Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells

Biochemical Pharmacology

Volumn 83, Issue 10, 2012, Pages 1456-1464

  Liu, Xiaoying ^a   Guo, Wei ^a   Wu, Shuhong ^a   Wang, Li ^a   Wang, Ji ^a   Dai, Bingbing ^a   Kim, Edward S ^a   Heymach, John V ^a   Wang, Michael ^a   Girard, Luc ^b   Minna, John ^b   Roth, Jack A ^a   Swisher, Stephen G ^a   Fang, Bingliang ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Drug development; Lung Cancer; Reactive oxygen species; STAT3

Indexed keywords

ANTINEOPLASTIC AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NORDIHYDROGUAIARETIC ACID; NSC 743380; PROTEIN INHIBITOR; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER RESISTANCE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENCY; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN CELL; IC 50; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; HUMANS; LUNG NEOPLASMS; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; STAT3 TRANSCRIPTION FACTOR;

EID: 84862796550     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.02.010     Document Type: Article

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