-
1
-
-
0345505676
-
Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish twin pairs: a nationwide follow-up study
-
Hyttinen, V., Kaprio, J., Kinnunen, L., Koskenvuo, M. & Tuomilehto, J. Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish twin pairs: a nationwide follow-up study. Diabetes 52, 1052-1055 (2003).
-
(2003)
Diabetes
, vol.52
, pp. 1052-1055
-
-
Hyttinen, V.1
Kaprio, J.2
Kinnunen, L.3
Koskenvuo, M.4
Tuomilehto, J.5
-
2
-
-
0027375302
-
Twin concordance rates for rheumatoid arthritis: results from a nationwide study
-
Silman, A.J. et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol 32, 903-907 (1993).
-
(1993)
Br J Rheumatol
, vol.32
, pp. 903-907
-
-
Silman, A.J.1
-
3
-
-
25844442849
-
Concordance for multiple sclerosis in Danish twins: an update of a nationwide study
-
Hansen, T. et al. Concordance for multiple sclerosis in Danish twins: an update of a nationwide study. Mult Scler 11, 504-510 (2005).
-
(2005)
Mult Scler
, vol.11
, pp. 504-510
-
-
Hansen, T.1
-
4
-
-
0026537198
-
A revised estimate of twin concordance in systemic lupus erythematosus
-
Deapen, D. et al. A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 35, 311-318 (1992).
-
(1992)
Arthritis Rheum
, vol.35
, pp. 311-318
-
-
Deapen, D.1
-
5
-
-
0031834892
-
A populationbased study of Graves' disease in Danish twins
-
Brix, T.H., Christensen, K., Holm, N.V., Harvald, B. & Hegedus, L. A populationbased study of Graves' disease in Danish twins. Clin Endocrinol (Oxf) 48, 397-400 (1998).
-
(1998)
Clin Endocrinol (Oxf)
, vol.48
, pp. 397-400
-
-
Brix, T.H.1
Christensen, K.2
Holm, N.V.3
Harvald, B.4
Hegedus, L.5
-
6
-
-
0034453053
-
A population-based study of chronic autoimmune hypothyroidism in Danish twins
-
Brix, T.H., Kyvik, K.O. & Hegedus, L. A population-based study of chronic autoimmune hypothyroidism in Danish twins. J Clin Endocrinol Metab 85, 536-539 (2000).
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 536-539
-
-
Brix, T.H.1
Kyvik, K.O.2
Hegedus, L.3
-
7
-
-
0033773642
-
Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study
-
Orholm, M., Binder, V., Sorensen, T.I., Rasmussen, L.P. & Kyvik, K.O. Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study. Scand J Gastroenterol 35, 1075-1081 (2000).
-
(2000)
Scand J Gastroenterol
, vol.35
, pp. 1075-1081
-
-
Orholm, M.1
Binder, V.2
Sorensen, T.I.3
Rasmussen, L.P.4
Kyvik, K.O.5
-
8
-
-
0034569180
-
Increased prevalence of autoimmune thyroid disease in patients with type 1 diabetes
-
Park, Y.S., Kim, T.W., Kim, W.B. & Cho, B.Y. Increased prevalence of autoimmune thyroid disease in patients with type 1 diabetes. Korean J Intern Med 15, 202-210 (2000).
-
(2000)
Korean J Intern Med
, vol.15
, pp. 202-210
-
-
Park, Y.S.1
Kim, T.W.2
Kim, W.B.3
Cho, B.Y.4
-
9
-
-
0024471672
-
Sjogren's syndrome: association with type-1 diabetes mellitus
-
Binder, A., Maddison, P.J., Skinner, P., Kurtz, A. & Isenberg, D.A. Sjogren's syndrome: association with type-1 diabetes mellitus. Br J Rheumatol 28, 518-520 (1989).
-
(1989)
Br J Rheumatol
, vol.28
, pp. 518-520
-
-
Binder, A.1
Maddison, P.J.2
Skinner, P.3
Kurtz, A.4
Isenberg, D.A.5
-
10
-
-
36749064496
-
Prevalence and clinical features of celiac disease in 950 children with type 1 diabetes in France
-
Poulain, C., Johanet, C., Delcroix, C., Levy-Marchal, C. & Tubiana-Rufi, N. Prevalence and clinical features of celiac disease in 950 children with type 1 diabetes in France. Diabetes Metab 33, 453-458 (2007).
-
(2007)
Diabetes Metab
, vol.33
, pp. 453-458
-
-
Poulain, C.1
Johanet, C.2
Delcroix, C.3
Levy-Marchal, C.4
Tubiana-Rufi, N.5
-
11
-
-
34247159923
-
Association between thyroid autoimmune dysfunction and non-thyroid autoimmune diseases
-
Cruz, A.A., Akaishi, P.M., Vargas, M.A. & de Paula, S.A. Association between thyroid autoimmune dysfunction and non-thyroid autoimmune diseases. Ophthal Plast Reconstr Surg 23, 104-108 (2007).
-
(2007)
Ophthal Plast Reconstr Surg
, vol.23
, pp. 104-108
-
-
Cruz, A.A.1
Akaishi, P.M.2
Vargas, M.A.3
de Paula, S.A.4
-
12
-
-
0031774623
-
Autoimmune thyroid diseases and coeliac disease
-
Sategna-Guidetti, C. et al. Autoimmune thyroid diseases and coeliac disease. Eur J Gastroenterol Hepatol 10, 927-931 (1998).
-
(1998)
Eur J Gastroenterol Hepatol
, vol.10
, pp. 927-931
-
-
Sategna-Guidetti, C.1
-
13
-
-
0028817212
-
Associated autoimmunity in Addison's disease
-
Zelissen, P.M., Bast, E.J. & Croughs, R.J. Associated autoimmunity in Addison's disease. J Autoimmun 8, 121-130 (1995).
-
(1995)
J Autoimmun
, vol.8
, pp. 121-130
-
-
Zelissen, P.M.1
Bast, E.J.2
Croughs, R.J.3
-
14
-
-
0038458877
-
Prevalence of autoimmune thyroiditis and non-immune thyroid disease in multiple sclerosis
-
Niederwieser, G. et al. Prevalence of autoimmune thyroiditis and non-immune thyroid disease in multiple sclerosis. J Neurol 250, 672-675 (2003).
-
(2003)
J Neurol
, vol.250
, pp. 672-675
-
-
Niederwieser, G.1
-
15
-
-
0033282731
-
Autoimmune thyroid disorders in juvenile chronic arthritis and systemic lupus erythematosus
-
Mihailova, D. et al. Autoimmune thyroid disorders in juvenile chronic arthritis and systemic lupus erythematosus. Adv Exp Med Biol 455, 55-60 (1999).
-
(1999)
Adv Exp Med Biol
, vol.455
, pp. 55-60
-
-
Mihailova, D.1
-
16
-
-
33646681230
-
Familial clustering of autoimmune diseases in patients with type 1 diabetes mellitus
-
Anaya, J.M. et al. Familial clustering of autoimmune diseases in patients with type 1 diabetes mellitus. J Autoimmun 26, 208-214 (2006).
-
(2006)
J Autoimmun
, vol.26
, pp. 208-214
-
-
Anaya, J.M.1
-
17
-
-
33750987918
-
Autoimmune disease aggregation in families with primary Sjogren's syndrome
-
Anaya, J.M., Tobon, G.J., Vega, P. & Castiblanco, J. Autoimmune disease aggregation in families with primary Sjogren's syndrome. J Rheumatol 33, 2227-2234 (2006).
-
(2006)
J Rheumatol
, vol.33
, pp. 2227-2234
-
-
Anaya, J.M.1
Tobon, G.J.2
Vega, P.3
Castiblanco, J.4
-
18
-
-
0037484670
-
Increased prevalence of autoimmune diseases in firstdegree relatives of patients with celiac disease
-
Cataldo, F. & Marino, V. Increased prevalence of autoimmune diseases in firstdegree relatives of patients with celiac disease. J Pediatr Gastroenterol Nutr 36, 470-473 (2003).
-
(2003)
J Pediatr Gastroenterol Nutr
, vol.36
, pp. 470-473
-
-
Cataldo, F.1
Marino, V.2
-
19
-
-
0034023587
-
Autoimmune disease in first-degree relatives of patients with multiple sclerosis. A UK survey
-
Broadley, S.A., Deans, J., Sawcer, S.J., Clayton, D. & Compston, D.A. Autoimmune disease in first-degree relatives of patients with multiple sclerosis. A UK survey. Brain 123 (Pt 6), 1102-1111 (2000).
-
(2000)
Brain
, vol.123
, Issue.PT 6
, pp. 1102-1111
-
-
Broadley, S.A.1
Deans, J.2
Sawcer, S.J.3
Clayton, D.4
Compston, D.A.5
-
20
-
-
0036069384
-
Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis
-
Prahalad, S., Shear, E.S., Thompson, S.D., Giannini, E.H. & Glass, D.N. Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rheumatoid arthritis. Arthritis Rheum 46, 1851-1856 (2002).
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1851-1856
-
-
Prahalad, S.1
Shear, E.S.2
Thompson, S.D.3
Giannini, E.H.4
Glass, D.N.5
-
21
-
-
0036746057
-
Long-term followup of children with neonatal lupus and their unaffected siblings
-
Martin, V., Lee, L.A., Askanase, A.D., Katholi, M. & Buyon, J.P. Long-term followup of children with neonatal lupus and their unaffected siblings. Arthritis Rheum 46, 2377-2383 (2002).
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2377-2383
-
-
Martin, V.1
Lee, L.A.2
Askanase, A.D.3
Katholi, M.4
Buyon, J.P.5
-
22
-
-
0031930209
-
Familial autoimmunity in pedigrees of idiopathic inflammatory myopathy patients suggests common genetic risk factors for many autoimmune diseases
-
Ginn, L.R. et al. Familial autoimmunity in pedigrees of idiopathic inflammatory myopathy patients suggests common genetic risk factors for many autoimmune diseases. Arthritis Rheum 41, 400-405 (1998).
-
(1998)
Arthritis Rheum
, vol.41
, pp. 400-405
-
-
Ginn, L.R.1
-
23
-
-
20244373351
-
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms
-
Vella, A. et al. Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet 76, 773-779 (2005).
-
(2005)
Am J Hum Genet
, vol.76
, pp. 773-779
-
-
Vella, A.1
-
24
-
-
33947274768
-
Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs
-
Brand, O.J. et al. Association of the interleukin-2 receptor alpha (IL-2Ralpha)/CD25 gene region with Graves' disease using a multilocus test and tag SNPs. Clin Endocrinol (Oxf) 66, 508-512 (2007).
-
(2007)
Clin Endocrinol (Oxf)
, vol.66
, pp. 508-512
-
-
Brand, O.J.1
-
25
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
Hafler, D.A. et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357, 851-862 (2007).
-
(2007)
N Engl J Med
, vol.357
, pp. 851-862
-
-
Hafler, D.A.1
-
26
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007).
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
27
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Bottini, N. et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 36, 337-338 (2004).
-
(2004)
Nat Genet
, vol.36
, pp. 337-338
-
-
Bottini, N.1
-
28
-
-
8744266374
-
The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease
-
Velaga, M.R. et al. The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. J Clin Endocrinol Metab 89, 5862-5865 (2004).
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5862-5865
-
-
Velaga, M.R.1
-
29
-
-
38649125210
-
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
-
Harley, J.B. et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 40, 204-210 (2008).
-
(2008)
Nat Genet
, vol.40
, pp. 204-210
-
-
Harley, J.B.1
-
30
-
-
3242713277
-
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
-
Begovich, A.B. et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 75, 330-337 (2004).
-
(2004)
Am J Hum Genet
, vol.75
, pp. 330-337
-
-
Begovich, A.B.1
-
31
-
-
20544460101
-
HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms
-
Thorsby, E. & Lie, B.A. HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms. Transpl Immunol 14, 175-182 (2005).
-
(2005)
Transpl Immunol
, vol.14
, pp. 175-182
-
-
Thorsby, E.1
Lie, B.A.2
-
32
-
-
36749054721
-
Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases
-
Zhernakova, A. et al. Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases. Am J Hum Genet 81, 1284-1288 (2007).
-
(2007)
Am J Hum Genet
, vol.81
, pp. 1284-1288
-
-
Zhernakova, A.1
-
33
-
-
33747648532
-
Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population
-
Tsurumaru, M. et al. Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population. J Clin Endocrinol Metab 91, 3138-3143 (2006).
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 3138-3143
-
-
Tsurumaru, M.1
-
34
-
-
34347341846
-
Robust associations of four new chromosome regions from genomewide analyses of type 1 diabetes
-
Todd, J.A. et al. Robust associations of four new chromosome regions from genomewide analyses of type 1 diabetes. Nat Genet 39, 857-864 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 857-864
-
-
Todd, J.A.1
-
35
-
-
0038637265
-
Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes
-
Motohashi, Y. et al. Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes. J Clin Endocrinol Metab 88, 3137-3140 (2003).
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3137-3140
-
-
Motohashi, Y.1
-
36
-
-
20944434679
-
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
-
Kochi, Y. et al. A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet 37, 478-485 (2005).
-
(2005)
Nat Genet
, vol.37
, pp. 478-485
-
-
Kochi, Y.1
-
37
-
-
34548427925
-
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
-
Remmers, E.F. et al. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N Engl J Med 357, 977-986 (2007).
-
(2007)
N Engl J Med
, vol.357
, pp. 977-986
-
-
Remmers, E.F.1
-
38
-
-
19244364722
-
Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis
-
Mulcahy, B. et al. Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis. Am J Hum Genet 59, 676-683 (1996).
-
(1996)
Am J Hum Genet
, vol.59
, pp. 676-683
-
-
Mulcahy, B.1
-
39
-
-
0344364566
-
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
-
Tokuhiro, S. et al. An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet 35, 341-348 (2003).
-
(2003)
Nat Genet
, vol.35
, pp. 341-348
-
-
Tokuhiro, S.1
-
40
-
-
0037318784
-
Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis
-
Okamoto, K. et al. Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis. Am J Hum Genet 72, 303-312 (2003).
-
(2003)
Am J Hum Genet
, vol.72
, pp. 303-312
-
-
Okamoto, K.1
-
41
-
-
20944445879
-
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction
-
Swanberg, M. et al. MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction. Nat Genet 37, 486-494 (2005).
-
(2005)
Nat Genet
, vol.37
, pp. 486-494
-
-
Swanberg, M.1
-
42
-
-
33746776902
-
Vitamin Dbinding protein (DBP) gene polymorphism is associated with Graves' disease and the vitamin D status in a Polish population study
-
Kurylowicz, A., Ramos-Lopez, E., Bednarczuk, T. & Badenhoop, K. Vitamin Dbinding protein (DBP) gene polymorphism is associated with Graves' disease and the vitamin D status in a Polish population study. Exp Clin Endocrinol Diabetes 114, 329-335 (2006).
-
(2006)
Exp Clin Endocrinol Diabetes
, vol.114
, pp. 329-335
-
-
Kurylowicz, A.1
Ramos-Lopez, E.2
Bednarczuk, T.3
Badenhoop, K.4
-
43
-
-
3242682494
-
Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene
-
Smerdel, A. et al. Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene. Genes Immun 5, 310-312 (2004).
-
(2004)
Genes Immun
, vol.5
, pp. 310-312
-
-
Smerdel, A.1
-
44
-
-
34547492359
-
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis
-
Sigurdsson, S. et al. Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis. Arthritis Rheum 56, 2202-2210 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2202-2210
-
-
Sigurdsson, S.1
-
45
-
-
34548717681
-
Association of interleukin-1 genetic polymorphisms with the risk of rheumatoid arthritis in Chinese population
-
You, C.G. et al. Association of interleukin-1 genetic polymorphisms with the risk of rheumatoid arthritis in Chinese population. Clin Chem Lab Med 45, 968-971 (2007).
-
(2007)
Clin Chem Lab Med
, vol.45
, pp. 968-971
-
-
You, C.G.1
-
46
-
-
33646510270
-
Interleukin-18 promoter polymorphism in patients with rheumatoid arthritis
-
Pawlik, A. et al. Interleukin-18 promoter polymorphism in patients with rheumatoid arthritis. Tissue Antigens 67, 415-418 (2006).
-
(2006)
Tissue Antigens
, vol.67
, pp. 415-418
-
-
Pawlik, A.1
-
47
-
-
34548351247
-
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis
-
Gregory, S.G. et al. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet 39, 1083-1091 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 1083-1091
-
-
Gregory, S.G.1
-
48
-
-
0041808918
-
Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis
-
Teutsch, S.M., Booth, D.R., Bennetts, B.H., Heard, R.N. & Stewart, G.J. Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis. Eur J Hum Genet 11, 509-515 (2003).
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 509-515
-
-
Teutsch, S.M.1
Booth, D.R.2
Bennetts, B.H.3
Heard, R.N.4
Stewart, G.J.5
-
49
-
-
20144388185
-
Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis
-
Zhang, Z. et al. Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis. Genes Immun 6, 145-152 (2005).
-
(2005)
Genes Immun
, vol.6
, pp. 145-152
-
-
Zhang, Z.1
-
50
-
-
0033662317
-
A point mutation in PTPRC is associated with the development of multiple sclerosis
-
Jacobsen, M. et al. A point mutation in PTPRC is associated with the development of multiple sclerosis. Nat Genet 26, 495-499 (2000).
-
(2000)
Nat Genet
, vol.26
, pp. 495-499
-
-
Jacobsen, M.1
-
51
-
-
10744223574
-
CD24 is a genetic modifier for risk and progression of multiple sclerosis
-
Zhou, Q. et al. CD24 is a genetic modifier for risk and progression of multiple sclerosis. Proc Natl Acad Sci U S A 100, 15041-15046 (2003).
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15041-15046
-
-
Zhou, Q.1
-
52
-
-
0026670087
-
Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene
-
Tienari, P.J., Wikstrom, J., Sajantila, A., Palo, J. & Peltonen, L. Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene. Lancet 340, 987-991 (1992).
-
(1992)
Lancet
, vol.340
, pp. 987-991
-
-
Tienari, P.J.1
Wikstrom, J.2
Sajantila, A.3
Palo, J.4
Peltonen, L.5
-
53
-
-
0001394724
-
CTLA4 promoter and exon 1 dimorphisms in multiple sclerosis
-
Harbo, H.F., Celius, E.G., Vartdal, F. & Spurkland, A. CTLA4 promoter and exon 1 dimorphisms in multiple sclerosis. Tissue Antigens 53, 106-110 (1999).
-
(1999)
Tissue Antigens
, vol.53
, pp. 106-110
-
-
Harbo, H.F.1
Celius, E.G.2
Vartdal, F.3
Spurkland, A.4
-
54
-
-
18044401969
-
The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis
-
Dai, K.Z. et al. The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis. Genes Immun 2, 263-268 (2001).
-
(2001)
Genes Immun
, vol.2
, pp. 263-268
-
-
Dai, K.Z.1
-
55
-
-
0031947049
-
Multiple sclerosis: the increased frequency of the ICAM-1 exon 6 gene point mutation genetic type K469
-
Mycko, M.P., Kwinkowski, M., Tronczynska, E., Szymanska, B. & Selmaj, K.W. Multiple sclerosis: the increased frequency of the ICAM-1 exon 6 gene point mutation genetic type K469. Ann Neurol 44, 70-75 (1998).
-
(1998)
Ann Neurol
, vol.44
, pp. 70-75
-
-
Mycko, M.P.1
Kwinkowski, M.2
Tronczynska, E.3
Szymanska, B.4
Selmaj, K.W.5
-
56
-
-
45249112573
-
Interferon Regulatory Factor 5 (IRF5) Gene Variants are Associated with Multiple Sclerosis in Three Distinct Populations
-
Kristjansdottir, G. et al. Interferon Regulatory Factor 5 (IRF5) Gene Variants are Associated with Multiple Sclerosis in Three Distinct Populations. J Med Genet (2008).
-
(2008)
J Med Genet
-
-
Kristjansdottir, G.1
-
57
-
-
0031911063
-
Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of the TcR beta locus: use of affected family-based controls
-
Hockertz, M.K., Paty, D.W. & Beall, S.S. Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of the TcR beta locus: use of affected family-based controls. Am J Hum Genet 62, 373-385 (1998).
-
(1998)
Am J Hum Genet
, vol.62
, pp. 373-385
-
-
Hockertz, M.K.1
Paty, D.W.2
Beall, S.S.3
-
58
-
-
33645766966
-
PRKCA and multiple sclerosis: association in two independent populations
-
Saarela, J. et al. PRKCA and multiple sclerosis: association in two independent populations. PLoS Genet 2, e42 (2006).
-
(2006)
PLoS Genet
, vol.2
-
-
Saarela, J.1
-
59
-
-
34249860408
-
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
-
Graham, R.R. et al. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A 104, 6758-6763 (2007).
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 6758-6763
-
-
Graham, R.R.1
-
60
-
-
4243900858
-
A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families
-
Gaffney, P.M. et al. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc Natl Acad Sci U S A 95, 14875-14879 (1998).
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14875-14879
-
-
Gaffney, P.M.1
-
61
-
-
17144378972
-
CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis
-
Lee, Y.H., Harley, J.B. & Nath, S.K. CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis. Hum Genet 116, 361-367 (2005).
-
(2005)
Hum Genet
, vol.116
, pp. 361-367
-
-
Lee, Y.H.1
Harley, J.B.2
Nath, S.K.3
-
62
-
-
0029737324
-
Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
-
Wu, J. et al. Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J Clin Invest 98, 1107-1113 (1996).
-
(1996)
J Clin Invest
, vol.98
, pp. 1107-1113
-
-
Wu, J.1
-
63
-
-
0035983742
-
Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility
-
Kyogoku, C. et al. Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility. Arthritis Rheum 46, 1242-1254 (2002).
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1242-1254
-
-
Kyogoku, C.1
-
64
-
-
19544370012
-
Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients
-
Shin, H.D. et al. Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients. Hum Mol Genet 13, 2343-2350 (2004).
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2343-2350
-
-
Shin, H.D.1
-
65
-
-
34548327158
-
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus
-
Lee-Kirsch, M.A. et al. Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat Genet 39, 1065-1067 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 1065-1067
-
-
Lee-Kirsch, M.A.1
-
66
-
-
34247619002
-
A dinucleotide deletion in CD24 confers protection against autoimmune diseases
-
Wang, L. et al. A dinucleotide deletion in CD24 confers protection against autoimmune diseases. PLoS Genet 3, e49 (2007).
-
(2007)
PLoS Genet
, vol.3
-
-
Wang, L.1
-
67
-
-
33744471384
-
A novel single-nucleotide polymorphism of the Fcgamma receptor IIIa gene is associated with genetic susceptibility to systemic lupus erythematosus in Chinese populations: a family-based association study
-
Ye, D. et al. A novel single-nucleotide polymorphism of the Fcgamma receptor IIIa gene is associated with genetic susceptibility to systemic lupus erythematosus in Chinese populations: a family-based association study. Clin Exp Dermatol 31, 553-557 (2006).
-
(2006)
Clin Exp Dermatol
, vol.31
, pp. 553-557
-
-
Ye, D.1
-
68
-
-
40449139904
-
A/C polymorphism in the interleukin-18 coding region among Taiwanese systemic lupus erythematosus patients
-
Lin, Y.J. et al. A/C polymorphism in the interleukin-18 coding region among Taiwanese systemic lupus erythematosus patients. Lupus 17, 124-127 (2008).
-
(2008)
Lupus
, vol.17
, pp. 124-127
-
-
Lin, Y.J.1
-
69
-
-
35748981184
-
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
-
Burton, P.R. et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 39, 1329-1337 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 1329-1337
-
-
Burton, P.R.1
-
70
-
-
35948953900
-
The genetic basis of thyroid autoimmunity
-
Jacobson, E.M. & Tomer, Y. The genetic basis of thyroid autoimmunity. Thyroid 17, 949-961 (2007).
-
(2007)
Thyroid
, vol.17
, pp. 949-961
-
-
Jacobson, E.M.1
Tomer, Y.2
-
71
-
-
0034489819
-
Vitamin D receptor gene polymorphism is associated with Graves' disease in the Japanese population
-
Ban, Y., Taniyama, M. & Ban, Y. Vitamin D receptor gene polymorphism is associated with Graves' disease in the Japanese population. J Clin Endocrinol Metab 85, 4639-4643 (2000).
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4639-4643
-
-
Ban, Y.1
Taniyama, M.2
Ban, Y.3
-
72
-
-
0038368918
-
PDS is a new susceptibility gene to autoimmune thyroid diseases: association and linkage study
-
Hadj Kacem, H. et al. PDS is a new susceptibility gene to autoimmune thyroid diseases: association and linkage study. J Clin Endocrinol Metab 88, 2274-2280 (2003).
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2274-2280
-
-
Hadj Kacem, H.1
-
73
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr, R.H. et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314, 1461-1463 (2006).
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
-
74
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe, J. et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 39, 207-211 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
-
75
-
-
9144224852
-
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease
-
Brant, S.R. et al. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am J Hum Genet 73, 1282-1292 (2003).
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1282-1292
-
-
Brant, S.R.1
-
76
-
-
20544469356
-
TNFalpha and IL10 SNPs act together to predict disease behaviour in Crohn's disease
-
Fowler, E.V. et al. TNFalpha and IL10 SNPs act together to predict disease behaviour in Crohn's disease. J Med Genet 42, 523-528 (2005).
-
(2005)
J Med Genet
, vol.42
, pp. 523-528
-
-
Fowler, E.V.1
-
77
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes, M. et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 39, 830-832 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
-
78
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova, V.D. et al. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat Genet 36, 471-475 (2004).
-
(2004)
Nat Genet
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
-
79
-
-
29744467435
-
MDR1 gene: susceptibility in Spanish Crohn's disease and ulcerative colitis patients
-
Urcelay, E. et al. MDR1 gene: susceptibility in Spanish Crohn's disease and ulcerative colitis patients. Inflamm Bowel Dis 12, 33-37 (2006).
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 33-37
-
-
Urcelay, E.1
-
80
-
-
36249002287
-
An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases
-
Dideberg, V. et al. An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. Hum Mol Genet 16, 3008-3016 (2007).
-
(2007)
Hum Mol Genet
, vol.16
, pp. 3008-3016
-
-
Dideberg, V.1
-
81
-
-
2442519456
-
Genetic variation in DLG5 is associated with inflammatory bowel disease
-
Stoll, M. et al. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat Genet 36, 476-480 (2004).
-
(2004)
Nat Genet
, vol.36
, pp. 476-480
-
-
Stoll, M.1
-
82
-
-
0023663430
-
T cell tolerance by clonal elimination in the thymus
-
Kappler, J.W., Roehm, N. & Marrack, P. T cell tolerance by clonal elimination in the thymus. Cell 49, 273-280 (1987).
-
(1987)
Cell
, vol.49
, pp. 273-280
-
-
Kappler, J.W.1
Roehm, N.2
Marrack, P.3
-
83
-
-
2342458871
-
Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling
-
Epub 2004 Apr 7026
-
Villunger, A. et al. Negative selection of semimature CD4(+)8(-)HSA+ thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling. Proc Natl Acad Sci U S A 101, 7052-7057 Epub 2004 Apr 7026 (2004).
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7052-7057
-
-
Villunger, A.1
-
84
-
-
0037148840
-
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
-
Bouillet, P. et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 415, 922-926. (2002).
-
(2002)
Nature
, vol.415
, pp. 922-926
-
-
Bouillet, P.1
-
85
-
-
0032401760
-
Peripheral-antigen-expressing cells in thymic medulla: factors in selftolerance and autoimmunity
-
Hanahan, D. Peripheral-antigen-expressing cells in thymic medulla: factors in selftolerance and autoimmunity. Curr Opin Immunol 10, 656-662 (1998).
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 656-662
-
-
Hanahan, D.1
-
86
-
-
0036644686
-
Promiscuous gene expression and central T-cell tolerance: more than meets the eye
-
Kyewski, B., Derbinski, J., Gotter, J. & Klein, L. Promiscuous gene expression and central T-cell tolerance: more than meets the eye. Trends Immunol 23, 364-371 (2002).
-
(2002)
Trends Immunol
, vol.23
, pp. 364-371
-
-
Kyewski, B.1
Derbinski, J.2
Gotter, J.3
Klein, L.4
-
87
-
-
0028922437
-
Genetic control of autoimmune diabetes in the NOD mouse
-
Wicker, L.S., Todd, J.A. & Peterson, L.B. Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol 13, 179-200. (1995).
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 179-200
-
-
Wicker, L.S.1
Todd, J.A.2
Peterson, L.B.3
-
88
-
-
0029120178
-
Genetic analysis of experimental allergic encephalomyelitis in mice
-
Baker, D., Rosenwasser, O.A., O'Neill, J.K. & Turk, J.L. Genetic analysis of experimental allergic encephalomyelitis in mice. J Immunol 155, 4046-4051 (1995).
-
(1995)
J Immunol
, vol.155
, pp. 4046-4051
-
-
Baker, D.1
Rosenwasser, O.A.2
O'Neill, J.K.3
Turk, J.L.4
-
89
-
-
0037092957
-
Lethal autoimmune hemolytic anemia in CD47-deficient nonobese diabetic (NOD) mice
-
Oldenborg, P.A., Gresham, H.D., Chen, Y., Izui, S. & Lindberg, F.P. Lethal autoimmune hemolytic anemia in CD47-deficient nonobese diabetic (NOD) mice. Blood 99, 3500-3504 (2002).
-
(2002)
Blood
, vol.99
, pp. 3500-3504
-
-
Oldenborg, P.A.1
Gresham, H.D.2
Chen, Y.3
Izui, S.4
Lindberg, F.P.5
-
90
-
-
0037090305
-
Genetic analysis of autoimmune sialadenitis in nonobese diabetic mice: a major susceptibility region on chromosome 1
-
Boulard, O. et al. Genetic analysis of autoimmune sialadenitis in nonobese diabetic mice: a major susceptibility region on chromosome 1. J Immunol 168, 4192-4201 (2002).
-
(2002)
J Immunol
, vol.168
, pp. 4192-4201
-
-
Boulard, O.1
-
91
-
-
0036236683
-
Autoimmune thyroid disease induced by thyroglobulin and lipopolysaccharide is inhibited by soluble TNF receptor type I
-
Zaccone, P. et al. Autoimmune thyroid disease induced by thyroglobulin and lipopolysaccharide is inhibited by soluble TNF receptor type I. Eur J Immunol 32, 1021-1028 (2002).
-
(2002)
Eur J Immunol
, vol.32
, pp. 1021-1028
-
-
Zaccone, P.1
-
92
-
-
0032957740
-
Spontaneous autoimmune thyroiditis in NOD.H-2h4 mice
-
Braley-Mullen, H., Sharp, G.C., Medling, B. & Tang, H. Spontaneous autoimmune thyroiditis in NOD.H-2h4 mice. J Autoimmun 12, 157-165 (1999).
-
(1999)
J Autoimmun
, vol.12
, pp. 157-165
-
-
Braley-Mullen, H.1
Sharp, G.C.2
Medling, B.3
Tang, H.4
-
93
-
-
0032425571
-
Nonobese diabetic (NOD) mice are genetically susceptible to experimental autoimmune prostatitis (EAP)
-
Rivero, V.E., Cailleau, C., Depiante-Depaoli, M., Riera, C.M. & Carnaud, C. Nonobese diabetic (NOD) mice are genetically susceptible to experimental autoimmune prostatitis (EAP). J Autoimmun 11, 603-610 (1998).
-
(1998)
J Autoimmun
, vol.11
, pp. 603-610
-
-
Rivero, V.E.1
Cailleau, C.2
Depiante-Depaoli, M.3
Riera, C.M.4
Carnaud, C.5
-
94
-
-
0030772630
-
High incidence of autoimmune dacryoadenitis in male nonobese diabetic (NOD) mice depending on sex steroid
-
Takahashi, M. et al. High incidence of autoimmune dacryoadenitis in male nonobese diabetic (NOD) mice depending on sex steroid. Clin Exp Immunol 109, 555-561 (1997).
-
(1997)
Clin Exp Immunol
, vol.109
, pp. 555-561
-
-
Takahashi, M.1
-
95
-
-
0029864145
-
Breaking selftolerance in nonobese diabetic mice
-
Ridgway, W.M., Fasso, M., Lanctot, A., Garvey, C. & Fathman, C.G. Breaking selftolerance in nonobese diabetic mice. J Exp Med 183, 1657-1662. (1996).
-
(1996)
J Exp Med
, vol.183
, pp. 1657-1662
-
-
Ridgway, W.M.1
Fasso, M.2
Lanctot, A.3
Garvey, C.4
Fathman, C.G.5
-
96
-
-
0028139108
-
Mycobacteria precipitate an SLE-like syndrome in diabetes-prone NOD mice
-
Baxter, A.G. et al. Mycobacteria precipitate an SLE-like syndrome in diabetes-prone NOD mice. Immunology 83, 227-231 (1994).
-
(1994)
Immunology
, vol.83
, pp. 227-231
-
-
Baxter, A.G.1
-
97
-
-
0029982537
-
Genetic analysis of autoimmune disease
-
Vyse, T.J. & Todd, J.A. Genetic analysis of autoimmune disease. Cell 85, 311-318 (1996).
-
(1996)
Cell
, vol.85
, pp. 311-318
-
-
Vyse, T.J.1
Todd, J.A.2
-
98
-
-
0035175577
-
A defect in central tolerance in NOD mice
-
Kishimoto, H. & Sprent, J. A defect in central tolerance in NOD mice. Nat Immunol 2, 1025-1031. (2001).
-
(2001)
Nat Immunol
, vol.2
, pp. 1025-1031
-
-
Kishimoto, H.1
Sprent, J.2
-
99
-
-
0037020857
-
Failure to censor forbidden clone of CD4 T cells in autoimmune diabetes
-
Lesage, S. et al. Failure to censor forbidden clone of CD4 T cells in autoimmune diabetes. J Exp Med 196, 1175-1188 (2002).
-
(2002)
J Exp Med
, vol.196
, pp. 1175-1188
-
-
Lesage, S.1
-
100
-
-
4644327995
-
Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC genecontrolled near death experience
-
Choisy-Rossi, C.M., Holl, T.M., Pierce, M.A., Chapman, H.D. & Serreze, D.V. Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC genecontrolled near death experience. J Immunol 173, 3791-3800 (2004).
-
(2004)
J Immunol
, vol.173
, pp. 3791-3800
-
-
Choisy-Rossi, C.M.1
Holl, T.M.2
Pierce, M.A.3
Chapman, H.D.4
Serreze, D.V.5
-
101
-
-
10344231974
-
Generalised resistance to thymic deletion in the NOD mouse: a polygenic trait characterized by defective induction of Bim
-
Liston, A. et al. Generalised resistance to thymic deletion in the NOD mouse: a polygenic trait characterized by defective induction of Bim. Immunity 21, 817-830 (2004).
-
(2004)
Immunity
, vol.21
, pp. 817-830
-
-
Liston, A.1
-
102
-
-
15244338878
-
Defective central tolerance induction in NOD mice: genomics and genetics
-
Zucchelli, S. et al. Defective central tolerance induction in NOD mice: genomics and genetics. Immunity 22, 385-396 (2005).
-
(2005)
Immunity
, vol.22
, pp. 385-396
-
-
Zucchelli, S.1
-
103
-
-
49149106972
-
Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice
-
Serreze, D.V. et al. Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice. J Immunol 180, 3250-3259 (2008).
-
(2008)
J Immunol
, vol.180
, pp. 3250-3259
-
-
Serreze, D.V.1
-
104
-
-
34147128008
-
Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling
-
Liston, A. et al. Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling. Genome Biol 8, R12 (2007).
-
(2007)
Genome Biol
, vol.8
-
-
Liston, A.1
-
105
-
-
33646075180
-
Mutations in the RNA component of RNase mitochondrial RNA processing might cause Omenn syndrome
-
Roifman, C.M., Gu, Y. & Cohen, A. Mutations in the RNA component of RNase mitochondrial RNA processing might cause Omenn syndrome. J Allergy Clin Immunol 117, 897-903 (2006).
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 897-903
-
-
Roifman, C.M.1
Gu, Y.2
Cohen, A.3
-
106
-
-
33344456243
-
Omenn syndrome in an infant with IL7RA gene mutation
-
Giliani, S. et al. Omenn syndrome in an infant with IL7RA gene mutation. J Pediatr 148, 272-274 (2006).
-
(2006)
J Pediatr
, vol.148
, pp. 272-274
-
-
Giliani, S.1
-
107
-
-
34347230543
-
Skin infiltration of CD56(bright) CD16(-) natural killer cells in a case of X-SCID with Omenn syndrome-like manifestations
-
Shibata, F. et al. Skin infiltration of CD56(bright) CD16(-) natural killer cells in a case of X-SCID with Omenn syndrome-like manifestations. Eur J Haematol 79, 81-85 (2007).
-
(2007)
Eur J Haematol
, vol.79
, pp. 81-85
-
-
Shibata, F.1
-
108
-
-
0034501028
-
The genetic and biochemical basis of Omenn syndrome
-
Santagata, S., Villa, A., Sobacchi, C., Cortes, P. & Vezzoni, P. The genetic and biochemical basis of Omenn syndrome. Immunol Rev 178, 64-74 (2000).
-
(2000)
Immunol Rev
, vol.178
, pp. 64-74
-
-
Santagata, S.1
Villa, A.2
Sobacchi, C.3
Cortes, P.4
Vezzoni, P.5
-
109
-
-
0035213341
-
Reviewing Omenn syndrome
-
Aleman, K., Noordzij, J.G., de Groot, R., van Dongen, J.J. & Hartwig, N.G. Reviewing Omenn syndrome. Eur J Pediatr 160, 718-725 (2001).
-
(2001)
Eur J Pediatr
, vol.160
, pp. 718-725
-
-
Aleman, K.1
Noordzij, J.G.2
de Groot, R.3
van Dongen, J.J.4
Hartwig, N.G.5
-
110
-
-
33645785057
-
A severe form of human combined immunodeficiency due to mutations in DNA ligase IV
-
Enders, A. et al. A severe form of human combined immunodeficiency due to mutations in DNA ligase IV. J Immunol 176, 5060-5068 (2006).
-
(2006)
J Immunol
, vol.176
, pp. 5060-5068
-
-
Enders, A.1
-
111
-
-
0035007575
-
Specific immunoglobulin E responses in ZAP-70-deficient patients are mediated by Sykdependent T-cell receptor signalling
-
Toyabe, S., Watanabe, A., Harada, W., Karasawa, T. & Uchiyama, M. Specific immunoglobulin E responses in ZAP-70-deficient patients are mediated by Sykdependent T-cell receptor signalling. Immunology 103, 164-171 (2001).
-
(2001)
Immunology
, vol.103
, pp. 164-171
-
-
Toyabe, S.1
Watanabe, A.2
Harada, W.3
Karasawa, T.4
Uchiyama, M.5
-
112
-
-
0027213371
-
Adult presentation of adenosine deaminase deficiency
-
Shovlin, C.L. et al. Adult presentation of adenosine deaminase deficiency. Lancet 341, 1471 (1993).
-
(1993)
Lancet
, vol.341
, pp. 1471
-
-
Shovlin, C.L.1
-
113
-
-
0027954048
-
Somatic mosaicism for a newly identified splice-site mutation in a patient with adenosine deaminase-deficient immunodeficiency and spontaneous clinical recovery
-
Hirschhorn, R., Yang, D.R., Israni, A., Huie, M.L. & Ownby, D.R. Somatic mosaicism for a newly identified splice-site mutation in a patient with adenosine deaminase-deficient immunodeficiency and spontaneous clinical recovery. Am J Hum Genet 55, 59-68 (1994).
-
(1994)
Am J Hum Genet
, vol.55
, pp. 59-68
-
-
Hirschhorn, R.1
Yang, D.R.2
Israni, A.3
Huie, M.L.4
Ownby, D.R.5
-
114
-
-
0029902033
-
Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency
-
Hirschhorn, R. et al. Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency. Nat Genet 13, 290-295 (1996).
-
(1996)
Nat Genet
, vol.13
, pp. 290-295
-
-
Hirschhorn, R.1
-
115
-
-
34248176213
-
Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model
-
Khiong, K. et al. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest 117, 1270-1281 (2007).
-
(2007)
J Clin Invest
, vol.117
, pp. 1270-1281
-
-
Khiong, K.1
-
116
-
-
34248229621
-
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome
-
Marrella, V. et al. A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome. J Clin Invest 117, 1260-1269 (2007).
-
(2007)
J Clin Invest
, vol.117
, pp. 1260-1269
-
-
Marrella, V.1
-
117
-
-
0345414139
-
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
-
Sakaguchi, N. et al. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice. Nature 426, 454-460 (2003).
-
(2003)
Nature
, vol.426
, pp. 454-460
-
-
Sakaguchi, N.1
-
118
-
-
37049019860
-
Opposing Function of the T Cell Receptor Kinase ZAP-70 in Immunity and Tolerance Differentially Titrate in Response to Nucleotide Substitutions
-
Siggs, O.M. et al. Opposing Function of the T Cell Receptor Kinase ZAP-70 in Immunity and Tolerance Differentially Titrate in Response to Nucleotide Substitutions. Immunity 27, 912-926 (2007).
-
(2007)
Immunity
, vol.27
, pp. 912-926
-
-
Siggs, O.M.1
-
119
-
-
38449096249
-
Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected
-
Venanzi, E.S., Gray, D.H., Benoist, C. & Mathis, D. Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected. J Immunol 179, 5693-5700 (2007).
-
(2007)
J Immunol
, vol.179
, pp. 5693-5700
-
-
Venanzi, E.S.1
Gray, D.H.2
Benoist, C.3
Mathis, D.4
-
120
-
-
14844303460
-
Controlling the thymic microenvironment
-
Gray, D.H. et al. Controlling the thymic microenvironment. Curr Opin Immunol 17, 137-143 (2005).
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 137-143
-
-
Gray, D.H.1
-
121
-
-
40049092383
-
Lymphotoxin receptor is required for the migration and selection of autoreactive T cells in thymic medulla
-
Zhu, M., Chin, R.K., Tumanov, A.V., Liu, X. & Fu, Y.X. Lymphotoxin receptor is required for the migration and selection of autoreactive T cells in thymic medulla. J Immunol 179, 8069-8075 (2007).
-
(2007)
J Immunol
, vol.179
, pp. 8069-8075
-
-
Zhu, M.1
Chin, R.K.2
Tumanov, A.V.3
Liu, X.4
Fu, Y.X.5
-
122
-
-
0034880353
-
DCs and peripheral T cell tolerance
-
Fazekas de St Groth, B. DCs and peripheral T cell tolerance. Semin Immunol 13, 311-322 (2001).
-
(2001)
Semin Immunol
, vol.13
, pp. 311-322
-
-
Fazekas de St Groth, B.1
-
123
-
-
28444469783
-
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-offunction variant
-
Vang, T. et al. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-offunction variant. Nat Genet 37, 1317-1319 (2005).
-
(2005)
Nat Genet
, vol.37
, pp. 1317-1319
-
-
Vang, T.1
-
124
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003).
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
125
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J.D., Gavin, M.A. & Rudensky, A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4, 330-336 (2003).
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
126
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., Cox, T., Yasayko, S.A. & Ramsdell, F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 4, 337-342 (2003).
-
(2003)
Nat Immunol
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
127
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim, J.M., Rasmussen, J.P. & Rudensky, A.Y. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol 8, 191-197 (2007).
-
(2007)
Nat Immunol
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
128
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan, M.S. et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2, 301-306 (2001).
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
-
129
-
-
0036568942
-
Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression
-
Kawahata, K. et al. Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression. J Immunol 168, 4399-4405 (2002).
-
(2002)
J Immunol
, vol.168
, pp. 4399-4405
-
-
Kawahata, K.1
-
130
-
-
0037810672
-
The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens
-
Lohr, J., Knoechel, B., Jiang, S., Sharpe, A.H. & Abbas, A.K. The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens. Nat Immunol 4, 664-669 (2003).
-
(2003)
Nat Immunol
, vol.4
, pp. 664-669
-
-
Lohr, J.1
Knoechel, B.2
Jiang, S.3
Sharpe, A.H.4
Abbas, A.K.5
-
131
-
-
4143066714
-
Recognition of the Peripheral Self by Naturally Arising CD25(+) CD4(+) T Cell Receptors
-
Hsieh, C.S. et al. Recognition of the Peripheral Self by Naturally Arising CD25(+) CD4(+) T Cell Receptors. Immunity 21, 267-277 (2004).
-
(2004)
Immunity
, vol.21
, pp. 267-277
-
-
Hsieh, C.S.1
-
132
-
-
33747099523
-
Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells
-
Pacholczyk, R., Ignatowicz, H., Kraj, P. & Ignatowicz, L. Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells. Immunity 25, 249-259 (2006).
-
(2006)
Immunity
, vol.25
, pp. 249-259
-
-
Pacholczyk, R.1
Ignatowicz, H.2
Kraj, P.3
Ignatowicz, L.4
-
133
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
Kretschmer, K. et al. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol 6, 1219-1227 (2005).
-
(2005)
Nat Immunol
, vol.6
, pp. 1219-1227
-
-
Kretschmer, K.1
-
134
-
-
33644691658
-
On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes
-
Bruder, D. et al. On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes. Diabetes 54, 3395-3401 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 3395-3401
-
-
Bruder, D.1
-
135
-
-
0348223787
-
Conversion of peripheral CD4+CD25-naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen, W. et al. Conversion of peripheral CD4+CD25-naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 198, 1875-1886 (2003).
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
-
136
-
-
4744356110
-
TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25-precursors
-
Fu, S. et al. TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25-precursors. Am J Transplant 4, 1614-1627 (2004).
-
(2004)
Am J Transplant
, vol.4
, pp. 1614-1627
-
-
Fu, S.1
-
137
-
-
2142645808
-
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25-T cells through Foxp3 induction and down-regulation of Smad7
-
Fantini, M.C. et al. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25-T cells through Foxp3 induction and down-regulation of Smad7. J Immunol 172, 5149-5153 (2004).
-
(2004)
J Immunol
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
-
138
-
-
33746379546
-
The role of the transcription factor Foxp3 in the development of regulatory T cells
-
Kim, J.M. & Rudensky, A. The role of the transcription factor Foxp3 in the development of regulatory T cells. Immunol Rev 212, 86-98 (2006).
-
(2006)
Immunol Rev
, vol.212
, pp. 86-98
-
-
Kim, J.M.1
Rudensky, A.2
-
139
-
-
1842480959
-
TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
-
Epub 2004 Mar 4518
-
Peng, Y., Laouar, Y., Li, M.O., Green, E.A. & Flavell, R.A. TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc Natl Acad Sci U S A 101, 4572-4577 Epub 2004 Mar 4518 (2004).
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 4572-4577
-
-
Peng, Y.1
Laouar, Y.2
Li, M.O.3
Green, E.A.4
Flavell, R.A.5
-
140
-
-
4344696770
-
Acquisition of anergic and suppressive activities in transforming growth factor-beta-costimulated CD4+CD25-T cells
-
Epub 2004 Jul 1205
-
Park, H.B., Paik, D.J., Jang, E., Hong, S. & Youn, J. Acquisition of anergic and suppressive activities in transforming growth factor-beta-costimulated CD4+CD25-T cells. Int Immunol 16, 1203-1213 Epub 2004 Jul 1205 (2004).
-
(2004)
Int Immunol
, vol.16
, pp. 1203-1213
-
-
Park, H.B.1
Paik, D.J.2
Jang, E.3
Hong, S.4
Youn, J.5
-
141
-
-
1642410432
-
Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells
-
Verhasselt, V. et al. Induction of FOXP3-expressing regulatory CD4pos T cells by human mature autologous dendritic cells. Eur J Immunol 34, 762-772 (2004).
-
(2004)
Eur J Immunol
, vol.34
, pp. 762-772
-
-
Verhasselt, V.1
-
142
-
-
4043071317
-
Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment
-
Polanczyk, M.J. et al. Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment. J Immunol 173, 2227-2230 (2004).
-
(2004)
J Immunol
, vol.173
, pp. 2227-2230
-
-
Polanczyk, M.J.1
-
143
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Zheng, Y. et al. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 445, 936-940 (2007).
-
(2007)
Nature
, vol.445
, pp. 936-940
-
-
Zheng, Y.1
-
144
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
Gavin, M.A. et al. Foxp3-dependent programme of regulatory T-cell differentiation. Nature (2007).
-
(2007)
Nature
-
-
Gavin, M.A.1
-
145
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams, L.M. & Rudensky, A.Y. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol 8, 277-284 (2007).
-
(2007)
Nat Immunol
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
146
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi, T. et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 10, 1969-1980 (1998).
-
(1998)
Int Immunol
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
-
147
-
-
0028821858
-
Immunopathology of interleukin (IL) 2-deficient mice: thymus dependence and suppression by thymus-dependent cells with an intact IL-2 gene
-
Kramer, S., Schimpl, A. & Hunig, T. Immunopathology of interleukin (IL) 2-deficient mice: thymus dependence and suppression by thymus-dependent cells with an intact IL-2 gene. J Exp Med 182, 1769-1776 (1995).
-
(1995)
J Exp Med
, vol.182
, pp. 1769-1776
-
-
Kramer, S.1
Schimpl, A.2
Hunig, T.3
-
148
-
-
0036839102
-
Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
-
Almeida, A.R., Legrand, N., Papiernik, M. & Freitas, A.A. Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J Immunol 169, 4850-4860 (2002).
-
(2002)
J Immunol
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
149
-
-
0342632839
-
Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo
-
Suzuki, H., Zhou, Y.W., Kato, M., Mak, T.W. & Nakashima, I. Normal regulatory alpha/beta T cells effectively eliminate abnormally activated T cells lacking the interleukin 2 receptor beta in vivo. J Exp Med 190, 1561-1572 (1999).
-
(1999)
J Exp Med
, vol.190
, pp. 1561-1572
-
-
Suzuki, H.1
Zhou, Y.W.2
Kato, M.3
Mak, T.W.4
Nakashima, I.5
-
150
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack, B. et al. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 75, 253-261 (1993).
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
-
151
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
-
Suzuki, H. et al. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science 268, 1472-1476 (1995).
-
(1995)
Science
, vol.268
, pp. 1472-1476
-
-
Suzuki, H.1
-
152
-
-
0028784289
-
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford, D.M. et al. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3, 521-530 (1995).
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
-
153
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot, J.D., Rasmussen, J.P., Gavin, M.A. & Rudensky, A.Y. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol 6, 1142-1151 (2005).
-
(2005)
Nat Immunol
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
154
-
-
34249933446
-
Tracing the action of IL-2 in tolerance to islet-specific antigen
-
Liston, A., Siggs, O.M. & Goodnow, C.C. Tracing the action of IL-2 in tolerance to islet-specific antigen. Immunol Cell Biol 85, 338-342 (2007).
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 338-342
-
-
Liston, A.1
Siggs, O.M.2
Goodnow, C.C.3
-
155
-
-
33646007658
-
Interleukin-2-dependent mechanisms of tolerance and immunity in vivo
-
Antony, P.A. et al. Interleukin-2-dependent mechanisms of tolerance and immunity in vivo. J Immunol 176, 5255-5266 (2006).
-
(2006)
J Immunol
, vol.176
, pp. 5255-5266
-
-
Antony, P.A.1
-
156
-
-
33847246293
-
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
-
Yamanouchi, J. et al. Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. Nat Genet (2007).
-
(2007)
Nat Genet
-
-
Yamanouchi, J.1
-
157
-
-
0033933070
-
Differential glycosylation of interleukin 2, the molecular basis for the NOD Idd3 type 1 diabetes gene?
-
Podolin, P.L. et al. Differential glycosylation of interleukin 2, the molecular basis for the NOD Idd3 type 1 diabetes gene? Cytokine 12, 477-482. (2000).
-
(2000)
Cytokine
, vol.12
, pp. 477-482
-
-
Podolin, P.L.1
-
158
-
-
22544455939
-
CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles
-
Martinez, X. et al. CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles. J Immunol 175, 1677-1685 (2005).
-
(2005)
J Immunol
, vol.175
, pp. 1677-1685
-
-
Martinez, X.1
-
159
-
-
25844504653
-
Developmental regulation of Foxp3 expression during ontogeny
-
Fontenot, J.D., Dooley, J.L., Farr, A.G. & Rudensky, A.Y. Developmental regulation of Foxp3 expression during ontogeny. J Exp Med 202, 901-906 (2005).
-
(2005)
J Exp Med
, vol.202
, pp. 901-906
-
-
Fontenot, J.D.1
Dooley, J.L.2
Farr, A.G.3
Rudensky, A.Y.4
-
160
-
-
16244369437
-
CTLA4 gene polymorphism and autoimmunity
-
Gough, S.C., Walker, L.S. & Sansom, D.M. CTLA4 gene polymorphism and autoimmunity. Immunol Rev 204, 102-115 (2005).
-
(2005)
Immunol Rev
, vol.204
, pp. 102-115
-
-
Gough, S.C.1
Walker, L.S.2
Sansom, D.M.3
-
161
-
-
0029899783
-
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
-
Krummel, M.F. & Allison, J.P. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J Exp Med 183, 2533-2540 (1996).
-
(1996)
J Exp Med
, vol.183
, pp. 2533-2540
-
-
Krummel, M.F.1
Allison, J.P.2
-
162
-
-
0029953858
-
CTLA-4 ligation blocks CD28-dependent T cell activation
-
Walunas, T.L., Bakker, C.Y. & Bluestone, J.A. CTLA-4 ligation blocks CD28-dependent T cell activation. J Exp Med 183, 2541-2550 (1996).
-
(1996)
J Exp Med
, vol.183
, pp. 2541-2550
-
-
Walunas, T.L.1
Bakker, C.Y.2
Bluestone, J.A.3
-
163
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda, H. et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423, 506-511 (2003).
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
-
164
-
-
0033820560
-
NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans
-
Hill, N.J. et al. NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans. Diabetes 49, 1744-1747. (2000).
-
(2000)
Diabetes
, vol.49
, pp. 1744-1747
-
-
Hill, N.J.1
-
165
-
-
0034194611
-
A native soluble form of CTLA-4
-
Oaks, M.K. et al. A native soluble form of CTLA-4. Cell Immunol 201, 144-153 (2000).
-
(2000)
Cell Immunol
, vol.201
, pp. 144-153
-
-
Oaks, M.K.1
-
166
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann, U. et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol 3, 1097-1101 (2002).
-
(2002)
Nat Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
-
167
-
-
38949185084
-
Abatacept: the first T lymphocyte co-stimulation modulator, for the treatment of rheumatoid arthritis
-
Chitale, S. & Moots, R. Abatacept: the first T lymphocyte co-stimulation modulator, for the treatment of rheumatoid arthritis. Expert Opin Biol Ther 8, 115-122 (2008).
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 115-122
-
-
Chitale, S.1
Moots, R.2
-
168
-
-
35748951015
-
IL-10-producing type 1 regulatory T cells and allergy
-
Wu, K., Bi, Y., Sun, K. & Wang, C. IL-10-producing type 1 regulatory T cells and allergy. Cell Mol Immunol 4, 269-275 (2007).
-
(2007)
Cell Mol Immunol
, vol.4
, pp. 269-275
-
-
Wu, K.1
Bi, Y.2
Sun, K.3
Wang, C.4
-
169
-
-
34548131112
-
Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3-precursor cells in the absence of interleukin 10
-
Maynard, C.L. et al. Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3-precursor cells in the absence of interleukin 10. Nat Immunol 8, 931-941 (2007).
-
(2007)
Nat Immunol
, vol.8
, pp. 931-941
-
-
Maynard, C.L.1
-
170
-
-
0030018186
-
T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice
-
Davidson, N.J. et al. T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice. J Exp Med 184, 241-251 (1996).
-
(1996)
J Exp Med
, vol.184
, pp. 241-251
-
-
Davidson, N.J.1
-
171
-
-
41549159660
-
IL-10 produced by regulatory T cells contributes to their suppressor function by limiting inflammation at environmental interfaces
-
Rubtsov, Y.P. et al. IL-10 produced by regulatory T cells contributes to their suppressor function by limiting inflammation at environmental interfaces. Immunity 28, 546-558 (2008).
-
(2008)
Immunity
, vol.28
, pp. 546-558
-
-
Rubtsov, Y.P.1
-
172
-
-
30744458329
-
A case for regulatory B cells
-
Mizoguchi, A. & Bhan, A.K. A case for regulatory B cells. J Immunol 176, 705-710 (2006).
-
(2006)
J Immunol
, vol.176
, pp. 705-710
-
-
Mizoguchi, A.1
Bhan, A.K.2
-
173
-
-
0036795531
-
B cells regulate autoimmunity by provision of IL-10
-
Fillatreau, S., Sweenie, C.H., McGeachy, M.J., Gray, D. & Anderton, S.M. B cells regulate autoimmunity by provision of IL-10. Nat Immunol 3, 944-950 (2002).
-
(2002)
Nat Immunol
, vol.3
, pp. 944-950
-
-
Fillatreau, S.1
Sweenie, C.H.2
McGeachy, M.J.3
Gray, D.4
Anderton, S.M.5
-
174
-
-
0035905471
-
Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis
-
Singh, A.K. et al. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J Exp Med 194, 1801-1811 (2001).
-
(2001)
J Exp Med
, vol.194
, pp. 1801-1811
-
-
Singh, A.K.1
-
175
-
-
0034799397
-
Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
-
Sharif, S. et al. Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat Med 7, 1057-1062 (2001).
-
(2001)
Nat Med
, vol.7
, pp. 1057-1062
-
-
Sharif, S.1
-
176
-
-
0029589931
-
Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4
-
Yoshimoto, T., Bendelac, A., Hu-Li, J. & Paul, W.E. Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4. Proc Natl Acad Sci U S A 92, 11931-11934 (1995).
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11931-11934
-
-
Yoshimoto, T.1
Bendelac, A.2
Hu-Li, J.3
Paul, W.E.4
-
177
-
-
0030615214
-
Association between alphabetaTCR+CD4-CD8-T-cell deficiency and IDDM in NOD/Lt mice
-
Baxter, A.G., Kinder, S.J., Hammond, K.J., Scollay, R. & Godfrey, D.I. Association between alphabetaTCR+CD4-CD8-T-cell deficiency and IDDM in NOD/Lt mice. Diabetes 46, 572-582 (1997).
-
(1997)
Diabetes
, vol.46
, pp. 572-582
-
-
Baxter, A.G.1
Kinder, S.J.2
Hammond, K.J.3
Scollay, R.4
Godfrey, D.I.5
-
178
-
-
0031171897
-
Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8-thymocytes
-
Godfrey, D.I., Kinder, S.J., Silvera, P. & Baxter, A.G. Flow cytometric study of T cell development in NOD mice reveals a deficiency in alphabetaTCR+CDR-CD8-thymocytes. J Autoimmun 10, 279-285. (1997).
-
(1997)
J Autoimmun
, vol.10
, pp. 279-285
-
-
Godfrey, D.I.1
Kinder, S.J.2
Silvera, P.3
Baxter, A.G.4
-
179
-
-
0029825150
-
Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse
-
Gombert, J.M. et al. Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse. Eur J Immunol 26, 2989-2998 (1996).
-
(1996)
Eur J Immunol
, vol.26
, pp. 2989-2998
-
-
Gombert, J.M.1
-
180
-
-
0034928673
-
Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice
-
Poulton, L.D. et al. Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice. Int Immunol 13, 887-896 (2001).
-
(2001)
Int Immunol
, vol.13
, pp. 887-896
-
-
Poulton, L.D.1
-
181
-
-
0042333462
-
Genetic control of NKT cell numbers maps to major diabetes and lupus loci
-
Esteban, L.M. et al. Genetic control of NKT cell numbers maps to major diabetes and lupus loci. J Immunol 171, 2873-2878 (2003).
-
(2003)
J Immunol
, vol.171
, pp. 2873-2878
-
-
Esteban, L.M.1
-
182
-
-
0032489860
-
alpha/beta-T cell receptor (TCR)+CD4-CD8-(NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10
-
Hammond, K.J. et al. alpha/beta-T cell receptor (TCR)+CD4-CD8-(NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10. J Exp Med 187, 1047-1056 (1998).
-
(1998)
J Exp Med
, vol.187
, pp. 1047-1056
-
-
Hammond, K.J.1
-
183
-
-
0032495536
-
Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes
-
Wilson, S.B. et al. Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes. Nature 391, 177-181 (1998).
-
(1998)
Nature
, vol.391
, pp. 177-181
-
-
Wilson, S.B.1
-
184
-
-
39449101603
-
Transcriptional regulation of Th17 cell differentiation
-
Ivanov, II, Zhou, L. & Littman, D.R. Transcriptional regulation of Th17 cell differentiation. Semin Immunol 19, 409-417 (2007).
-
(2007)
Semin Immunol
, vol.19
, pp. 409-417
-
-
Ivanov, I.I.1
Zhou, L.2
Littman, D.R.3
-
185
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae, S., Nambu, A., Sudo, K. & Iwakura, Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 171, 6173-6177 (2003).
-
(2003)
J Immunol
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
186
-
-
33745321276
-
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
-
Komiyama, Y. et al. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol 177, 566-573 (2006).
-
(2006)
J Immunol
, vol.177
, pp. 566-573
-
-
Komiyama, Y.1
-
187
-
-
0033590502
-
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
-
Hutloff, A. et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 397, 263-266 (1999).
-
(1999)
Nature
, vol.397
, pp. 263-266
-
-
Hutloff, A.1
-
188
-
-
0042195831
-
Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses
-
Mak, T.W. et al. Costimulation through the inducible costimulator ligand is essential for both T helper and B cell functions in T cell-dependent B cell responses. Nat Immunol 4, 765-772 (2003).
-
(2003)
Nat Immunol
, vol.4
, pp. 765-772
-
-
Mak, T.W.1
-
189
-
-
0026584291
-
Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
-
Rousset, F. et al. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci U S A 89, 1890-1893 (1992).
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 1890-1893
-
-
Rousset, F.1
-
190
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva, R. et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 448, 480-483 (2007).
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
-
191
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn, T. et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 448, 484-487 (2007).
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
-
192
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou, L. et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 8, 967-974 (2007).
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
-
193
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli, E. et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441, 235-238 (2006).
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
-
194
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan, P.R. et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441, 231-234 (2006).
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
-
195
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov, II et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126, 1121-1133 (2006).
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
-
196
-
-
36248965294
-
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
-
McGeachy, M.J. et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol 8, 1390-1397 (2007).
-
(2007)
Nat Immunol
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
-
197
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C.L. et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201, 233-240 (2005).
-
(2005)
J Exp Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
-
198
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua, D.J. et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421, 744-748 (2003).
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
-
199
-
-
33846608131
-
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
-
Cargill, M. et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 80, 273-290 (2007).
-
(2007)
Am J Hum Genet
, vol.80
, pp. 273-290
-
-
Cargill, M.1
-
200
-
-
21144438325
-
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
-
Vinuesa, C.G. et al. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity. Nature 435, 452-458 (2005).
-
(2005)
Nature
, vol.435
, pp. 452-458
-
-
Vinuesa, C.G.1
-
201
-
-
39749097291
-
Roquin represses autoimmunity by limiting inducible T-cell costimulator messenger RNA
-
Yu, D. et al. Roquin represses autoimmunity by limiting inducible T-cell costimulator messenger RNA. Nature 451, 1022 (2008).
-
(2008)
Nature
, vol.451
, pp. 1022
-
-
Yu, D.1
-
202
-
-
27644452293
-
Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus
-
Cappione, A., 3rd et al. Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus. J Clin Invest 115, 3205-3216 (2005).
-
(2005)
J Clin Invest
, vol.115
, pp. 3205-3216
-
-
Cappione III, A.1
-
203
-
-
5644273872
-
Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus
-
Hutloff, A. et al. Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus. Arthritis Rheum 50, 3211-3220 (2004).
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3211-3220
-
-
Hutloff, A.1
-
204
-
-
38949210228
-
Apoptosis regulators bim and fas function concurrently to control autoimmunity and CD8(+) T cell contraction
-
Weant, A.E. et al. Apoptosis regulators bim and fas function concurrently to control autoimmunity and CD8(+) T cell contraction. Immunity 28, 218-230 (2008).
-
(2008)
Immunity
, vol.28
, pp. 218-230
-
-
Weant, A.E.1
-
205
-
-
38949119408
-
Apoptosis regulators fas and bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity
-
Hughes, P.D. et al. Apoptosis regulators fas and bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity. Immunity 28, 197-205 (2008).
-
(2008)
Immunity
, vol.28
, pp. 197-205
-
-
Hughes, P.D.1
-
206
-
-
38949209522
-
Combined Deficiency of Proapoptotic Regulators Bim and Fas Results in the Early Onset of Systemic Autoimmunity
-
Hutcheson, J. et al. Combined Deficiency of Proapoptotic Regulators Bim and Fas Results in the Early Onset of Systemic Autoimmunity. Immunity 28, 206-217 (2008).
-
(2008)
Immunity
, vol.28
, pp. 206-217
-
-
Hutcheson, J.1
-
207
-
-
0029025441
-
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
-
Fisher, G.H. et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81, 935-946 (1995).
-
(1995)
Cell
, vol.81
, pp. 935-946
-
-
Fisher, G.H.1
-
208
-
-
1942454327
-
Human lupus T cells resist inactivation and escape death by upregulating COX-2
-
Xu, L., Zhang, L., Yi, Y., Kang, H.K. & Datta, S.K. Human lupus T cells resist inactivation and escape death by upregulating COX-2. Nat Med 10, 411-415 (2004).
-
(2004)
Nat Med
, vol.10
, pp. 411-415
-
-
Xu, L.1
Zhang, L.2
Yi, Y.3
Kang, H.K.4
Datta, S.K.5
-
209
-
-
0032528419
-
Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28-T cells from rheumatoid arthritis patients
-
Schirmer, M., Vallejo, A.N., Weyand, C.M. & Goronzy, J.J. Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28-T cells from rheumatoid arthritis patients. J Immunol 161, 1018-1025 (1998).
-
(1998)
J Immunol
, vol.161
, pp. 1018-1025
-
-
Schirmer, M.1
Vallejo, A.N.2
Weyand, C.M.3
Goronzy, J.J.4
-
210
-
-
0035479123
-
Heightened expression of survivin in activated T lymphocytes from patients with multiple sclerosis
-
Sharief, M.K. & Semra, Y.K. Heightened expression of survivin in activated T lymphocytes from patients with multiple sclerosis. J Neuroimmunol 119, 358-364 (2001).
-
(2001)
J Neuroimmunol
, vol.119
, pp. 358-364
-
-
Sharief, M.K.1
Semra, Y.K.2
-
211
-
-
0031018819
-
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
-
Vafiadis, P. et al. Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nat Genet 15, 289-292 (1997).
-
(1997)
Nat Genet
, vol.15
, pp. 289-292
-
-
Vafiadis, P.1
-
212
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
-
Pugliese, A. et al. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nat Genet 15, 293-297 (1997).
-
(1997)
Nat Genet
, vol.15
, pp. 293-297
-
-
Pugliese, A.1
-
213
-
-
34548151158
-
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus
-
Giraud, M. et al. An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus. Nature 448, 934-937 (2007).
-
(2007)
Nature
, vol.448
, pp. 934-937
-
-
Giraud, M.1
-
214
-
-
35748974228
-
Mechanisms of disease: genetics of rheumatoid arthritis--ethnic differences in disease-associated genes
-
Yamada, R. & Yamamoto, K. Mechanisms of disease: genetics of rheumatoid arthritis--ethnic differences in disease-associated genes. Nat Clin Pract Rheumatol 3, 644-650 (2007).
-
(2007)
Nat Clin Pract Rheumatol
, vol.3
, pp. 644-650
-
-
Yamada, R.1
Yamamoto, K.2
-
215
-
-
0028674109
-
The genes influencing the susceptibility to IDDM in humans
-
Faas, S. & Trucco, M. The genes influencing the susceptibility to IDDM in humans. J Endocrinol Invest 17, 477-495 (1994).
-
(1994)
J Endocrinol Invest
, vol.17
, pp. 477-495
-
-
Faas, S.1
Trucco, M.2
-
216
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux, J.D. et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 39, 596-604 (2007).
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
-
217
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
Singh, S.B., Davis, A.S., Taylor, G.A. & Deretic, V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 313, 1438-1441 (2006).
-
(2006)
Science
, vol.313
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
218
-
-
16944367194
-
Positional cloning of the APECED gene
-
Nagamine, K. et al. Positional cloning of the APECED gene. Nat Genet 17, 393-398 (1997).
-
(1997)
Nat Genet
, vol.17
, pp. 393-398
-
-
Nagamine, K.1
-
219
-
-
0346599403
-
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
-
The Finnish-German APECED Consortium
-
The Finnish-German APECED Consortium. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat Genet 17, 399-403 (1997).
-
(1997)
Nat Genet
, vol.17
, pp. 399-403
-
-
-
220
-
-
64549115221
-
Autoimmune polyglandular syndrome type 1
-
Betterle, C., Greggio, N.A. & Volpato, M. Autoimmune polyglandular syndrome type 1. J Clin Endocrinol Metab 83, 1049-1055 (1998).
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 1049-1055
-
-
Betterle, C.1
Greggio, N.A.2
Volpato, M.3
-
221
-
-
0037112047
-
Projection of an Immunological Self-Shadow Within the Thymus by the Aire Protein
-
Anderson, M.S. et al. Projection of an Immunological Self-Shadow Within the Thymus by the Aire Protein. Science 298, 1395-1401 (2002).
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
-
222
-
-
0037084784
-
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
-
Ramsey, C. et al. Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum Mol Genet 11, 397-409. (2002).
-
(2002)
Hum Mol Genet
, vol.11
, pp. 397-409
-
-
Ramsey, C.1
-
223
-
-
0033590981
-
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
-
Heino, M. et al. Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem Biophys Res Commun 257, 821-825. (1999).
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 821-825
-
-
Heino, M.1
-
224
-
-
0036498116
-
Expression of AIRE gene in peripheral monocyte/dendritic cell lineage
-
Kogawa, K. et al. Expression of AIRE gene in peripheral monocyte/dendritic cell lineage. Immunol Lett 80, 195-198 (2002).
-
(2002)
Immunol Lett
, vol.80
, pp. 195-198
-
-
Kogawa, K.1
-
225
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski, J. et al. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med 202, 33-45 (2005).
-
(2005)
J Exp Med
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
-
226
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
Liston, A., Lesage, S., Wilson, J., Peltonen, L. & Goodnow, C.C. Aire regulates negative selection of organ-specific T cells. Nat Immunol 4, 350-354 (2003).
-
(2003)
Nat Immunol
, vol.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
Wilson, J.3
Peltonen, L.4
Goodnow, C.C.5
-
227
-
-
33751513054
-
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen
-
DeVoss, J. et al. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. J Exp Med 203, 2727-2735 (2006).
-
(2006)
J Exp Med
, vol.203
, pp. 2727-2735
-
-
DeVoss, J.1
-
228
-
-
7244227646
-
Gene dosage limiting role of Aire in thymic expression, clonal deletion and organ-specific autoimmunity
-
Liston, A. et al. Gene dosage limiting role of Aire in thymic expression, clonal deletion and organ-specific autoimmunity. J Exp Med 200, 1015-1026 (2004).
-
(2004)
J Exp Med
, vol.200
, pp. 1015-1026
-
-
Liston, A.1
-
229
-
-
0033939699
-
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
-
Heino, M. et al. RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse. Eur J Immunol 30, 1884-1893. (2000).
-
(2000)
Eur J Immunol
, vol.30
, pp. 1884-1893
-
-
Heino, M.1
-
230
-
-
0032924111
-
AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered subcellular distribution of mutants lacking the PHD zinc fingers
-
Rinderle, C., Christensen, H.M., Schweiger, S., Lehrach, H. & Yaspo, M.L. AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered subcellular distribution of mutants lacking the PHD zinc fingers. Hum Mol Genet 8, 277-290 (1999).
-
(1999)
Hum Mol Genet
, vol.8
, pp. 277-290
-
-
Rinderle, C.1
Christensen, H.M.2
Schweiger, S.3
Lehrach, H.4
Yaspo, M.L.5
-
231
-
-
0038824426
-
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein
-
Pitkanen, J. et al. The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein. J Biol Chem 275, 16802-16809. (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 16802-16809
-
-
Pitkanen, J.1
-
232
-
-
0035798665
-
The autoimmune regulator (AIRE) is a DNA-binding protein
-
Kumar, P.G. et al. The autoimmune regulator (AIRE) is a DNA-binding protein. J Biol Chem 276, 41357-41364 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 41357-41364
-
-
Kumar, P.G.1
-
233
-
-
0242536432
-
Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasisectodermal dystrophy protein
-
Bjorses, P. et al. Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasisectodermal dystrophy protein. Am J Hum Genet 66, 378-392. (2000).
-
(2000)
Am J Hum Genet
, vol.66
, pp. 378-392
-
-
Bjorses, P.1
-
234
-
-
34249811200
-
The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function
-
Ruan, Q.G. et al. The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function. J Immunol 178, 7173-7180 (2007).
-
(2007)
J Immunol
, vol.178
, pp. 7173-7180
-
-
Ruan, Q.G.1
-
235
-
-
33646477813
-
Features of medullary thymic epithelium implicate postnatal development in maintaining epithelial heterogeneity and tissue-restricted antigen expression
-
Gillard, G.O. & Farr, A.G. Features of medullary thymic epithelium implicate postnatal development in maintaining epithelial heterogeneity and tissue-restricted antigen expression. J Immunol 176, 5815-5824 (2006).
-
(2006)
J Immunol
, vol.176
, pp. 5815-5824
-
-
Gillard, G.O.1
Farr, A.G.2
-
236
-
-
39149143991
-
Functional interaction of AIRE with PIAS1 in transcriptional regulation
-
Ilmarinen, T. et al. Functional interaction of AIRE with PIAS1 in transcriptional regulation. Mol Immunol 45, 1847-1862 (2008).
-
(2008)
Mol Immunol
, vol.45
, pp. 1847-1862
-
-
Ilmarinen, T.1
-
237
-
-
45849137524
-
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
-
Org, T. et al. The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression. EMBO Rep (2008).
-
(2008)
EMBO Rep
-
-
Org, T.1
-
238
-
-
27944494841
-
AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix
-
Tao, Y. et al. AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix. Mol Immunol 43, 335-345 (2006).
-
(2006)
Mol Immunol
, vol.43
, pp. 335-345
-
-
Tao, Y.1
-
239
-
-
33847350111
-
Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation
-
Gillard, G.O., Dooley, J., Erickson, M., Peltonen, L. & Farr, A.G. Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation. J Immunol 178, 3007-3015 (2007).
-
(2007)
J Immunol
, vol.178
, pp. 3007-3015
-
-
Gillard, G.O.1
Dooley, J.2
Erickson, M.3
Peltonen, L.4
Farr, A.G.5
-
240
-
-
13544262691
-
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
-
Kuroda, N. et al. Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J Immunol 174, 1862-1870 (2005).
-
(2005)
J Immunol
, vol.174
, pp. 1862-1870
-
-
Kuroda, N.1
-
241
-
-
23844558032
-
The cellular mechanism of Aire control of T cell tolerance
-
Anderson, M.S. et al. The cellular mechanism of Aire control of T cell tolerance. Immunity 23, 227-239 (2005).
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
-
242
-
-
36749066715
-
Developmental pathway of CD4+CD8-medullary thymocytes during mouse ontogeny and its defect in Aire-/-mice
-
Li, J. et al. Developmental pathway of CD4+CD8-medullary thymocytes during mouse ontogeny and its defect in Aire-/-mice. Proc Natl Acad Sci U S A 104, 18175-18180 (2007).
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 18175-18180
-
-
Li, J.1
-
243
-
-
18444378139
-
AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype
-
Halonen, M. et al. AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype. J Clin Endocrinol Metab 87, 2568-2574 (2002).
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 2568-2574
-
-
Halonen, M.1
-
244
-
-
0036088555
-
Distinct clinical phenotype and immunoreactivity in Japanese siblings with autoimmune polyglandular syndrome type 1 (APS-1) associated with compound heterozygous novel AIRE gene mutations
-
Kogawa, K. et al. Distinct clinical phenotype and immunoreactivity in Japanese siblings with autoimmune polyglandular syndrome type 1 (APS-1) associated with compound heterozygous novel AIRE gene mutations. Clin Immunol 103, 277-283 (2002).
-
(2002)
Clin Immunol
, vol.103
, pp. 277-283
-
-
Kogawa, K.1
-
245
-
-
25144432460
-
Modifier loci condition autoimmunity provoked by Aire deficiency
-
Jiang, W., Anderson, M.S., Bronson, R., Mathis, D. & Benoist, C. Modifier loci condition autoimmunity provoked by Aire deficiency. J Exp Med 202, 805-815 (2005).
-
(2005)
J Exp Med
, vol.202
, pp. 805-815
-
-
Jiang, W.1
Anderson, M.S.2
Bronson, R.3
Mathis, D.4
Benoist, C.5
-
246
-
-
34548285420
-
Modulation of Aire regulates the expression of tissue-restricted antigens
-
Kont, V. et al. Modulation of Aire regulates the expression of tissue-restricted antigens. Mol Immunol 45, 25-33 (2008).
-
(2008)
Mol Immunol
, vol.45
, pp. 25-33
-
-
Kont, V.1
-
247
-
-
0034610973
-
High frequency of autoreactive myelin proteolipid proteinspecific T cells in the periphery of naive mice: mechanisms of selection of the selfreactive repertoire
-
Anderson, A.C. et al. High frequency of autoreactive myelin proteolipid proteinspecific T cells in the periphery of naive mice: mechanisms of selection of the selfreactive repertoire. J Exp Med 191, 761-770 (2000).
-
(2000)
J Exp Med
, vol.191
, pp. 761-770
-
-
Anderson, A.C.1
-
248
-
-
0037351401
-
Heterozygous null mutation of myelin P0 protein enhances susceptibility to autoimmune neuritis targeting P0 peptide
-
Miyamoto, K., Miyake, S., Schachner, M. & Yamamura, T. Heterozygous null mutation of myelin P0 protein enhances susceptibility to autoimmune neuritis targeting P0 peptide. Eur J Immunol 33, 656-665 (2003).
-
(2003)
Eur J Immunol
, vol.33
, pp. 656-665
-
-
Miyamoto, K.1
Miyake, S.2
Schachner, M.3
Yamamura, T.4
-
249
-
-
34147128054
-
Highly variable expression of tissuerestricted self-antigens in human thymus: implications for self-tolerance and autoimmunity
-
Taubert, R., Schwendemann, J. & Kyewski, B. Highly variable expression of tissuerestricted self-antigens in human thymus: implications for self-tolerance and autoimmunity. Eur J Immunol 37, 838-848 (2007).
-
(2007)
Eur J Immunol
, vol.37
, pp. 838-848
-
-
Taubert, R.1
Schwendemann, J.2
Kyewski, B.3
-
250
-
-
0031878623
-
Iodination of human thyroglobulin (Tg) alters its immunoreactivity. I. Iodination alters multiple epitopes of human Tg
-
Saboori, A.M., Rose, N.R., Bresler, H.S., Vladut-Talor, M. & Burek, C.L. Iodination of human thyroglobulin (Tg) alters its immunoreactivity. I. Iodination alters multiple epitopes of human Tg. Clin Exp Immunol 113, 297-302 (1998).
-
(1998)
Clin Exp Immunol
, vol.113
, pp. 297-302
-
-
Saboori, A.M.1
Rose, N.R.2
Bresler, H.S.3
Vladut-Talor, M.4
Burek, C.L.5
-
251
-
-
27644469005
-
Iodination of murine thyroglobulin enhances autoimmune reactivity in the NOD.H2 mouse
-
Barin, J.G., Talor, M.V., Sharma, R.B., Rose, N.R. & Burek, C.L. Iodination of murine thyroglobulin enhances autoimmune reactivity in the NOD.H2 mouse. Clin Exp Immunol 142, 251-259 (2005).
-
(2005)
Clin Exp Immunol
, vol.142
, pp. 251-259
-
-
Barin, J.G.1
Talor, M.V.2
Sharma, R.B.3
Rose, N.R.4
Burek, C.L.5
-
252
-
-
0031767560
-
Iodine intake and the pattern of thyroid disorders: a comparative epidemiological study of thyroid abnormalities in the elderly in Iceland and in Jutland, Denmark
-
Laurberg, P. et al. Iodine intake and the pattern of thyroid disorders: a comparative epidemiological study of thyroid abnormalities in the elderly in Iceland and in Jutland, Denmark. J Clin Endocrinol Metab 83, 765-769 (1998).
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 765-769
-
-
Laurberg, P.1
-
253
-
-
31044438675
-
HLA, CTLA-4 and PTPN22: the shared genetic master-key to autoimmunity?
-
Brand, O., Gough, S. & Heward, J. HLA, CTLA-4 and PTPN22: the shared genetic master-key to autoimmunity? Expert Reviews in Molecular Medicine 7, 1-15 (2005).
-
(2005)
Expert Reviews in Molecular Medicine
, vol.7
, pp. 1-15
-
-
Brand, O.1
Gough, S.2
Heward, J.3
-
254
-
-
0030827914
-
Major histocompatibility complex-linked control of autoimmunity
-
Wicker, L.S. Major histocompatibility complex-linked control of autoimmunity. J Exp Med 186, 973-975 (1997).
-
(1997)
J Exp Med
, vol.186
, pp. 973-975
-
-
Wicker, L.S.1
-
255
-
-
0034697101
-
A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes
-
Corper, A.L. et al. A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes. Science 288, 505-511 (2000).
-
(2000)
Science
, vol.288
, pp. 505-511
-
-
Corper, A.L.1
-
256
-
-
0034664250
-
The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder
-
Stratmann, T. et al. The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder. J Immunol 165, 3214-3225 (2000).
-
(2000)
J Immunol
, vol.165
, pp. 3214-3225
-
-
Stratmann, T.1
-
257
-
-
0036533658
-
Human DQ8 can substitute for murine I-Ag7 in the selection of diabetogenic T cells restricted to I-Ag7
-
Wen, L., Wong, F.S., Sherwin, R. & Mora, C. Human DQ8 can substitute for murine I-Ag7 in the selection of diabetogenic T cells restricted to I-Ag7. J Immunol 168, 3635-3640 (2002).
-
(2002)
J Immunol
, vol.168
, pp. 3635-3640
-
-
Wen, L.1
Wong, F.S.2
Sherwin, R.3
Mora, C.4
-
258
-
-
26644468528
-
Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule
-
Li, Y. et al. Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule. Embo J 24, 2968-2979 (2005).
-
(2005)
Embo J
, vol.24
, pp. 2968-2979
-
-
Li, Y.1
-
259
-
-
12444298109
-
Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity
-
Maynard, J. et al. Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity. Immunity 22, 81-92 (2005).
-
(2005)
Immunity
, vol.22
, pp. 81-92
-
-
Maynard, J.1
-
260
-
-
31044442026
-
Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritis
-
Burkhardt, H. et al. Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritis. Arthritis Rheum 54, 82-89 (2006).
-
(2006)
Arthritis Rheum
, vol.54
, pp. 82-89
-
-
Burkhardt, H.1
-
261
-
-
4644229910
-
Cutting Edge: Heterozygote Advantage in Autoimmune Disease: Hierarchy of Protection/Susceptibility Conferred by HLA and Killer Ig-Like Receptor Combinations in Psoriatic Arthritis
-
Nelson, G.W. et al. Cutting Edge: Heterozygote Advantage in Autoimmune Disease: Hierarchy of Protection/Susceptibility Conferred by HLA and Killer Ig-Like Receptor Combinations in Psoriatic Arthritis. J Immunol 173, 4273-4276 (2004).
-
(2004)
J Immunol
, vol.173
, pp. 4273-4276
-
-
Nelson, G.W.1
-
262
-
-
33750297701
-
Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility
-
Jones, D.C. et al. Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility. Genes Immun 7, 576 (2006).
-
(2006)
Genes Immun
, vol.7
, pp. 576
-
-
Jones, D.C.1
-
263
-
-
33746885455
-
Neutrophils from p40phox-/-mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing
-
Ellson, C.D. et al. Neutrophils from p40phox-/-mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing. J Exp Med 203, 1927-1937 (2006).
-
(2006)
J Exp Med
, vol.203
, pp. 1927-1937
-
-
Ellson, C.D.1
-
264
-
-
33746896166
-
The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis
-
Suh, C.I. et al. The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med 203, 1915-1925 (2006).
-
(2006)
J Exp Med
, vol.203
, pp. 1915-1925
-
-
Suh, C.I.1
-
265
-
-
33845382786
-
TRPV1(+) sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes
-
Razavi, R. et al. TRPV1(+) sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes. Cell 127, 1123-1135 (2006).
-
(2006)
Cell
, vol.127
, pp. 1123-1135
-
-
Razavi, R.1
-
266
-
-
34248149359
-
Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes
-
Hill, N.J. et al. Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes. Biol Direct 2, 5 (2007).
-
(2007)
Biol Direct
, vol.2
, pp. 5
-
-
Hill, N.J.1
-
267
-
-
0035092748
-
Possible human leukocyte antigen-mediated genetic interaction between type 1 and type 2 Diabetes
-
Li, H. et al. Possible human leukocyte antigen-mediated genetic interaction between type 1 and type 2 Diabetes. J Clin Endocrinol Metab 86, 574-582 (2001).
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 574-582
-
-
Li, H.1
-
268
-
-
0034971563
-
Progress in the characterization of slowly progressive autoimmune diabetes in adult patients (LADA or type 1.5 diabetes)
-
Schernthaner, G. et al. Progress in the characterization of slowly progressive autoimmune diabetes in adult patients (LADA or type 1.5 diabetes). Exp Clin Endocrinol Diabetes 109 Suppl 2, S94-108 (2001).
-
(2001)
Exp Clin Endocrinol Diabetes 109 Suppl
, vol.2
-
-
Schernthaner, G.1
-
269
-
-
33644761984
-
Is latent autoimmune diabetes in adults distinct from type 1 diabetes or just type 1 diabetes at an older age?
-
Palmer, J.P., Hampe, C.S., Chiu, H., Goel, A. & Brooks-Worrell, B.M. Is latent autoimmune diabetes in adults distinct from type 1 diabetes or just type 1 diabetes at an older age? Diabetes 54 Suppl 2, S62-67 (2005).
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Palmer, J.P.1
Hampe, C.S.2
Chiu, H.3
Goel, A.4
Brooks-Worrell, B.M.5
-
270
-
-
0031560175
-
UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group
-
Turner, R. et al. UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group. Lancet 350, 1288-1293 (1997).
-
(1997)
Lancet
, vol.350
, pp. 1288-1293
-
-
Turner, R.1
-
271
-
-
34447119407
-
Genetics of gestational diabetes mellitus and type 2 diabetes
-
Watanabe, R.M. et al. Genetics of gestational diabetes mellitus and type 2 diabetes. Diabetes Care 30 Suppl 2, S134-140 (2007).
-
(2007)
Diabetes Care 30 Suppl
, vol.2
-
-
Watanabe, R.M.1
-
272
-
-
0023223422
-
Familial diabetes aggregation in type I diabetics: gestational diabetes an apparent risk factor for increased diabetes susceptibility in the offspring
-
Dorner, G., Plagemann, A. & Reinagel, H. Familial diabetes aggregation in type I diabetics: gestational diabetes an apparent risk factor for increased diabetes susceptibility in the offspring. Exp Clin Endocrinol 89, 84-90 (1987).
-
(1987)
Exp Clin Endocrinol
, vol.89
, pp. 84-90
-
-
Dorner, G.1
Plagemann, A.2
Reinagel, H.3
-
273
-
-
0029067619
-
Prevalence of diabetes mellitus and impaired glucose tolerance in parents of women with gestational diabetes
-
McLellan, J.A. et al. Prevalence of diabetes mellitus and impaired glucose tolerance in parents of women with gestational diabetes. Diabetologia 38, 693-698 (1995).
-
(1995)
Diabetologia
, vol.38
, pp. 693-698
-
-
McLellan, J.A.1
-
274
-
-
0021997016
-
Frequency of diabetes mellitus in mothers of probands with gestational diabetes: possible maternal influence on the predisposition to gestational diabetes
-
Martin, A.O., Simpson, J.L., Ober, C. & Freinkel, N. Frequency of diabetes mellitus in mothers of probands with gestational diabetes: possible maternal influence on the predisposition to gestational diabetes. Am J Obstet Gynecol 151, 471-475 (1985).
-
(1985)
Am J Obstet Gynecol
, vol.151
, pp. 471-475
-
-
Martin, A.O.1
Simpson, J.L.2
Ober, C.3
Freinkel, N.4
-
275
-
-
0141446269
-
Testing the accelerator hypothesis: the relationship between body mass and age at diagnosis of type 1 diabetes
-
Kibirige, M., Metcalf, B., Renuka, R. & Wilkin, T.J. Testing the accelerator hypothesis: the relationship between body mass and age at diagnosis of type 1 diabetes. Diabetes Care 26, 2865-2870 (2003).
-
(2003)
Diabetes Care
, vol.26
, pp. 2865-2870
-
-
Kibirige, M.1
Metcalf, B.2
Renuka, R.3
Wilkin, T.J.4
-
276
-
-
33644790167
-
Association of the TSHR gene with Graves' disease: the first disease specific locus
-
Dechairo, B.M. et al. Association of the TSHR gene with Graves' disease: the first disease specific locus. Eur J Hum Genet 13, 1223-1230 (2005).
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 1223-1230
-
-
Dechairo, B.M.1
-
277
-
-
0028820361
-
A 138-nucleotide deletion in the thyroglobulin ribonucleic acid messenger in a congenital goiter with defective thyroglobulin synthesis
-
Targovnik, H.M. et al. A 138-nucleotide deletion in the thyroglobulin ribonucleic acid messenger in a congenital goiter with defective thyroglobulin synthesis. J Clin Endocrinol Metab 80, 3356-3360 (1995).
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3356-3360
-
-
Targovnik, H.M.1
-
278
-
-
0029973239
-
A neomutation of the thyroid-stimulating hormone receptor in a severe neonatal hyperthyroidism
-
de Roux, N. et al. A neomutation of the thyroid-stimulating hormone receptor in a severe neonatal hyperthyroidism. J Clin Endocrinol Metab 81, 2023-2026 (1996).
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 2023-2026
-
-
de Roux, N.1
|