    Filippatos, T.D.2    Tsimihodimos, V.3
  • 29
    • 64649106575 scopus 로고    scopus 로고
    • Small and dense LDL in familial combined hyperlipidemia and N291S polymorphism of the lipoprotein lipase gene
    • Lopez-Ruiz A, Jarabo MM, Martinez-Triguero ML, et al. Small and dense LDL in familial combined hyperlipidemia and N291S polymorphism of the lipoprotein lipase gene. Lipids Health Dis 2009; 8: 12.
    • (2009) Lipids Health Dis , vol.8 , pp. 12
    • Lopez-Ruiz, A.1    Jarabo, M.M.2    Martinez-Triguero, M.L.3
  • 30
    • 0038645309 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial)
    • Jones PH, Davidson MH, Stein EA, et al. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial). Am J Cardiol 2003; 92: 152-60.
    • (2003) Am J Cardiol , vol.92 , pp. 152-160
    • Jones, P.H.1    Davidson, M.H.2    Stein, E.A.3
  • 31
    • 61449167084 scopus 로고    scopus 로고
    • Dose-dependent effect of rosuvastatin treatment on HDL-subfraction phenotype in patients with primary hyperlipidemia
    • Kostapanos MS, Milionis HJ, Filippatos TD, et al. Dose-dependent effect of rosuvastatin treatment on HDL-subfraction phenotype in patients with primary hyperlipidemia. J Cardiovasc Pharmacol Ther 2009; 14: 5-13.
    • (2009) J Cardiovasc Pharmacol Ther , vol.14 , pp. 5-13
    • Kostapanos, M.S.1    Milionis, H.J.2    Filippatos, T.D.3
  • 32
    • 0036802354 scopus 로고    scopus 로고
    • Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients
    • Asztalos BF, Horvath KV, McNamara JR, et al. Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients. Atherosclerosis 2002; 164: 361-9.
    • (2002) Atherosclerosis , vol.164 , pp. 361-369
    • Asztalos, B.F.1    Horvath, K.V.2    McNamara, J.R.3
  • 33
    • 34548297933 scopus 로고    scopus 로고
    • A 12-week, prospective, open-label analysis of the effect of rosuvastatin on triglyceride-rich lipoprotein metabolism in patients with primary dyslipidemia
    • Kostapanos MS, Milionis HJ, Filippatos TD, et al. A 12-week, prospective, open-label analysis of the effect of rosuvastatin on triglyceride-rich lipoprotein metabolism in patients with primary dyslipidemia. Clin Ther 2007; 29: 1403-14.
    • (2007) Clin Ther , vol.29 , pp. 1403-1414
    • Kostapanos, M.S.1    Milionis, H.J.2    Filippatos, T.D.3
  • 34
    • 48049109174 scopus 로고    scopus 로고
    • Baseline triglyceride levels and insulin sensitivity are major determinants of the increase of LDL particle size and buoyancy induced by rosuvastatin treatment in patients with primary hyperlipidemia
    • Kostapanos MS, Milionis HJ, Lagos KG, et al. Baseline triglyceride levels and insulin sensitivity are major determinants of the increase of LDL particle size and buoyancy induced by rosuvastatin treatment in patients with primary hyperlipidemia. Eur J Pharmacol 2008; 590: 327-32.
    • (2008) Eur J Pharmacol , vol.590 , pp. 327-332
    • Kostapanos, M.S.1    Milionis, H.J.2    Lagos, K.G.3
  • 35
    • 84857039646 scopus 로고    scopus 로고
    • Efficacy of colesevelam on lowering glycemia and lipids
    • Aggarwal S, Loomba RS, Arora RR. Efficacy of colesevelam on lowering glycemia and lipids. J Cardiovasc Pharmacol 2012; 59: 198-205.
    • (2012) J Cardiovasc Pharmacol , vol.59 , pp. 198-205
    • Aggarwal, S.1    Loomba, R.S.2    Arora, R.R.3
  • 36
    • 84868563102 scopus 로고    scopus 로고
    • Effect of Atorvastatin Monotherapy and Low-Dose Atorvastatin/Ezetimibe Combination on Fasting and Postprandial Triglycerides in Combined Hyperlipidemia
    • Kostapanos MS, Elisaf MS, Mikhailidis DP. Effect of Atorvastatin Monotherapy and Low-Dose Atorvastatin/Ezetimibe Combination on Fasting and Postprandial Triglycerides in Combined Hyperlipidemia. J Cardiovasc Pharmacol Ther 2012; 17: 427.
    • (2012) J Cardiovasc Pharmacol Ther , vol.17 , pp. 427
    • Kostapanos, M.S.1    Elisaf, M.S.2    Mikhailidis, D.P.3
  • 37
    • 84862865263 scopus 로고    scopus 로고
    • Nicotinic acid: Clinical considerations
    • Kei A, Elisaf MS. Nicotinic acid: clinical considerations. Expert Opin Drug Saf 2012; 11: 551-64.
    • (2012) Expert Opin Drug Saf , vol.11 , pp. 551-564
    • Kei, A.1    Elisaf, M.S.2
  • 38
    • 34447314752 scopus 로고    scopus 로고
    • The effect of orlistat and fenofibrate, alone or in combination, on small dense LDL and lipoprotein-associated phospholipase A2 in obese patients with metabolic syndrome
    • Filippatos TD, Gazi IF, Liberopoulos EN, et al. The effect of orlistat and fenofibrate, alone or in combination, on small dense LDL and lipoprotein-associated phospholipase A2 in obese patients with metabolic syndrome. Atherosclerosis 2007; 193: 428-37.
    • (2007) Atherosclerosis , vol.193 , pp. 428-437
    • Filippatos, T.D.1    Gazi, I.F.2    Liberopoulos, E.N.3
  • 39
    • 84865235974 scopus 로고    scopus 로고
    • Effect of rosuvastatin monotherapy or in combination with fenofibrate or omega-3 fatty acids on lipoprotein subfraction profile in patients with mixed dyslipidaemia and metabolic syndrome
    • Agouridis AP, Kostapanos MS, Tsimihodimos V, et al. Effect of rosuvastatin monotherapy or in combination with fenofibrate or omega-3 fatty acids on lipoprotein subfraction profile in patients with mixed dyslipidaemia and metabolic syndrome. Int J Clin Pract 2012; 66: 843-53.
    • (2012) Int J Clin Pract , vol.66 , pp. 843-853
    • Agouridis, A.P.1    Kostapanos, M.S.2    Tsimihodimos, V.3
  • 40
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
    • Keech A, Simes RJ, Barter P, et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 2005; 366: 1849-61.
    • (2005) Lancet , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3
  • 41
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • Boden WE, Probstfield JL, Anderson T, et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med 2011; 365: 2255-67.
    • (2011) N Engl J Med , vol.365 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3
  • 42
    • 84866070612 scopus 로고    scopus 로고
    • Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis
    • Rizos EC, Ntzani EE, Bika E, et al. Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis. JAMA 2012; 308: 1024-33.
    • (2012) JAMA , vol.308 , pp. 1024-1033
    • Rizos, E.C.1    Ntzani, E.E.2    Bika, E.3
  • 45
    • 33645767253 scopus 로고    scopus 로고
    • Inhibition of the synthesis of apolipoprotein B-containing lipoproteins
    • Greeve J. Inhibition of the synthesis of apolipoprotein B-containing lipoproteins. Handb Exp Pharmacol 2005: 483-517.
    • (2005) Handb Exp Pharmacol , pp. 483-517
    • Greeve, J.1
  • 46
    • 0032865070 scopus 로고    scopus 로고
    • Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver
    • Davis RA. Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver. Biochim Biophys Acta 1999; 1440: 1-31.
    • (1999) Biochim Biophys Acta , vol.1440 , pp. 1-31
    • Davis, R.A.1
  • 47
    • 0027937873 scopus 로고
    • apoB-100 has a pentapartite structure composed of three amphipathic alpha-helical domains alternating with two amphipathic beta-strand domains. Detection by the computer program LOCATE
    • Segrest JP, Jones MK, Mishra VK, et al. apoB-100 has a pentapartite structure composed of three amphipathic alpha-helical domains alternating with two amphipathic beta-strand domains. Detection by the computer program LOCATE. Arterioscler Thromb 1994; 14: 1674-85.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1674-1685
    • Segrest, J.P.1    Jones, M.K.2    Mishra, V.K.3
  • 48
    • 0026780342 scopus 로고
    • Lipoprotein assembly. Apolipoprotein B size determines lipoprotein core circumference
    • Spring DJ, Chen-Liu LW, Chatterton JE, et al. Lipoprotein assembly. Apolipoprotein B size determines lipoprotein core circumference. J Biol Chem 1992; 267: 14839-45.
    • (1992) J Biol Chem , vol.267 , pp. 14839-14845
    • Spring, D.J.1    Chen-Liu, L.W.2    Chatterton, J.E.3
  • 49
    • 0034717836 scopus 로고    scopus 로고
    • Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly
    • Gordon DA, Jamil H. Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly. Biochim Biophys Acta 2000; 1486: 72-83.
    • (2000) Biochim Biophys Acta , vol.1486 , pp. 72-83
    • Gordon, D.A.1    Jamil, H.2
  • 50
    • 0036740573 scopus 로고    scopus 로고
    • Inhibition of hepatocyte apoB secretion by naringenin: Enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters
    • Borradaile NM, de Dreu LE, Barrett PH, Huff MW. Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters. J Lipid Res 2002; 43: 1544-54.
    • (2002) J Lipid Res , vol.43 , pp. 1544-1554
    • Borradaile, N.M.1    de Dreu, L.E.2    Barrett, P.H.3    Huff, M.W.4
  • 51
    • 0032861798 scopus 로고    scopus 로고
    • The assembly and secretion of apolipoprotein B-containing lipoproteins
    • Olofsson SO, Asp L, Boren J. The assembly and secretion of apolipoprotein B-containing lipoproteins. Curr Opin Lipidol 1999; 10: 341-6.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 341-346
    • Olofsson, S.O.1    Asp, L.2    Boren, J.3
  • 52
    • 0030062964 scopus 로고    scopus 로고
    • Mechanism of native oat phytochrome photoreversion: A time-resolved absorption investigation
    • Chen E, Lapko VN, Lewis JW, et al. Mechanism of native oat phytochrome photoreversion: a time-resolved absorption investigation. Biochemistry 1996; 35: 843-50.
    • (1996) Biochemistry , vol.35 , pp. 843-850
    • Chen, E.1    Lapko, V.N.2    Lewis, J.W.3
  • 53
    • 0035958917 scopus 로고    scopus 로고
    • The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways
    • Fisher EA, Pan M, Chen X, et al. The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways. J Biol Chem 2001; 276: 27855-63.
    • (2001) J Biol Chem , vol.276 , pp. 27855-27863
    • Fisher, E.A.1    Pan, M.2    Chen, X.3
  • 54
    • 0027094799 scopus 로고
    • Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins
    • Chan L. Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins. J Biol Chem 1992; 267: 25621-4.
    • (1992) J Biol Chem , vol.267 , pp. 25621-25624
    • Chan, L.1
  • 55
    • 0029975626 scopus 로고    scopus 로고
    • The microsomal triglyceride transfer protein facilitates assembly and secretion of apolipoprotein B-containing lipoproteins and decreases cotranslational degradation of apolipoprotein B in transfected COS-7 cells
    • Wang S, McLeod RS, Gordon DA, Yao Z. The microsomal triglyceride transfer protein facilitates assembly and secretion of apolipoprotein B-containing lipoproteins and decreases cotranslational degradation of apolipoprotein B in transfected COS-7 cells. J Biol Chem 1996; 271: 14124-33.
    • (1996) J Biol Chem , vol.271 , pp. 14124-14133
    • Wang, S.1    McLeod, R.S.2    Gordon, D.A.3    Yao, Z.4
  • 56
    • 84857133310 scopus 로고    scopus 로고
    • Multiple functions of microsomal triglyceride transfer protein
    • Hussain MM, Rava P, Walsh M, et al. Multiple functions of microsomal triglyceride transfer protein. Nutr Metab (Lond) 2012; 9: 14.
    • (2012) Nutr Metab (Lond) , vol.9 , pp. 14
    • Hussain, M.M.1    Rava, P.2    Walsh, M.3
  • 57
    • 0037244002 scopus 로고    scopus 로고
    • Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly
    • Hussain MM, Shi J, Dreizen P. Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly. J Lipid Res 2003; 44: 22-32.
    • (2003) J Lipid Res , vol.44 , pp. 22-32
    • Hussain, M.M.1    Shi, J.2    Dreizen, P.3
  • 58
    • 0242304509 scopus 로고    scopus 로고
    • Microsomal triglyceride transfer protein: A multifunctional protein
    • Hussain MM, Iqbal J, Anwar K, et al. Microsomal triglyceride transfer protein: a multifunctional protein. Front Biosci 2003; 8: s500-6.
    • (2003) Front Biosci , vol.8
    • Hussain, M.M.1    Iqbal, J.2    Anwar, K.3
  • 59
    • 0033827087 scopus 로고    scopus 로고
    • APOLIPOPROTEIN B: MRNA editing, lipoprotein assembly, and presecretory degradation
    • Davidson NO, Shelness GS. APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation. Annu Rev Nutr 2000; 20: 169-93.
    • (2000) Annu Rev Nutr , vol.20 , pp. 169-193
    • Davidson, N.O.1    Shelness, G.S.2
  • 60
    • 0035655157 scopus 로고    scopus 로고
    • Structure of apolipoprotein B-100 in low density lipoproteins
    • Segrest JP, Jones MK, De Loof H, Dashti N. Structure of apolipoprotein B-100 in low density lipoproteins. J Lipid Res 2001; 42: 1346-67.
    • (2001) J Lipid Res , vol.42 , pp. 1346-1367
    • Segrest, J.P.1    Jones, M.K.2    de Loof, H.3    Dashti, N.4
  • 61
    • 0022857828 scopus 로고
    • Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia
    • Lackner KJ, Monge JC, Gregg RE, et al. Analysis of the apolipoprotein B gene and messenger ribonucleic acid in abetalipoproteinemia. J Clin Invest 1986; 78: 1707-12.
    • (1986) J Clin Invest , vol.78 , pp. 1707-1712
    • Lackner, K.J.1    Monge, J.C.2    Gregg, R.E.3
  • 62
    • 4644258786 scopus 로고    scopus 로고
    • Identification of microsomal triglyceride transfer protein in intestinal brush-border membrane
    • Slight I, Bendayan M, Malo C, et al. Identification of microsomal triglyceride transfer protein in intestinal brush-border membrane. Exp Cell Res 2004; 300: 11-22.
    • (2004) Exp Cell Res , vol.300 , pp. 11-22
    • Slight, I.1    Bendayan, M.2    Malo, C.3
  • 63
    • 0025329901 scopus 로고
    • Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex
    • Wetterau JR, Combs KA, Spinner SN, Joiner BJ. Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex. J Biol Chem 1990; 265: 9800-7.
    • (1990) J Biol Chem , vol.265 , pp. 9800-9807
    • Wetterau, J.R.1    Combs, K.A.2    Spinner, S.N.3    Joiner, B.J.4
  • 64
    • 0030783252 scopus 로고    scopus 로고
    • The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion
    • Wang L, Fast DG, Attie AD. The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion. J Biol Chem 1997; 272: 27644-51.
    • (1997) J Biol Chem , vol.272 , pp. 27644-27651
    • Wang, L.1    Fast, D.G.2    Attie, A.D.3
  • 65
    • 0026052386 scopus 로고
    • Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein
    • Wetterau JR, Combs KA, McLean LR, et al. Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein. Biochemistry 1991; 30: 9728-35.
    • (1991) Biochemistry , vol.30 , pp. 9728-9735
    • Wetterau, J.R.1    Combs, K.A.2    McLean, L.R.3
  • 67
    • 23244441822 scopus 로고    scopus 로고
    • Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein
    • Rava P, Athar H, Johnson C, Hussain MM. Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein. J Lipid Res 2005; 46: 1779-85.
    • (2005) J Lipid Res , vol.46 , pp. 1779-1785
    • Rava, P.1    Athar, H.2    Johnson, C.3    Hussain, M.M.4
  • 68
    • 0033600905 scopus 로고    scopus 로고
    • The activity of microsomal triglyceride transfer protein is essential for accumulation of triglyceride within microsomes in McA-RH7777 cells. A unified model for the assembly of very low density lipoproteins
    • Wang Y, Tran K, Yao Z. The activity of microsomal triglyceride transfer protein is essential for accumulation of triglyceride within microsomes in McA-RH7777 cells. A unified model for the assembly of very low density lipoproteins. J Biol Chem 1999; 274: 27793-800.
    • (1999) J Biol Chem , vol.274 , pp. 27793-27800
    • Wang, Y.1    Tran, K.2    Yao, Z.3
  • 69
    • 0032570590 scopus 로고    scopus 로고
    • The microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cells
    • Rustaeus S, Stillemark P, Lindberg K, et al. The microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cells. J Biol Chem 1998; 273: 5196-203.
    • (1998) J Biol Chem , vol.273 , pp. 5196-5203
    • Rustaeus, S.1    Stillemark, P.2    Lindberg, K.3
  • 70
    • 12644303527 scopus 로고    scopus 로고
    • Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step
    • Gordon DA, Jamil H, Gregg RE, et al. Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step. J Biol Chem 1996; 271: 33047-53.
    • (1996) J Biol Chem , vol.271 , pp. 33047-33053
    • Gordon, D.A.1    Jamil, H.2    Gregg, R.E.3
  • 71
    • 0027486706 scopus 로고
    • Mechanism of microsomal triglyceride transfer protein catalyzed lipid transport
    • Atzel A, Wetterau JR. Mechanism of microsomal triglyceride transfer protein catalyzed lipid transport. Biochemistry 1993; 32: 10444-50.
    • (1993) Biochemistry , vol.32 , pp. 10444-10450
    • Atzel, A.1    Wetterau, J.R.2
  • 72
    • 0028606834 scopus 로고
    • Identification of two classes of lipid molecule binding sites on the microsomal triglyceride transfer protein
    • Atzel A, Wetterau JR. Identification of two classes of lipid molecule binding sites on the microsomal triglyceride transfer protein. Biochemistry 1994; 33: 15382-8.
    • (1994) Biochemistry , vol.33 , pp. 15382-15388
    • Atzel, A.1    Wetterau, J.R.2
  • 73
    • 0028953341 scopus 로고
    • Microsomal triglyceride transfer protein. Specificity of lipid binding and transport
    • Jamil H, Dickson JK, Jr., Chu CH, et al. Microsomal triglyceride transfer protein. Specificity of lipid binding and transport. J Biol Chem 1995; 270: 6549-54.
    • (1995) J Biol Chem , vol.270 , pp. 6549-6554
    • Jamil, H.1    Dickson Jr., J.K.2    Chu, C.H.3
  • 74
    • 0030660157 scopus 로고    scopus 로고
    • Apolipoprotein B binding to microsomal triglyceride transfer protein decreases with increases in length and lipidation: Implications in lipoprotein biosynthesis
    • Hussain MM, Bakillah A, Jamil H. Apolipoprotein B binding to microsomal triglyceride transfer protein decreases with increases in length and lipidation: implications in lipoprotein biosynthesis. Biochemistry 1997; 36: 13060-7.
    • (1997) Biochemistry , vol.36 , pp. 13060-13067
    • Hussain, M.M.1    Bakillah, A.2    Jamil, H.3
  • 75
    • 0034712665 scopus 로고    scopus 로고
    • Decreased secretion of ApoB follows inhibition of ApoB-MTP binding by a novel antagonist
    • Bakillah A, Nayak N, Saxena U, et al. Decreased secretion of ApoB follows inhibition of ApoB-MTP binding by a novel antagonist. Biochemistry 2000; 39: 4892-9.
    • (2000) Biochemistry , vol.39 , pp. 4892-4899
    • Bakillah, A.1    Nayak, N.2    Saxena, U.3
  • 76
    • 0027966127 scopus 로고
    • Secretion of apolipoprotein Bcontaining lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability
    • Gordon DA, Jamil H, Sharp D, et al. Secretion of apolipoprotein Bcontaining lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability. Proc Natl Acad Sci U S A 1994; 91: 7628-32.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7628-7632
    • Gordon, D.A.1    Jamil, H.2    Sharp, D.3
  • 77
    • 0028128428 scopus 로고
    • Microsomal triglyceride transfer protein, the abetalipoproteinemia gene product, mediates the secretion of apolipoprotein B-containing lipoproteins from heterologous cells
    • Leiper JM, Bayliss JD, Pease RJ, et al. Microsomal triglyceride transfer protein, the abetalipoproteinemia gene product, mediates the secretion of apolipoprotein B-containing lipoproteins from heterologous cells. J Biol Chem 1994; 269: 21951-4.
    • (1994) J Biol Chem , vol.269 , pp. 21951-21954
    • Leiper, J.M.1    Bayliss, J.D.2    Pease, R.J.3
  • 78
    • 0028890198 scopus 로고
    • Murine mammaryderived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core
    • Herscovitz H, Kritis A, Talianidis I, et al. Murine mammaryderived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core. Proc Natl Acad Sci U S A 1995; 92: 659-63.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 659-663
    • Herscovitz, H.1    Kritis, A.2    Talianidis, I.3
  • 79
    • 0030909990 scopus 로고    scopus 로고
    • In vitro reconstitution of assembly of apolipoprotein B48-containing lipoproteins
    • Rusinol AE, Jamil H, Vance JE. In vitro reconstitution of assembly of apolipoprotein B48-containing lipoproteins. J Biol Chem 1997; 272: 8019-25.
    • (1997) J Biol Chem , vol.272 , pp. 8019-8025
    • Rusinol, A.E.1    Jamil, H.2    Vance, J.E.3
  • 80
    • 0034610084 scopus 로고    scopus 로고
    • Translocational status of ApoB in the presence of an inhibitor of microsomal triglyceride transfer protein
    • Macri J, Kazemian P, Kulinski A, et al. Translocational status of ApoB in the presence of an inhibitor of microsomal triglyceride transfer protein. Biochem Biophys Res Commun 2000; 276: 1035-47.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 1035-1047
    • Macri, J.1    Kazemian, P.2    Kulinski, A.3
  • 81
    • 0029047046 scopus 로고
    • Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: Insulin negatively regulates MTP gene expression
    • Lin MC, Gordon D, Wetterau JR. Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression. J Lipid Res 1995; 36: 1073-81.
    • (1995) J Lipid Res , vol.36 , pp. 1073-1081
    • Lin, M.C.1    Gordon, D.2    Wetterau, J.R.3
  • 82
    • 0242516072 scopus 로고    scopus 로고
    • Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: Roles of MAPKerk and MAPKp38
    • Au WS, Kung HF, Lin MC. Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: roles of MAPKerk and MAPKp38. Diabetes 2003; 52: 1073-80.
    • (2003) Diabetes , vol.52 , pp. 1073-1080
    • Au, W.S.1    Kung, H.F.2    Lin, M.C.3
  • 83
    • 39049142758 scopus 로고    scopus 로고
    • Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells
    • Jin UH, Kang YJ, Chang YC, Kim CH. Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells. J Cell Biochem 2008; 103: 908-19.
    • (2008) J Cell Biochem , vol.103 , pp. 908-919
    • Jin, U.H.1    Kang, Y.J.2    Chang, Y.C.3    Kim, C.H.4
  • 84
    • 33646412333 scopus 로고    scopus 로고
    • Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: The role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein
    • Lally S, Tan CY, Owens D, Tomkin GH. Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: the role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein. Diabetologia 2006; 49: 1008-16.
    • (2006) Diabetologia , vol.49 , pp. 1008-1016
    • Lally, S.1    Tan, C.Y.2    Owens, D.3    Tomkin, G.H.4
  • 85
    • 33847012545 scopus 로고    scopus 로고
    • Tumor necrosis factoralpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins
    • Qin B, Qiu W, Avramoglu RK, Adeli K. Tumor necrosis factoralpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins. Diabetes 2007; 56: 450-61.
    • (2007) Diabetes , vol.56 , pp. 450-461
    • Qin, B.1    Qiu, W.2    Avramoglu, R.K.3    Adeli, K.4
  • 86
    • 45849111008 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling
    • Qin B, Anderson RA, Adeli K. Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling. Am J Physiol Gastrointest Liver Physiol 2008; 294: G1120-9.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Qin, B.1    Anderson, R.A.2    Adeli, K.3
  • 87
    • 0030800343 scopus 로고    scopus 로고
    • Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein
    • Benoist F, Grand-Perret T. Co-translational degradation of apolipoprotein B100 by the proteasome is prevented by microsomal triglyceride transfer protein. Synchronized translation studies on HepG2 cells treated with an inhibitor of microsomal triglyceride transfer protein. J Biol Chem 1997; 272: 20435-42.
    • (1997) J Biol Chem , vol.272 , pp. 20435-20442
    • Benoist, F.1    Grand-Perret, T.2
  • 88
    • 26844580001 scopus 로고    scopus 로고
    • JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs
    • Aggarwal D, West KL, Zern TL, et al. JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs. BMC Cardiovasc Disord 2005; 5: 30.
    • (2005) BMC Cardiovasc Disord , vol.5 , pp. 30
    • Aggarwal, D.1    West, K.L.2    Zern, T.L.3
  • 90
    • 20044368479 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes
    • Allister EM, Borradaile NM, Edwards JY, Huff MW. Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes. Diabetes 2005; 54: 1676-83.
    • (2005) Diabetes , vol.54 , pp. 1676-1683
    • Allister, E.M.1    Borradaile, N.M.2    Edwards, J.Y.3    Huff, M.W.4
  • 91
    • 0037432066 scopus 로고    scopus 로고
    • Hepatocyte apoBcontaining lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation
    • Borradaile NM, de Dreu LE, Barrett PH, et al. Hepatocyte apoBcontaining lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation. Biochemistry 2003; 42: 1283-91.
    • (2003) Biochemistry , vol.42 , pp. 1283-1291
    • Borradaile, N.M.1    de Dreu, L.E.2    Barrett, P.H.3
  • 92
    • 0034989204 scopus 로고    scopus 로고
    • Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP
    • Wilcox LJ, Borradaile NM, de Dreu LE, Huff MW. Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. J Lipid Res 2001; 42: 725-34.
    • (2001) J Lipid Res , vol.42 , pp. 725-734
    • Wilcox, L.J.1    Borradaile, N.M.2    de Dreu, L.E.3    Huff, M.W.4
  • 93
    • 0033043969 scopus 로고    scopus 로고
    • Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin
    • Borradaile NM, Carroll KK, Kurowska EM. Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin. Lipids 1999; 34: 591-8.
    • (1999) Lipids , vol.34 , pp. 591-598
    • Borradaile, N.M.1    Carroll, K.K.2    Kurowska, E.M.3
  • 94
    • 0033199150 scopus 로고    scopus 로고
    • Hypocholesterolemic effect of naringin associated with hepatic cholesterol regulating enzyme changes in rats
    • Shin YW, Bok SH, Jeong TS, et al. Hypocholesterolemic effect of naringin associated with hepatic cholesterol regulating enzyme changes in rats. Int J Vitam Nutr Res 1999; 69: 341-7.
    • (1999) Int J Vitam Nutr Res , vol.69 , pp. 341-347
    • Shin, Y.W.1    Bok, S.H.2    Jeong, T.S.3
  • 95
    • 0037294718 scopus 로고    scopus 로고
    • Naringenin 7-O-cetyl ether as inhibitor of HMG-CoA reductase and modulator of plasma and hepatic lipids in high cholesterol-fed rats
    • Lee MK, Moon SS, Lee SE, et al. Naringenin 7-O-cetyl ether as inhibitor of HMG-CoA reductase and modulator of plasma and hepatic lipids in high cholesterol-fed rats. Bioorg Med Chem 2003; 11: 393-8.
    • (2003) Bioorg Med Chem , vol.11 , pp. 393-398
    • Lee, M.K.1    Moon, S.S.2    Lee, S.E.3
  • 96
    • 0032725927 scopus 로고    scopus 로고
    • Cholesterol-lowering activity of naringenin via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:Cholesterol acyltransferase in rats
    • Lee SH, Park YB, Bae KH, et al. Cholesterol-lowering activity of naringenin via inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase in rats. Ann Nutr Metab 1999; 43: 173-80.
    • (1999) Ann Nutr Metab , vol.43 , pp. 173-180
    • Lee, S.H.1    Park, Y.B.2    Bae, K.H.3
  • 97
    • 0034813893 scopus 로고    scopus 로고
    • Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits
    • Lee CH, Jeong TS, Choi YK, et al. Anti-atherogenic effect of citrus flavonoids, naringin and naringenin, associated with hepatic ACAT and aortic VCAM-1 and MCP-1 in high cholesterol-fed rabbits. Biochem Biophys Res Commun 2001; 284: 681-8.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 681-688
    • Lee, C.H.1    Jeong, T.S.2    Choi, Y.K.3
  • 98
    • 0033008969 scopus 로고    scopus 로고
    • Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase and acyl CoA: Cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus bioflavonoids
    • Bok SH, Lee SH, Park YB, et al. Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase and acyl CoA: cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus bioflavonoids. J Nutr 1999; 129: 1182-5.
    • (1999) J Nutr , vol.129 , pp. 1182-1185
    • Bok, S.H.1    Lee, S.H.2    Park, Y.B.3
  • 99
    • 0141643289 scopus 로고    scopus 로고
    • Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation
    • Borradaile NM, de Dreu LE, Huff MW. Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation. Diabetes 2003; 52: 2554-61.
    • (2003) Diabetes , vol.52 , pp. 2554-2561
    • Borradaile, N.M.1    de Dreu, L.E.2    Huff, M.W.3
  • 100
    • 0025897408 scopus 로고
    • Improvement of hyperglycemia and hyperlipemia in streptozotocin-diabetic rats by a methanolic extract of Prunus davidiana stems and its main component, prunin
    • Choi JS, Yokozawa T, Oura H. Improvement of hyperglycemia and hyperlipemia in streptozotocin-diabetic rats by a methanolic extract of Prunus davidiana stems and its main component, prunin. Planta Med 1991; 57: 208-11.
    • (1991) Planta Med , vol.57 , pp. 208-211
    • Choi, J.S.1    Yokozawa, T.2    Oura, H.3
  • 101
    • 77950914240 scopus 로고    scopus 로고
    • Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice
    • Mulvihill EE, Assini JM, Sutherland BG, et al. Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice. Arterioscler Thromb Vasc Biol 2010; 30: 742-8.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 742-748
    • Mulvihill, E.E.1    Assini, J.M.2    Sutherland, B.G.3
  • 102
    • 0029741570 scopus 로고    scopus 로고
    • Microsomal triacylglycerol transfer protein prevents presecretory degradation of apolipoprotein B-100. A dithiothreitol-sensitive protease is involved
    • Benoist F, Nicodeme E, Grand-Perret T. Microsomal triacylglycerol transfer protein prevents presecretory degradation of apolipoprotein B-100. A dithiothreitol-sensitive protease is involved. Eur J Biochem 1996; 240: 713-20.
    • (1996) Eur J Biochem , vol.240 , pp. 713-720
    • Benoist, F.1    Nicodeme, E.2    Grand-Perret, T.3
  • 103
    • 0033593209 scopus 로고    scopus 로고
    • Identification of domains in apolipoprotein B100 that confer a high requirement for the microsomal triglyceride transfer protein
    • Nicodeme E, Benoist F, McLeod R, et al. Identification of domains in apolipoprotein B100 that confer a high requirement for the microsomal triglyceride transfer protein. J Biol Chem 1999; 274: 1986-93.
    • (1999) J Biol Chem , vol.274 , pp. 1986-1993
    • Nicodeme, E.1    Benoist, F.2    McLeod, R.3
  • 104
    • 0037199962 scopus 로고    scopus 로고
    • Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation
    • Kulinski A, Rustaeus S, Vance JE. Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation. J Biol Chem 2002; 277: 31516-25.
    • (2002) J Biol Chem , vol.277 , pp. 31516-31525
    • Kulinski, A.1    Rustaeus, S.2    Vance, J.E.3
  • 105
    • 35348994270 scopus 로고    scopus 로고
    • Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells
    • Dashti N, Manchekar M, Liu Y, et al. Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells. J Biol Chem 2007; 282: 28597-608.
    • (2007) J Biol Chem , vol.282 , pp. 28597-28608
    • Dashti, N.1    Manchekar, M.2    Liu, Y.3
  • 106
    • 80052776765 scopus 로고    scopus 로고
    • Lomitapide
    • Lomitapide. Am J Cardiovasc Drugs 2011; 11: 347-52.
    • (2011) Am J Cardiovasc Drugs , vol.11 , pp. 347-352
  • 107
    • 0034971209 scopus 로고    scopus 로고
    • Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells
    • Funatsu T, Suzuki K, Goto M, et al. Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells. Atherosclerosis 2001; 157: 107-15.
    • (2001) Atherosclerosis , vol.157 , pp. 107-115
    • Funatsu, T.1    Suzuki, K.2    Goto, M.3
  • 108
    • 79955372177 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein improves insulin sensitivity and reduces atherogenic risk in Zucker fatty rats
    • Dhote V, Joharapurkar A, Kshirsagar S, et al. Inhibition of microsomal triglyceride transfer protein improves insulin sensitivity and reduces atherogenic risk in Zucker fatty rats. Clin Exp Pharmacol Physiol 2011; 38: 338-44.
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , pp. 338-344
    • Dhote, V.1    Joharapurkar, A.2    Kshirsagar, S.3
  • 109
    • 0037195602 scopus 로고    scopus 로고
    • Atorvastatin increases hepatic fatty acid beta-oxidation in sucrose-fed rats: Comparison with an MTP inhibitor
    • Funatsu T, Kakuta H, Takasu T, Miyata K. Atorvastatin increases hepatic fatty acid beta-oxidation in sucrose-fed rats: comparison with an MTP inhibitor. Eur J Pharmacol 2002; 455: 161-7.
    • (2002) Eur J Pharmacol , vol.455 , pp. 161-167
    • Funatsu, T.1    Kakuta, H.2    Takasu, T.3    Miyata, K.4
  • 110
    • 0035834505 scopus 로고    scopus 로고
    • MTP inhibitor decreases plasma cholesterol levels in LDL receptor-deficient WHHL rabbits by lowering the VLDL secretion
    • Shiomi M, Ito T. MTP inhibitor decreases plasma cholesterol levels in LDL receptor-deficient WHHL rabbits by lowering the VLDL secretion. Eur J Pharmacol 2001; 431: 127-31.
    • (2001) Eur J Pharmacol , vol.431 , pp. 127-131
    • Shiomi, M.1    Ito, T.2
  • 111
    • 0014251571 scopus 로고
    • Associated chest injuries
    • Frankel HL. Associated chest injuries. Paraplegia 1968; 5: 221-5.
    • (1968) Paraplegia , vol.5 , pp. 221-225
    • Frankel, H.L.1
  • 112
    • 79955582390 scopus 로고    scopus 로고
    • Assessment and clinical relevance of non-fasting and postprandial triglycerides: An expert panel statement
    • Kolovou GD, Mikhailidis DP, Kovar J, et al. Assessment and clinical relevance of non-fasting and postprandial triglycerides: an expert panel statement. Curr Vasc Pharmacol 2011; 9: 258-70.
    • (2011) Curr Vasc Pharmacol , vol.9 , pp. 258-270
    • Kolovou, G.D.1    Mikhailidis, D.P.2    Kovar, J.3
  • 113
    • 33745802822 scopus 로고    scopus 로고
    • Drug evaluation: The MTP inhibitor JTT-130 as a potential treatment for hyperlipidemia
    • Burnett JR. Drug evaluation: The MTP inhibitor JTT-130 as a potential treatment for hyperlipidemia. IDrugs 2006; 9: 495-9.
    • (2006) IDrugs , vol.9 , pp. 495-499
    • Burnett, J.R.1
  • 114
    • 78751531122 scopus 로고    scopus 로고
    • Pharmacological characterization of diethyl-2-({3-dimethylcarbamoyl-4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]p henyl}acetyloxymethyl)-2-phenylmalonate (JTT-130), an intestinespecific inhibitor of microsomal triglyceride transfer protein
    • Mera Y, Odani N, Kawai T, et al. Pharmacological characterization of diethyl-2-({3-dimethylcarbamoyl-4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]p henyl}acetyloxymethyl)-2-phenylmalonate (JTT-130), an intestinespecific inhibitor of microsomal triglyceride transfer protein. J Pharmacol Exp Ther 2011; 336: 321-7.
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 321-327
    • Mera, Y.1    Odani, N.2    Kawai, T.3
  • 115
    • 0033213762 scopus 로고    scopus 로고
    • Hypocholesterolemic effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in the guinea pig: Atorvastatin versus simvastatin
    • Conde K, Pineda G, Newton RS, Fernandez ML. Hypocholesterolemic effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in the guinea pig: atorvastatin versus simvastatin. Biochem Pharmacol 1999; 58: 1209-19.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1209-1219
    • Conde, K.1    Pineda, G.2    Newton, R.S.3    Fernandez, M.L.4
  • 116
    • 79951961905 scopus 로고    scopus 로고
    • JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses food intake and gastric emptying with the elevation of plasma peptide YY and glucagon-like peptide-1 in a dietary fat-dependent manner
    • Hata T, Mera Y, Ishii Y, et al. JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses food intake and gastric emptying with the elevation of plasma peptide YY and glucagon-like peptide-1 in a dietary fat-dependent manner. J Pharmacol Exp Ther 2011; 336: 850-6.
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 850-856
    • Hata, T.1    Mera, Y.2    Ishii, Y.3
  • 117
    • 79953046539 scopus 로고    scopus 로고
    • JTT-130, a novel intestinespecific inhibitor of microsomal triglyceride transfer protein, suppresses high fat diet-induced obesity and glucose intolerance in Sprague-Dawley rats
    • Hata T, Mera Y, Tadaki H, et al. JTT-130, a novel intestinespecific inhibitor of microsomal triglyceride transfer protein, suppresses high fat diet-induced obesity and glucose intolerance in Sprague-Dawley rats. Diabetes Obes Metab 2011; 13: 446-54.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 446-454
    • Hata, T.1    Mera, Y.2    Tadaki, H.3
  • 118
    • 31044441037 scopus 로고    scopus 로고
    • New ways in which GLP-1 can regulate glucose homeostasis
    • D'Alessio DA, Sandoval DA, Seeley RJ. New ways in which GLP-1 can regulate glucose homeostasis. J Clin Invest 2005; 115: 3406-8.
    • (2005) J Clin Invest , vol.115 , pp. 3406-3408
    • D'Alessio, D.A.1    Sandoval, D.A.2    Seeley, R.J.3
  • 119
    • 84859247836 scopus 로고    scopus 로고
    • Executive summary: Standards of medical care in diabetes--2012
    • Executive summary: Standards of medical care in diabetes--2012. Diabetes Care 2012; 35 Suppl 1: S4-S10.
    • (2012) Diabetes Care , vol.35 , Issue.SUPPL. 1
  • 120
    • 79956333142 scopus 로고    scopus 로고
    • JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates impaired glucose and lipid metabolism in Zucker diabetic fatty rats
    • Hata T, Mera Y, Kawai T, et al. JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates impaired glucose and lipid metabolism in Zucker diabetic fatty rats. Diabetes Obes Metab 2011; 13: 629-38.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 629-638
    • Hata, T.1    Mera, Y.2    Kawai, T.3
  • 121
    • 79956202758 scopus 로고    scopus 로고
    • A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: Biochemical, pharmacodynamic, pharmacokinetic, and safety profile
    • Kim E, Campbell S, Schueller O, et al. A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther 2011; 337: 775-85.
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 775-785
    • Kim, E.1    Campbell, S.2    Schueller, O.3
  • 122
    • 0029996677 scopus 로고    scopus 로고
    • Inhibition of apolipoprotein B and triglyceride secretion in human hepatoma cells (HepG2)
    • Haghpassand M, Wilder D, Moberly JB. Inhibition of apolipoprotein B and triglyceride secretion in human hepatoma cells (HepG2). J Lipid Res 1996; 37: 1468-80.
    • (1996) J Lipid Res , vol.37 , pp. 1468-1480
    • Haghpassand, M.1    Wilder, D.2    Moberly, J.B.3
  • 123
    • 0034282732 scopus 로고    scopus 로고
    • Inhibition of translocation of nascent apolipoprotein B across the endoplasmic reticulum membrane is associated with selective inhibition of the synthesis of apolipoprotein B
    • Pan M, Liang J, Fisher EA, Ginsberg HN. Inhibition of translocation of nascent apolipoprotein B across the endoplasmic reticulum membrane is associated with selective inhibition of the synthesis of apolipoprotein B. J Biol Chem 2000; 275: 27399-405.
    • (2000) J Biol Chem , vol.275 , pp. 27399-27405
    • Pan, M.1    Liang, J.2    Fisher, E.A.3    Ginsberg, H.N.4
  • 124
    • 16044364083 scopus 로고    scopus 로고
    • An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells
    • Jamil H, Gordon DA, Eustice DC, et al. An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells. Proc Natl Acad Sci U S A 1996; 93: 11991-5.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11991-11995
    • Jamil, H.1    Gordon, D.A.2    Eustice, D.C.3
  • 125
    • 0032837882 scopus 로고    scopus 로고
    • Inactivation of microsomal triglyceride transfer protein impairs the normal redistribution but not the turnover of newly synthesized glycerolipid in the cytosol, endoplasmic reticulum and Golgi of primary rat hepatocytes
    • Hebbachi A, Gibbons GF. Inactivation of microsomal triglyceride transfer protein impairs the normal redistribution but not the turnover of newly synthesized glycerolipid in the cytosol, endoplasmic reticulum and Golgi of primary rat hepatocytes. Biochim Biophys Acta 1999; 1441: 36-50.
    • (1999) Biochim Biophys Acta , vol.1441 , pp. 36-50
    • Hebbachi, A.1    Gibbons, G.F.2
  • 126
    • 0032830541 scopus 로고    scopus 로고
    • Suppression of cytosolic triacylglycerol recruitment for very low density lipoprotein assembly by inactivation of microsomal triglyceride transfer protein results in a delayed removal of apoB-48 and apoB-100 from microsomal and Golgi membranes of primary rat hepatocytes
    • Hebbachi AM, Brown AM, Gibbons GF. Suppression of cytosolic triacylglycerol recruitment for very low density lipoprotein assembly by inactivation of microsomal triglyceride transfer protein results in a delayed removal of apoB-48 and apoB-100 from microsomal and Golgi membranes of primary rat hepatocytes. J Lipid Res 1999; 40: 1758-68.
    • (1999) J Lipid Res , vol.40 , pp. 1758-1768
    • Hebbachi, A.M.1    Brown, A.M.2    Gibbons, G.F.3
  • 127
    • 0031882256 scopus 로고    scopus 로고
    • Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: Interaction with saturated and unsaturated dietary fatty acids
    • van Greevenbroek MM, Robertus-Teunissen MG, Erkelens DW, de Bruin TW. Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: interaction with saturated and unsaturated dietary fatty acids. J Lipid Res 1998; 39: 173-85.
    • (1998) J Lipid Res , vol.39 , pp. 173-185
    • van Greevenbroek, M.M.1    Robertus-Teunissen, M.G.2    Erkelens, D.W.3    de Bruin, T.W.4
  • 128
    • 0242290829 scopus 로고    scopus 로고
    • CP-346086: An MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans
    • Chandler CE, Wilder DE, Pettini JL, et al. CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans. J Lipid Res 2003; 44: 1887-901.
    • (2003) J Lipid Res , vol.44 , pp. 1887-1901
    • Chandler, C.E.1    Wilder, D.E.2    Pettini, J.L.3
  • 129
    • 33846151732 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia
    • Cuchel M, Bloedon LT, Szapary PO, et al. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. N Engl J Med 2007; 356: 148-56.
    • (2007) N Engl J Med , vol.356 , pp. 148-156
    • Cuchel, M.1    Bloedon, L.T.2    Szapary, P.O.3
  • 130
    • 48349088178 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
    • Samaha FF, McKenney J, Bloedon LT, et al. Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nat Clin Pract Cardiovasc Med 2008; 5: 497-505.
    • (2008) Nat Clin Pract Cardiovasc Med , vol.5 , pp. 497-505
    • Samaha, F.F.1    McKenney, J.2    Bloedon, L.T.3
  • 131
    • 77749240456 scopus 로고    scopus 로고
    • Lomitapide, a microsomal triglyceride transfer protein inhibitor for the treatment of hypercholesterolemia
    • Rizzo M. Lomitapide, a microsomal triglyceride transfer protein inhibitor for the treatment of hypercholesterolemia. IDrugs 2010; 13: 103-11.
    • (2010) IDrugs , vol.13 , pp. 103-111
    • Rizzo, M.1
  • 132
    • 19444384186 scopus 로고    scopus 로고
    • Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: Involvement of the inhibition of postprandial triglyceride elevation
    • Ueshima K, Akihisa-Umeno H, Nagayoshi A, et al. Implitapide, a microsomal triglyceride transfer protein inhibitor, reduces progression of atherosclerosis in apolipoprotein E knockout mice fed a Western-type diet: involvement of the inhibition of postprandial triglyceride elevation. Biol Pharm Bull 2005; 28: 247-52.
    • (2005) Biol Pharm Bull , vol.28 , pp. 247-252
    • Ueshima, K.1    Akihisa-Umeno, H.2    Nagayoshi, A.3
  • 133
    • 0035924183 scopus 로고    scopus 로고
    • Diaminoindanes as microsomal triglyceride transfer protein inhibitors
    • Ksander GM, deJesus R, Yuan A, et al. Diaminoindanes as microsomal triglyceride transfer protein inhibitors. J Med Chem 2001; 44: 4677-87.
    • (2001) J Med Chem , vol.44 , pp. 4677-4687
    • Ksander, G.M.1    deJesus, R.2    Yuan, A.3
  • 134
    • 0037085471 scopus 로고    scopus 로고
    • Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury
    • Bjorkegren J, Beigneux A, Bergo MO, et al. Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury. J Biol Chem 2002; 277: 5476-83.
    • (2002) J Biol Chem , vol.277 , pp. 5476-5483
    • Bjorkegren, J.1    Beigneux, A.2    Bergo, M.O.3
  • 135
    • 79960411842 scopus 로고    scopus 로고
    • Hyperuricaemia and non-alcoholic fatty liver disease (NAFLD): A relationship with implications for vascular risk?
    • Katsiki N, Athyros VG, Karagiannis A, Mikhailidis DP. Hyperuricaemia and non-alcoholic fatty liver disease (NAFLD): a relationship with implications for vascular risk? Curr Vasc Pharmacol 2011; 9: 698-705.
    • (2011) Curr Vasc Pharmacol , vol.9 , pp. 698-705
    • Katsiki, N.1    Athyros, V.G.2    Karagiannis, A.3    Mikhailidis, D.P.4
  • 137
    • 78649890465 scopus 로고    scopus 로고
    • Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: A post-hoc analysis
    • Athyros VG, Tziomalos K, Gossios TD, et al. Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis. Lancet 2010; 376: 1916-22.
    • (2010) Lancet , vol.376 , pp. 1916-1922
    • Athyros, V.G.1    Tziomalos, K.2    Gossios, T.D.3
  • 138
    • 33845922351 scopus 로고    scopus 로고
    • Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis
    • Spann NJ, Kang S, Li AC, et al. Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis. J Biol Chem 2006; 281: 33066-77.
    • (2006) J Biol Chem , vol.281 , pp. 33066-33077
    • Spann, N.J.1    Kang, S.2    Li, A.C.3
  • 139
    • 60449115612 scopus 로고    scopus 로고
    • Discovery of benzothiazole derivatives as efficacious and enterocyte-specific MTP inhibitors
    • Vu CB, Milne JC, Carney DP, et al. Discovery of benzothiazole derivatives as efficacious and enterocyte-specific MTP inhibitors. Bioorg Med Chem Lett 2009; 19: 1416-20.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 1416-1420
    • Vu, C.B.1    Milne, J.C.2    Carney, D.P.3
  • 140
    • 79958222144 scopus 로고    scopus 로고
    • New lipid modulating drugs: The role of microsomal transport protein inhibitors
    • Rizzo M, Wierzbicki AS. New lipid modulating drugs: the role of microsomal transport protein inhibitors. Curr Pharm Des 2011; 17: 943-9.
    • (2011) Curr Pharm Des , vol.17 , pp. 943-949
    • Rizzo, M.1    Wierzbicki, A.S.2
  • 141
    • 37549037023 scopus 로고    scopus 로고
    • Orlistat-associated adverse effects and drug interactions: A critical review
    • Filippatos TD, Derdemezis CS, Gazi IF, et al. Orlistat-associated adverse effects and drug interactions: a critical review. Drug Saf 2008; 31: 53-65.
    • (2008) Drug Saf , vol.31 , pp. 53-65
    • Filippatos, T.D.1    Derdemezis, C.S.2    Gazi, I.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.