Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells

Biochemical and Biophysical Research Communications

Volumn 338, Issue 4, 2005, Pages 1805-1810

  Moonen, Harald J J ^a   Geraets, Liesbeth ^a   Vaarhorst, Anika ^a   Bast, Aalt ^a   Wouters, Emiel F M ^b   Hageman, Geja J ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

COPD; Histone deacetylase; Inflammation; NAD+; Oxidative stress; Poly(ADP ribose)polymerase 1; Skeletal muscle breakdown

Indexed keywords

HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; THEOPHYLLINE;

ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PURIFICATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; OXIDATIVE STRESS; PRIORITY JOURNAL;

CELL LINE, TUMOR; ENZYME ACTIVATION; EPITHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; KINETICS; LUNG; NAD; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; THEOPHYLLINE;

EID: 27844573349     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.159     Document Type: Article

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