-
1
-
-
60149085396
-
The many roles of FAS receptor signaling in the immune system
-
A. Strasser, P. J. Jost, S. Nagata, The many roles of FAS receptor signaling in the immune system. Immunity 30, 180-192 (2009).
-
(2009)
Immunity
, vol.30
, pp. 180-192
-
-
Strasser, A.1
Jost, P.J.2
Nagata, S.3
-
2
-
-
77649152255
-
Autoimmunity and the clearance of dead cells
-
S. Nagata, R. Hanayama, K. Kawane, Autoimmunity and the clearance of dead cells. Cell 140, 619-630 (2010).
-
(2010)
Cell
, vol.140
, pp. 619-630
-
-
Nagata, S.1
Hanayama, R.2
Kawane, K.3
-
3
-
-
41149118513
-
How dying cells alert the immune system to danger
-
H. Kono, K. L. Rock, How dying cells alert the immune system to danger. Nat. Rev. Immunol. 8, 279-289 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
4
-
-
77949847250
-
Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration
-
F. Li, Q. Huang, J. Chen, Y. Peng, D. R. Roop, J. S. Bedford, C. Y. Li, Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration. Sci. Signal. 3, ra13 (2010).
-
(2010)
Sci. Signal.
, vol.3
-
-
Li, F.1
Huang, Q.2
Chen, J.3
Peng, Y.4
Roop, D.R.5
Bedford, J.S.6
Li, C.Y.7
-
5
-
-
69549105422
-
Apoptosis in Drosophila: Compensatory proliferation and undead cells
-
F. A. Martín, A. Peréz-Garijo, G. Morata, Apoptosis in Drosophila: Compensatory proliferation and undead cells. Int. J. Dev. Biol. 53, 1341-1347 (2009).
-
(2009)
Int. J. Dev. Biol.
, vol.53
, pp. 1341-1347
-
-
Martín, F.A.1
Peréz-Garijo, A.2
Morata, G.3
-
6
-
-
78049502859
-
Apoptosis, stem cells, and tissue regeneration
-
A. Bergmann, H. Steller, Apoptosis, stem cells, and tissue regeneration. Sci. Signal. 3, re8 (2010).
-
(2010)
Sci. Signal.
, vol.3
-
-
Bergmann, A.1
Steller, H.2
-
7
-
-
33645965616
-
Reactive oxygen species mediate crosstalk between NF-kB and JNK
-
H. Nakano, A. Nakajima, S. Sakon-Komazawa, J. H. Piao, X. Xue, K. Okumura, Reactive oxygen species mediate crosstalk between NF-kB and JNK. Cell Death Differ. 13, 730-737 (2006).
-
(2006)
Cell Death Differ.
, vol.13
, pp. 730-737
-
-
Nakano, H.1
Nakajima, A.2
Sakon-Komazawa, S.3
Piao, J.H.4
Xue, X.5
Okumura, K.6
-
9
-
-
67649255876
-
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
-
P. Niethammer, C. Grabher, A. T. Look, T. J. Mitchison, A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 459, 996-999 (2009).
-
(2009)
Nature
, vol.459
, pp. 996-999
-
-
Niethammer, P.1
Grabher, C.2
Look, A.T.3
Mitchison, T.J.4
-
10
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
H. Yu, D. Pardoll, R. Jove, STATs in cancer inflammation and immunity: A leading role for STAT3. Nat. Rev. Cancer 9, 798-809 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
11
-
-
19444385692
-
Stat3 regulates genes common to both wound healing and cancer
-
D. J. Dauer, B. Ferraro, L. Song, B. Yu, L. Mora, R. Buettner, S. Enkemann, R. Jove, E. B. Haura, Stat3 regulates genes common to both wound healing and cancer. Oncogene 24, 3397-3408 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 3397-3408
-
-
Dauer, D.J.1
Ferraro, B.2
Song, L.3
Yu, B.4
Mora, L.5
Buettner, R.6
Enkemann, S.7
Jove, R.8
Haura, E.B.9
-
12
-
-
74549217325
-
Hepatocyte IKKβ/NF-κB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation
-
G. He, G. Y. Yu, V. Temkin, H. Ogata, C. Kuntzen, T. Sakurai, W. Sieghart, M. Peck- Radosavljevic, H. L. Leffert, M. Karin, Hepatocyte IKKβ/NF-κB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. Cancer Cell 17, 286-297 (2010).
-
(2010)
Cancer Cell
, vol.17
, pp. 286-297
-
-
He, G.1
Yu, G.Y.2
Temkin, V.3
Ogata, H.4
Kuntzen, C.5
Sakurai, T.6
Sieghart, W.7
Peck-Radosavljevic, M.8
Leffert, H.L.9
Karin, M.10
-
13
-
-
77955992756
-
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
-
D. Iliopoulos, S. A. Jaeger, H. A. Hirsch, M. L. Bulyk, K. Struhl, STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol. Cell 39, 493-506 (2010).
-
(2010)
Mol. Cell
, vol.39
, pp. 493-506
-
-
Iliopoulos, D.1
Jaeger, S.A.2
Hirsch, H.A.3
Bulyk, M.L.4
Struhl, K.5
-
14
-
-
33751558995
-
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway
-
A. Nakajima, S. Komazawa-Sakon, M. Takekawa, T. Sasazuki, W. C. Yeh, H. Yagita, K. Okumura, H. Nakano, An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway. EMBO J. 25, 5549-5559 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 5549-5559
-
-
Nakajima, A.1
Komazawa-Sakon, S.2
Takekawa, M.3
Sasazuki, T.4
Yeh, W.C.5
Yagita, H.6
Okumura, K.7
Nakano, H.8
-
16
-
-
78649744885
-
More than a sidekick: The IL-6 family cytokine IL-11 links inflammation to cancer
-
T. Putoczki, M. Ernst, More than a sidekick: The IL-6 family cytokine IL-11 links inflammation to cancer. J. Leukoc. Biol. 88, 1109-1117 (2010).
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 1109-1117
-
-
Putoczki, T.1
Ernst, M.2
-
17
-
-
0032489432
-
Transforming growth factor-β stimulates interleukin-11 transcription via complex activating protein-1-dependent pathways
-
W. Tang, L. Yang, Y. C. Yang, S. X. Leng, J. A. Elias, Transforming growth factor-β stimulates interleukin-11 transcription via complex activating protein-1-dependent pathways. J. Biol. Chem. 273, 5506-5513 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5506-5513
-
-
Tang, W.1
Yang, L.2
Yang, Y.C.3
Leng, S.X.4
Elias, J.A.5
-
18
-
-
8944252345
-
Interleukin-11 mRNA stabilization in phorbol ester-stimulated primate bone marrow stromal cells
-
L. Yang, C. N. Steussy, D. K. Fuhrer, J. Hamilton, Y. C. Yang, Interleukin-11 mRNA stabilization in phorbol ester-stimulated primate bone marrow stromal cells. Mol. Cell. Biol. 16, 3300-3307 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3300-3307
-
-
Yang, L.1
Steussy, C.N.2
Fuhrer, D.K.3
Hamilton, J.4
Yang, Y.C.5
-
19
-
-
0032899637
-
2+to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes
-
2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes. Hepatology 29, 1523-1531 (1999).
-
(1999)
Hepatology
, vol.29
, pp. 1523-1531
-
-
Byrne, A.M.1
Lemasters, J.J.2
Nieminen, A.L.3
-
20
-
-
0042525938
-
NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
-
S. Sakon, X. Xue, M. Takekawa, T. Sasazuki, T. Okazaki, Y. Kojima, J. H. Piao, H. Yagita, K. Okumura, T. Doi, H. Nakano, NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J. 22, 3898-3909 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 3898-3909
-
-
Sakon, S.1
Xue, X.2
Takekawa, M.3
Sasazuki, T.4
Okazaki, T.5
Kojima, Y.6
Piao, J.H.7
Yagita, H.8
Okumura, K.9
Doi, T.10
Nakano, H.11
-
21
-
-
14844327760
-
Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
H. Kamata, S. Honda, S. Maeda, L. Chang, H. Hirata, M. Karin, Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120, 649-661 (2005).
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
Honda, S.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
22
-
-
33750299450
-
Protein tyrosine phosphatases: From genes, to function, to disease
-
N. K. Tonks, Protein tyrosine phosphatases: From genes, to function, to disease. Nat. Rev. Mol. Cell Biol. 7, 833-846 (2006).
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 833-846
-
-
Tonks, N.K.1
-
24
-
-
0035007341
-
Protective effect of rhIL-11 in a murine model of acetaminophen-induced hepatotoxicity
-
W. L. Trepicchio, M. Bozza, P. Bouchard, A. J. Dorner, Protective effect of rhIL-11 in a murine model of acetaminophen-induced hepatotoxicity. Toxicol. Pathol. 29, 242-249 (2001).
-
(2001)
Toxicol. Pathol.
, vol.29
, pp. 242-249
-
-
Trepicchio, W.L.1
Bozza, M.2
Bouchard, P.3
Dorner, A.J.4
-
25
-
-
79953127652
-
Non-core region modulates interleukin-11 signaling activity: Generation of agonist and antagonist variants
-
S. Yanaka, E. Sano, N. Naruse, K.Miura,M. Futatsumori-Sugai, J. M. Caaveiro, K. Tsumoto, Non-core region modulates interleukin-11 signaling activity: Generation of agonist and antagonist variants. J. Biol. Chem. 286, 8085-8093 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 8085-8093
-
-
Yanaka, S.1
Sano, E.2
Naruse, N.3
Miura, K.4
Futatsumori-Sugai, M.5
Caaveiro, J.M.6
Tsumoto, K.7
-
26
-
-
34547111683
-
Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity
-
T. Kawakami, T. Takahashi, H. Shimizu, K. Nakahira, M. Takeuchi, H. Katayama, M. Yokoyama, K. Morita, R. Akagi, S. Sassa, Highly liver-specific heme oxygenase-1 induction by interleukin-11 prevents carbon tetrachloride-induced hepatotoxicity. Int. J. Mol. Med. 18, 537-546 (2006).
-
(2006)
Int. J. Mol. Med.
, vol.18
, pp. 537-546
-
-
Kawakami, T.1
Takahashi, T.2
Shimizu, H.3
Nakahira, K.4
Takeuchi, M.5
Katayama, H.6
Yokoyama, M.7
Morita, K.8
Akagi, R.9
Sassa, S.10
-
27
-
-
0038297467
-
Interleukin- 11-induced heat shock protein 25 confers intestinal epithelial-specific cytoprotection from oxidant stress
-
M. J. Ropeleski, J. Tang, M. M. Walsh-Reitz, M. W. Musch, E. B. Chang, Interleukin- 11-induced heat shock protein 25 confers intestinal epithelial-specific cytoprotection from oxidant stress. Gastroenterology 124, 1358-1368 (2003).
-
(2003)
Gastroenterology
, vol.124
, pp. 1358-1368
-
-
Ropeleski, M.J.1
Tang, J.2
Walsh-Reitz, M.M.3
Musch, M.W.4
Chang, E.B.5
-
28
-
-
0030847329
-
Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis
-
H. H. Nandurkar, L. Robb, D. Tarlinton, L. Barnett, F. Kontgen, C. G. Begley, Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis. Blood 90, 2148-2159 (1997).
-
(1997)
Blood
, vol.90
, pp. 2148-2159
-
-
Nandurkar, H.H.1
Robb, L.2
Tarlinton, D.3
Barnett, L.4
Kontgen, F.5
Begley, C.G.6
-
29
-
-
0031916723
-
Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation
-
L. Robb, R. Li, L. Hartley, H. H. Nandurkar, F. Koentgen, C. G. Begley, Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation. Nat. Med. 4, 303-308 (1998).
-
(1998)
Nat. Med.
, vol.4
, pp. 303-308
-
-
Robb, L.1
Li, R.2
Hartley, L.3
Nandurkar, H.H.4
Koentgen, F.5
Begley, C.G.6
-
30
-
-
43049096401
-
STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice
-
M. Ernst, M. Najdovska, D. Grail, T. Lundgren-May, M. Buchert, H. Tye, V. B. Matthews, J. Armes, P. S. Bhathal, N. R. Hughes, E. G. Marcusson, J. G. Karras, S. Na, J. D. Sedgwick, P. J. Hertzog, B. J. Jenkins, STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. J. Clin. Invest. 118, 1727-1738 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1727-1738
-
-
Ernst, M.1
Najdovska, M.2
Grail, D.3
Lundgren-May, T.4
Buchert, M.5
Tye, H.6
Matthews, V.B.7
Armes, J.8
Bhathal, P.S.9
Hughes, N.R.10
Marcusson, E.G.11
Karras, J.G.12
Na, S.13
Sedgwick, J.D.14
Hertzog, P.J.15
Jenkins, B.J.16
-
31
-
-
60449103529
-
The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development
-
M. Howlett, A. S. Giraud, H. Lescesen, C. B. Jackson, A. Kalantzis, I. R. Van Driel, L. Robb, M. Van der Hoek, M. Ernst, T. Minamoto, A. Boussioutas, H. Oshima, M. Oshima, L. M. Judd, The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development. Gastroenterology 136, 967-977 (2009).
-
(2009)
Gastroenterology
, vol.136
, pp. 967-977
-
-
Howlett, M.1
Giraud, A.S.2
Lescesen, H.3
Jackson, C.B.4
Kalantzis, A.5
Van Driel, I.R.6
Robb, L.7
Van Der Hoek, M.8
Ernst, M.9
Minamoto, T.10
Boussioutas, A.11
Oshima, H.12
Oshima, M.13
Judd, L.M.14
-
32
-
-
34447327216
-
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
-
W. E. Naugler, T. Sakurai, S. Kim, S. Maeda, K. Kim, A. M. Elsharkawy, M. Karin, Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317, 121-124 (2007).
-
(2007)
Science
, vol.317
, pp. 121-124
-
-
Naugler, W.E.1
Sakurai, T.2
Kim, S.3
Maeda, S.4
Kim, K.5
Elsharkawy, A.M.6
Karin, M.7
-
33
-
-
21244472975
-
IKKb couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
S. Maeda, H. Kamata, J. L. Luo, H. Leffert, M. Karin, IKKb couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121, 977-990 (2005).
-
(2005)
Cell
, vol.121
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.L.3
Leffert, H.4
Karin, M.5
-
34
-
-
33846839443
-
Deletion of NEMO/IKKg in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
-
T. Luedde, N. Beraza, V. Kotsikoris, G. van Loo, A. Nenci, R. De Vos, T. Roskams, C. Trautwein, M. Pasparakis, Deletion of NEMO/IKKg in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11, 119-132 (2007).
-
(2007)
Cancer Cell
, vol.11
, pp. 119-132
-
-
Luedde, T.1
Beraza, N.2
Kotsikoris, V.3
Van Loo, G.4
Nenci, A.5
De Vos, R.6
Roskams, T.7
Trautwein, C.8
Pasparakis, M.9
-
35
-
-
58649101347
-
gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
-
J. Bollrath, T. J. Phesse, V. A. von Burstin, T. Putoczki, M. Bennecke, T. Bateman, T. Nebelsiek, T. Lundgren-May, O. Canli, S. Schwitalla, V. Matthews, R. M. Schmid, T. Kirchner, M. C. Arkan, M. Ernst, F. R. Greten, gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 15, 91-102 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 91-102
-
-
Bollrath, J.1
Phesse, T.J.2
Von Burstin, V.A.3
Putoczki, T.4
Bennecke, M.5
Bateman, T.6
Nebelsiek, T.7
Lundgren-May, T.8
Canli, O.9
Schwitalla, S.10
Matthews, V.11
Schmid, R.M.12
Kirchner, T.13
Arkan, M.C.14
Ernst, M.15
Greten, F.R.16
-
36
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
S. Grivennikov, E. Karin, J. Terzic, D. Mucida, G. Y. Yu, S. Vallabhapurapu, J. Scheller, S. Rose-John, H. Cheroutre, L. Eckmann, M. Karin, IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 15, 103-113 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.Y.5
Vallabhapurapu, S.6
Scheller, J.7
Rose-John, S.8
Cheroutre, H.9
Eckmann, L.10
Karin, M.11
-
37
-
-
55549123541
-
Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity
-
T. Sawada, C. Nishiyama, T. Kishi, T. Sasazuki, S. Komazawa-Sakon, X. Xue, J. H. Piao, H. Ogata, J. Nakayama, T. Taki, Y. Hayashi, M. Watanabe, H. Yagita, K. Okumura, H. Nakano, Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity. J. Biol. Chem. 283, 26820-26828 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26820-26828
-
-
Sawada, T.1
Nishiyama, C.2
Kishi, T.3
Sasazuki, T.4
Komazawa-Sakon, S.5
Xue, X.6
Piao, J.H.7
Ogata, H.8
Nakayama, J.9
Taki, T.10
Hayashi, Y.11
Watanabe, M.12
Yagita, H.13
Okumura, K.14
Nakano, H.15
-
38
-
-
33751014863
-
Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: Role of intracellular calcium and nitric oxide
-
D. M. Zheng, T. Kitamura, K. Ikejima, N. Enomoto, S. Yamashina, S. Suzuki, Y. Takei, N. Sato, Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: Role of intracellular calcium and nitric oxide. Hepatology 44, 1278-1287 (2006).
-
(2006)
Hepatology
, vol.44
, pp. 1278-1287
-
-
Zheng, D.M.1
Kitamura, T.2
Ikejima, K.3
Enomoto, N.4
Yamashina, S.5
Suzuki, S.6
Takei, Y.7
Sato, N.8
-
39
-
-
0022416353
-
Preparation of pure hepatocytes and reticuloendothelial cells in high yield from a single rat liver by means of Percoll centrifugation and selective adherence
-
B. Smedsrød, H. Pertoft, Preparation of pure hepatocytes and reticuloendothelial cells in high yield from a single rat liver by means of Percoll centrifugation and selective adherence. J. Leukoc. Biol. 38, 213-230 (1985).
-
(1985)
J. Leukoc. Biol.
, vol.38
, pp. 213-230
-
-
Smedsrød, B.1
Pertoft, H.2
-
40
-
-
19044398777
-
Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death
-
T. Sasazuki, T. Sawada, S. Sakon, T. Kitamura, T. Kishi, T. Okazaki, M. Katano, M. Tanaka, M. Watanabe, H. Yagita, K. Okumura, H. Nakano, Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death. J. Biol. Chem. 277, 28853-28860 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28853-28860
-
-
Sasazuki, T.1
Sawada, T.2
Sakon, S.3
Kitamura, T.4
Kishi, T.5
Okazaki, T.6
Katano, M.7
Tanaka, M.8
Watanabe, M.9
Yagita, H.10
Okumura, K.11
Nakano, H.12
|