Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease

Neurobiology of Aging

Volumn 33, Issue 9, 2012, Pages 2062-2071

  Chang, Jaewon ^a   Rimando, Agnes ^b   Pallas, Merce ^c   Camins, Antoni ^c   Porquet, David ^c   Reeves, Jennifer ^a   Shukitt Hale, Barbara ^d   Smith, Mark A ^a   Joseph, James A ^d   Casadesus, Gemma ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b NATURAL PRODUCTS UTILIZATION RESEARCH UNIT   (United States)

^c UNIVERSITY OF BARCELONA   (Spain)

^d TUFTS UNIVERSITY   (United States)

Author keywords

Aging; Alzheimer's disease; Cell signaling; Cognition; MnSOD; NKF beta; PPAR alpha; Pterostilbene; Resveratrol; SAMP8; Tau

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHENOL DERIVATIVE; PTEROSTILBENE; RESVERATROL; SIRTUIN 1; STRESS ACTIVATED PROTEIN KINASE; TAU PROTEIN; UNCLASSIFIED DRUG;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRESS; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; INFLAMMATION; LOW DRUG DOSE; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; VALIDATION PROCESS;

AGING; ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL AVAILABILITY; BRAIN; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE EXPRESSION REGULATION; MALE; MAP KINASE KINASE 4; MAZE LEARNING; MICE; NEUROTRANSMITTER AGENTS; PHOSPHORYLATION; PPAR ALPHA; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SIRTUIN 1; STILBENES; TAU PROTEINS;

EID: 84863498111     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2011.08.015     Document Type: Article

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