An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

Nature Genetics

Volumn 35, Issue 4, 2003, Pages 341-348

  Tokuhiro, Shinya ^a,b   Yamada, Ryo ^a   Chang, Xiaotian ^a   Suzuki, Akari ^a   Kochi, Yuta ^a,c   Sawada, Tetsuji ^c   Suzuki, Masakatsu ^b   Nagasaki, Miyuki ^b   Ohtsuki, Masahiko ^b   Ono, Mitsuru ^b   Furukawa, Hidehiko ^b   Nagashima, Masakazu ^d   Yoshino, Shinichi ^d   Mabuchi, Akihiko ^a   Sekine, Akihiro ^a   Saito, Susumu ^a   Takahashi, Atsushi ^a   Tsunoda, Tatsuhiko ^a   Nakamura, Yusuke ^a,e   Yamamoto, Kazuhiko ^a,c  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^b Sankyo Research Institute   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NIPPON MEDICAL SCHOOL   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

M PROTEIN; PROTEIN SLC22A4; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BINDING AFFINITY; CATION TRANSPORT; CHROMOSOME 5Q; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; JAPAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION REGULATION;

ANIMALS; ARTHRITIS, RHEUMATOID; CARRIER PROTEINS; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 5; COLLAGEN; CORE BINDING FACTOR ALPHA 2 SUBUNIT; CYTOKINES; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRONS; JURKAT CELLS; LINKAGE DISEQUILIBRIUM; LUCIFERASES; MALE; MEMBRANE PROTEINS; MICE; MIDDLE AGED; ORGANIC ANION TRANSPORTERS; ORGANIC CATION TRANSPORT PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS;

EID: 0344364566     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1267     Document Type: Article

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