-
1
-
-
2442567829
-
Back to central tolerance
-
Mathis, D. & Benoist, C. Back to central tolerance. Immunity 20, 509-516 (2004).
-
(2004)
Immunity
, vol.20
, pp. 509-516
-
-
Mathis, D.1
Benoist, C.2
-
2
-
-
16244418695
-
Genetic lesions in T-cell tolerance and thresholds for autoimmunity
-
Liston, A., Lesage, S., Gray, D. H., Boyd, R. L. & Goodnow, C. C. Genetic lesions in T-cell tolerance and thresholds for autoimmunity. Immunol. Rev. 204, 87-101 (2005).
-
(2005)
Immunol. Rev
, vol.204
, pp. 87-101
-
-
Liston, A.1
Lesage, S.2
Gray, D.H.3
Boyd, R.L.4
Goodnow, C.C.5
-
3
-
-
33646165128
-
A central role for central tolerance
-
Kyewski, B. & Klein, L. A central role for central tolerance. Annu. Rev. Immunol. 24, 571-606 (2006).
-
(2006)
Annu. Rev. Immunol
, vol.24
, pp. 571-606
-
-
Kyewski, B.1
Klein, L.2
-
4
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the Aire protein
-
Anderson, M. S. et al. Projection of an immunological self shadow within the thymus by the Aire protein. Science 298, 1395-1401 (2002).
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
-
5
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski, J. et al. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J. Exp. Med. 202, 33-45 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
-
6
-
-
16944367194
-
Positional cloning of the APECED gene
-
Nagamine, K. et al. Positional cloning of the APECED gene. Nature Genet. 17, 393-398 (1997).
-
(1997)
Nature Genet
, vol.17
, pp. 393-398
-
-
Nagamine, K.1
-
7
-
-
0346599403
-
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
-
The Finnish-German APECED Consortium
-
The Finnish-German APECED Consortium. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nature Genet. 17, 399-403 (1997).
-
(1997)
Nature Genet
, vol.17
, pp. 399-403
-
-
-
8
-
-
0028779203
-
Myasthenia gravis
-
Drachman, D. B. Myasthenia gravis. N. Engl. J. Med. 330, 1797-1810 (1994).
-
(1994)
N. Engl. J. Med
, vol.330
, pp. 1797-1810
-
-
Drachman, D.B.1
-
9
-
-
0036779688
-
Unravelling the pathogenesis of myasthenia gravis
-
Vincent, A. Unravelling the pathogenesis of myasthenia gravis. Nature Rev. Immunol. 2, 797-804 (2002).
-
(2002)
Nature Rev. Immunol
, vol.2
, pp. 797-804
-
-
Vincent, A.1
-
10
-
-
24744458604
-
Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages
-
Tamura, T., Thotakura, P., Tanaka, T. S., Ko, M. S. & Ozato, K. Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages. Blood 106, 1938-1947 (2005).
-
(2005)
Blood
, vol.106
, pp. 1938-1947
-
-
Tamura, T.1
Thotakura, P.2
Tanaka, T.S.3
Ko, M.S.4
Ozato, K.5
-
11
-
-
0036181161
-
On the role of IRF in host defense
-
Barnes, B., Lubyova, B. & Pitha, P. M. On the role of IRF in host defense. J. Interferon Cytokine Res. 22, 59-71 (2002).
-
(2002)
J. Interferon Cytokine Res
, vol.22
, pp. 59-71
-
-
Barnes, B.1
Lubyova, B.2
Pitha, P.M.3
-
12
-
-
13444283466
-
Roles of interferon-regulatory factors in T-helper-cell differentiation
-
Lohoff, M. & Mak, T. W. Roles of interferon-regulatory factors in T-helper-cell differentiation. Nature Rev. Immunol. 5, 125-135 (2005).
-
(2005)
Nature Rev. Immunol
, vol.5
, pp. 125-135
-
-
Lohoff, M.1
Mak, T.W.2
-
13
-
-
16044369709
-
Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
-
Holtschke, T. et al. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 87, 307-317 (1996).
-
(1996)
Cell
, vol.87
, pp. 307-317
-
-
Holtschke, T.1
-
14
-
-
0036544858
-
A new type of mutation causes a splicing defect in ATM
-
Pagani, F. et al. A new type of mutation causes a splicing defect in ATM. Nature Genet. 30, 426-429 (2002).
-
(2002)
Nature Genet
, vol.30
, pp. 426-429
-
-
Pagani, F.1
-
15
-
-
0028246975
-
Establishment and characterization of cloned human thymic epithelial cell lines. Analysis of adhesion molecule expression and cytokine production
-
Fernandez, E. et al. Establishment and characterization of cloned human thymic epithelial cell lines. Analysis of adhesion molecule expression and cytokine production. Blood 83, 3245-3254 (1994).
-
(1994)
Blood
, vol.83
, pp. 3245-3254
-
-
Fernandez, E.1
-
16
-
-
4544258485
-
Self-representation in the thymus: An extended view
-
Kyewski, B. & Derbinski, J. Self-representation in the thymus: an extended view. Nature Rev. Immunol. 4, 688-698 (2004).
-
(2004)
Nature Rev. Immunol
, vol.4
, pp. 688-698
-
-
Kyewski, B.1
Derbinski, J.2
-
17
-
-
5144231380
-
Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage
-
Sillanpaa, N. et al. Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage. Mol. Immunol. 41, 1185-1198 (2004).
-
(2004)
Mol. Immunol
, vol.41
, pp. 1185-1198
-
-
Sillanpaa, N.1
-
18
-
-
20744433548
-
Cooperative activation of transcription by autoimmune regulator AIRE and CBP
-
Pitkanen, J. et al. Cooperative activation of transcription by autoimmune regulator AIRE and CBP. Biochem. Biophys. Res. Commun. 333, 944-953 (2005).
-
(2005)
Biochem. Biophys. Res. Commun
, vol.333
, pp. 944-953
-
-
Pitkanen, J.1
-
19
-
-
0031018819
-
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
-
Vafiadis, P. et al. Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nature Genet. 15, 289-292 (1997).
-
(1997)
Nature Genet
, vol.15
, pp. 289-292
-
-
Vafiadis, P.1
-
20
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
-
Pugliese, A. et al. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nature Genet. 15, 293-297 (1997).
-
(1997)
Nature Genet
, vol.15
, pp. 293-297
-
-
Pugliese, A.1
-
21
-
-
27844563909
-
Insulin alleles and autoimmune regulator (AIRE) gene expression both influence insulin expression in the thymus
-
Sabater, L. et al. Insulin alleles and autoimmune regulator (AIRE) gene expression both influence insulin expression in the thymus. J. Autoimmun. 25, 312-318 (2005).
-
(2005)
J. Autoimmun
, vol.25
, pp. 312-318
-
-
Sabater, L.1
-
22
-
-
34147128054
-
Highly variable expression of tissue-restricted self-antigens in human thymus: Implications for self-tolerance and autoimmunity
-
Taubert, R., Schwendemann, J. & Kyewski, B. Highly variable expression of tissue-restricted self-antigens in human thymus: implications for self-tolerance and autoimmunity. Eur. J. Immunol. 37, 838-848 (2007).
-
(2007)
Eur. J. Immunol
, vol.37
, pp. 838-848
-
-
Taubert, R.1
Schwendemann, J.2
Kyewski, B.3
-
23
-
-
0036315824
-
Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: The mechanism by which the IDDM2 locus may predispose to diabetes
-
Chentoufi, A. A. & Polychronakos, C. Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes. Diabetes 51, 1383-1390 (2002).
-
(2002)
Diabetes
, vol.51
, pp. 1383-1390
-
-
Chentoufi, A.A.1
Polychronakos, C.2
-
24
-
-
85047689216
-
Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice
-
Thebault-Baumont, K. et al. Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice. J. Clin. Invest. 111, 851-857 (2003).
-
(2003)
J. Clin. Invest
, vol.111
, pp. 851-857
-
-
Thebault-Baumont, K.1
-
25
-
-
7244227646
-
Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
-
Liston, A. et al. Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J. Exp. Med. 200, 1015-1026 (2004).
-
(2004)
J. Exp. Med
, vol.200
, pp. 1015-1026
-
-
Liston, A.1
-
26
-
-
0031955518
-
Base-calling of automated sequencer traces using phred. I. Accuracy assessment
-
Ewing, B., Hillier, L., Wendl, M. C. & Green, P. Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8, 175-185 (1998).
-
(1998)
Genome Res
, vol.8
, pp. 175-185
-
-
Ewing, B.1
Hillier, L.2
Wendl, M.C.3
Green, P.4
-
27
-
-
0346373654
-
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
-
Carlson, C. S. et al. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am. J. Hum. Genet. 74, 106-120 (2004).
-
(2004)
Am. J. Hum. Genet
, vol.74
, pp. 106-120
-
-
Carlson, C.S.1
-
28
-
-
0942288397
-
Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
-
Gotter, J., Brors, B., Hergenhahn, M. & Kyewski, B. Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J. Exp. Med. 199, 155-166 (2004).
-
(2004)
J. Exp. Med
, vol.199
, pp. 155-166
-
-
Gotter, J.1
Brors, B.2
Hergenhahn, M.3
Kyewski, B.4
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