SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

Preventive Medicine

Volumn 54, Issue SUPPL., 2012, Pages

  Rahman, Irfan ^a   Kinnula, Vuokko L ^b   Gorbunova, Vera ^c   Yao, Hongwei ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

COPD; DNA damage response; FOXO3; Histone modifications; Inflammaging; NF B; Oxidative stress; Polyphenols; SIRT1; Tobacco smoke

Indexed keywords

ALDEHYDE; BETA CATENIN; CURCUMIN; DNA; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENVIRONMENTAL CHEMICAL; HISTONE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KLOTHO PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NOTCH RECEPTOR; OXIDIZING AGENT; POLYPHENOL DERIVATIVE; PROTEASOME INHIBITOR; PROTEIN; PROTEIN P53; QUERCETIN; RESVERATROL; SERINE; SIRTINOL; SIRTUIN 1; SRT 1720; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; UNINDEXED DRUG; WERNER SYNDROME PROTEIN; WNT PROTEIN;

AGING; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; AUTOPHAGY; CARDIOVASCULAR FUNCTION; CELL AGING; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG TARGETING; HISTONE MODIFICATION; HISTOPATHOLOGY; HOMEOSTASIS; HUMAN; INFLAMMATION; LUNG DISEASE; LUNG EMPHYSEMA; LUNG FUNCTION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PNEUMONIA; PREVALENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; REVIEW; RISK FACTOR; SENESCENCE; SIGNAL TRANSDUCTION; SMOKING; SYMPTOM; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AGING, PREMATURE; CELL AGING; DNA DAMAGE; HUMANS; OXIDATIVE STRESS; POLYPHENOLS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; SIRTUIN 1;

EID: 84860880317     PISSN: 00917435     EISSN: 10960260     Source Type: Journal    
DOI: 10.1016/j.ypmed.2011.11.014     Document Type: Review

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