Oral administration of rac-α-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: A placebo-controlled pilot trial

Free Radical Biology and Medicine

Volumn 27, Issue 3-4, 1999, Pages 309-314

  Jacob, S ^a,c   Ruus, P ^b   Hermann, R ^b   Tritschler, H J ^b   Maerker, E ^c   Renn, W ^c   Augustin, H J ^a   Dietze, G J ^a   Rett, K ^c  

^a Hypertension and Diabet Res Unit   (Germany)

^b ASTA MEDICA AG   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Lipoic acid; Free radicals; Glucose clamp; Insulin resistance; Insulin stimulated glucose update; Radical scavenger; Type 2 diabetes mellitus

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; ORAL ANTIDIABETIC AGENT; PLACEBO; THIOCTIC ACID;

ADULT; AGED; ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; HUMAN; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; ANTHROPOMETRY; DIABETES MELLITUS, TYPE 2; FEMALE; FREE RADICAL SCAVENGERS; GLUCOSE CLAMP TECHNIQUE; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; PILOT PROJECTS; STEREOISOMERISM; THIOCTIC ACID;

EID: 0032840875     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00089-1     Document Type: Article

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