Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences

International Journal of COPD

Volumn 6, Issue 1, 2011, Pages 209-217

  Gillespie, Markn ^a   Pastukh, Viktor M ^a   Zhang, Li ^b   Vruchko, Mykhaylo ^a   Gorodnya, Olena ^a   Bardwell, Gina C ^a   Tuder, Rubin M ^b  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

COPD; DNA damage; MtDNA; VEGF hypoxic response element

Indexed keywords

BETA ACTIN; EARLY GROWTH RESPONSE FACTOR 1; HEME OXYGENASE 1; HISTONE H2AX; MESSENGER RNA; MITOCHONDRIAL DNA; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN; H2AFX PROTEIN, HUMAN; HISTONE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ARTICLE; BETA ACTIN GENE; CELL FATE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; DNA STRAND BREAKAGE; EARLY GROWTH RESPONSE FACTOR 1 GENE; GENE; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC CODE; HEME OXYGENASE 1 GENE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS WALL; LUNG PARENCHYMA; MITOCHONDRIAL GENOME; MOLECULAR PATHOLOGY; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROMOTER REGION; SEQUENCE ANALYSIS; SOUTHERN BLOTTING; TRANSFORMING GROWTH FACTOR BETA1 GENE; VASCULOTROPIN GENE; ANALYSIS OF VARIANCE; CASE CONTROL STUDY; CHEMISTRY; CLINICAL TRIAL; DNA DAMAGE; GENETICS; HOSPITALIZATION; LUNG; METABOLISM; MULTICENTER STUDY; PATHOLOGY; UNITED STATES;

ANALYSIS OF VARIANCE; BALTIMORE; BLOTTING, SOUTHERN; CASE-CONTROL STUDIES; COLORADO; DNA DAMAGE; DNA, MITOCHONDRIAL; HISTONES; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80053502247     PISSN: 11769106     EISSN: 11782005     Source Type: Journal    
DOI: 10.2147/COPD.S15922     Document Type: Article

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