-
1
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit R.S., Kuhn C.M., Cochrane C., McCubbin J.A., and Feinglos M.N. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37 (1988) 1163-1167
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
2
-
-
9644260361
-
Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice
-
Almind K., and Kahn C.R. Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes 53 (2004) 3274-3285
-
(2004)
Diabetes
, vol.53
, pp. 3274-3285
-
-
Almind, K.1
Kahn, C.R.2
-
4
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., and Ferrante Jr. A.W. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112 (2003) 1796-1808
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
5
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., Sole J., Nichols A., Ross J.S., Tartaglia L.A., and Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112 (2003) 1821-1830
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
6
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
-
Alexander W.S., and Hilton D.J. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu. Rev. Immunol. 22 (2004) 503-529
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
7
-
-
0034717062
-
SOCS-3 is an insulin-induced negative regulator of insulin signaling
-
Emanuelli B., Peraldi P., Filloux C., Sawka-Verhelle D., Hilton D., and Van Obberghen E. SOCS-3 is an insulin-induced negative regulator of insulin signaling. J. Biol. Chem. 275 (2000) 15985-15991
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15985-15991
-
-
Emanuelli, B.1
Peraldi, P.2
Filloux, C.3
Sawka-Verhelle, D.4
Hilton, D.5
Van Obberghen, E.6
-
8
-
-
0035930605
-
SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice
-
Emanuelli B., Peraldi P., Filloux C., Chavey C., Freidinger K., Hilton D.J., Hotamisligil G.S., and Van Obberghen E. SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice. J. Biol. Chem. 276 (2001) 47944-47949
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47944-47949
-
-
Emanuelli, B.1
Peraldi, P.2
Filloux, C.3
Chavey, C.4
Freidinger, K.5
Hilton, D.J.6
Hotamisligil, G.S.7
Van Obberghen, E.8
-
9
-
-
0036830636
-
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
-
Rui L., Yuan M., Frantz D., Shoelson S., and White M.F. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J. Biol. Chem. 277 (2002) 42394-42398
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42394-42398
-
-
Rui, L.1
Yuan, M.2
Frantz, D.3
Shoelson, S.4
White, M.F.5
-
10
-
-
0035854723
-
Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance
-
Mooney R.A., Senn J., Cameron S., Inamdar N., Boivin L.M., Shang Y., and Furlanetto R.W. Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance. J. Biol. Chem. 276 (2001) 25889-25893
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25889-25893
-
-
Mooney, R.A.1
Senn, J.2
Cameron, S.3
Inamdar, N.4
Boivin, L.M.5
Shang, Y.6
Furlanetto, R.W.7
-
11
-
-
2942628012
-
Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms
-
Ueki K., Kondo T., and Kahn C.R. Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms. Mol. Cell. Biol. 24 (2004) 5434-5446
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5434-5446
-
-
Ueki, K.1
Kondo, T.2
Kahn, C.R.3
-
12
-
-
4344698092
-
Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients
-
Rieusset J., Bouzakri K., Chevillotte E., Ricard N., Jacquet D., Bastard J.P., Laville M., and Vidal H. Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients. Diabetes 53 (2004) 2232-2241
-
(2004)
Diabetes
, vol.53
, pp. 2232-2241
-
-
Rieusset, J.1
Bouzakri, K.2
Chevillotte, E.3
Ricard, N.4
Jacquet, D.5
Bastard, J.P.6
Laville, M.7
Vidal, H.8
-
13
-
-
3142782772
-
Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3
-
Howard J.K., Cave B.J., Oksanen L.J., Tzameli I., Bjorbaek C., and Flier J.S. Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3. Nat. Med. 10 (2004) 734-738
-
(2004)
Nat. Med.
, vol.10
, pp. 734-738
-
-
Howard, J.K.1
Cave, B.J.2
Oksanen, L.J.3
Tzameli, I.4
Bjorbaek, C.5
Flier, J.S.6
-
14
-
-
3142723983
-
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
-
Mori H., Hanada R., Hanada T., Aki D., Mashima R., Nishinakamura H., Torisu T., Chien K.R., Yasukawa H., and Yoshimura A. Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity. Nat. Med. 10 (2004) 739-743
-
(2004)
Nat. Med.
, vol.10
, pp. 739-743
-
-
Mori, H.1
Hanada, R.2
Hanada, T.3
Aki, D.4
Mashima, R.5
Nishinakamura, H.6
Torisu, T.7
Chien, K.R.8
Yasukawa, H.9
Yoshimura, A.10
-
15
-
-
3142723189
-
Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
-
Ueki K., Kondo T., Tseng Y.H., and Kahn C.R. Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. Proc. Natl. Acad. Sci. USA 101 (2004) 10422-10427
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10422-10427
-
-
Ueki, K.1
Kondo, T.2
Tseng, Y.H.3
Kahn, C.R.4
-
16
-
-
0035862334
-
Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation
-
Kawazoe Y., Naka T., Fujimoto M., Kohzaki H., Morita Y., Narazaki M., Okumura K., Saitoh H., Nakagawa R., Uchiyama Y., Akira S., and Kishimoto T. Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation. J. Exp. Med. 193 (2001) 263-269
-
(2001)
J. Exp. Med.
, vol.193
, pp. 263-269
-
-
Kawazoe, Y.1
Naka, T.2
Fujimoto, M.3
Kohzaki, H.4
Morita, Y.5
Narazaki, M.6
Okumura, K.7
Saitoh, H.8
Nakagawa, R.9
Uchiyama, Y.10
Akira, S.11
Kishimoto, T.12
-
17
-
-
0033520467
-
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
-
Marine J.C., Topham D.J., McKay C., Wang D., Parganas E., Stravopodis D., Yoshimura A., and Ihle J.N. SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell 98 (1999) 609-616
-
(1999)
Cell
, vol.98
, pp. 609-616
-
-
Marine, J.C.1
Topham, D.J.2
McKay, C.3
Wang, D.4
Parganas, E.5
Stravopodis, D.6
Yoshimura, A.7
Ihle, J.N.8
-
18
-
-
0347985272
-
Obesity-induced inflammatory changes in adipose tissue
-
Wellen K.E., and Hotamisligil G.S. Obesity-induced inflammatory changes in adipose tissue. J. Clin. Invest. 112 (2003) 1785-1788
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1785-1788
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
19
-
-
37249093922
-
-
P. Lebrun, E. Van Obberghen, SOCS proteins causing trouble in insulin action, Acta Physiol. (Oxf.) 192 (2008) 29-36.
-
P. Lebrun, E. Van Obberghen, SOCS proteins causing trouble in insulin action, Acta Physiol. (Oxf.) 192 (2008) 29-36.
-
-
-
-
20
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
-
Cai D., Yuan M., Frantz D.F., Melendez P.A., Hansen L., Lee J., and Shoelson S.E. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat. Med. 11 (2005) 183-190
-
(2005)
Nat. Med.
, vol.11
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
21
-
-
9444248788
-
The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells
-
Emanuelli B., Glondu M., Filloux C., Peraldi P., and Van Obberghen E. The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells. Diabetes 53 Suppl. 3 (2004) S97-S103
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Emanuelli, B.1
Glondu, M.2
Filloux, C.3
Peraldi, P.4
Van Obberghen, E.5
|