Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases

Cell

Volumn 148, Issue 3, 2012, Pages 421-433

  Park, Sung Jun ^a   Ahmad, Faiyaz ^a   Philp, Andrew ^b   Baar, Keith ^b   Williams, Tishan ^c   Luo, Haibin ^d   Ke, Hengming ^c   Rehmann, Holger ^e   Taussig, Ronald ^f   Brown, Alexandra L ^a   Kim, Myung K ^a   Beaven, Michael A ^a   Burgin, Alex B ^g   Manganiello, Vincent ^a   Chung, Jay H ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d SUN YAT SEN UNIVERSITY   (China)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g Emerald BioStructures   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CELL PROTEIN; CYCLIC AMP; NICOTINAMIDE ADENINE DINUCLEOTIDE; PHOSPHODIESTERASE IV; PROTEIN EPAC1; RESVERATROL; ROLIPRAM; RYANODINE RECEPTOR 2; SIRTUIN 1; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CALORIC RESTRICTION; CONTROLLED STUDY; DIET; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; METABOLIC DISORDER; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; STAMEN;

MUS;

EID: 84863011114     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.01.017     Document Type: Article

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