Cigarette smoke induces nucleic-acid oxidation in lung fibroblasts

American Journal of Respiratory Cell and Molecular Biology

Volumn 43, Issue 5, 2010, Pages 576-584

  Deslee, Gaetan ^a,b   Adair Kirk, Tracy L ^a   Betsuyaku, Tomoko ^c   Woods, Jason C ^a,d   Moore, Carla H ^a   Gierada, David S ^d   Conradi, Susan H ^d   Atkinson, Jeffrey J ^a   Toennies, Holly M ^a   Battaile, John T ^a   Kobayashi, Dale K ^a   Patterson, G Alexander ^a   Holtzman, Michael J ^a   Pierce, Richard A ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b REIMS UNIVERSITY HOSPITAL   (France)

^c HOKKAIDO UNIVERSITY   (Japan)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

COPD; DNA RNA repair; Emphysema; Nucleic acid oxidation

Indexed keywords

8 OXOGUANINE DNA GLYCOSYLASE; ANTIOXIDANT; CIGARETTE SMOKE; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE III HOMOLOGUE 1 PROTEIN; MESSENGER RNA; NUCLEIC ACID; PROTEIN; REACTIVE OXYGEN METABOLITE; SINGLE STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; Y BOX BINDING PROTEIN 1; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA BINDING PROTEIN; NTHL1 PROTEIN, HUMAN; NUCLEAR PROTEIN; OXOGUANINE GLYCOSYLASE 1, HUMAN; SMUG1 PROTEIN, HUMAN; URACIL DNA GLYCOSIDASE; YBX1 PROTEIN, HUMAN;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ALVEOLUS CELL; LUNG EMPHYSEMA; LUNG FIBROBLAST; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; ADULT; ANIMAL; C57BL MOUSE; DOWN REGULATION; DRUG ANTAGONISM; EMPHYSEMA; ENZYMOLOGY; FIBROBLAST; GENETICS; LUNG; LUNG ALVEOLUS; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; PATHOLOGY; SMOKING;

MUS;

ADULT; AGED; ANIMALS; APOPTOSIS; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA GLYCOSYLASES; DNA-BINDING PROTEINS; DOWN-REGULATION; EMPHYSEMA; FEMALE; FIBROBLASTS; HUMANS; LUNG; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; NUCLEAR PROTEINS; NUCLEIC ACIDS; OXIDATION-REDUCTION; PULMONARY ALVEOLI; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SMOKING; URACIL-DNA GLYCOSIDASE;

EID: 78149251212     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0221OC     Document Type: Article

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