Specific inhibition of Stat3 signal transduction by PIAS3

Science

Volumn 278, Issue 5344, 1997, Pages 1803-1805

  Chung, Chan D ^a   Liao, Jiayu ^a   Liu, Bin ^b   Rao, Xiaoping ^b   Jay, Philippe ^c   Berta, Philippe ^c   Shuai, Ke ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Centre National de la Recherche Scientifique   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL CELL; DNA BINDING; GENE ACTIVATION; HEPATOMA CELL; HUMAN; HUMAN CELL; MYELOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CELL LINE; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON-ALPHA; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN INHIBITORS OF ACTIVATED STAT; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0030725378     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.278.5344.1803     Document Type: Review

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25. We thank J. Darnell and G. Cheng for plasmids; H. Herschman, O. Witte, and C. Sawyers for reading the manuscript; and A. Dzhragatspanyan for technical assistance. Supported by a predoctoral fellowship from Tumor Cell Surfaces and Chromosomes Training Grant (T32CA09056) (C.D.C.) and by grants from NIH (AI39612) and the Council for Tobacco Research, U.S.A. (4346).