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Volumn 83, Issue 2, 2008, Pages 227-230

The state of innovation in drug development

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; SITAGLIPTIN;

EID: 38349090575     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/sj.clpt.6100479     Document Type: Review
Times cited : (231)

References (11)
  • 1
    • 33947593210 scopus 로고    scopus 로고
    • 2006 drug approvals: Finding the niche
    • Owens, J. 2006 drug approvals: finding the niche. Nat. Rev. Drug Discov. 6, 99-101 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 99-101
    • Owens, J.1
  • 2
    • 0344513886 scopus 로고    scopus 로고
    • Drug development costs about $1.7 billion
    • Mullin, R. Drug development costs about $1.7 billion. Chem. Eng. News 81, 8 (2003).
    • (2003) Chem. Eng. News , vol.81 , pp. 8
    • Mullin, R.1
  • 4
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • Kola, I. & Landis, J. Can the pharmaceutical industry reduce attrition rates? Nat. Rev. Drug Discov. 3, 711-715 (2004).
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 6
    • 27844574358 scopus 로고    scopus 로고
    • Innovation and greater success in drug discovery and development: From targets to biomarkers
    • Kola, I. & Hazuda, D. Innovation and greater success in drug discovery and development: from targets to biomarkers. Curr. Opin. Biotechnol. 16, 644-646 (2005).
    • (2005) Curr. Opin. Biotechnol , vol.16 , pp. 644-646
    • Kola, I.1    Hazuda, D.2
  • 7
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van't Veer, L.J. et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530-536 (2002).
    • (2002) Nature , vol.415 , pp. 530-536
    • van't Veer, L.J.1
  • 8
    • 28444476614 scopus 로고    scopus 로고
    • Pharmacogenetics: Where are we and where are we heading?
    • Kola, I. Pharmacogenetics: where are we and where are we heading? Pharmacogenomics 6, 793-795 (2005).
    • (2005) Pharmacogenomics , vol.6 , pp. 793-795
    • Kola, I.1
  • 10
    • 33749871472 scopus 로고    scopus 로고
    • Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes
    • Herman, G.A. et al. Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes. J. Clin. Endocrinol. Metab. 91, 4612-4619 (2006).
    • (2006) J. Clin. Endocrinol. Metab , vol.91 , pp. 4612-4619
    • Herman, G.A.1
  • 11
    • 33845269380 scopus 로고    scopus 로고
    • The bitterest pill. Nature 444, 532-533 (2006).
    • The bitterest pill. Nature 444, 532-533 (2006).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.