Genetic downregulation of AMPK-α isoforms uncovers the mechanism by which metformin decreases FA uptake and oxidation in skeletal muscle cells

American Journal of Physiology - Cell Physiology

Volumn 299, Issue 6, 2010, Pages

  Bogachus, Lindsey D ^a   Turcotte, Lorraine P ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

5 amino imidazole 4 carboxamide 1 D ribofuranoside, silent mating type information regulator 2 homolog 1; AMP activated protein kinase; Fatty acid; Fatty acid transporter CD36; Glucose uptake; Glut4

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYL COENZYME A CARBOXYLASE; FATTY ACID; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; METFORMIN; PALMITIC ACID; PROTEIN AMPK ALPHA 1; PROTEIN AMPK ALPHA 2; SIRTUIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; FATTY ACID METABOLISM; GLUCOSE TRANSPORT; INCUBATION TEMPERATURE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR DOWN REGULATION; SKELETAL MUSCLE;

ACETYL-COA CARBOXYLASE; AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; ANTIGENS, CD36; CELL LINE; DOWN-REGULATION; FATTY ACIDS; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HYPOGLYCEMIC AGENTS; INSULIN; METFORMIN; MUSCLE, SKELETAL; PALMITATES; PROTEIN KINASES; RATS; RIBONUCLEOTIDES; RNA INTERFERENCE; SIRTUIN 1;

EID: 78649649752     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00279.2010     Document Type: Article

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