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Volumn 101, Issue 10, 2003, Pages 4098-4104

Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; ANTILEUKEMIC AGENT; ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; FREE RADICAL; REACTIVE OXYGEN METABOLITE; 2-METHOXYESTRADIOL; DRUG DERIVATIVE; ESTRADIOL; SCAVENGER; SUPEROXIDE;

EID: 0037926836     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-08-2512     Document Type: Article
Times cited : (281)

References (61)
  • 1
    • 0017195881 scopus 로고
    • The excretion of five different 2-hydroxyoestrogen monomethyl ethers in human pregnancy urine
    • Gelbke HP, Knuppen R. The excretion of five different 2-hydroxyoestrogen monomethyl ethers in human pregnancy urine. J Ster Biochem. 1976;7:457-463.
    • (1976) J Ster Biochem , vol.7 , pp. 457-463
    • Gelbke, H.P.1    Knuppen, R.2
  • 2
    • 0028331925 scopus 로고
    • 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site
    • D'Amato RJ, Lin CM, Flynn E, Folkman J, Hamel E. 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site. Proc Natl Acad Sci U S A. 1994;91:3964-3968.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3964-3968
    • D'Amato, R.J.1    Lin, C.M.2    Flynn, E.3    Folkman, J.4    Hamel, E.5
  • 3
    • 0028220858 scopus 로고
    • The endogenous oestrogen metabolite 2-methoxyestradiol inhibits angiogenesis and suppresses tumour growth
    • Fotsis T, Zhang Y, Pepper MS, et al. The endogenous oestrogen metabolite 2-methoxyestradiol inhibits angiogenesis and suppresses tumour growth. Nature. 1994;368:237-239.
    • (1994) Nature , vol.368 , pp. 237-239
    • Fotsis, T.1    Zhang, Y.2    Pepper, M.S.3
  • 5
    • 0032211342 scopus 로고    scopus 로고
    • An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo
    • Kataoka M, Schumacher G, Cristiano RJ, et al. An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo, Cancer Res. 1998;58:4761-4765.
    • (1998) Cancer Res , vol.58 , pp. 4761-4765
    • Kataoka, M.1    Schumacher, G.2    Cristiano, R.J.3
  • 6
    • 0031785593 scopus 로고    scopus 로고
    • Inhibition of normal and experimental angiotumor endothelial cell proliferation and cell cycle progression by 2-methoxyestradiol
    • Reiser F, Bernas M, Witte M, Witte C. Inhibition of normal and experimental angiotumor endothelial cell proliferation and cell cycle progression by 2-methoxyestradiol. Proc Soc Exp Biol Med. 1998;219:211-216.
    • (1998) Proc Soc Exp Biol Med , vol.219 , pp. 211-216
    • Reiser, F.1    Bernas, M.2    Witte, M.3    Witte, C.4
  • 7
    • 0032994838 scopus 로고    scopus 로고
    • Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines
    • Schumacher G, Kataoka M, Roth JA, Mukhopadhyay T. Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines. Clin Cancer Res. 1999;5:493-499.
    • (1999) Clin Cancer Res , vol.5 , pp. 493-499
    • Schumacher, G.1    Kataoka, M.2    Roth, J.A.3    Mukhopadhyay, T.4
  • 9
    • 17944382346 scopus 로고    scopus 로고
    • Antiangiogenic therapy and radioimmuno-therapy in colon cancer xenografts
    • Kinuya S, Kawashima A, Yokoyama K, et al. Antiangiogenic therapy and radioimmuno-therapy in colon cancer xenografts. Eur J Nucl Med. 2001;28:1306-1312.
    • (2001) Eur J Nucl Med , vol.28 , pp. 1306-1312
    • Kinuya, S.1    Kawashima, A.2    Yokoyama, K.3
  • 10
    • 0034699513 scopus 로고    scopus 로고
    • Superoxide dismutase as a target for the selective killing of cancer cells
    • Huang P, Feng L, Hileman EO, Keating MJ, Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature. 2000;407:390-395.
    • (2000) Nature , vol.407 , pp. 390-395
    • Huang, P.1    Feng, L.2    Hileman, E.O.3    Keating, M.J.4    Plunkett, W.5
  • 11
    • 0030949341 scopus 로고    scopus 로고
    • 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: Possible role for stress-activated protein kinase signaling pathway and Fas expression
    • Yue TL, Wang X, Louden CS, et al. 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: possible role for stress-activated protein kinase signaling pathway and Fas expression. Mol Pharmacol. 1997;51:951-962.
    • (1997) Mol Pharmacol , vol.51 , pp. 951-962
    • Yue, T.L.1    Wang, X.2    Louden, C.S.3
  • 12
    • 0033863030 scopus 로고    scopus 로고
    • 2-Methoxy-estradiol blocks estrogen-induced rat pituitary tumor growth and tumor angiogenesis: Possible role of vascular endothelial growth factor
    • Banerjeei SK, Zoubine MN, Sarkar DK, Weston AP, Shah JH, Campbell DR. 2-Methoxy-estradiol blocks estrogen-induced rat pituitary tumor growth and tumor angiogenesis: possible role of vascular endothelial growth factor. Anticancer Res. 2000;20:2641-2645.
    • (2000) Anticancer Res , vol.20 , pp. 2641-2645
    • Banerjeei, S.K.1    Zoubine, M.N.2    Sarkar, D.K.3    Weston, A.P.4    Shah, J.H.5    Campbell, D.R.6
  • 13
    • 0029008622 scopus 로고
    • Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site
    • Cushman M, He HM, Katzenellenbogen JA, Lin CM, Hamel E. Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site. J Med Chem. 1995;38:2041-2049.
    • (1995) J Med Chem , vol.38 , pp. 2041-2049
    • Cushman, M.1    He, H.M.2    Katzenellenbogen, J.A.3    Lin, C.M.4    Hamel, E.5
  • 15
    • 0031015504 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol
    • Klauber N, Parangi S, Flynn E, Hamel E, D'Amato RJ. Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Res. 1997;57:81-86.
    • (1997) Cancer Res , vol.57 , pp. 81-86
    • Klauber, N.1    Parangi, S.2    Flynn, E.3    Hamel, E.4    D'Amato, R.J.5
  • 17
    • 0034820420 scopus 로고    scopus 로고
    • 2-Methoxymethylestradiol: A new 2-methoxy estrogen analog that exhibits antiproliferative activity and alters tubulin dynamics
    • Brueggemeier RW, Bhat AS, Lovely CJ, et al. 2-Methoxymethylestradiol: a new 2-methoxy estrogen analog that exhibits antiproliferative activity and alters tubulin dynamics. J Steroid Biochem Mol Biol. 2001;78:145-156.
    • (2001) J Steroid Biochem Mol Biol , vol.78 , pp. 145-156
    • Brueggemeier, R.W.1    Bhat, A.S.2    Lovely, C.J.3
  • 18
    • 0034885197 scopus 로고    scopus 로고
    • 2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells
    • Kumar AP, Garcia GE, Slaga TJ. 2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells. Mol Carcinog. 2001;31:111-124.
    • (2001) Mol Carcinog , vol.31 , pp. 111-124
    • Kumar, A.P.1    Garcia, G.E.2    Slaga, T.J.3
  • 19
    • 0035423951 scopus 로고    scopus 로고
    • 2-Methoxyestradiol-induced caspase-3 activation and apoptosis occurs through G(2)/M arrest dependent and independent pathways in gastric carcinoma cells
    • Lin HL, Liu TY, Wu CW, Chi CW. 2-Methoxyestradiol-induced caspase-3 activation and apoptosis occurs through G(2)/M arrest dependent and independent pathways in gastric carcinoma cells. Cancer. 2001;92:500-509.
    • (2001) Cancer , vol.92 , pp. 500-509
    • Lin, H.L.1    Liu, T.Y.2    Wu, C.W.3    Chi, C.W.4
  • 20
    • 0034812089 scopus 로고    scopus 로고
    • 2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer
    • Qadan LR, Perez-Stable CM, Anderson C, et al. 2-Methoxyestradiol induces G2/M arrest and apoptosis in prostate cancer. Biochem Biophys Res Commun. 2001;285:1259-1266.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 1259-1266
    • Qadan, L.R.1    Perez-Stable, C.M.2    Anderson, C.3
  • 21
    • 0034993154 scopus 로고    scopus 로고
    • The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors
    • Schumacher G, Neuhaus P. The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors. J Cancer Res Clin Oncol. 2001;127:405-410.
    • (2001) J Cancer Res Clin Oncol , vol.127 , pp. 405-410
    • Schumacher, G.1    Neuhaus, P.2
  • 22
    • 0030787134 scopus 로고    scopus 로고
    • The mammalian metabolite, 2-methoxyestradiol, affects p53 levels and apoptosis induction in transformed cells but not in normal cells
    • Seegers JC, Lottering M, Grobler CJS, et al. The mammalian metabolite, 2-methoxyestradiol, affects p53 levels and apoptosis induction in transformed cells but not in normal cells. J Steroid Biochem Mol Biol. 1997;62;253-267.
    • (1997) J Steroid Biochem Mol Biol , vol.62 , pp. 253-267
    • Seegers, J.C.1    Lottering, M.2    Grobler, C.J.S.3
  • 23
    • 0031037067 scopus 로고    scopus 로고
    • Induction of apoptosis in human lung cancer cells after wild-type p53 activation by methoxyestradiol
    • Mukhopadhyay T, Roth JA. Induction of apoptosis in human lung cancer cells after wild-type p53 activation by methoxyestradiol. Oncogene. 1997;14:379-384.
    • (1997) Oncogene , vol.14 , pp. 379-384
    • Mukhopadhyay, T.1    Roth, J.A.2
  • 24
    • 0032537850 scopus 로고    scopus 로고
    • Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis
    • Mukhopadhyay T, Roth JA. Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis. Oncogene. 1998;17:241-246.
    • (1998) Oncogene , vol.17 , pp. 241-246
    • Mukhopadhyay, T.1    Roth, J.A.2
  • 25
    • 0032211342 scopus 로고    scopus 로고
    • An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo
    • Kataoka M, Schumacher G, Cristiano RJ, Atkinson EN, Roth JA, Mukhopadhyay T. An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo. Cancer Res. 1998;58:4761-4765.
    • (1998) Cancer Res , vol.58 , pp. 4761-4765
    • Kataoka, M.1    Schumacher, G.2    Cristiano, R.J.3    Atkinson, E.N.4    Roth, J.A.5    Mukhopadhyay, T.6
  • 27
    • 0034885197 scopus 로고    scopus 로고
    • 2-methoxyestradiol blocks cell-cycle progression at G2/M phase and inhibits growth of human prostate cancer cells
    • Kumar AP, Garcia GE, Slaga TJ. 2-methoxyestradiol blocks cell-cycle progression at G2/M phase and inhibits growth of human prostate cancer cells. Mol Carcinog. 2001;31:111-124.
    • (2001) Mol Carcinog , vol.31 , pp. 111-124
    • Kumar, A.P.1    Garcia, G.E.2    Slaga, T.J.3
  • 28
    • 0036173883 scopus 로고    scopus 로고
    • 2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells
    • Maran A, Zhang M, Kennedy AM, et al. 2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells. Bone. 2002;30:393-398.
    • (2002) Bone , vol.30 , pp. 393-398
    • Maran, A.1    Zhang, M.2    Kennedy, A.M.3
  • 29
    • 18744413903 scopus 로고    scopus 로고
    • Inhibition of superoxide dismutase by 2-methoxyoestradiol analogues and oestrogen derivatives: Structure-activity relationships
    • Wood L, Leese MR, Leblond B, et al. Inhibition of superoxide dismutase by 2-methoxyoestradiol analogues and oestrogen derivatives: structure-activity relationships. Anticancer Drug Des. 2001;16:209-215.
    • (2001) Anticancer Drug Des , vol.16 , pp. 209-215
    • Wood, L.1    Leese, M.R.2    Leblond, B.3
  • 30
    • 0033981389 scopus 로고    scopus 로고
    • Free radicals antioxidant enzymes and lipid peroxidation in different types of leukemias
    • Devi GS, Prasad MH, Saraswathi I, Raghu D, Rao DN, Reddy PP. Free radicals antioxidant enzymes and lipid peroxidation in different types of leukemias. Clin Chim Acta. 2000;293;53-62.
    • (2000) Clin Chim Acta , vol.293 , pp. 53-62
    • Devi, G.S.1    Prasad, M.H.2    Saraswathi, I.3    Raghu, D.4    Rao, D.N.5    Reddy, P.P.6
  • 31
    • 33748518966 scopus 로고    scopus 로고
    • Superoxide dismutase: An emerging chemotherapeutic target
    • Hileman EO, Achanta G, Huang P. Superoxide dismutase: an emerging chemotherapeutic target. Expert Opin Ther Targets. 2001;5:697-710.
    • (2001) Expert Opin Ther Targets , vol.5 , pp. 697-710
    • Hileman, E.O.1    Achanta, G.2    Huang, P.3
  • 32
    • 0031960131 scopus 로고    scopus 로고
    • Mitochondrial DNA sequence variation in human leukemic cells
    • Ivanova R, Lepage V, Loste MN, et al. Mitochondrial DNA sequence variation in human leukemic cells. Int J Cancer. 1998;76:495-498.
    • (1998) Int J Cancer , vol.76 , pp. 495-498
    • Ivanova, R.1    Lepage, V.2    Loste, M.N.3
  • 33
    • 0039250954 scopus 로고    scopus 로고
    • Facile detection of mitochonddal DNA mutations in tumors and bodily fluids
    • Fliss MS, Usadel H, Caballero OL, et al. Facile detection of mitochonddal DNA mutations in tumors and bodily fluids. Science. 2000;287:2017-2019.
    • (2000) Science , vol.287 , pp. 2017-2019
    • Fliss, M.S.1    Usadel, H.2    Caballero, O.L.3
  • 34
    • 0036170578 scopus 로고    scopus 로고
    • Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer
    • Tan DJ, Bai RK, Wong LJ. Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res. 2002;62:972-976.
    • (2002) Cancer Res , vol.62 , pp. 972-976
    • Tan, D.J.1    Bai, R.K.2    Wong, L.J.3
  • 35
    • 0037161969 scopus 로고    scopus 로고
    • Mutations in the mitochondrial DNA D-Loop region occur frequently in adenocarcinoma in Barrett's esophagus
    • Miyazono F, Schneider PM, Metzger R, et al. Mutations in the mitochondrial DNA D-Loop region occur frequently in adenocarcinoma in Barrett's esophagus. Oncogene. 2002;21:3780-3783.
    • (2002) Oncogene , vol.21 , pp. 3780-3783
    • Miyazono, F.1    Schneider, P.M.2    Metzger, R.3
  • 36
    • 0033581893 scopus 로고    scopus 로고
    • Mitochondrial DNA determines the cellular response to cancer therapeutic agents
    • Singh KK, Russell J, Sigala B, Zhang Y, Williams J, Keshav KF. Mitochondrial DNA determines the cellular response to cancer therapeutic agents. Oncogene. 1999;18:6641-6646.
    • (1999) Oncogene , vol.18 , pp. 6641-6646
    • Singh, K.K.1    Russell, J.2    Sigala, B.3    Zhang, Y.4    Williams, J.5    Keshav, K.F.6
  • 37
    • 0029982119 scopus 로고    scopus 로고
    • Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species
    • Wang TS, Kuo CF, Jan KY, Huang H. Arsenite induces apoptosis in chinese hamster ovary cells by generation of reactive oxygen species. J Cell Physiol. 1996;169:256-268.
    • (1996) J Cell Physiol , vol.169 , pp. 256-268
    • Wang, T.S.1    Kuo, C.F.2    Jan, K.Y.3    Huang, H.4
  • 38
    • 0031657760 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
    • Chen Y-C, Lin-Shiau S-Y, Lin J-K. Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis. J Cell Physiol. 1998;177:324-333.
    • (1998) J Cell Physiol , vol.177 , pp. 324-333
    • Chen, Y.-C.1    Lin-Shiau, S.-Y.2    Lin, J.-K.3
  • 40
    • 0010740572 scopus 로고    scopus 로고
    • 4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/PML proteins
    • 4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/PML proteins. Blood. 1996;88:1052-1061.
    • (1996) Blood , vol.88 , pp. 1052-1061
    • Chen, G.Q.1    Zhu, J.2    Shi, X.G.3
  • 41
    • 0030610687 scopus 로고    scopus 로고
    • Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL). II. Clinical efficacy and pharmacokinetics in relapsed patients
    • Shen ZX, Chen GQ, Ni JH, et al. Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL). II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood. 1997;89:3354-3360.
    • (1997) Blood , vol.89 , pp. 3354-3360
    • Shen, Z.X.1    Chen, G.Q.2    Ni, J.H.3
  • 42
    • 0000531696 scopus 로고    scopus 로고
    • Arsenic trioxide as an inducer of apoptosis and loss of PML/RARα protein in acute promyelocytic leukemia cells
    • Shao W, Fanelli M, Ferrara FF, et al. Arsenic trioxide as an inducer of apoptosis and loss of PML/RARα protein in acute promyelocytic leukemia cells. J Natl Cancer Inst. 1998;90:124-133.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 124-133
    • Shao, W.1    Fanelli, M.2    Ferrara, F.F.3
  • 43
    • 0033570955 scopus 로고    scopus 로고
    • Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: Remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients
    • Niu C, Yan H, Yu T, et al. Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients. Blood. 1999;94:3315-3324.
    • (1999) Blood , vol.94 , pp. 3315-3324
    • Niu, C.1    Yan, H.2    Yu, T.3
  • 44
    • 0036220360 scopus 로고    scopus 로고
    • Molecular targets of arsenic trioxide in malignant cells
    • Miller WH Jr. Molecular targets of arsenic trioxide in malignant cells. Oncologist. 2002;7(suppl 1):14-19.
    • (2002) Oncologist , vol.7 , Issue.SUPPL. 1 , pp. 14-19
    • Miller W.H., Jr.1
  • 45
    • 0033902940 scopus 로고    scopus 로고
    • Inhibition of RNA transcription: A biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine
    • Huang P, Sandoval A, Van Den NE, Keating MJ, Plunkett W. Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine. Leukemia. 2000;14:1405-1413.
    • (2000) Leukemia , vol.14 , pp. 1405-1413
    • Huang, P.1    Sandoval, A.2    Van Den, N.E.3    Keating, M.J.4    Plunkett, W.5
  • 46
    • 0036140950 scopus 로고    scopus 로고
    • Action of (E)-2′-deoxy-2′-(fluoromethylene) cytidine on DNA metabolism: Incorporation, excision, and cellular response
    • Zhou Y, Achanta G, Pelicano H, Gandhi V, Plunkett W, Huang P. Action of (E)-2′-deoxy-2′-(fluoromethylene) cytidine on DNA metabolism: incorporation, excision, and cellular response. Mol Pharmacol. 2001;61:222-229.
    • (2001) Mol Pharmacol , vol.61 , pp. 222-229
    • Zhou, Y.1    Achanta, G.2    Pelicano, H.3    Gandhi, V.4    Plunkett, W.5    Huang, P.6
  • 47
    • 0033135367 scopus 로고    scopus 로고
    • Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice
    • Fujimura M, Morita-Fujimura Y, Kawase M, et al. Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci. 1999;19:3414-3422.
    • (1999) J Neurosci , vol.19 , pp. 3414-3422
    • Fujimura, M.1    Morita-Fujimura, Y.2    Kawase, M.3
  • 48
    • 0035957592 scopus 로고    scopus 로고
    • Ceramide reduces endothelium-dependent vasodilation by increasing superoxide production in small bovine coronary arteries
    • Zhang DX, Zou AP, Li PL. Ceramide reduces endothelium-dependent vasodilation by increasing superoxide production in small bovine coronary arteries. Circ Res. 2001;88:824-831.
    • (2001) Circ Res , vol.88 , pp. 824-831
    • Zhang, D.X.1    Zou, A.P.2    Li, P.L.3
  • 49
    • 0027764260 scopus 로고
    • Apoptotic cell death in chronic lymphocytic leukemia
    • Robertson LE, Plunkett W. Apoptotic cell death in chronic lymphocytic leukemia. Leuk Lymphoma. 1993;11(suppl 2):71-74.
    • (1993) Leuk Lymphoma , vol.11 , Issue.SUPPL. 2 , pp. 71-74
    • Robertson, L.E.1    Plunkett, W.2
  • 50
    • 0027505303 scopus 로고
    • Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine
    • Robertson LE, Chubb S, Meyn RE, et al. Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine. Blood. 1993;81:143-150.
    • (1993) Blood , vol.81 , pp. 143-150
    • Robertson, L.E.1    Chubb, S.2    Meyn, R.E.3
  • 52
    • 0026879664 scopus 로고
    • An analysis of the role of coenzyme Q in free radical generation and as an oxidant
    • Beyer R. An analysis of the role of coenzyme Q in free radical generation and as an oxidant. Biochem Cell Biol. 1991;70:390-343.
    • (1991) Biochem Cell Biol , vol.70 , pp. 390-343
    • Beyer, R.1
  • 53
    • 0002361650 scopus 로고    scopus 로고
    • Mitochondrial production of superoxide radical and hydrogen peroxide
    • Reivich M, Coburn R, Lahiri S, Chance B, eds. New York: Plenum Press
    • Boveris A, Chance B. Mitochondrial production of superoxide radical and hydrogen peroxide. In: Reivich M, Coburn R, Lahiri S, Chance B, eds. Tissue Hypoxia and Ischemia. New York: Plenum Press; 1997:67-82.
    • (1997) Tissue Hypoxia and Ischemia , pp. 67-82
    • Boveris, A.1    Chance, B.2
  • 54
    • 18344405929 scopus 로고    scopus 로고
    • Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation in vitro
    • Du G, Mouithys-Mickalad A, Sluse-Goffart CM, Droy-Lefaix MT, Sluse FE. Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation in vitro. Free Radic Biol Med. 1998;25:1066-1074.
    • (1998) Free Radic Biol Med , vol.25 , pp. 1066-1074
    • Du, G.1    Mouithys-Mickalad, A.2    Sluse-Goffart, C.M.3    Droy-Lefaix, M.T.4    Sluse, F.E.5
  • 55
    • 0033520921 scopus 로고    scopus 로고
    • Evidence against the generation of free hydroxyl radicals from the interaction of copper, zinc superoxide dismutase and hydrogen peroxide
    • Sankarapandi S, Zweier JL. Evidence against the generation of free hydroxyl radicals from the interaction of copper, zinc superoxide dismutase and hydrogen peroxide. J Biol Chem. 1999;274:34576-34583.
    • (1999) J Biol Chem , vol.274 , pp. 34576-34583
    • Sankarapandi, S.1    Zweier, J.L.2
  • 56
    • 0032422402 scopus 로고    scopus 로고
    • Redox regulation of the caspases during apoptosis
    • Hampton MB, Fadeel B, Orrenius S. Redox regulation of the caspases during apoptosis. Ann N Y Acad Sci. 1998;854:328-335.
    • (1998) Ann N Y Acad Sci , vol.854 , pp. 328-335
    • Hampton, M.B.1    Fadeel, B.2    Orrenius, S.3
  • 58
    • 0036554502 scopus 로고    scopus 로고
    • Mitochondrial superoxide radical formation is controlled by electron bifurcation to the high and low potential pathways
    • Staniek K, Gille L, Kozlov AV, Nohl H. Mitochondrial superoxide radical formation is controlled by electron bifurcation to the high and low potential pathways. Free Radic Res. 2002;36:381-387.
    • (2002) Free Radic Res , vol.36 , pp. 381-387
    • Staniek, K.1    Gille, L.2    Kozlov, A.V.3    Nohl, H.4
  • 59
    • 0024495782 scopus 로고
    • Gene deletion, a mechanism of induced mutation by arabinosyl nucleosides
    • Huang P, Siciliano MJ, Plunkett W. Gene deletion, a mechanism of induced mutation by arabinosyl nucleosides. Mutation Res. 1989;210:291-301.
    • (1989) Mutation Res , vol.210 , pp. 291-301
    • Huang, P.1    Siciliano, M.J.2    Plunkett, W.3
  • 60
    • 0030591653 scopus 로고    scopus 로고
    • Mutagenic damage to mammalian cells by therapeutic alkylating agents
    • 996
    • Sanderson BJ, Shield AJ. Mutagenic damage to mammalian cells by therapeutic alkylating agents. Mutat Res. 996;355:41-57.
    • Mutat Res , vol.355 , pp. 41-57
    • Sanderson, B.J.1    Shield, A.J.2
  • 61
    • 0033568238 scopus 로고    scopus 로고
    • Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway
    • Jing Y, Dai J, Chalmers-Redman RME, Tatton WG, Waxman S. Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway. Blood. 1999;94:2102-2111.
    • (1999) Blood , vol.94 , pp. 2102-2111
    • Jing, Y.1    Dai, J.2    Chalmers-Redman, R.M.E.3    Tatton, W.G.4    Waxman, S.5


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