-
1
-
-
82955247909
-
IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
-
David RW, Guariguata L, Weil C, Shaw J. IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res Clin Pract 2011; 94: 311-21.
-
(2011)
Diabetes Res Clin Pract
, vol.94
, pp. 311-321
-
-
David, R.W.1
Guariguata, L.2
Weil, C.3
Shaw, J.4
-
2
-
-
0035856980
-
Biology of diabetic complications
-
Brownlee M. Biology of diabetic complications. Nature 2001; 414: 813-20.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
3
-
-
34249328873
-
Biomarkers of susceptibility to type 1 diabetes with special reference to the Indian population
-
Mehra NK, Kumar N, Kaur G, Kanga U, Tandon N. Biomarkers of susceptibility to type 1 diabetes with special reference to the Indian population. Indian J Med Res 2007; 321-44.
-
(2007)
Indian J Med Res
, pp. 321-344
-
-
Mehra, N.K.1
Kumar, N.2
Kaur, G.3
Kanga, U.4
Tandon, N.5
-
4
-
-
79551640972
-
Preventing type 2 diabetes mellitus: Room for residual risk reduction after lifestyle changes?
-
Athyros VG, Tziomalos K, Karagiannis A, Mikhailidis DP. Preventing type 2 diabetes mellitus: room for residual risk reduction after lifestyle changes? Curr Pharm Des 2010; 16(34): 3939-47.
-
(2010)
Curr Pharm Des
, vol.16
, Issue.34
, pp. 3939-3947
-
-
Athyros, V.G.1
Tziomalos, K.2
Karagiannis, A.3
Mikhailidis, D.P.4
-
5
-
-
0037283601
-
The relative contributions of insulin resistance and betacell dysfunction to the pathophysiology of type 2 diabetes
-
Kahan SE. The relative contributions of insulin resistance and betacell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003; 46: 3-19.
-
(2003)
Diabetologia
, vol.46
, pp. 3-19
-
-
Kahan, S.E.1
-
6
-
-
79953763364
-
Signaling of reactive oxygen and nitrogen species in diabetes mellitus
-
Afanas'ev I. Signaling of reactive oxygen and nitrogen species in diabetes mellitus. Oxid Med Cell Longev 2010; 3(6): 361-73.
-
(2010)
Oxid Med Cell Longev
, vol.3
, Issue.6
, pp. 361-373
-
-
Afanas'ev, I.1
-
7
-
-
34347352169
-
Diabetic cardiomyopathy revisited
-
Boudina S. Abel ED. Diabetic cardiomyopathy revisited. Circulation 2007; 115: 3213-23.
-
(2007)
Circulation
, vol.115
, pp. 3213-3223
-
-
Boudina, S.1
Abel, E.D.2
-
8
-
-
30044435707
-
Early detection of diabetic cardiomyopathy: Usefulness of tissue Doppler imaging
-
Di Bonito P, Moio N, Cavuto L, et al. Early detection of diabetic cardiomyopathy: usefulness of tissue Doppler imaging. Diabet Med 2005; 22: 1720-25
-
(2005)
Diabet Med
, vol.22
, pp. 1720-1725
-
-
Di Bonito, P.1
Moio, N.2
Cavuto, L.3
-
9
-
-
37849047917
-
Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options
-
Witteles RM, Fowler MB. Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options. J Am Coll Cardiol 2008; 51(2): 27-9.
-
(2008)
J Am Coll Cardiol
, vol.51
, Issue.2
, pp. 27-29
-
-
Witteles, R.M.1
Fowler, M.B.2
-
10
-
-
33846826589
-
Post-translational protein modifications in type 1 diabetes: Role for the repair enzyme protein-L-isoaspartate (D-aspartate) O-methyltransferase?
-
Wägner AM, Cloos P, Bergholdt R, et al. Post-translational protein modifications in type 1 diabetes: role for the repair enzyme protein-L-isoaspartate (D-aspartate) O-methyltransferase? Diabetologia 2007; 50(3): 676-81.
-
(2007)
Diabetologia
, vol.50
, Issue.3
, pp. 676-681
-
-
Wägner, A.M.1
Cloos, P.2
Bergholdt, R.3
-
12
-
-
84865299042
-
Protein acetylation mechanisms in the regulation of insulin and insulin-like growth factor 1 signalling
-
Pirola L, Zerzaihi O, Vidal H, Solari F. Protein acetylation mechanisms in the regulation of insulin and insulin-like growth factor 1 signalling. Mol Cell Endocrinol.2012; 1-10.
-
(2012)
Mol Cell Endocrinol
, pp. 1-10
-
-
Pirola, L.1
Zerzaihi, O.2
Vidal, H.3
Solari, F.4
-
13
-
-
77955707062
-
Potential role of sirtuin as a therapeutic target for neurodegenerative diseases
-
Han SH. Potential role of sirtuin as a therapeutic target for neurodegenerative diseases. J Clin Neurol 2009; 5(3): 120-5.
-
(2009)
J Clin Neurol
, vol.5
, Issue.3
, pp. 120-125
-
-
Han, S.H.1
-
15
-
-
70350441907
-
The role of sirtuins in the control of metabolic homeostasis
-
Yu J, Auwerx J. The role of sirtuins in the control of metabolic homeostasis. Ann N Y Acad Sci 2009; 19: 10-9.
-
(2009)
Ann N Y Acad Sci
, vol.19
, pp. 10-19
-
-
Yu, J.1
Auwerx, J.2
-
17
-
-
26244436281
-
Evolutionarily conserved and non-conserved cellular localizations and functions of human SIRT proteins
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I. Evolutionarily conserved and non-conserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 2005; 16: 4623-35.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
18
-
-
34548150187
-
The role of nuclear architecture in genomic instability and ageing
-
Oberdoerffer P, Sinclair DA. The role of nuclear architecture in genomic instability and ageing. Nat Rev Mol Cell Biol 2007; 8: 692-702.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 692-702
-
-
Oberdoerffer, P.1
Sinclair, D.A.2
-
21
-
-
33751113602
-
Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction
-
Haigis MC, Guarente LP. Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes Dev 2006; 20(21): 2913-21.
-
(2006)
Genes Dev
, vol.20
, Issue.21
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
22
-
-
84859977895
-
Sirtuins mediate mammalian metabolic responses to nutrient availability
-
Chalkiadaki A, Guarente L. Sirtuins mediate mammalian metabolic responses to nutrient availability. Nat Rev Endocrinol 2012; 8(5): 287-96.
-
(2012)
Nat Rev Endocrinol
, vol.8
, Issue.5
, pp. 287-296
-
-
Chalkiadaki, A.1
Guarente, L.2
-
24
-
-
77951217683
-
SIRT1 regulates auto acetylation and histone acetyltransferase activity of TIP60
-
Wang J, Chen J. SIRT1 regulates auto acetylation and histone acetyltransferase activity of TIP60. J Bio Chem 2010; 285 (15): 11458-11464.
-
(2010)
J Bio Chem
, vol.285
, Issue.15
, pp. 11458-11464
-
-
Wang, J.1
Chen, J.2
-
25
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
Langley E, Pearson M, Faretta M, et al. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO 2002; 21 (10): 2383-96.
-
(2002)
EMBO
, vol.21
, Issue.10
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
-
26
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo 1-mediated transcription through its deacetylase activity
-
Daitoku H, Hatta M, Matsuzaki H, et al. Silent information regulator 2 potentiates Foxo 1-mediated transcription through its deacetylase activity. Proc Natl Acad Sci 2004; 101(27): 10042-7.
-
(2004)
Proc Natl Acad Sci
, vol.101
, Issue.27
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
-
27
-
-
16344384026
-
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
-
Yang Y, Hou H, Haller EM, Nicosia SV, Bai W. Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. EMBO 2005; 24(5): 1021-32.
-
(2005)
EMBO
, vol.24
, Issue.5
, pp. 1021-1032
-
-
Yang, Y.1
Hou, H.2
Haller, E.M.3
Nicosia, S.V.4
Bai, W.5
-
28
-
-
70349633646
-
TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SIRT1
-
Cardellini M, Menghini R, Martelli E, et al. TIMP3 Is Reduced in Atherosclerotic Plaques From Subjects With Type 2 Diabetes and Increased by SIRT1. Diabetes 2009; 58(10): 2396-401.
-
(2009)
Diabetes
, vol.58
, Issue.10
, pp. 2396-2401
-
-
Cardellini, M.1
Menghini, R.2
Martelli, E.3
-
29
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta MC, Divecha N, Lemieux M, et al. Mammalian SIRT1 represses forkhead transcription factors. Cell 2004; 116(4): 551-63.
-
(2004)
Cell
, vol.116
, Issue.4
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
-
30
-
-
0035913911
-
Negative control of p53 by Sir2α promotes cell survival under stress
-
Luo J, Nikolaev AY, Imai SI, et al. Negative control of p53 by Sir2α promotes cell survival under stress. Cell 2001; 107(2): 137-48.
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.I.3
-
31
-
-
3142548829
-
Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10
-
Bae NS, Swanson MJ, Vassilev A, Howard BH. Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10. J Bio 2004; 135(6): 695-700.
-
(2004)
J Bio
, vol.135
, Issue.6
, pp. 695-700
-
-
Bae, N.S.1
Swanson, M.J.2
Vassilev, A.3
Howard, B.H.4
-
32
-
-
33745889628
-
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
-
Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E. Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci 2006; 103(27): 10224-9.
-
(2006)
Proc Natl Acad Sci
, vol.103
, Issue.27
, pp. 10224-10229
-
-
Schwer, B.1
Bunkenborg, J.2
Verdin, R.O.3
Andersen, J.S.4
Verdin, E.5
-
33
-
-
79952117379
-
Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats
-
Chen YR, Fang SR, Fu YC, Zhou XH, Xu MY, Xu WC. Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats. Biochem Cell Biol 2010; 88(4): 715-22.
-
(2010)
Biochem Cell Biol
, vol.88
, Issue.4
, pp. 715-722
-
-
Chen, Y.R.1
Fang, S.R.2
Fu, Y.C.3
Zhou, X.H.4
Xu, M.Y.5
Xu, W.C.6
-
34
-
-
10044262126
-
The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60
-
Patel JH, Du Y, Ard PG, et al. The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. Mol Cell Bio 2004; 24: 10826-34.
-
(2004)
Mol Cell Bio
, vol.24
, pp. 10826-10834
-
-
Patel, J.H.1
Du, Y.2
Ard, P.G.3
-
35
-
-
62149130110
-
Cellular regulation of SIRT1
-
Milner J. Cellular regulation of SIRT1. Curr Pharm Des 2009; 15(1): 39-44.
-
(2009)
Curr Pharm Des
, vol.15
, Issue.1
, pp. 39-44
-
-
Milner, J.1
-
36
-
-
80055085693
-
Role of sirtuins and calorie restriction in neuroprotection: Implications in Alzheimer's and Parkinson's diseases
-
Srivastava S, Haigis MC. Role of sirtuins and calorie restriction in neuroprotection: implications in Alzheimer's and Parkinson's diseases. Curr Pharm Des 2011; 17(31): 3418-33.
-
(2011)
Curr Pharm Des
, vol.17
, Issue.31
, pp. 3418-3433
-
-
Srivastava, S.1
Haigis, M.C.2
-
38
-
-
77958523925
-
NAD 1-dependent histone deacetylases (sirtuins) as novel therapeutictargets
-
Uciechowska U, Sippl W, Jung M. NAD 1-dependent histone deacetylases (sirtuins) as novel therapeutictargets. Med Res Rev 2009; 30(6): 861-89.
-
(2009)
Med Res Rev
, vol.30
, Issue.6
, pp. 861-889
-
-
Uciechowska, U.1
Sippl, W.2
Jung, M.3
-
39
-
-
77953240381
-
Sirtuins
-
Lin S. Sirtuins. Biochim Biophys Acta 2010; 1804: 1565-6.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1565-1566
-
-
Lin, S.1
-
40
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell 2003; 11: 437-44.
-
(2003)
Mol. Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
41
-
-
2342496712
-
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
-
Accili D, Arden KC. FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 2004; 117: 421-6.
-
(2004)
Cell
, vol.117
, pp. 421-426
-
-
Accili, D.1
Arden, K.C.2
-
42
-
-
0036629251
-
Cell cycle and death control: Long live Forkheads
-
Burgering BM, Kops GJ. Cell cycle and death control: long live Forkheads. Trends Biochem Sci 2002; 27: 352-60.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 352-360
-
-
Burgering, B.M.1
Kops, G.J.2
-
43
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer E, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 2005; 24: 7410-25.
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.1
Brunet, A.2
-
44
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 2005; 120: 449-60.
-
(2005)
Cell
, vol.120
, pp. 449-460
-
-
Kenyon, C.1
-
46
-
-
42349085704
-
Sirt1 contributes critically to the redox-dependent fate of neural progenitors
-
Prozorovski T, Topphoff SU, Glumm R, et al. Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat. Cell Biol 2008; 10: 385-94.
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 385-394
-
-
Prozorovski, T.1
Topphoff, S.U.2
Glumm, R.3
-
47
-
-
28644447272
-
The antioxidant functions of the p53 tumor suppressor
-
Sablina AA, Budanov AV, Ilyinskaya GV, et al. The antioxidant functions of the p53 tumor suppressor. Nat. Med 2005; 11: 1306-13.
-
(2005)
Nat. Med
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
-
48
-
-
79961180595
-
p53, oxidative stress and aging
-
Liu D, Xu Y. p53, oxidative stress and aging. Antioxid Redox Signal 2011; 15(6): 1669-78.
-
(2011)
Antioxid Redox Signal
, vol.15
, Issue.6
, pp. 1669-1678
-
-
Liu, D.1
Xu, Y.2
-
49
-
-
39749087530
-
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
-
Han MK, Song EK, Guo Y, Ou X, Mantel C, Broxmeyer HE. SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2008; 2: 241-51.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 241-251
-
-
Han, M.K.1
Song, E.K.2
Guo, Y.3
Ou, X.4
Mantel, C.5
Broxmeyer, H.E.6
-
50
-
-
0035913903
-
hSIR2 (SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H, Dessain SK, Ng EE, et al. hSIR2 (SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001; 107: 149-59.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng, E.E.3
-
51
-
-
77449121720
-
SIRT1 confers protection against UVB and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes
-
Cao C, Lu S, Kivlin R, Wallin B, Card E, Bagdasarian A, et al. SIRT1 confers protection against UVB and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes. J Cell Mol Med 2009; 13(9B): 3632-43.
-
(2009)
J Cell Mol Med
, vol.13
, Issue.9 B
, pp. 3632-3643
-
-
Cao, C.1
Lu, S.2
Kivlin, R.3
Wallin, B.4
Card, E.5
Bagdasarian, A.6
-
52
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu YS, Patel P, et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc. Natl. Acad. Sci 2003; 100(19): 10794-9.
-
(2003)
Proc. Natl. Acad. Sci
, vol.100
, Issue.19
, pp. 10794-10799
-
-
Cheng, H.L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.S.5
Patel, P.6
-
53
-
-
33745166337
-
Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation
-
Kume S, Haneda M, Kanasaki K. et al. Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation. Free Radic. Biol. Med 2006; 40: 2175-82.
-
(2006)
Free Radic. Biol. Med
, vol.40
, pp. 2175-2182
-
-
Kume, S.1
Haneda, M.2
Kanasaki, K.3
-
54
-
-
33748200050
-
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage
-
Wang C, Chen L, Hou X, et al. Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat Cell Biol 2006; 8(9): 1025-31.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.9
, pp. 1025-1031
-
-
Wang, C.1
Chen, L.2
Hou, X.3
-
55
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004; 303: 2011-5.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
-
56
-
-
34447626095
-
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
-
Wang F, Nguyen M, Qin FX, Tong Q. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 2007; 6: 505-14.
-
(2007)
Aging Cell
, vol.6
, pp. 505-514
-
-
Wang, F.1
Nguyen, M.2
Qin, F.X.3
Tong, Q.4
-
57
-
-
66149163230
-
A "FOXO" in sight: Targeting Foxo proteins from conception to cancer
-
Maiese K, Chong ZZ, Shang YC, Hou J. A "FOXO" in sight: targeting Foxo proteins from conception to cancer. Med Res Rev 2009; 29: 395-418.
-
(2009)
Med Res Rev
, vol.29
, pp. 395-418
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
Hou, J.4
-
58
-
-
46349096040
-
Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression
-
Hasegawa K, Wakino S, Yoshioka K, et al. Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression. Biochem Biophys Res Commun 2008; 372: 51-6.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 51-56
-
-
Hasegawa, K.1
Wakino, S.2
Yoshioka, K.3
-
59
-
-
80051534214
-
Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress
-
Hou J, Wang S, Shang YC, et al. Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress. Curr Neurovasc Res 2011; 8: 220-35.
-
(2011)
Curr Neurovasc Res
, vol.8
, pp. 220-235
-
-
Hou, J.1
Wang, S.2
Shang, Y.C.3
-
60
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
Kops GJ, Dansen TB, Polderman PE, et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 2002; 419: 316-21.
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
-
61
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
Alcendor RR, Gao S, Zhai P, et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 2007; 100: 1512-21
-
(2007)
Circ Res
, vol.100
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
-
62
-
-
78650691023
-
Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes
-
Hariharan N, Maejima Y, Nakae J, et al. Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes. Circ Res 2010; 107: 1470-82.
-
(2010)
Circ Res
, vol.107
, pp. 1470-1482
-
-
Hariharan, N.1
Maejima, Y.2
Nakae, J.3
-
63
-
-
79953152333
-
FoxO1 mediates an auto feedback loop regulating SIRT1 expression
-
Xiong S, Salazar G, Patrushev N, Alexander RW. FoxO1 mediates an auto feedback loop regulating SIRT1 expression. J Biol Chem 2011; 286: 5289-99.
-
(2011)
J Biol Chem
, vol.286
, pp. 5289-5299
-
-
Xiong, S.1
Salazar, G.2
Patrushev, N.3
Alexander, R.W.4
-
64
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead dependent pathway
-
Nemoto S, Fergusson MM, Finkel T. Nutrient availability regulates SIRT1 through a forkhead dependent pathway. Science 2004; 306: 2105-8.
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
65
-
-
70349208608
-
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a dependent antioxidant defense mechanisms in mice
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, Gupta MP. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a dependent antioxidant defense mechanisms in mice. J. Clin. Invest 2009; 119: 2758-71.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
Gupta, M.P.6
-
66
-
-
51449083112
-
SIRT3 interacts with the daf-16 homolog FOXO3a in themitochondria, as well as increases FOXO3a dependent gene expression
-
Jacobs KM, Pennington JD, Bisht KS, et al. SIRT3 interacts with the daf-16 homolog FOXO3a in themitochondria, as well as increases FOXO3a dependent gene expression. Int. J. Biol. Sci 2008; 4: 291-9.
-
(2008)
Int. J. Biol. Sci
, vol.4
, pp. 291-299
-
-
Jacobs, K.M.1
Pennington, J.D.2
Bisht, K.S.3
-
67
-
-
58049125816
-
Relationship between oxidative stress and HIF-1 alpha mRNA during sustained hypoxia in humans
-
Pialoux V, Mounier R, Brown AD, Steinback CD, Rawling JM, Poulin MJ. Relationship between oxidative stress and HIF-1 alpha mRNA during sustained hypoxia in humans. Free Radic Biol Med 2009; 46(2): 321-6.
-
(2009)
Free Radic Biol Med
, vol.46
, Issue.2
, pp. 321-326
-
-
Pialoux, V.1
Mounier, R.2
Brown, A.D.3
Steinback, C.D.4
Rawling, J.M.5
Poulin, M.J.6
-
68
-
-
66749129781
-
Regulation of hypoxiainducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1
-
Dioum EM, Chen R, Alexander MS, et al. Regulation of hypoxiainducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1. Science 2009; 324: 1289-93.
-
(2009)
Science
, vol.324
, pp. 1289-1293
-
-
Dioum, E.M.1
Chen, R.2
Alexander, M.S.3
-
69
-
-
77955499804
-
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxiainducible factor 1alpha
-
Lim JH, Lee YM, Chun YS, Chen J, Kim JE, Park JW. Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxiainducible factor 1alpha. Mol. Cell 38: 864-878; 2010.
-
(2010)
Mol. Cell
, vol.38
, pp. 864-878
-
-
Lim, J.H.1
Lee, Y.M.2
Chun, Y.S.3
Chen, J.4
Kim, J.E.5
Park, J.W.6
-
70
-
-
74549142287
-
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha
-
Zhong L, D'Urso A, Toiber D, et al. The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell 2010; 140: 280-93.
-
(2010)
Cell
, vol.140
, pp. 280-293
-
-
Zhong, L.1
D'Urso, A.2
Toiber, D.3
-
71
-
-
74249092946
-
NF-kappaB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes
-
Mariappan N, Elks CM, Sriramula S, et al. NF-kappaB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes. Cardiovasc res 2010; 85(3): 473-83.
-
(2010)
Cardiovasc res
, vol.85
, Issue.3
, pp. 473-483
-
-
Mariappan, N.1
Elks, C.M.2
Sriramula, S.3
-
72
-
-
3242719545
-
Modulation of NF-jBdependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, et al. Modulation of NF-jBdependent transcription and cell survival by the SIRT1 deacetylase. EMBO 2004; 23(12): 2369-80.
-
(2004)
EMBO
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
-
73
-
-
78649738291
-
SIRT2 regulates NF-kB-dependent gene expression through deacetylation of p65 Lys310
-
Rothgiesser KM, Erener S, Waibel S, Lüscher B, Hottiger MO. SIRT2 regulates NF-kB-dependent gene expression through deacetylation of p65 Lys310. J Cell Sci 2010; 123: 4251-8.
-
(2010)
J Cell Sci
, vol.123
, pp. 4251-4258
-
-
Rothgiesser, K.M.1
Erener, S.2
Waibel, S.3
Lüscher, B.4
Hottiger, M.O.5
-
74
-
-
58149086403
-
When Sirtuins and NF-κB Collide
-
Gioacchino N, When Sirtuins and NF-κB Collide. Cell 2009; 136: 19-21.
-
(2009)
Cell
, vol.136
, pp. 19-21
-
-
Gioacchino, N.1
-
75
-
-
26644471251
-
Nitric oxide and mitochondrial biogenesis: A key to long-term regulation of cellular metabolism
-
Clementi E, Nisoli E. Nitric oxide and mitochondrial biogenesis: a key to long-term regulation of cellular metabolism. Comp Biochem Physiol A Mol Integr Physiol 2005; 142: 102-10.
-
(2005)
Comp Biochem Physiol A Mol Integr Physiol
, vol.142
, pp. 102-110
-
-
Clementi, E.1
Nisoli, E.2
-
76
-
-
35549008884
-
SIRT1 promotes endothelium-dependent vascu-lar relaxation by activating endothelial nitric oxide synthase
-
Mattagajasingh I, Kim CS, Naqvi A, et al. SIRT1 promotes endothelium-dependent vascu-lar relaxation by activating endothelial nitric oxide synthase. Proc. Natl. Acad. Sci 2007; 104: 14855-60.
-
(2007)
Proc. Natl. Acad. Sci
, vol.104
, pp. 14855-14860
-
-
Mattagajasingh, I.1
Kim, C.S.2
Naqvi, A.3
-
77
-
-
79953225194
-
Acetylation-Deacetylation of the Transcription Factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its Transcriptional Activity and Nucleo-cytoplasmic Localization
-
Yumiko K, LaKisha G, Melanie T, Jianqi Y, Ifeanyi JA. Acetylation-Deacetylation of the Transcription Factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its Transcriptional Activity and Nucleo-cytoplasmic Localization. J Biol Chem 2011; 286(9): 7629-40.
-
(2011)
J Biol Chem
, vol.286
, Issue.9
, pp. 7629-7640
-
-
Yumiko, K.1
LaKisha, G.2
Melanie, T.3
Jianqi, Y.4
Ifeanyi, J.A.5
-
78
-
-
84864277111
-
Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats
-
Bagul PK, Middela H, Matapally S, et al. Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. Pharmacol Res 2012; 66: 260-8.
-
(2012)
Pharmacol Res
, vol.66
, pp. 260-268
-
-
Bagul, P.K.1
Middela, H.2
Matapally, S.3
-
79
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T, Deng CX, Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 2009; 460(7255): 587-91.
-
(2009)
Nature
, vol.460
, Issue.7255
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
80
-
-
41549136422
-
Paths of convergence: Sirtuins in aging and neurodegeneration
-
Gan L, Mucke L. Paths of convergence: sirtuins in aging and neurodegeneration. Neuron 2008; 58 (1):10-4.
-
(2008)
Neuron
, vol.58
, Issue.1
, pp. 10-14
-
-
Gan, L.1
Mucke, L.2
-
81
-
-
0038268180
-
HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo
-
Hu Y, Mivechi NF. HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo. J Biol Chem 2003; 278: 17299-306.
-
(2003)
J Biol Chem
, vol.278
, pp. 17299-17306
-
-
Hu, Y.1
Mivechi, N.F.2
-
82
-
-
60749101582
-
Stress inducible regulation of heat shock factor 1 by the deacetylase SIRT1
-
Westerheide SD, Anckar J, Stevens SM Jr, Sistonen L, Morimoto RI. Stress inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 2009; 323: 1063-6
-
(2009)
Science
, vol.323
, pp. 1063-1066
-
-
Westerheide, S.D.1
Anckar, J.2
Stevens Jr., S.M.3
Sistonen, L.4
Morimoto, R.I.5
-
83
-
-
67649333085
-
DeubiKuitylation: A novel DUB enzymatic activity for the DNA repair protein, Ku70
-
Rathaus M, Lerrer B, Cohen HY. DeubiKuitylation: a novel DUB enzymatic activity for the DNA repair protein, Ku70. Cell Cycle 2009; 8: 1843-52.
-
(2009)
Cell Cycle
, vol.8
, pp. 1843-1852
-
-
Rathaus, M.1
Lerrer, B.2
Cohen, H.Y.3
-
84
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ, et al, Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004; 305: 390-2.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
-
85
-
-
79551514834
-
SIRT1 inhibits angiotensin II-induced vascular smooth muscle cell hypertrophy
-
Li Li, Gao P, Zhang H. SIRT1 inhibits angiotensin II-induced vascular smooth muscle cell hypertrophy. Acta Biochim Biophys Sin 2011, 43: 103-9
-
(2011)
Acta Biochim Biophys Sin
, vol.43
, pp. 103-109
-
-
Li, L.1
Gao, P.2
Zhang, H.3
-
86
-
-
80052142793
-
Restriction of Advanced Glycation End Products Improves Insulin Resistance in Human Type 2 Diabetes Potential role of AGER1 and SIRT1
-
Uribarri J, Cai W, Ramdas M. Restriction of Advanced Glycation End Products Improves Insulin Resistance in Human Type 2 Diabetes Potential role of AGER1 and SIRT1. Diabetes Care July 2011; 34: 1610-6.
-
(2011)
Diabetes Care July
, vol.34
, pp. 1610-1616
-
-
Uribarri, J.1
Cai, W.2
Ramdas, M.3
-
87
-
-
77149148756
-
Regulation of cellular metabolism by protein lysine acetylation
-
Zhao S, Xu W, Jiang W et al. Regulation of cellular metabolism by protein lysine acetylation. Science 2010; 327: 1000-4.
-
(2010)
Science
, vol.327
, pp. 1000-1004
-
-
Zhao, S.1
Xu, W.2
Jiang, W.3
-
88
-
-
37549002891
-
Mammalian Sir2 homolog SIRT3 regulates global mito-chondrial lysine acetylation
-
Lombard D, Alt W, Cheng L, et al. Mammalian Sir2 homolog SIRT3 regulates global mito-chondrial lysine acetylation. Mol Cell Biol 2007; 27: 8807-14.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8807-8814
-
-
Lombard, D.1
Alt, W.2
Cheng, L.3
-
89
-
-
84884270949
-
Superoxide levels and mitochondrial function are regulated by SIRT3
-
Jacobs KM, Gius D. Superoxide levels and mitochondrial function are regulated by SIRT3. Free Radic Biol Med 2007; 43: S156.
-
(2007)
Free Radic Biol Med
, vol.43
-
-
Jacobs, K.M.1
Gius, D.2
-
90
-
-
77956173286
-
SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity
-
Bao J, Scott I, Lu Z, et al. SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity. Free Radic. Biol. Med 2010; 49: 1230-7.
-
(2010)
Free Radic. Biol. Med
, vol.49
, pp. 1230-1237
-
-
Bao, J.1
Scott, I.2
Lu, Z.3
-
91
-
-
55749084738
-
Role for the mitochondrial deacetylase Sirt3in regulating energy homeostasis
-
Ahn BH, Kim HS, Song S, et al. Role for the mitochondrial deacetylase Sirt3in regulating energy homeostasis. Proc. Natl. Acad. Sci 2008; 105: 14447-52.
-
(2008)
Proc. Natl. Acad. Sci
, vol.105
, pp. 14447-14452
-
-
Ahn, B.H.1
Kim, H.S.2
Song, S.3
-
92
-
-
75349111140
-
Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
-
Cimen H, Han MJ, Yang Y, Tong Q, Koc H, Koc EC. Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry 2010; 49: 304-11.
-
(2010)
Biochemistry
, vol.49
, pp. 304-311
-
-
Cimen, H.1
Han, M.J.2
Yang, Y.3
Tong, Q.4
Koc, H.5
Koc, E.C.6
-
93
-
-
78649509214
-
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production
-
Shimazu T, Hirschey D, Hua L, et al. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab 2010; 12: 654-61.
-
(2010)
Cell Metab
, vol.12
, pp. 654-661
-
-
Shimazu, T.1
Hirschey, D.2
Hua, L.3
-
94
-
-
77957777952
-
Mitochondrial HMG-CoA synthase partially contributes to antioxidant protection in the kidney of strokeprone spontaneously hypertensive rats
-
Yi W, Fu P, Fan Z, et al. Mitochondrial HMG-CoA synthase partially contributes to antioxidant protection in the kidney of strokeprone spontaneously hypertensive rats. Nutrition 2010; 26: 1176-80.
-
(2010)
Nutrition
, vol.26
, pp. 1176-1180
-
-
Yi, W.1
Fu, P.2
Fan, Z.3
-
95
-
-
80051716282
-
Succinate dehydrogenase is a direct target of sirtuin 3 531 deacetylase activity
-
Finley W, Haas W, Desquiret-Dumas V, et al. Succinate dehydrogenase is a direct target of sirtuin 3 531 deacetylase activity. PLoS 2011; 6: e23295.
-
(2011)
PLoS
, vol.6
-
-
Finley, W.1
Haas, W.2
Desquiret-Dumas, V.3
-
96
-
-
79959819034
-
SirT3 suppresses hypoxia 497 inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS pro-498 duction
-
Bell E, Emerling M, Ricoult S, Guarente L. SirT3 suppresses hypoxia 497 inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS pro-498 duction. Oncogene 2011; 30: 2986-96.
-
(2011)
Oncogene
, vol.30
, pp. 2986-2996
-
-
Bell, E.1
Emerling, M.2
Ricoult, S.3
Guarente, L.4
-
97
-
-
80052291180
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
Jing E, Emanuelli B, Hirschey M, et al. Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production PNAS 2011; 108: 14608-13.
-
(2011)
PNAS
, vol.108
, pp. 14608-14613
-
-
Jing, E.1
Emanuelli, B.2
Hirschey, M.3
-
98
-
-
79952266729
-
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy
-
Hafner V, Dai J, Gomes A, et al. Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging 2010; 2: 914-23.
-
(2010)
Aging
, vol.2
, pp. 914-923
-
-
Hafner, V.1
Dai, J.2
Gomes, A.3
-
100
-
-
50149103440
-
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5
-
Schlicker C, Gertz M, Papatheodorou P, Kachholz B, Becker CF, Steegborn C. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J Mol Biol 2008; 382: 790-801.
-
(2008)
J Mol Biol
, vol.382
, pp. 790-801
-
-
Schlicker, C.1
Gertz, M.2
Papatheodorou, P.3
Kachholz, B.4
Becker, C.F.5
Steegborn, C.6
-
101
-
-
17144424946
-
SIRT3, a Mitochondrial Sirtuin Deacetylase, Regulates Mitochondrial Function and Thermogenesis in Brown Adipocytes
-
Tong S, Wang F, Stieren E, Tong Q. SIRT3, a Mitochondrial Sirtuin Deacetylase, Regulates Mitochondrial Function and Thermogenesis in Brown Adipocytes. The J Bio Chem 2005; 280: 13560-7.
-
(2005)
The J Bio Chem
, vol.280
, pp. 13560-13567
-
-
Tong, S.1
Wang, F.2
Stieren, E.3
Tong, Q.4
-
102
-
-
77955347446
-
Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
-
Kong X, Wang R, Xue Y, et al. Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One 2010; 5: e11707.
-
(2010)
PLoS One
, vol.5
-
-
Kong, X.1
Wang, R.2
Xue, Y.3
-
103
-
-
79951887419
-
Forkhead box O as a sensor, mediator, and regulator of redox signaling
-
de Keizer L, Burgering M, Dansen B. Forkhead box O as a sensor, mediator, and regulator of redox signaling. Antioxid. Redox Signal 2011; 14: 1093-106.
-
(2011)
Antioxid. Redox Signal
, vol.14
, pp. 1093-1106
-
-
de Keizer, L.1
Burgering, M.2
Dansen, B.3
-
104
-
-
77952940043
-
Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle
-
Palacios M, Carmona J, Michan S, et al. Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle. Aging 2009; 1: 771-83.
-
(2009)
Aging
, vol.1
, pp. 771-783
-
-
Palacios, M.1
Carmona, J.2
Michan, S.3
-
105
-
-
78651468722
-
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
Someya S, Yu W, Hallows WC, et al. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 2010; 143: 802-12.
-
(2010)
Cell
, vol.143
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
-
106
-
-
74049094817
-
SIRT3 is a mitochondrialocalized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
Kim HS, Patel K, Muldoon JK, et al. SIRT3 is a mitochondrialocalized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 2010; 17(1): 41-52.
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon, J.K.3
-
107
-
-
33746992118
-
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
-
Kim SC, Sprung R, Chen Y, et al. Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell 2006; 23: 607-18.
-
(2006)
Mol Cell
, vol.23
, pp. 607-618
-
-
Kim, S.C.1
Sprung, R.2
Chen, Y.3
-
108
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3 mediated SOD2 activation
-
Qiu, X, Brown K, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3 mediated SOD2 activation. Cell Metab 2010; 12: 662-7.
-
(2010)
Cell Metab
, vol.12
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
109
-
-
68949212379
-
Lysine acetylation targets protein complexes and coregulates major cellular functions
-
Choudhary C, Kumar C, Gnad F, et al. Lysine acetylation targets protein complexes and coregulates major cellular functions. Science 2009; 325: 834-40.
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
-
110
-
-
78650248160
-
Sirt3-mediated deacetylation of evolutionarily conserved lysine-122 regulates MnSOD activity in response to stress
-
Tao R, Coleman MC, Pennington JD, et al. Sirt3-mediated deacetylation of evolutionarily conserved lysine-122 regulates MnSOD activity in response to stress. Mol Cell 2010; 40: 893-904.
-
(2010)
Mol Cell
, vol.40
, pp. 893-904
-
-
Tao, R.1
Coleman, M.C.2
Pennington, J.D.3
-
111
-
-
79957979314
-
Tumor suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS
-
Chen Y, Zhang J, Lin Y, et al. Tumor suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS. EMBO Rep 2011; 12: 534-41.
-
(2011)
EMBO Rep
, vol.12
, pp. 534-541
-
-
Chen, Y.1
Zhang, J.2
Lin, Y.3
-
112
-
-
84855433458
-
The role of sirtuins in modulating redox stressors
-
Webster BR, Lu Z, Sack MN, Scott I. The role of sirtuins in modulating redox stressors. Free Radic Biol Med 2012; 52(2): 281-90.
-
(2012)
Free Radic Biol Med
, vol.52
, Issue.2
, pp. 281-290
-
-
Webster, B.R.1
Lu, Z.2
Sack, M.N.3
Scott, I.4
-
113
-
-
77955347446
-
Sirtuin 3, a New Target of PGC-1a, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis
-
Kong X, Wang R, Xue Y. Sirtuin 3, a New Target of PGC-1a, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis. PLoS ONE 2010; 5(7): e11707
-
(2010)
PLoS ONE
, vol.5
, Issue.7
-
-
Kong, X.1
Wang, R.2
Xue, Y.3
-
114
-
-
33748316536
-
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
-
Haigis MC, Mostoslavsky R, Haigis KM, et al. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells. Cell 2006; 126: 941-54.
-
(2006)
Cell
, vol.126
, pp. 941-954
-
-
Haigis, M.C.1
Mostoslavsky, R.2
Haigis, K.M.3
-
115
-
-
65249087389
-
SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle
-
Nakagawa T, Lomb DJ, Haigis MC, Guarente L. SIRT5 deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle. Cell 2009; 137: 560-70.
-
(2009)
Cell
, vol.137
, pp. 560-570
-
-
Nakagawa, T.1
Lomb, D.J.2
Haigis, M.C.3
Guarente, L.4
-
116
-
-
78651468707
-
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction
-
Hallows WC, Yu W, Smith BC, et al. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol. Cell 2011; 41: 139-49.
-
(2011)
Mol. Cell
, vol.41
, pp. 139-149
-
-
Hallows, W.C.1
Yu, W.2
Smith, B.C.3
-
117
-
-
79959363092
-
SIRT6 promotes DNA repair under stress by activating PARP1
-
Zhiyong M, Christopher H, Xiao T, et al. SIRT6 promotes DNA repair under stress by activating PARP1. Science 2011; 332: 1443-6.
-
(2011)
Science
, vol.332
, pp. 1443-1446
-
-
Zhiyong, M.1
Christopher, H.2
Xiao, T.3
-
118
-
-
41449083867
-
Sirt7 Increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
-
Olesya V, Christian S, Praveen G, et al. Sirt7 Increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice. Circ Res 2008; 102: 703-10.
-
(2008)
Circ Res
, vol.102
, pp. 703-710
-
-
Olesya, V.1
Christian, S.2
Praveen, G.3
-
119
-
-
34447569485
-
Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia
-
Kim SP, Catalano KJ, Hsu IR, Chiu J, Richey JM, Bergman RN. Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. Am J Physiol Endocrinol Metab 2007; 292: E1590-8.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Kim, S.P.1
Catalano, K.J.2
Hsu, I.R.3
Chiu, J.4
Richey, J.M.5
Bergman, R.N.6
-
120
-
-
80052678652
-
Molecular mechanisms of insulin resistance in type 2 diabetes mellitus
-
Saini V. Molecular mechanisms of insulin resistance in type 2 diabetes mellitus. World J Diabetes 2010; 1(3): 68-75.
-
(2010)
World J Diabetes
, vol.1
, Issue.3
, pp. 68-75
-
-
Saini, V.1
-
121
-
-
33244486764
-
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
-
Bordone L, Motta MC, Picard F et al. Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells. PLoS Biol 2006; 4: e31.
-
(2006)
PLoS Biol
, vol.4
-
-
Bordone, L.1
Motta, M.C.2
Picard, F.3
-
122
-
-
27744518040
-
FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction
-
Kitamura YI, Kitamura T, Kruse JP, et al. FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. Cell. Metab 2005; 2: 153-63.
-
(2005)
Cell. Metab
, vol.2
, pp. 153-163
-
-
Kitamura, Y.I.1
Kitamura, T.2
Kruse, J.P.3
-
123
-
-
38349112898
-
Age-associated loss of sirt1-mediated enhancement of glucose stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BesTO) mice
-
Ramsey KM, Mills KF, Satoh A, Imai S. Age-associated loss of sirt1-mediated enhancement of glucose stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BesTO) mice. Aging Cell 2008; 7: 78-88.
-
(2008)
Aging Cell
, vol.7
, pp. 78-88
-
-
Ramsey, K.M.1
Mills, K.F.2
Satoh, A.3
Imai, S.4
-
124
-
-
25144454432
-
Increased dosage of mammalian sir2 in pancreatic beta cells enhances glucosestimulated insulin secretion in mice
-
Moynihan KA, Grimm AA, Plueger MM, et al. Increased dosage of mammalian sir2 in pancreatic beta cells enhances glucosestimulated insulin secretion in mice. Cell Metab 2005; 2: 105-17.
-
(2005)
Cell Metab
, vol.2
, pp. 105-117
-
-
Moynihan, K.A.1
Grimm, A.A.2
Plueger, M.M.3
-
125
-
-
34548857700
-
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
-
Sun C, Zhang F, Ge X, et al. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell. Metab 2007; 6: 307-19.
-
(2007)
Cell. Metab
, vol.6
, pp. 307-319
-
-
Sun, C.1
Zhang, F.2
Ge, X.3
-
126
-
-
0029762957
-
Protein tyrosine phosphatase 1B interacts with the activated insulin receptor
-
Seely BL, Staubs PA, Reichart DR, et al. Protein tyrosine phosphatase 1B interacts with the activated insulin receptor. Diabetes 1996; 45: 1379-85.
-
(1996)
Diabetes
, vol.45
, pp. 1379-1385
-
-
Seely, B.L.1
Staubs, P.A.2
Reichart, D.R.3
-
127
-
-
0034635374
-
Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein
-
Goldstein BJ, Kowalczyk AB, White MF, Harbeck M. Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein. J Biol Chem 2000; 275: 4283-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 4283-4289
-
-
Goldstein, B.J.1
Kowalczyk, A.B.2
White, M.F.3
Harbeck, M.4
-
128
-
-
0032496150
-
Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2
-
Inoue G, Cheatham B, Emkey R. Kahn CR. Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2. J Biol Chem 1998: 273: 11548-55.
-
(1998)
J Biol Chem
, vol.273
, pp. 11548-11555
-
-
Inoue, G.1
Cheatham, B.2
Emkey, R.3
Kahn, C.R.4
-
129
-
-
36348974168
-
The direct involvement of SIRT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation
-
Zhang J. The direct involvement of SIRT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation. J Biol Chem 2007; 282: 34356-64.
-
(2007)
J Biol Chem
, vol.282
, pp. 34356-34364
-
-
Zhang, J.1
-
130
-
-
61749095297
-
SIRT 1 exerts antiinflammatory effects and improves insulin sensitivity in adipocytes
-
Yoshizaki T, Milne JC, Imamura T, et al. SIRT 1 exerts antiinflammatory effects and improves insulin sensitivity in adipocytes. Mol Cell Biol 2009; 29: 1363-74.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1363-1374
-
-
Yoshizaki, T.1
Milne, J.C.2
Imamura, T.3
-
131
-
-
0036092239
-
Banting, Dysregulation of fatty acid me in the etiology of type 2 diabetes
-
McGarry JD. Banting, Dysregulation of fatty acid me in the etiology of type 2 diabetes. Diabetes 2002; 51: 7-18.
-
(2002)
Diabetes
, vol.51
, pp. 7-18
-
-
McGarry, J.D.1
-
132
-
-
0035149738
-
Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats
-
Dobbins RL, Szczepaniak LS, Bentley B, Esser V, Myhill J, McGarry JD. Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats. Diabetes 2001; 50: 123-30.
-
(2001)
Diabetes
, vol.50
, pp. 123-130
-
-
Dobbins, R.L.1
Szczepaniak, L.S.2
Bentley, B.3
Esser, V.4
Myhill, J.5
McGarry, J.D.6
-
133
-
-
0344406146
-
Mechanisms of the free fatty acid-induced increase in hepatic glucose production
-
Lam TK, Carpentier A, Lewis GF, van de WG, Fantus IG, Giacca A. Mechanisms of the free fatty acid-induced increase in hepatic glucose production. Am J Physiol Endocrinol Metab 2003; 284: E863-73.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
-
-
Lam, T.K.1
Carpentier, A.2
Lewis, G.F.3
van De, W.G.4
Fantus, I.G.5
Giacca, A.6
-
134
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. Cellular mechanisms of insulin resistance. J. Clin. Invest 2000; 106: 171-6.
-
(2000)
J. Clin. Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
135
-
-
0023868703
-
Carbohydrate and lipid metabolism of skeletal muscle in type 2 diabetic patients
-
Falholt K, Jensen I, Lindkaer JS, et al. Carbohydrate and lipid metabolism of skeletal muscle in type 2 diabetic patients. Diabet Med 1988; 5: 27-31.
-
(1988)
Diabet Med
, vol.5
, pp. 27-31
-
-
Falholt, K.1
Jensen, I.2
Lindkaer, J.S.3
-
136
-
-
0030969532
-
Skeletal muscle triglyceride levels are inversely related to insulin action
-
Pan DA, Lillioja S, Kriketos AD, et al. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes 1997; 46: 983-8.
-
(1997)
Diabetes
, vol.46
, pp. 983-988
-
-
Pan, D.A.1
Lillioja, S.2
Kriketos, A.D.3
-
137
-
-
0033007207
-
Measurement of intracellular triglyceride stores by H spectroscopy: Validation in vivo
-
Szczepaniak LS, Babcock EE, Schick F, et al. Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. Am J Physiol 1999; 276: E977-89.
-
(1999)
Am J Physiol
, vol.276
-
-
Szczepaniak, L.S.1
Babcock, E.E.2
Schick, F.3
-
138
-
-
0035083842
-
Nonalcoholic steatohepatitis: Definition and pathology
-
Brunt EM. Nonalcoholic steatohepatitis: definition and pathology. Semin. Liver Dis 2001; 21(1): 3-16.
-
(2001)
Semin Liver Dis
, vol.21
, Issue.1
, pp. 3-16
-
-
Brunt, E.M.1
-
139
-
-
0033947158
-
Ability of insulin to modulate hepatic glucose production aging rats is impaired by fat accumulation
-
Gupta G, Cases JA, She L, et al. Ability of insulin to modulate hepatic glucose production aging rats is impaired by fat accumulation. Am J Physiol Endocrinol Metab 2000; 278: E985-91.
-
(2000)
Am J Physiol Endocrinol Metab
, vol.278
-
-
Gupta, G.1
Cases, J.A.2
She, L.3
-
140
-
-
0033958461
-
Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in O Long-Evans Tokushima fatty rats, a non-insulindependent diabetes model
-
Man ZW, Hirashima T, Mori, S, Kawano K. Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in O Long-Evans Tokushima fatty rats, a non-insulindependent diabetes model. Metabolism 2000; 49: 108-14.
-
(2000)
Metabolism
, vol.49
, pp. 108-114
-
-
Man, Z.W.1
Hirashima, T.2
Mori, S.3
Kawano, K.4
-
141
-
-
0342314436
-
Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients
-
Ryysy L, Hakkinen AM, Goto T, et al. Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. Diabetes 2000; 49: 749-58.
-
(2000)
Diabetes
, vol.49
, pp. 749-758
-
-
Ryysy, L.1
Hakkinen, A.M.2
Goto, T.3
-
142
-
-
0034830055
-
The effect of dietary polyunsaturated fatty acid on insulin sensitivity and lipid metabolism in Otsuka Long-Evans Tokushima Fatty (OLETF) rats
-
Sasagawa T, Ishii K, Hasuda K, Kubota M, Ota Y, Okita M. The effect of dietary polyunsaturated fatty acid on insulin sensitivity and lipid metabolism in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Prostaglandins Leukot. Essent Fatty Acids 2001; 64: 181-7.
-
(2001)
Prostaglandins Leukot. Essent Fatty Acids
, vol.64
, pp. 181-187
-
-
Sasagawa, T.1
Ishii, K.2
Hasuda, K.3
Kubota, M.4
Ota, Y.5
Okita, M.6
-
143
-
-
0036312905
-
Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
-
Lindroos SA, Vehkavaara S, Hakkinen AM, et al. Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 2002; 87: 3023-8.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3023-3028
-
-
Lindroos, S.A.1
Vehkavaara, S.2
Hakkinen, A.M.3
-
144
-
-
77953529312
-
Insulin resistance in nonalcoholic fatty liver disease
-
Bugianesi E, Moscatiello S, Ciaravella MF, Marchesini G. Insulin resistance in nonalcoholic fatty liver disease. Curr Pharm Des 2010; 16(17): 1941-51.
-
(2010)
Curr Pharm Des
, vol.16
, Issue.17
, pp. 1941-1951
-
-
Bugianesi, E.1
Moscatiello, S.2
Ciaravella, M.F.3
Marchesini, G.4
-
145
-
-
3042681042
-
SIRT 1 promotes fat mobilization in white adipocytes by repressing PPARγ
-
Picard F, Kurtev M, Chung N, et al. SIRT 1 promotes fat mobilization in white adipocytes by repressing PPARγ. Nature 2004; 429: 771-6.
-
(2004)
Nature
, vol.429
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
-
146
-
-
37549052177
-
Identification of a domain within peroxisome proliferator activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes
-
Wang H, Qiang L, Farmer SR. Identification of a domain within peroxisome proliferator activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes. Mol Cell Biol 2008; 28: 188-200.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 188-200
-
-
Wang, H.1
Qiang, L.2
Farmer, S.R.3
-
147
-
-
0242580872
-
Convergence of peroxisome proliferator activated receptor gamma and Foxo1 signaling pathways
-
Dowell P, Otto TC, Adi S, Lane MD. Convergence of peroxisome proliferator activated receptor gamma and Foxo1 signaling pathways. J Biol Chem 2003; 278: 45485-491.
-
(2003)
J Biol Chem
, vol.278
, pp. 45485-45491
-
-
Dowell, P.1
Otto, T.C.2
Adi, S.3
Lane, M.D.4
-
149
-
-
33845985335
-
SIRT1 regulates adiponectin gene expression through Foxo1 C/enhancer binding protein alpha transcriptional complex
-
Qiao L, Shao J. SIRT1 regulates adiponectin gene expression through Foxo1 C/enhancer binding protein alpha transcriptional complex. J Biol Chem 2006; 281: 39915-24.
-
(2006)
J Biol Chem
, vol.281
, pp. 39915-39924
-
-
Qiao, L.1
Shao, J.2
-
150
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1. Nature 2005; 434: 113-8.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
151
-
-
80555146753
-
Hepatic SIRT1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance
-
Rui HW, Kim HS, Xiao C, Xu X, Gavrilova O, Deng C. Hepatic SIRT1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance, J Clin Invest 2011; 121(11): 4477-90.
-
(2011)
J Clin Invest
, vol.121
, Issue.11
, pp. 4477-4490
-
-
Rui, H.W.1
Kim, H.S.2
Xiao, C.3
Xu, X.4
Gavrilova, O.5
Deng, C.6
-
152
-
-
50649112638
-
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase
-
Hou X, Xu S, Maitland-Toolan KA, et al. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J Biol Chem 2008; 283: 20015-26.
-
(2008)
J Biol Chem
, vol.283
, pp. 20015-20026
-
-
Hou, X.1
Xu, S.2
Maitland-Toolan, K.A.3
-
153
-
-
0043244921
-
SIR2 regulates skeletal muscle differentiation as a potential sensor of the redox state
-
Fulco M, Schiltz RL, Iezzi S, King MT, et al. SIR2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol Cell 2003; 12: 51-62.
-
(2003)
Mol Cell
, vol.12
, pp. 51-62
-
-
Fulco, M.1
Schiltz, R.L.2
Iezzi, S.3
King, M.T.4
-
154
-
-
15444377466
-
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
-
Bouras T, Fu M, Sauve AA, et al. SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem 2005; 280: 10264-76.
-
(2005)
J Biol Chem
, vol.280
, pp. 10264-10276
-
-
Bouras, T.1
Fu, M.2
Sauve, A.A.3
-
155
-
-
0035957375
-
Restoration of insulin sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcription coactivator PGC-1
-
Michael LF, Wu Z, Cheatham RB, et al. Restoration of insulin sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcription coactivator PGC-1. Proc. Natl Acad Sci 2001; 98: 3820-5.
-
(2001)
Proc. Natl Acad Sci
, vol.98
, pp. 3820-3825
-
-
Michael, L.F.1
Wu, Z.2
Cheatham, R.B.3
-
156
-
-
34247259630
-
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1 alpha
-
Gerhart-Hines Z, Rodgers JT, Bare O, et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1 alpha. EMBO 2007; 26(7): 1913-23.
-
(2007)
EMBO
, vol.26
, Issue.7
, pp. 1913-1923
-
-
Gerhart-Hines, Z.1
Rodgers, J.T.2
Bare, O.3
-
157
-
-
79955661493
-
Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver
-
Li Y, Xu S, Giles A, Nakamura K. Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver. FASEB J 2011; 25: 1664-79.
-
(2011)
FASEB J
, vol.25
, pp. 1664-1679
-
-
Li, Y.1
Xu, S.2
Giles, A.3
Nakamura, K.4
-
158
-
-
84861712572
-
SIRT1 attenuates palmitateinduced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150
-
Jung TW, Lee KT, Lee MW, Ka KH. SIRT1 attenuates palmitateinduced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150. Biochem Biophys Res Commun 2012; 422: 229-32.
-
(2012)
Biochem Biophys Res Commun
, vol.422
, pp. 229-232
-
-
Jung, T.W.1
Lee, K.T.2
Lee, M.W.3
Ka, K.H.4
-
159
-
-
64049089450
-
SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPAR-γ
-
Wang F, Tong Q. SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPAR-γ, Mol Bio Cell 2009; 20: 801-8.
-
(2009)
Mol Bio Cell
, vol.20
, pp. 801-808
-
-
Wang, F.1
Tong, Q.2
-
160
-
-
80052291180
-
Sirtuin-3 (SIRT3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
Jinga E, Emanuellia B, Hirscheyb MD, et al. Sirtuin-3 (SIRT3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci, 2011; 108(35): 14608-13.
-
(2011)
Proc Natl Acad Sci
, vol.108
, Issue.35
, pp. 14608-14613
-
-
Jinga, E.1
Emanuellia, B.2
Hirscheyb, M.D.3
-
161
-
-
82455212901
-
SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome
-
Hirschey MD, Shimazu T, Jing E, et al. SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome, Molecular Cell 2011; 44: 1-14.
-
(2011)
Molecular Cell
, vol.44
, pp. 1-14
-
-
Hirschey, M.D.1
Shimazu, T.2
Jing, E.3
-
162
-
-
77957762687
-
SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells
-
Nasrin N, Wu X, Fortier E, et al. SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells. J Bio Chem 2010; 285(42): 31995-2002
-
(2010)
J Bio Chem
, vol.285
, Issue.42
, pp. 31995-32002
-
-
Nasrin, N.1
Wu, X.2
Fortier, E.3
-
163
-
-
33748199578
-
Insulin secretion: SIRT4 gets in on the act
-
Argmann C, Auwerx J. Insulin secretion: SIRT4 gets in on the act. Cell 2006; 126(5): 837-9.
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 837-839
-
-
Argmann, C.1
Auwerx, J.2
-
164
-
-
36349030394
-
Regulation Of Insulin Secretion By Sirt4, A Mitochondrial ADP-Ribosyltransferase
-
Ahuja N, Schwer B, Carobbio S, et al. Regulation Of Insulin Secretion By Sirt4, A Mitochondrial ADP-Ribosyltransferase, J Bio Chem 2007; 282: 33583-92.
-
(2007)
J Bio Chem
, vol.282
, pp. 33583-33592
-
-
Ahuja, N.1
Schwer, B.2
Carobbio, S.3
-
165
-
-
78449248442
-
SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice
-
Xiao C, Kim HS, Lahusen T, SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice. JBiol Chem 2010; 285(47): 36776-84.
-
(2010)
J Biol Chem
, vol.285
, Issue.47
, pp. 36776-36784
-
-
Xiao, C.1
Kim, H.S.2
Lahusen, T.3
-
166
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi Y, Naiman S, Amir G, et al. The sirtuin SIRT6 regulates lifespan in male mice. Nature 2012; 05: 3-6.
-
(2012)
Nature
, vol.5
, pp. 3-6
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
-
167
-
-
0028961110
-
Diabetes and cardiovascular disease. The "common soil" hypothesis
-
Stern MP. Diabetes and cardiovascular disease. The "common soil" hypothesis. Diabetes 1995; 44: 369-74.
-
(1995)
Diabetes
, vol.44
, pp. 369-374
-
-
Stern, M.P.1
-
168
-
-
0035140346
-
Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by micro molar concentrations of lipoic acid
-
Maddux BA, See W, Lawrence JC, Goldfine AL, Goldfine ID, Evans JL. Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by micro molar concentrations of lipoic acid. Diabetes 2001; 50: 404-10.
-
(2001)
Diabetes
, vol.50
, pp. 404-410
-
-
Maddux, B.A.1
See, W.2
Lawrence, J.C.3
Goldfine, A.L.4
Goldfine, I.D.5
Evans, J.L.6
-
169
-
-
0034671429
-
Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of alpha-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress
-
Tretter L, Adam-Vizi V. Inhibition of Krebs cycle enzymes by hydrogen peroxide: a key role of alpha-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress. J Neurosci 2000; 20: 8972-79.
-
(2000)
J Neurosci
, vol.20
, pp. 8972-8979
-
-
Tretter, L.1
Adam-Vizi, V.2
-
170
-
-
0031683542
-
Pro-longed oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes
-
Rudich A, Tirosh A, Potashnik R, Hemi R, Kanety H, Bashan N. Pro-longed oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes. Diabetes 1998; 47: 1562-9.
-
(1998)
Diabetes
, vol.47
, pp. 1562-1569
-
-
Rudich, A.1
Tirosh, A.2
Potashnik, R.3
Hemi, R.4
Kanety, H.5
Bashan, N.6
-
171
-
-
0042804808
-
Increased glucose uptake promotes oxidative stress and PKC delta activation in adipocytes of obese, insulin-resistant mice
-
Talior I, Yarkoni M, Bashan N, Fielman EH. Increased glucose uptake promotes oxidative stress and PKC delta activation in adipocytes of obese, insulin-resistant mice. Am J Physiol 2003; 285: E295-302.
-
(2003)
Am J Physiol
, vol.285
-
-
Talior, I.1
Yarkoni, M.2
Bashan, N.3
Fielman, E.H.4
-
172
-
-
0032840875
-
Oral administration of RACalpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: A placebo-controlled pilot trial
-
Jacob S, Ruus P, Hermann R, et al. Oral administration of RACalpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radic Biol Med 1999; 27: 309-14.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 309-314
-
-
Jacob, S.1
Ruus, P.2
Hermann, R.3
-
173
-
-
0029742327
-
The antioxidant alpha-lipoic acid enhances insulin-stimulated glucose metabolism in insulinresistant rat skeletal muscle
-
Jacob S, Streeper RS, Fogt DL, et al. The antioxidant alpha-lipoic acid enhances insulin-stimulated glucose metabolism in insulinresistant rat skeletal muscle. Diabetes 1996; 45: 1024-1029.
-
(1996)
Diabetes
, vol.45
, pp. 1024-1029
-
-
Jacob, S.1
Streeper, R.S.2
Fogt, D.L.3
-
174
-
-
0036182681
-
Prevention of hypertension, insulin resistance and oxidative stress by a-lipoic acid
-
Midaoui A, Champlain J. Prevention of hypertension, insulin resistance and oxidative stress by a-lipoic acid. Hypertension 2002; 39: 303-7.
-
(2002)
Hypertension
, vol.39
, pp. 303-307
-
-
Midaoui, A.1
Champlain, J.2
-
175
-
-
0037154310
-
Antioxidative properties of acetylsalicylic acid on vascular tissues from normotensive and spontaneously hypertensive rats
-
Wu R, Lamontagne D, Champlain J. Antioxidative properties of acetylsalicylic acid on vascular tissues from normotensive and spontaneously hypertensive rats. Circulation 2002; 105: 387-92.
-
(2002)
Circulation
, vol.105
, pp. 387-392
-
-
Wu, R.1
Lamontagne, D.2
Champlain, J.3
-
176
-
-
0036628762
-
Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats
-
Midaoui A, Wu R, Champlain J. Prevention of hypertension, hyperglycemia and vascular oxidative stress by aspirin treatment in chronically glucose-fed rats. J Hypertens 2002; 20: 1407-12.
-
(2002)
J Hypertens
, vol.20
, pp. 1407-1412
-
-
Midaoui, A.1
Wu, R.2
Champlain, J.3
-
177
-
-
33744946526
-
Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats
-
Su H, Hung L, Chen J. Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats. Am J Physiol Endocrinol Metab 2006; 290: E1339-46.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Su, H.1
Hung, L.2
Chen, J.3
-
178
-
-
0030042738
-
Oxidative stress and insulin action. Is there a relationship?
-
Paolisso, G., Giugliano, D. Oxidative stress and insulin action. Is there a relationship? Diabetologia 1996; 39: 357-63.
-
(1996)
Diabetologia
, vol.39
, pp. 357-363
-
-
Paolisso, G.1
Giugliano, D.2
-
179
-
-
0042093769
-
New insights on oxidative stress and diabetic complications may lead to a 'causal' antioxidant therapy
-
Ceriello, A. New insights on oxidative stress and diabetic complications may lead to a 'causal' antioxidant therapy. Diabetes Care 2003; 26: 1589-96.
-
(2003)
Diabetes Care
, vol.26
, pp. 1589-1596
-
-
Ceriello, A.1
-
180
-
-
80054084256
-
Ectopic fat storage, insulin resistance, and hypertension
-
Sironi AM, Sicari R, Folli F, Gastaldelli A. Ectopic fat storage, insulin resistance, and hypertension. Curr Pharm Des 2011; 17(28): 3074-80.
-
(2011)
Curr Pharm Des
, vol.17
, Issue.28
, pp. 3074-3080
-
-
Sironi, A.M.1
Sicari, R.2
Folli, F.3
Gastaldelli, A.4
-
181
-
-
0029933643
-
The cellular and molecular mechanisms of diabetic complications
-
King GL, Brownlee M. The cellular and molecular mechanisms of diabetic complications. Endocrinol Metab Clin North Am 1996; 25: 255-70.
-
(1996)
Endocrinol Metab Clin North Am
, vol.25
, pp. 255-270
-
-
King, G.L.1
Brownlee, M.2
-
182
-
-
0030871260
-
Vascular dysfunction in diabetes mellitus
-
Fenner E, King GL, Vascular dysfunction in diabetes mellitus. Lancet 1997; 350 (1): 9-13.
-
(1997)
Lancet
, vol.350
, Issue.1
, pp. 9-13
-
-
Fenner, E.1
King, G.L.2
-
183
-
-
0027465289
-
The role of oxygen radicals in human disease, with particular reference to the vascular system
-
Halliwell B. The role of oxygen radicals in human disease, with particular reference to the vascular system. Haemostasis 1993; 23(1): 118-26.
-
(1993)
Haemostasis
, vol.23
, Issue.1
, pp. 118-126
-
-
Halliwell, B.1
-
184
-
-
0028897751
-
Diabetes mellitus, hypertension, and cardiovascular disease: Which role for oxidative stress?
-
Giugliano D, Ceriello A, Paolisso G. Diabetes mellitus, hypertension, and cardiovascular disease: which role for oxidative stress? Metabolism 1995; 44: 363-8.
-
(1995)
Metabolism
, vol.44
, pp. 363-368
-
-
Giugliano, D.1
Ceriello, A.2
Paolisso, G.3
-
185
-
-
0030797118
-
Antioxidant status in patients with uncomplicated insulin-dependent and noninsulindependent diabetes mellitus
-
Maxwell SRJ, Thomason H, Sandler D et al. Antioxidant status in patients with uncomplicated insulin-dependent and noninsulindependent diabetes mellitus. Eur J Clin Invest 1997; 27: 484-90.
-
(1997)
Eur J Clin Invest
, vol.27
, pp. 484-490
-
-
Maxwell, S.R.J.1
Thomason, H.2
Sandler, D.3
-
186
-
-
0028786096
-
Elevated levels of authentic plasma hydroperoxides in NIDDM
-
Zadeh NJ, Sarmadi TJ, Mccarthy S, Betteridge DJ, Wolff SP. Elevated levels of authentic plasma hydroperoxides in NIDDM. Diabetes 1995; 44: 1054-8.
-
(1995)
Diabetes
, vol.44
, pp. 1054-1058
-
-
Zadeh, N.J.1
Sarmadi, T.J.2
McCarthy, S.3
Betteridge, D.J.4
Wolff, S.P.5
-
187
-
-
0030743527
-
Relationships between plasma measures of oxidative stress and metabolic control in NIDDM
-
Zadeh NJ, Rahimi A, Sarmadi TJ. Relationships between plasma measures of oxidative stress and metabolic control in NIDDM. Diabetologia 1997; 40: 647-53.
-
(1997)
Diabetologia
, vol.40
, pp. 647-653
-
-
Zadeh, N.J.1
Rahimi, A.2
Sarmadi, T.J.3
-
188
-
-
0029917761
-
Antioxidant status and lipid peroxidation in type II diabetes mellitus with and without complications
-
Sundaram RK, Bhaskar A, Vijayalingam S, Viswanathan M, Mohan R, Shanmugasundaram KR. Antioxidant status and lipid peroxidation in type II diabetes mellitus with and without complications. Clin Sci 1996; 90: 255-60.
-
(1996)
Clin Sci
, vol.90
, pp. 255-260
-
-
Sundaram, R.K.1
Bhaskar, A.2
Vijayalingam, S.3
Viswanathan, M.4
Mohan, R.5
Shanmugasundaram, K.R.6
-
189
-
-
0028274304
-
Free radicals in diabetic endothelial cell dysfunction
-
Tesfamariam B Free radicals in diabetic endothelial cell dysfunction. Free Radic Biol Med 1994; 16: 383-91.
-
(1994)
Free Radic Biol Med
, vol.16
, pp. 383-391
-
-
Tesfamariam, B.1
-
190
-
-
0028845524
-
Treatment of symptomatic diabetic peripheral neuropathy with the antioxidant lipoic acid. A 3-week multicenter randomized controlled trial (ALADIN Study)
-
Ziegler D, Hanefeld M, Ruhnau KJ, et al. Treatment of symptomatic diabetic peripheral neuropathy with the antioxidant lipoic acid. A 3-week multicenter randomized controlled trial (ALADIN Study). Diabetologia 1995; 38: 1425-33.
-
(1995)
Diabetologia
, vol.38
, pp. 1425-1433
-
-
Ziegler, D.1
Hanefeld, M.2
Ruhnau, K.J.3
-
191
-
-
0032720953
-
The role of oxidative stress and NF-κB activation in late diabetic complications
-
Mohamed AK, Bierhaus A, Schiekofer S, Tritschler H, Ziegler R, Nawroth PP. The role of oxidative stress and NF-κB activation in late diabetic complications. Biofactors 1999; 10: 157-67.
-
(1999)
Biofactors
, vol.10
, pp. 157-167
-
-
Mohamed, A.K.1
Bierhaus, A.2
Schiekofer, S.3
Tritschler, H.4
Ziegler, R.5
Nawroth, P.P.6
-
192
-
-
44449114217
-
Advanced glycation end products and insulin resistance
-
Unoki H, Yamagishi S. Advanced glycation end products and insulin resistance. Curr Pharm Des 2008; 14(10): 987-9.
-
(2008)
Curr Pharm Des
, vol.14
, Issue.10
, pp. 987-989
-
-
Unoki, H.1
Yamagishi, S.2
-
193
-
-
0030358424
-
Dissection of protein kinase cascades that mediate cellular response to cytokines and cellular stress
-
Cohen P. Dissection of protein kinase cascades that mediate cellular response to cytokines and cellular stress. Adv Pharmacol 1996; 36: 15-27.
-
(1996)
Adv Pharmacol
, vol.36
, pp. 15-27
-
-
Cohen, P.1
-
194
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis JM, Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem 1996; 271: 24313-6.
-
(1996)
J Biol Chem
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
195
-
-
0033230607
-
Role of redox potential and reactive oxygen species in stress signaling
-
Adler V, Yin Z, Tew KD, Ronai Z. Role of redox potential and reactive oxygen species in stress signaling. Oncogene 1999; 18: 6104-11.
-
(1999)
Oncogene
, vol.18
, pp. 6104-6111
-
-
Adler, V.1
Yin, Z.2
Tew, K.D.3
Ronai, Z.4
-
196
-
-
0038314460
-
Oligofructose protects against the hypertriglyceridemia and prooxidative effects of a high fructose diet in rats
-
Busserolles J, Gueux E, Rock E, Demigne C, Mazur A, Rayssiguier Y. Oligofructose protects against the hypertriglyceridemia and prooxidative effects of a high fructose diet in rats. J Nutr 2003; 133: 1903-8.
-
(2003)
J Nutr
, vol.133
, pp. 1903-1908
-
-
Busserolles, J.1
Gueux, E.2
Rock, E.3
Demigne, C.4
Mazur, A.5
Rayssiguier, Y.6
-
197
-
-
13444282663
-
Effect of taurine on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats
-
Nandhini AT, Thirunavukkarasu V, Ravichandran MK, Anuradha CV. Effect of taurine on biomarkers of oxidative stress in tissues of fructose-fed insulin-resistant rats. SingaporeMed. J 2005; 46: 82-7.
-
(2005)
SingaporeMed. J
, vol.46
, pp. 82-87
-
-
Nandhini, A.T.1
Thirunavukkarasu, V.2
Ravichandran, M.K.3
Anuradha, C.V.4
-
198
-
-
37549054120
-
Conjugated linoleic acid and car-diac health: Oxidative stress and energetic metabolism in standard and sucrose-rich diets
-
Diniz YS, Santos PP, Assalin HB, et al. Conjugated linoleic acid and car-diac health: Oxidative stress and energetic metabolism in standard and sucrose-rich diets. Eur. J. Pharmacol 2008; 579: 318-25.
-
(2008)
Eur. J. Pharmacol
, vol.579
, pp. 318-325
-
-
Diniz, Y.S.1
Santos, P.P.2
Assalin, H.B.3
-
199
-
-
16244384612
-
Cardiac lipids and antioxidant status in high fructose rats and the effect of alpha-lipoic acid
-
Thirunavukkarasu V, Anitha Nandhini AT, Anuradha CV. Cardiac lipids and antioxidant status in high fructose rats and the effect of alpha-lipoic acid. Nutr Metab Cardiovasc Dis 2004; 14: 351-7.
-
(2004)
Nutr Metab Cardiovasc Dis
, vol.14
, pp. 351-357
-
-
Thirunavukkarasu, V.1
Anitha Nandhini, A.T.2
Anuradha, C.V.3
-
200
-
-
69249106093
-
Cardioprotective effect of vitamin E: Rescues of diabetes induced cardiac malfunction, oxidative stress, and apoptosis in rat
-
Shirpoor A, Salami S, Khadem-Ansari MH, Ilkhanizadeh B, Pakdel FG, Khademvatani K. Cardioprotective effect of vitamin E: Rescues of diabetes induced cardiac malfunction, oxidative stress, and apoptosis in rat. J Diabetes Complications 2009; 23: 310-6.
-
(2009)
J Diabetes Complications
, vol.23
, pp. 310-316
-
-
Shirpoor, A.1
Salami, S.2
Khadem-Ansari, M.H.3
Ilkhanizadeh, B.4
Pakdel, F.G.5
Khademvatani, K.6
-
201
-
-
0027717694
-
Free radical effects on myocardial membrane microviscosity
-
Coetzee IH, Lochner A. Free radical effects on myocardial membrane microviscosity. Cardioscience 1993; 4: 205-15.
-
(1993)
Cardioscience
, vol.4
, pp. 205-215
-
-
Coetzee, I.H.1
Lochner, A.2
-
202
-
-
0037019963
-
Decreasing cellular hydrogen peroxide with cata-lase mimics the effects of hypoxia on the sensitivity of the Ltype Ca2+ channel to beta-adrenergic receptor stimulation in cardiac myocytes
-
Hool LC, Arthur PG. Decreasing cellular hydrogen peroxide with cata-lase mimics the effects of hypoxia on the sensitivity of the Ltype Ca2+ channel to beta-adrenergic receptor stimulation in cardiac myocytes. Circ Res 2002; 91: 601-9.
-
(2002)
Circ Res
, vol.91
, pp. 601-609
-
-
Hool, L.C.1
Arthur, P.G.2
-
203
-
-
1942521160
-
H2O2 regulates recombinant Ca2+ channel alpha1C subunits but does not mediate their sensitivity to acute hypoxia
-
Hudasek K, Brown ST, Fearon IM. H2O2 regulates recombinant Ca2+ channel alpha1C subunits but does not mediate their sensitivity to acute hypoxia. Biochem. Biophys. Res. Commun 2004; 318: 135-41.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.318
, pp. 135-141
-
-
Hudasek, K.1
Brown, S.T.2
Fearon, I.M.3
-
204
-
-
0033986996
-
Diabetes-induced metabolic abnormalities in myocardium: Effect of antioxidant therapy
-
Kowluru RA, Engerman RL, Kern TS. Diabetes-induced metabolic abnormalities in myocardium: Effect of antioxidant therapy. Free Radic Res 2000; 32: 67-74.
-
(2000)
Free Radic Res
, vol.32
, pp. 67-74
-
-
Kowluru, R.A.1
Engerman, R.L.2
Kern, T.S.3
-
206
-
-
34249037557
-
Oxygen free radicals in the failing myocardium
-
Tomomi I, Hisojuki J. Oxygen free radicals in the failing myocardium. Circulation Res 1999; 85: 357-63
-
(1999)
Circulation Res
, vol.85
, pp. 357-363
-
-
Tomomi, I.1
Hisojuki, J.2
-
207
-
-
0033672337
-
Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species
-
Bassege E, Sommer O, Schwemmar M, Bunger R. Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species. Am J Physiol 2000; 279: H2431-8.
-
(2000)
Am J Physiol
, vol.279
-
-
Bassege, E.1
Sommer, O.2
Schwemmar, M.3
Bunger, R.4
-
208
-
-
17544379019
-
Direct evidence of increased hydroxyl radical in the failing myocardium
-
Tomomi I, Tsutsui H, Kingugaw S. Direct evidence of increased hydroxyl radical in the failing myocardium. Circ Res 2000; 186: 152-7.
-
(2000)
Circ Res
, vol.186
, pp. 152-157
-
-
Tomomi, I.1
Tsutsui, H.2
Kingugaw, S.3
-
209
-
-
65649098380
-
Energy metabolism in the normal and in the diabetic heart
-
Barsotti A, Giannoni A, Di Napoli P, Emdin M. Energy metabolism in the normal and in the diabetic heart. Curr Pharm Des 2009; 15(8): 836-40.
-
(2009)
Curr Pharm Des
, vol.15
, Issue.8
, pp. 836-840
-
-
Barsotti, A.1
Giannoni, A.2
Di Napoli, P.3
Emdin, M.4
-
210
-
-
57349195531
-
Optimization of cardiac metabolism in diabetes mellitus
-
Vitale C, Collin P. Optimization of cardiac metabolism in diabetes mellitus. Curr Pharm Des 2008; 14(25): 2537-50.
-
(2008)
Curr Pharm Des
, vol.14
, Issue.25
, pp. 2537-2550
-
-
Vitale, C.1
Collin, P.2
-
211
-
-
0032191856
-
Insulin action and insulin resistance: Diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system
-
Hunter SJ, Garvey WT. Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system. Am J Med 1998; 105: 331-45.
-
(1998)
Am J Med
, vol.105
, pp. 331-345
-
-
Hunter, S.J.1
Garvey, W.T.2
-
212
-
-
0028433421
-
Role of insulin resistance and hyperinsulinemia in development of hypertension and atherosclerosis
-
Sowers JR, Sowers PS, Peuler JD. Role of insulin resistance and hyperinsulinemia in development of hypertension and atherosclerosis. J Lab Clin Med 1994; 123: 647-52.
-
(1994)
J Lab Clin Med
, vol.123
, pp. 647-652
-
-
Sowers, J.R.1
Sowers, P.S.2
Peuler, J.D.3
-
213
-
-
0030025673
-
Hypertension and associated metabolic abnormalities the role of insulin resistance and the sympathoadrenal system
-
Reaven GM, Lithell H, Landsberg L. Hypertension and associated metabolic abnormalities the role of insulin resistance and the sympathoadrenal system. N Engl J Med 1996; 334: 374-81.
-
(1996)
N Engl J Med
, vol.334
, pp. 374-381
-
-
Reaven, G.M.1
Lithell, H.2
Landsberg, L.3
-
214
-
-
61449230001
-
Abnormal insulin signaling: Early detection of silent coronary artery disease erectile dysfunction?
-
Potenza MA, Montagnani M. Abnormal insulin signaling: early detection of silent coronary artery disease erectile dysfunction? Curr Pharm Des 2008; 14(35): 3737-48.
-
(2008)
Curr Pharm Des
, vol.14
, Issue.35
, pp. 3737-3748
-
-
Potenza, M.A.1
Montagnani, M.2
-
215
-
-
21044443182
-
Diabetic vascular complications: Pathophysiology, biochemical basis and potential therapeutic strategy
-
Yamagishi S, Imaizumi T. Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy. Curr Pharm Des 2005; 11(18): 2279-99.
-
(2005)
Curr Pharm Des
, vol.11
, Issue.18
, pp. 2279-2299
-
-
Yamagishi, S.1
Imaizumi, T.2
-
216
-
-
0021928037
-
Insulin as a growth factor
-
Hill DJ, Milner RD. Insulin as a growth factor. Pediatr Res 1985; 19: 879-86.
-
(1985)
Pediatr Res
, vol.19
, pp. 879-886
-
-
Hill, D.J.1
Milner, R.D.2
-
217
-
-
0027336865
-
Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes
-
Ito H, Hiroe M, Hirata Y, et al. Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes. Circulation 1993; 87: 1715-21.
-
(1993)
Circulation
, vol.87
, pp. 1715-1721
-
-
Ito, H.1
Hiroe, M.2
Hirata, Y.3
-
218
-
-
78149409465
-
Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease
-
Ren J, Pulakat L, Whaley-Connell A, Sowers JR. Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. J Mol Med 2010; 88: 993-1001.
-
(2010)
J Mol Med
, vol.88
, pp. 993-1001
-
-
Ren, J.1
Pulakat, L.2
Whaley-Connell, A.3
Sowers, J.R.4
-
219
-
-
0022639077
-
Superoxide dismutase plus catalase improve contractile function in the canine model of the "stunned myocardium"
-
Przyklenk K, Kloner RA. Superoxide dismutase plus catalase improve contractile function in the canine model of the "stunned myocardium". Circ Res 1986; 58: 148-56.
-
(1986)
Circ Res
, vol.58
, pp. 148-156
-
-
Przyklenk, K.1
Kloner, R.A.2
-
220
-
-
33646519886
-
Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: Role of oxidative stress, protein carbonyl formation and insulin sensitivity
-
Dong F, Fang CX, Yang X, Zhang X, Lopez FL, Ren J. Cardiac overexpression of catalase rescues cardiac contractile dysfunction induced by insulin resistance: Role of oxidative stress, protein carbonyl formation and insulin sensitivity. Diabetologia 2006; 49: 1421-33.
-
(2006)
Diabetologia
, vol.49
, pp. 1421-1433
-
-
Dong, F.1
Fang, C.X.2
Yang, X.3
Zhang, X.4
Lopez, F.L.5
Ren, J.6
-
222
-
-
78349299491
-
Surprising sirtuin crosstalk in the heart
-
Schug TT, Li X. Surprising sirtuin crosstalk in the heart. Aging 2010; 2(3): 129-32.
-
(2010)
Aging
, vol.2
, Issue.3
, pp. 129-132
-
-
Schug, T.T.1
Li, X.2
|