SIRT1 confers protection against UVB- and H 2O 2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes

Journal of Cellular and Molecular Medicine

Volumn 13, Issue 9 B, 2009, Pages 3632-3643

  Cao, Cong ^a,b   Lu, Shan ^a   Kivlin, Rebecca ^a   Wallin, Brittany ^a   Card, Elizabeth ^a   Bagdasarian, Andrew ^a   Tamakloe, Tyrone ^a   Wang, Wen jun ^c   Song, Xiuzu ^d   Chu, Wen Ming ^b   Kouttab, Nicola ^e   Xu, Aie ^d   Wan, Yinsheng ^a  

^a PROVIDENCE COLLEGE   (United States)

^b BROWN UNIVERSITY   (United States)

^c ZHEJIANG UNIVERSITY   (China)

^d The 3rd Hospital of Hangzhou   (China)

^e ROGER WILLIAMS MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Keratinocytes; P53; SIRT1; Skin aging; UV

Indexed keywords

HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SIRT1 PROTEIN, HUMAN; SIRT1 PROTEIN, MOUSE; SIRTUIN 1;

ANIMAL; ARTICLE; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CYTOLOGY; DOSE RESPONSE; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MOUSE; SKIN;

ANIMALS; CELL DEATH; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; MAP KINASE KINASE 4; MICE; REACTIVE OXYGEN SPECIES; SIRTUIN 1; SKIN; TUMOR SUPPRESSOR PROTEIN P53;

MAMMALIA;

EID: 77449121720     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00453.x     Document Type: Article

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