Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload

Circulation

Volumn 122, Issue 4, 2010, Pages 361-369

  Fu, Hai Ying ^a   Okada, Ken Ichiro ^a   Liao, Yulin ^d   Tsukamoto, Osamu ^a   Isomura, Tadashi ^b   Asai, Mitsutoshi ^a   Sawada, Tamaki ^a   Okuda, Keiji ^a   Asano, Yoshihiro ^a   Sanada, Shoji ^c   Asanuma, Hiroshi ^c   Asakura, Masanori ^c   Takashima, Seiji ^a   Komuro, Issei ^a   Kitakaze, Masafumi ^c   Minamino, Tetsuo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Hayama Heart Center   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; endoplasmic reticulum; heart failure; hypertrophy

Indexed keywords

C EBP HOMOLOGOUS PROTEIN; CASPASE 3; CCAAT ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; AORTA CONSTRICTION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HEART FAILURE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SHAM PROCEDURE; WILD TYPE;

ANIMALS; APOPTOSIS; CARDIOMYOPATHIES; CCAAT-ENHANCER-BINDING PROTEINS; DNA PRIMERS; HEART FAILURE; HUMANS; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCYTES, CARDIAC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STROKE VOLUME;

EID: 77955173081     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.109.917914     Document Type: Article

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