Genetic interactions of STAT3 and anticancer drug development

Cancers

Volumn 6, Issue 1, 2014, Pages 494-525

  Fang, Bingliang ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Cancer; Drug development; EGFR; Genetic interaction; Ras; Reactive oxygen species; Redox; STAT3; Synthetic lethality

Indexed keywords

5 CHLORO N2 [1 (5 FLUORO 2 PYRIMIDINYL)ETHYL] N4 (5 METHYL 1H PYRAZOL 3 YL) 2,4 PYRIMIDINEDIAMINE; AFATINIB; ANTINEOPLASTIC AGENT; CETUXIMAB; DACOMITINIB; DASATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; INCB 16562; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MANGANESE SUPEROXIDE DISMUTASE; PARTHENOLIDE; PHOSPHOLIPASE C GAMMA; RAS PROTEIN; RUXOLITINIB; SELUMETINIB; STAT3 PROTEIN; STAT5 PROTEIN; TOFACITINIB; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; B CELL LYMPHOMA; BLADDER CANCER; CARCINOGENESIS; CATALYSIS; COLORECTAL CANCER; DRUG EFFICACY; DRUG POTENCY; DRUG RESEARCH; EPITHELIAL MESENCHYMAL TRANSITION; GENE DISRUPTION; GENE INTERACTION; GENE MUTATION; GENETIC PREDISPOSITION; GLIOMA; HEAD AND NECK CANCER; HUMAN; HYPERIMMUNOGLOBULINEMIA; LEUKEMIA; LUNG ADENOCARCINOMA; LYMPHOMA; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MYELOFIBROSIS; NONHUMAN; OSTEOSARCOMA; OXIDATION REDUCTION REACTION; PANCREAS CANCER; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA; SURVIVAL RATE; T LYMPHOCYTE;

EID: 84896913973     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers6010494     Document Type: Review

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