Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-κB in macrophages in vitro and in rat lungs in vivo: Implications for chronic inflammation and aging

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 2, 2007, Pages

  Yang, Se Ran ^a   Wright, Jessica ^a   Bauter, Mark ^a   Seweryniak, Kathryn ^a   Kode, Aruna ^a   Rahman, Irfan ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Acetylation; Chronic obstructive pulmonary disease; Deacetylase; Histone; MonoMac6 cells; Oxidants; Resveratrol

Indexed keywords

CIGARETTE SMOKE; ENZYME INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RESVERATROL; SIRT1 PROTEIN; SIRTINOL; SIRTUIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ACETYLATION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LUNG; LUNG LAVAGE; MACROPHAGE; MALE; MEDIATOR RELEASE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; TIME;

ACETYLATION; AGING; ANIMALS; BENZAMIDES; BRONCHOALVEOLAR LAVAGE FLUID; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-8; LUNG; MACROPHAGES; MODELS, IMMUNOLOGICAL; NAPHTHOLS; NEUTROPHILS; RATS; SIRTUINS; SMOKE; TOBACCO; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33847060910     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00308.2006     Document Type: Article

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