-
1
-
-
0028303977
-
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
-
Akira S, Nishio Y, Inoue M, et al. Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 1994;77:63-71.
-
(1994)
Cell
, vol.77
, pp. 63-71
-
-
Akira, S.1
Nishio, Y.2
Inoue, M.3
-
2
-
-
0028274299
-
The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family
-
Wegenka UM, Lutticken C, Buschmann J, et al. The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family. Mol Cell Biol 1994;14:3186-96.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3186-3196
-
-
Wegenka, U.M.1
Lutticken, C.2
Buschmann, J.3
-
3
-
-
0031919849
-
Jaks and STATs: Biological implications
-
Leonard WJ, O'Shea JJ. Jaks and STATs: biological implications. Annu Rev Immunol 1998;16:293-322.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
4
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga T, Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 1997;15:797-819.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
5
-
-
0028349735
-
Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong Z, Wen Z, Darnell JE, Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994;264:95-8.
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell Jr, J.E.3
-
6
-
-
0037192781
-
Transcriptional stimulation of the surfactant protein B gene by STAT3 in respiratory epithelial cells
-
Yan C, Naltner A, Martin M, Naltner M, Fangman JM, Gurel O. Transcriptional stimulation of the surfactant protein B gene by STAT3 in respiratory epithelial cells. J Biol Chem 2002;277:10967-72.
-
(2002)
J Biol Chem
, vol.277
, pp. 10967-10972
-
-
Yan, C.1
Naltner, A.2
Martin, M.3
Naltner, M.4
Fangman, J.M.5
Gurel, O.6
-
7
-
-
2542430085
-
Synergy between signal transducer and activator of transcription 3 and retinoic acid receptor-α in regulation of the surfactant protein B gene in the lung
-
Yang L, Lian X, Cowen A, Xu H, Du H, Yan C. Synergy between signal transducer and activator of transcription 3 and retinoic acid receptor-α in regulation of the surfactant protein B gene in the lung. Mol Endocrinol 2004;18:1520-32.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 1520-1532
-
-
Yang, L.1
Lian, X.2
Cowen, A.3
Xu, H.4
Du, H.5
Yan, C.6
-
9
-
-
21544473172
-
Targeting STAT3 affects melanoma on multiple fronts
-
Kortylewski M, Jove R, Yu H. Targeting STAT3 affects melanoma on multiple fronts. Cancer Metastasis Rev 2005;24:315-27.
-
(2005)
Cancer Metastasis Rev
, vol.24
, pp. 315-327
-
-
Kortylewski, M.1
Jove, R.2
Yu, H.3
-
10
-
-
28544438023
-
Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
-
Haura EB, Zheng Z, Song L, Cantor A, Bepler G. Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res 2005;11:8288-94.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8288-8294
-
-
Haura, E.B.1
Zheng, Z.2
Song, L.3
Cantor, A.4
Bepler, G.5
-
11
-
-
33746238953
-
Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion
-
Yeh HH, Lai WW, Chen HH, Liu HS, Su WC. Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion. Oncogene 2006;25:4300-9.
-
(2006)
Oncogene
, vol.25
, pp. 4300-4309
-
-
Yeh, H.H.1
Lai, W.W.2
Chen, H.H.3
Liu, H.S.4
Su, W.C.5
-
12
-
-
19444385692
-
Stat3 regulates genes common to both wound healing and cancer
-
Dauer DJ, Ferraro B, Song L, et al. Stat3 regulates genes common to both wound healing and cancer. Oncogene 2005;24:3397-408.
-
(2005)
Oncogene
, vol.24
, pp. 3397-3408
-
-
Dauer, D.J.1
Ferraro, B.2
Song, L.3
-
13
-
-
23944435400
-
IL-6 induces neuroendocrine dedifferentiation and cell proliferation in non-small cell lung cancer cells
-
Chang KT, Tsai CM, Chiou YC, Chiu CH, Jeng KS, Huang CY. IL-6 induces neuroendocrine dedifferentiation and cell proliferation in non-small cell lung cancer cells. Am J Physiol Lung Cell Mol Physiol 2005;289:L446-53.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
-
-
Chang, K.T.1
Tsai, C.M.2
Chiou, Y.C.3
Chiu, C.H.4
Jeng, K.S.5
Huang, C.Y.6
-
14
-
-
0038505594
-
Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC)
-
Mukohara T, Kudoh S, Yamauchi S, et al. Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC). Lung Cancer 2003;41:123-30.
-
(2003)
Lung Cancer
, vol.41
, pp. 123-130
-
-
Mukohara, T.1
Kudoh, S.2
Yamauchi, S.3
-
15
-
-
0037699512
-
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells
-
Song L, Turkson J, Karras JG, Jove R, Haura EB. Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells. Oncogene 2003;22:4150-65.
-
(2003)
Oncogene
, vol.22
, pp. 4150-4165
-
-
Song, L.1
Turkson, J.2
Karras, J.G.3
Jove, R.4
Haura, E.B.5
-
16
-
-
28644445445
-
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
-
Kortylewski M, Kujawski M, Wang T, et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med 2005;11:1314-21.
-
(2005)
Nat Med
, vol.11
, pp. 1314-1321
-
-
Kortylewski, M.1
Kujawski, M.2
Wang, T.3
-
18
-
-
1642379630
-
Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung
-
Lian X, Yan C, Yang L, Xu Y, Du H. Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung. Am J Physiol Lung Cell Mol Physiol 2004;286:L801-7.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.286
-
-
Lian, X.1
Yan, C.2
Yang, L.3
Xu, Y.4
Du, H.5
-
19
-
-
24044508876
-
Neutral lipids and peroxisome proliferator-activated receptor-γ control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice
-
Lian X, Yan C, Qin Y, Knox L, Li T, Du H. Neutral lipids and peroxisome proliferator-activated receptor-γ control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice. Am J Pathol 2005;167:813-21.
-
(2005)
Am J Pathol
, vol.167
, pp. 813-821
-
-
Lian, X.1
Yan, C.2
Qin, Y.3
Knox, L.4
Li, T.5
Du, H.6
-
20
-
-
21044459500
-
Overexpression of Stat3C in pulmonary epithelium protects against hyperoxic lung injury
-
Lian X, Qin Y, Hossain SA, et al. Overexpression of Stat3C in pulmonary epithelium protects against hyperoxic lung injury. J Immunol 2005;174:7250-6.
-
(2005)
J Immunol
, vol.174
, pp. 7250-7256
-
-
Lian, X.1
Qin, Y.2
Hossain, S.A.3
-
21
-
-
22144492213
-
IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation
-
McLoughlin RM, Jenkins BJ, Grail D, et al. IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation. Proc Natl Acad Sci U S A 2005;102:9589-94.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9589-9594
-
-
McLoughlin, R.M.1
Jenkins, B.J.2
Grail, D.3
-
22
-
-
0032213273
-
Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell-specific Stat3-deficient mice
-
Takeda K, Kaisho T, Yoshida N, Takeda J, Kishimoto T, Akira S. Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J Immunol 1998;161:4652-60.
-
(1998)
J Immunol
, vol.161
, pp. 4652-4660
-
-
Takeda, K.1
Kaisho, T.2
Yoshida, N.3
Takeda, J.4
Kishimoto, T.5
Akira, S.6
-
23
-
-
33748082302
-
Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor promote malignant growth of cells from head and neck squamous cell carcinomas in vivo
-
Gutschalk CM, Herold-Mende CC, Fusenig NE, Mueller MM. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor promote malignant growth of cells from head and neck squamous cell carcinomas in vivo. Cancer Res 2006;66:8026-36.
-
(2006)
Cancer Res
, vol.66
, pp. 8026-8036
-
-
Gutschalk, C.M.1
Herold-Mende, C.C.2
Fusenig, N.E.3
Mueller, M.M.4
-
24
-
-
27744472334
-
Macrophage migration and gene expression in response to tumor hypoxia
-
Murdoch C, Lewis CE. Macrophage migration and gene expression in response to tumor hypoxia. Int J Cancer 2005;117:701-8.
-
(2005)
Int J Cancer
, vol.117
, pp. 701-708
-
-
Murdoch, C.1
Lewis, C.E.2
-
25
-
-
1342324748
-
Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer
-
Keane MP, Belperio JA, Xue YY, Burdick MD, Strieter RM. Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer. J Immunol 2004;172:2853-60.
-
(2004)
J Immunol
, vol.172
, pp. 2853-2860
-
-
Keane, M.P.1
Belperio, J.A.2
Xue, Y.Y.3
Burdick, M.D.4
Strieter, R.M.5
-
26
-
-
0025038599
-
Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES
-
Schall TJ, Bacon K, Toy KJ, Goeddel DV. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 1990;347:669-71.
-
(1990)
Nature
, vol.347
, pp. 669-671
-
-
Schall, T.J.1
Bacon, K.2
Toy, K.J.3
Goeddel, D.V.4
-
27
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
Niu G, Wright KL, Huang M, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 2002;21:2000-8.
-
(2002)
Oncogene
, vol.21
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
-
28
-
-
34249868449
-
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFκB
-
Yang J, Liao X, Agarwal MK, Barnes L, Auron PE, Stark GR. Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFκB. Genes Dev 2007;21:1396-408.
-
(2007)
Genes Dev
, vol.21
, pp. 1396-1408
-
-
Yang, J.1
Liao, X.2
Agarwal, M.K.3
Barnes, L.4
Auron, P.E.5
Stark, G.R.6
-
29
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006;66:605-12.
-
(2006)
Cancer Res
, vol.66
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
30
-
-
0142151074
-
Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways
-
Borczuk AC, Gorenstein L, Walter KL, Assaad AA, Wang L, Powell CA. Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways. Am J Pathol 2003;163:1949-60.
-
(2003)
Am J Pathol
, vol.163
, pp. 1949-1960
-
-
Borczuk, A.C.1
Gorenstein, L.2
Walter, K.L.3
Assaad, A.A.4
Wang, L.5
Powell, C.A.6
-
31
-
-
0032563948
-
Sonic hedgehog regulates branching morphogenesis in the mammalian lung
-
Pepicelli CV, Lewis PM, McMahon AP. Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol 1998;8:1083-6.
-
(1998)
Curr Biol
, vol.8
, pp. 1083-1086
-
-
Pepicelli, C.V.1
Lewis, P.M.2
McMahon, A.P.3
-
33
-
-
0031034866
-
Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis
-
Bellusci S, Furuta Y, Rush MG, Henderson R, Winnier G, Hogan BL. Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development 1997;124:53-63.
-
(1997)
Development
, vol.124
, pp. 53-63
-
-
Bellusci, S.1
Furuta, Y.2
Rush, M.G.3
Henderson, R.4
Winnier, G.5
Hogan, B.L.6
-
34
-
-
2342481730
-
Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis
-
Li Y, Zhang H, Choi SC, Litingtung Y, Chiang C. Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis. Dev Biol 2004;270:214-31.
-
(2004)
Dev Biol
, vol.270
, pp. 214-231
-
-
Li, Y.1
Zhang, H.2
Choi, S.C.3
Litingtung, Y.4
Chiang, C.5
-
36
-
-
0034695567
-
More surprises in the Hedgehog signaling pathway
-
McMahon AP. More surprises in the Hedgehog signaling pathway. Cell 2000;100:185-8.
-
(2000)
Cell
, vol.100
, pp. 185-188
-
-
McMahon, A.P.1
-
37
-
-
4143129753
-
Role of Sonic hedgehog in patterning of tracheal-bronchial cartilage and the peripheral lung
-
Miller LA, Wert SE, Clark JC, Xu Y, Perl AK, Whitsett JA. Role of Sonic hedgehog in patterning of tracheal-bronchial cartilage and the peripheral lung. Dev Dyn 2004;231:57-71.
-
(2004)
Dev Dyn
, vol.231
, pp. 57-71
-
-
Miller, L.A.1
Wert, S.E.2
Clark, J.C.3
Xu, Y.4
Perl, A.K.5
Whitsett, J.A.6
-
38
-
-
0030057596
-
The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
-
Kimura S, Hara Y, Pineau T, et al. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev 1996;10:60-9.
-
(1996)
Genes Dev
, vol.10
, pp. 60-69
-
-
Kimura, S.1
Hara, Y.2
Pineau, T.3
-
39
-
-
0026340586
-
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain
-
Lazzaro D, Price M, de Felice M, Di Lauro R. The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development 1991;113:1093-104.
-
(1991)
Development
, vol.113
, pp. 1093-1104
-
-
Lazzaro, D.1
Price, M.2
de Felice, M.3
Di Lauro, R.4
-
40
-
-
0026696107
-
Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3α, HNF-3β, HNF-3γ, and HNF-4
-
Avraham KB, Prezioso VR, Chen WS, et al. Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3α, HNF-3β, HNF-3γ, and HNF-4. Genomics 1992;13:264-8.
-
(1992)
Genomics
, vol.13
, pp. 264-268
-
-
Avraham, K.B.1
Prezioso, V.R.2
Chen, W.S.3
-
41
-
-
0027322128
-
Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family
-
Clevidence DE, Overdier DG, Tao W, et al. Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family. Proc Natl Acad Sci U S A 1993;90:3948-52.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 3948-3952
-
-
Clevidence, D.E.1
Overdier, D.G.2
Tao, W.3
-
42
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda K, Noguchi K, Shi W, et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci U S A 1997;94:3801-4.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
Noguchi, K.2
Shi, W.3
|