Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Oncogene

Volumn 21, Issue 13, 2002, Pages 2000-2008

  Niu, Guilian ^a   Wright, Kenneth L ^a   Huang, Mei ^a   Song, Lanxi ^a   Haura, Eric ^a   Turkson, James ^a   Zhang, Shumin ^a   Wang, Tianhong ^b   Sinibaldi, Dominic ^a   Coppola, Domenico ^a   Heller, Richard ^a   Ellis, Lee M ^c   Karras, James ^d   Bromberg, Jacqueline ^e   Pardoll, Drew ^b   Jove, Richard ^a   Yu, Hua ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d ISIS PHARMACEUTICALS   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Stat3 activation; Tumor angiogenesis; VEGF

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BINDING SITE; CHROMATIN; CONTROLLED STUDY; DOWN REGULATION; GENE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TUMOR;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CELL LINE, TRANSFORMED; COLLAGEN; DNA-BINDING PROTEINS; DOWN-REGULATION; DRUG COMBINATIONS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIAL GROWTH FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LAMININ; LYMPHOKINES; MICE; MUTAGENESIS, SITE-DIRECTED; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; ONCOGENE PROTEIN PP60(V-SRC); PROMOTER REGIONS (GENETICS); PROTEOGLYCANS; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ANIMALIA;

EID: 85047695527     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205260     Document Type: Article

References (49)