-
1
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., Sole J., Nichols A., Ross J.S., Tartaglia L.A., and Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112 (2003) 1821-1830
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
2
-
-
22844437863
-
Endocrine and signalling role of adipose tissue: new perspectives on fat
-
Trayhurn P. Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiol. Scand. 184 (2005) 285-293
-
(2005)
Acta Physiol. Scand.
, vol.184
, pp. 285-293
-
-
Trayhurn, P.1
-
3
-
-
33646572904
-
The metabolic syndrome and adipocytokines
-
Matsuzawa Y. The metabolic syndrome and adipocytokines. FEBS Lett. 580 (2006) 2917-2921
-
(2006)
FEBS Lett.
, vol.580
, pp. 2917-2921
-
-
Matsuzawa, Y.1
-
4
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
-
Hotamisligil G.S., Shargill N.S., and Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259 (1993) 87-91
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
5
-
-
19044393872
-
Adipose tissue inflammation, and cardiovascular disease
-
Berg A.H., and Scherer P.E. Adipose tissue inflammation, and cardiovascular disease. Circ. Res. 96 (2005) 939-949
-
(2005)
Circ. Res.
, vol.96
, pp. 939-949
-
-
Berg, A.H.1
Scherer, P.E.2
-
6
-
-
0034969433
-
Elements of the fibrinolytic system
-
Lijnen H.R. Elements of the fibrinolytic system. Ann. NY Acad. Sci. 936 (2001) 226-236
-
(2001)
Ann. NY Acad. Sci.
, vol.936
, pp. 226-236
-
-
Lijnen, H.R.1
-
7
-
-
0033047930
-
Impact of adipose tissue on plasma plasminogen activator inhibitor-1 in dieting obese women
-
Mavri A., Stegnar M., Krebs M., Sentocnik J.T., Geiger M., and Binder B.R. Impact of adipose tissue on plasma plasminogen activator inhibitor-1 in dieting obese women. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 1582-1587
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 1582-1587
-
-
Mavri, A.1
Stegnar, M.2
Krebs, M.3
Sentocnik, J.T.4
Geiger, M.5
Binder, B.R.6
-
8
-
-
33845951873
-
Bone marrow plasminogen activator inhibitor-1 influences the development of obesity
-
De Taeye B.M., Novitskaya T., Gleaves L., Covington J.W., and Vaughan D.E. Bone marrow plasminogen activator inhibitor-1 influences the development of obesity. J. Biol. Chem. 281 (2006) 32796-32805
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 32796-32805
-
-
De Taeye, B.M.1
Novitskaya, T.2
Gleaves, L.3
Covington, J.W.4
Vaughan, D.E.5
-
9
-
-
0030140458
-
Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease
-
Rollins B.J. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease. Mol. Med. Today 2 (1996) 198-204
-
(1996)
Mol. Med. Today
, vol.2
, pp. 198-204
-
-
Rollins, B.J.1
-
10
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue insulin resistance, and hepatic steatosis in obesity
-
Kanda H., Tateya S., Tamori Y., Kotani K., Hiasa K., Kitazawa R., Kitazawa S., Miyachi H., Maeda S., Egashira K., and Kasuga M. MCP-1 contributes to macrophage infiltration into adipose tissue insulin resistance, and hepatic steatosis in obesity. J. Clin. Invest. 116 (2006) 1494-1505
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
Kitazawa, R.6
Kitazawa, S.7
Miyachi, H.8
Maeda, S.9
Egashira, K.10
Kasuga, M.11
-
12
-
-
0037453716
-
Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis
-
Sordella R., Jiang W., Chen G.C., Curto M., and Settleman J. Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell 113 (2003) 147-158
-
(2003)
Cell
, vol.113
, pp. 147-158
-
-
Sordella, R.1
Jiang, W.2
Chen, G.C.3
Curto, M.4
Settleman, J.5
-
13
-
-
0037677767
-
Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors
-
Iwaki M., Matsuda M., Maeda N., Funahashi T., Matsuzawa Y., Makishima M., and Shimomura I. Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52 (2003) 1655-1663
-
(2003)
Diabetes
, vol.52
, pp. 1655-1663
-
-
Iwaki, M.1
Matsuda, M.2
Maeda, N.3
Funahashi, T.4
Matsuzawa, Y.5
Makishima, M.6
Shimomura, I.7
-
14
-
-
0033081753
-
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
-
Ren X.D., Kiosses W.B., and Schwartz M.A. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 18 (1999) 578-585
-
(1999)
EMBO J.
, vol.18
, pp. 578-585
-
-
Ren, X.D.1
Kiosses, W.B.2
Schwartz, M.A.3
-
15
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
Furukawa S., Fujita T., Shimabukuro M., Iwaki M., Yamada Y., Nakajima Y., Nakayama O., Makishima M., Matsuda M., and Shimomura I. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114 (2004) 1752-1761
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
16
-
-
0032498528
-
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
-
Matsui T., Maeda M., Doi Y., Yonemura S., Amano M., Kaibuchi K., and Tsukita S. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J. Cell Biol. 140 (1998) 647-657
-
(1998)
J. Cell Biol.
, vol.140
, pp. 647-657
-
-
Matsui, T.1
Maeda, M.2
Doi, Y.3
Yonemura, S.4
Amano, M.5
Kaibuchi, K.6
Tsukita, S.7
-
17
-
-
33748195107
-
A rapid reversible and tunable method to regulate protein function in living cells using synthetic small molecules
-
Banaszynski L.A., Chen L.C., Maynard-Smith L.A., Ooi A.G., and Wandless T.J. A rapid reversible and tunable method to regulate protein function in living cells using synthetic small molecules. Cell 126 (2006) 995-1004
-
(2006)
Cell
, vol.126
, pp. 995-1004
-
-
Banaszynski, L.A.1
Chen, L.C.2
Maynard-Smith, L.A.3
Ooi, A.G.4
Wandless, T.J.5
-
18
-
-
34548297903
-
A directed approach for engineering conditional protein stability using biologically silent small molecules
-
Maynard-Smith L.A., Chen L.C., Banaszynski L.A., Ooi A.G., and Wandless T.J. A directed approach for engineering conditional protein stability using biologically silent small molecules. J. Biol. Chem. 282 (2007) 24866-24872
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24866-24872
-
-
Maynard-Smith, L.A.1
Chen, L.C.2
Banaszynski, L.A.3
Ooi, A.G.4
Wandless, T.J.5
-
19
-
-
0036469263
-
Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism
-
Neumann H., Schweigreiter R., Yamashita T., Rosenkranz K., Wekerle H., and Barde Y.A. Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism. J. Neurosci. 22 (2002) 854-862
-
(2002)
J. Neurosci.
, vol.22
, pp. 854-862
-
-
Neumann, H.1
Schweigreiter, R.2
Yamashita, T.3
Rosenkranz, K.4
Wekerle, H.5
Barde, Y.A.6
-
20
-
-
32844469380
-
Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization
-
Ransom R.F., Lam N.G., Hallett M.A., Atkinson S.J., and Smoyer W.E. Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization. Kidney Int. 68 (2005) 2473-2483
-
(2005)
Kidney Int.
, vol.68
, pp. 2473-2483
-
-
Ransom, R.F.1
Lam, N.G.2
Hallett, M.A.3
Atkinson, S.J.4
Smoyer, W.E.5
-
21
-
-
25144500035
-
Role of Rho-kinase in regulation of insulin action and glucose homeostasis
-
Furukawa N., Ongusaha P., Jahng W.J., Araki K., Choi C.S., Kim H.J., Lee Y.H., Kaibuchi K., Kahn B.B., Masuzaki H., Kim J.K., Lee S.W., and Kim Y.B. Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metab. 2 (2005) 119-129
-
(2005)
Cell Metab.
, vol.2
, pp. 119-129
-
-
Furukawa, N.1
Ongusaha, P.2
Jahng, W.J.3
Araki, K.4
Choi, C.S.5
Kim, H.J.6
Lee, Y.H.7
Kaibuchi, K.8
Kahn, B.B.9
Masuzaki, H.10
Kim, J.K.11
Lee, S.W.12
Kim, Y.B.13
-
22
-
-
1842531067
-
Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes
-
Fasshauer M., Klein J., Kralisch S., Klier M., Lossner U., Bluher M., and Paschke R. Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 317 (2004) 598-604
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.317
, pp. 598-604
-
-
Fasshauer, M.1
Klein, J.2
Kralisch, S.3
Klier, M.4
Lossner, U.5
Bluher, M.6
Paschke, R.7
-
23
-
-
0033063052
-
TNF-alpha Insulin alone synergistically induce plasminogen activator inhibitor-1 expression in adipocytes
-
Sakamoto T., Woodcock-Mitchell J., Marutsuka K., Mitchell J.J., Sobel B.E., and Fujii S. TNF-alpha Insulin alone synergistically induce plasminogen activator inhibitor-1 expression in adipocytes. Am. J. Physiol. 276 (1999) C1391-C1397
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Sakamoto, T.1
Woodcock-Mitchell, J.2
Marutsuka, K.3
Mitchell, J.J.4
Sobel, B.E.5
Fujii, S.6
-
24
-
-
31444447850
-
Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes
-
Chen B., Lam K.S., Wang Y., Wu D., Lam M.C., Shen J., Wong L., Hoo R.L., Zhang J., and Xu A. Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes. Biochem. Biophys. Res. Commun. 341 (2006) 549-556
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.341
, pp. 549-556
-
-
Chen, B.1
Lam, K.S.2
Wang, Y.3
Wu, D.4
Lam, M.C.5
Shen, J.6
Wong, L.7
Hoo, R.L.8
Zhang, J.9
Xu, A.10
-
25
-
-
35348943931
-
Nitric oxide dysregulates adipocytokine expression in 3T3-L1 adipocytes
-
Nozaki M., Fukuhara A., Segawa K., Okuno Y., Abe M., Hosogai N., Matsuda M., Komuro R., and Shimomura I. Nitric oxide dysregulates adipocytokine expression in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 364 (2007) 33-39
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.364
, pp. 33-39
-
-
Nozaki, M.1
Fukuhara, A.2
Segawa, K.3
Okuno, Y.4
Abe, M.5
Hosogai, N.6
Matsuda, M.7
Komuro, R.8
Shimomura, I.9
-
26
-
-
34548853983
-
Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I converting enzyme levels
-
Rivera P., Ocaranza M.P., Lavandero S., and Jalil J.E. Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I converting enzyme levels. Hypertension 50 (2007) 792-798
-
(2007)
Hypertension
, vol.50
, pp. 792-798
-
-
Rivera, P.1
Ocaranza, M.P.2
Lavandero, S.3
Jalil, J.E.4
-
27
-
-
0037334137
-
Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: role in the Ca2+ sensitization of myosin light chain20 phosphorylation
-
Hunter I., Cobban H.J., Vandenabeele P., MacEwan D.J., and Nixon G.F. Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: role in the Ca2+ sensitization of myosin light chain20 phosphorylation. Mol. Pharmacol. 63 (2003) 714-721
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 714-721
-
-
Hunter, I.1
Cobban, H.J.2
Vandenabeele, P.3
MacEwan, D.J.4
Nixon, G.F.5
-
28
-
-
33845921822
-
Spatial compartmentalization of tumor necrosis factor (TNF) receptor 1-dependent signaling pathways in human airway smooth muscle cells. Lipid rafts are essential for TNF-alpha-mediated activation of RhoA but dispensable for the activation of the NF-kappaB MAPK pathways
-
Hunter I., and Nixon G.F. Spatial compartmentalization of tumor necrosis factor (TNF) receptor 1-dependent signaling pathways in human airway smooth muscle cells. Lipid rafts are essential for TNF-alpha-mediated activation of RhoA but dispensable for the activation of the NF-kappaB MAPK pathways. J. Biol. Chem. 281 (2006) 34705-34715
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 34705-34715
-
-
Hunter, I.1
Nixon, G.F.2
-
29
-
-
0034988809
-
Differential effect of MLC kinase in TNF-alpha-induced endothelial cell apoptosis and barrier dysfunction
-
Petrache I., Verin A.D., Crow M.T., Birukova A., Liu F., and Garcia J.G. Differential effect of MLC kinase in TNF-alpha-induced endothelial cell apoptosis and barrier dysfunction. Am. J. Physiol. Lung Cell. Mol. Physiol. 280 (2001) L1168-L1178
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.280
-
-
Petrache, I.1
Verin, A.D.2
Crow, M.T.3
Birukova, A.4
Liu, F.5
Garcia, J.G.6
-
30
-
-
40449087466
-
Activation of Rho kinase by TNF-alpha is required for JNK activation in human pulmonary microvascular endothelial cells
-
Mong P.Y., Petrulio C., Kaufman H.L., and Wang Q. Activation of Rho kinase by TNF-alpha is required for JNK activation in human pulmonary microvascular endothelial cells. J. Immunol. 180 (2008) 550-558
-
(2008)
J. Immunol.
, vol.180
, pp. 550-558
-
-
Mong, P.Y.1
Petrulio, C.2
Kaufman, H.L.3
Wang, Q.4
-
31
-
-
1842426730
-
Cell shape cytoskeletal tension and RhoA regulate stem cell lineage commitment
-
McBeath R., Pirone D.M., Nelson C.M., Bhadriraju K., and Chen C.S. Cell shape cytoskeletal tension and RhoA regulate stem cell lineage commitment. Dev. Cell 6 (2004) 483-495
-
(2004)
Dev. Cell
, vol.6
, pp. 483-495
-
-
McBeath, R.1
Pirone, D.M.2
Nelson, C.M.3
Bhadriraju, K.4
Chen, C.S.5
-
32
-
-
0032489871
-
Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation
-
Aoki H., Izumo S., and Sadoshima J. Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation. Circ. Res. 82 (1998) 666-676
-
(1998)
Circ. Res.
, vol.82
, pp. 666-676
-
-
Aoki, H.1
Izumo, S.2
Sadoshima, J.3
-
33
-
-
0032500843
-
Interleukin-1 beta reactive oxygen species mediate activation of c-Jun NH2-terminal kinases in human epithelial cells by two independent pathways
-
Roberts M.L., and Cowsert L.M. Interleukin-1 beta reactive oxygen species mediate activation of c-Jun NH2-terminal kinases in human epithelial cells by two independent pathways. Biochem. Biophys. Res. Commun. 251 (1998) 166-172
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.251
, pp. 166-172
-
-
Roberts, M.L.1
Cowsert, L.M.2
|