Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts

Molecular Pharmacology

Volumn 69, Issue 4, 2006, Pages 1347-1355

  Chen, Cheng Hsien ^b   Cheng, Tzu Hurng ^b   Lin, Heng ^e   Shih, Neng Lang ^c   Chen, Yen Ling ^e   Chen, Yee Shiuan ^d   Cheng, Ching Feng ^e   Lian, Wei Shiung ^e   Meng, Tzu Ching ^f   Chiu, Wen Ta ^b   Chen, Jin Jer ^a,e  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL UNIVERSITY OF KAOHSIUNG   (Taiwan)

^d UNIVERSITY OF TORONTO   (Canada)

^e INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^f INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ACETYLCYSTEINE; CHLORIDE; DIPHENYLENEIODONIUM CHLORIDE; ENDOTHELIN 1; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; ILOMASTAT; MALACHITE GREEN; PERHYDRO 1 AZEPINYLCARBONYLLEUCYL DEXTRO TRYPTOPHYL DEXTRO TRYPTOPHAN; PROTEIN TYROSINE PHOSPHATASE SHP 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; DRUG EFFECT; DRUG INHIBITION; FIBROBLAST; HEART; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TRANSACTIVATION;

ANIMALS; ENDOTHELIN-1; IMMUNOPRECIPITATION; OXIDATION-REDUCTION; PROTEIN-TYROSINE-PHOSPHATASE; RATS; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TRANS-ACTIVATION (GENETICS);

EID: 33645096801     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.017558     Document Type: Article

References (40)

1. Agazie YM and Hayman MJ (2003) Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling. Mol Cell Biol 23:7875-7886.
2. Ammarguellat F, Larouche I, and Schiffrin EL (2001) Myocardial fibrosis in DOCA-salt hypertensive rats: effect of endothelin ET(A) receptor antagonism. Circulation 103:319-324.
3. Aquilla E, Whelchel A, Knot HJ, Nelson M, and Posada J (1996) Activation of multiple mitogen-activated protein kinase signal transduction pathways by the endothelin B receptor requires the cytoplasmic tail. J Biol Chem 271:31572-31579.
4. Borer JS, Truter S, Herrold EM, Falcone DJ, Pena M, Carter JN, Dumlao TF, Lee JA, and Supino PG (2002) Myocardial fibrosis in chronic aortic regurgitation: molecular and cellular responses to volume overload. Circulation 105:1837-1842.
5. Carpenter G (2000) EGF receptor transactivation mediated by the proteolytic production of EGF-like agonists. Sci STKE 2000:PE1.
6. Cazaubon SM, Ramos-Morales F, Fischer S, Schweighoffer F, Strosberg AD, and Couraud PO (1994) Endothelin induces tyrosine phosphorylation and GRB2 association of Shc in astrocytes. J Biol Chem 269:24805-24809.
7. Cheng CM, Hong HJ, Liu JC, Shih NL, Juan SH, Loh SH, Chan P, Chen JJ, and Cheng TH (2003) Crucial role of extracellular signal-regulated kinase pathway in reactive oxygen species-mediated endothelin-1 gene expression induced by endothelin-1 in rat cardiac fibroblasts. Mol Pharmacol 63:1002-1011.
8. Cheng TH, Shih NL, Chen SY, Wang DL, and Chen JJ (1999) Reactive oxygen species modulate endothelin-I-induced c-fos gene expression in cardiomyocytes. Cardiovasc Res 41:654-662.
9. Chiarugi P and Cirri P (2003) Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction. Trends Biochem Sci 28:509-514.
10. Choi MH, Lee IK, Kim GW, Kim BU, Han YH, Yu DY, Park HS, Kim KY, Lee JS, Choi C, et al. (2005) Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature (Lond) 435:347-353.
11. DeLeo FR and Quinn MT (1996) Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins. J Leukoc Biol 60:677-691.
12. Frank GD, Mifune M, Inagami T, Ohba M, Sasaki T, Higashiyama S, Dempsey PJ, and Eguchi S (2003) Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta. Mol Cell Biol 23:1581-1589.
13. Gschwind A, Zwick E, Prenzel N, Leserer M, and Ullrich A (2001) Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission. Oncogene 20:1594-1600.
14. Herman WH and Simonson MS (1995) Nuclear signaling by endothelin-1. A Ras pathway for activation of the c-fos serum response element. J Biol Chem 270:11654-11661.
15. Hirotani S, Otsu K, Nishida K, Higuchi Y, Morita T, Nakayama H, Yamaguchi O, Mano T, Matsumura Y, Ueno H, et al. (2002) Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation 105:509-515.
16. 2+ signaling via NADPH oxidase and diacylglycerol-sensitive protein kinase C isozymes in mesangial cells. J Biol Chem 278:33951-33962.
17. Kodama H, Fukuda K, Pan J, Makino S, Sano M, Takahashi T, Hori S, and Ogawa S (1998) Biphasic activation of the JAK/STAT pathway by angiotensin II in rat cardiomyocytes. Circ Res 82:244-250.
18. Kodama H, Fukuda K, Takahashi T, Sano M, Kato T, Tahara S, Hakuno D, Sato T, Manabe T, Konishi F, et al. (2002) Role of EGF receptor and Pyk2 in endothelin-1-induced ERK activation in rat cardiomyocytes. J Mol Cell Cardiol 34:139-150.
19. Kovacic B, Ilic D, Damsky CH, and Gardner DG (1998) c-Src activation plays a role in endothelin-dependent hypertrophy of the cardiac myocyte. J Biol Chem 273:35185-35193.
20. Lambeth JD (2004) NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 4:181-189.
21. Lapointe N, Blais C Jr, Adam A, Parker T, Sirois MG, Gosselin H, Clement R, and Rouleau JL (2002) Comparison of the effects of an angiotensin-converting enzyme inhibitor and a vasopeptidase inhibitor after myocardial infarction in the rat. J Am Coll Cardiol 39:1692-1698.
22. Leserer M, Gschwind A, and Ullrich A (2000) Epidermal growth factor receptor signal transactivation. IUBMB Life 49:405-409.
23. Mann DL (1999) Mechanisms and models in heart failure: a combinatorial approach. Circulation 100:999-1008.
24. Markova B, Herrlich P, Ronnstrand L, and Bohmer FD (2003) Identification of protein tyrosine phosphatases associating with the PDGF receptor. Biochemistry 42:2691-2699.
25. Meng TC, Buckley DA, Galic S, Tiganis T, and Tonks NK (2004) Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J Biol Chem 279:37716-37725.
26. Meng TC, Fukada T, and Tonks NK (2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol Cell 9:387-399.
27. Mervaala EM, Cheng ZJ, Tikkanen I, Lapatto R, Nurminen K, Vapaatalo H, Muller DN, Fiebeler A, Ganten U, Ganten D, et al. (2001) Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes. Hypertension 37:414-418.
28. Ostman A and Bohmer FD (2001) Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases. Trends Cell Biol 11:258-266.
29. Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, and Ullrich A (1999) EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature (Lond) 402:884-888.
30. Salmeen A, Andersen JN, Myers MP, Meng TC, Hinks JA, Tonks NK, and Barford D (2003) Redox regulation of protein tyrosine phosphatase 1B involves a sulphenylamide intermediate. Nature (Lond) 423:769-773.
31. Salmeen A and Barford D (2005) Functions and mechanisms of redox regulation of cysteine-based phosphatases. Antioxid Redox Signal 7:560-577.
32. Saxton TM, Henkemeyer M, Gasca S, Shen R, Rossi DJ, Shalaby F, Feng GS, and Pawson T (1997) Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2. EMBO (Eur Mol Biol Organ) J 16:2352-2364.
33. Schieffer B, Bernstein KE, and Marrero MB (1996) The role of tyrosine phosphorylation in angiotensin II mediated intracellular signaling and cell growth. J Mol Med 74:85-91.
34. Smith RM and Curnutte JT (1991) Molecular basis of chronic granulomatous disease. Blood 77:673-686.
35. Stefani M, Caselli A, Bucciantini M, Pazzagli L, Dolfi F, Camici G, Manao G, and Ramponi G (1993) Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes. FEBS Lett 326:131-134.
36. Sugden PH (1999) Signaling in myocardial hypertrophy: life after calcineurin? Circ Res 84:633-646.
37. Thelen M, Dewald B, and Baggiolini M (1993) Neutrophil signal transduction and activation of the respiratory burst. Physiol Rev 73:797-821.
38. Wang Y, Simonson MS, Pouyssegur J, and Dunn MJ (1992) Endothelin rapidly stimulates mitogen-activated protein kinase activity in rat mesangial cells. Biochem J 287:589-594.
39. Xu D, Rovira II, and Finkel T (2002) Oxidants painting the cysteine chapel: redox regulation of PTPs. Dev Cell 2:251-252.
40. Yanagisawa M and Masaki T (1989) Molecular biology and biochemistry of the endothelins. Trends Pharmacol Sci 10:374-378.