ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver

Circulation

Volumn 110, Issue 14, 2004, Pages 2017-2023

  Parini, Paolo ^a,b   Davis, Matthew ^c   Lada, Aaron T ^c   Erickson, Sandra K ^d,e   Wright, Teresa L ^d,e   Gustafsson, Ulf ^f   Sahlin, Staffan ^f   Einarsson, Curt ^b   Eriksson, Mats ^a,b   Angelin, Bo ^a,b   Tomoda, Hiroshi ^g   Omura, Satoshi ^g   Willingham, Mark C ^c   Rudel, Lawrence L ^c  

^a Ctr for Metab and Endocrinology   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f DANDERYD HOSPITAL   (Sweden)

^g KITASATO UNIVERSITY   (Japan)

Author keywords

Cholesterol; Genes; Lipids; Metabolism

Indexed keywords

CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ACYLTRANSFERASE 2; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; PYRIPYROPENE A; UNCLASSIFIED DRUG;

ACAT1 GENE; ACAT2 GENE; ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL ESTERIFICATION; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; GENE; HUMAN; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; IMMUNOHISTOLOGY; KUPFFER CELL; LIVER; LIVER BIOPSY; LIVER CELL; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD;

ADOLESCENT; ADULT; AGED; ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHILD; CHOLECYSTITIS; CHOLESTEROL; CHOLESTEROL ESTERS; DIETARY FATS; ENZYME INDUCTION; FEMALE; HEPATOCYTES; HUMANS; KUPFFER CELLS; LIVER DISEASES; MALE; MICROSOMES, LIVER; MIDDLE AGED; PYRIDINES; RNA, MESSENGER; SESQUITERPENES; SPECIES SPECIFICITY; STEROL O-ACYLTRANSFERASE;

EID: 20844451381     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000143163.76212.0B     Document Type: Article

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