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Volumn 23, Issue 2, 2005, Pages 227-239

The cellular mechanism of Aire control of T cell tolerance

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; CELL ACTIVITY; CELL DIFFERENTIATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE CONTROL; GENE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STROMA; T LYMPHOCYTE; THYMOCYTE;

EID: 23844558032     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.07.005     Document Type: Article
Times cited : (529)

References (43)
  • 2
    • 0028108177 scopus 로고
    • Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion
    • M.J. Barnden, W.R. Heath, S. Rodda, and F.R. Carbone Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion Eur. J. Immunol. 24 1994 2452 2456
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2452-2456
    • Barnden, M.J.1    Heath, W.R.2    Rodda, S.3    Carbone, F.R.4
  • 3
    • 0037450727 scopus 로고    scopus 로고
    • T cell regulation as a side effect of homeostasis and competition
    • T. Barthlott, G. Kassiotis, and B. Stockinger T cell regulation as a side effect of homeostasis and competition J. Exp. Med. 197 2003 451 460
    • (2003) J. Exp. Med. , vol.197 , pp. 451-460
    • Barthlott, T.1    Kassiotis, G.2    Stockinger, B.3
  • 4
    • 15744397285 scopus 로고    scopus 로고
    • NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease
    • M.J. Bottomley, G. Stier, D. Pennacchini, G. Legube, B. Simon, A. Akhtar, M. Sattler, and G. Musco NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy- candidiasis-ectodermal dystrophy (APECED) disease J. Biol. Chem. 280 2005 11505 11512
    • (2005) J. Biol. Chem. , vol.280 , pp. 11505-11512
    • Bottomley, M.J.1    Stier, G.2    Pennacchini, D.3    Legube, G.4    Simon, B.5    Akhtar, A.6    Sattler, M.7    Musco, G.8
  • 6
    • 0036467491 scopus 로고    scopus 로고
    • HLA-DM, HLA-DO and tapasin: Functional similarities and differences
    • P. Brocke, N. Garbi, F. Momburg, and G.J. Hammerling HLA-DM, HLA-DO and tapasin: functional similarities and differences Curr. Opin. Immunol. 14 2002 22 29
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 22-29
    • Brocke, P.1    Garbi, N.2    Momburg, F.3    Hammerling, G.J.4
  • 7
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • J. Derbinski, A. Schulte, B. Kyewski, and L. Klein Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self Nat. Immunol. 2 2001 1032 1039
    • (2001) Nat. Immunol. , vol.2 , pp. 1032-1039
    • Derbinski, J.1    Schulte, A.2    Kyewski, B.3    Klein, L.4
  • 8
    • 0034541174 scopus 로고    scopus 로고
    • The TNF receptor family member CD30 is not essential for negative selection
    • A.L. DeYoung, O. Duramad, and A. Winoto The TNF receptor family member CD30 is not essential for negative selection J. Immunol. 165 2000 6170 6173
    • (2000) J. Immunol. , vol.165 , pp. 6170-6173
    • Deyoung, A.L.1    Duramad, O.2    Winoto, A.3
  • 9
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • J.D. Fontenot, M.A. Gavin, and A.Y. Rudensky Foxp3 programs the development and function of CD4+CD25+ regulatory T cells Nat. Immunol. 4 2003 330 336
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 11
    • 7244227645 scopus 로고    scopus 로고
    • Central Tolerance to Tissue-specific Antigens Mediated by Direct and Indirect Antigen Presentation
    • A.M. Gallegos, and M.J. Bevan Central Tolerance to Tissue-specific Antigens Mediated by Direct and Indirect Antigen Presentation J. Exp. Med. 200 2004 1039 1049
    • (2004) J. Exp. Med. , vol.200 , pp. 1039-1049
    • Gallegos, A.M.1    Bevan, M.J.2
  • 12
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 2003 1057 1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 14
    • 0028301977 scopus 로고
    • T-cell tolerance toward a transgenic β-cell antigen and transcription of endogenous pancreatic genes in thymus
    • C. Jolicoeur, D. Hanahan, and K.M. Smith T-cell tolerance toward a transgenic β-cell antigen and transcription of endogenous pancreatic genes in thymus Proc. Natl. Acad. Sci. USA 91 1994 6707 6711
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6707-6711
    • Jolicoeur, C.1    Hanahan, D.2    Smith, K.M.3
  • 15
    • 0346996879 scopus 로고    scopus 로고
    • The regulatory T cell family: Distinct subsets and their interrelations
    • H. Jonuleit, and E. Schmitt The regulatory T cell family: distinct subsets and their interrelations J. Immunol. 171 2003 6323 6327
    • (2003) J. Immunol. , vol.171 , pp. 6323-6327
    • Jonuleit, H.1    Schmitt, E.2
  • 17
    • 0023900635 scopus 로고
    • Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
    • P. Kisielow, H. Bluthmann, U.D. Staerz, M. Steinmetz, and H. von Boehmer Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes Nature 333 1988 742 746
    • (1988) Nature , vol.333 , pp. 742-746
    • Kisielow, P.1    Bluthmann, H.2    Staerz, U.D.3    Steinmetz, M.4    Von Boehmer, H.5
  • 18
    • 0023683669 scopus 로고
    • Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
    • P. Kisielow, H.S. Teh, H. Bluthmann, and H. von Boehmer Positive selection of antigen-specific T cells in thymus by restricting MHC molecules Nature 335 1988 730 733
    • (1988) Nature , vol.335 , pp. 730-733
    • Kisielow, P.1    Teh, H.S.2    Bluthmann, H.3    Von Boehmer, H.4
  • 19
    • 0032490563 scopus 로고    scopus 로고
    • CD4 T cell tolerance to human c-reative protein, an inducible serum protein, is mediated by medullary thymic epithelium
    • L. Klein, T. Klein, U. Ruther, and B. Kyewski CD4 T cell tolerance to human c-reative protein, an inducible serum protein, is mediated by medullary thymic epithelium J. Exp. Med. 188 1998 5 16
    • (1998) J. Exp. Med. , vol.188 , pp. 5-16
    • Klein, L.1    Klein, T.2    Ruther, U.3    Kyewski, B.4
  • 21
    • 0029812040 scopus 로고    scopus 로고
    • Constitutive class I-restricted exogenous presentation of self antigens in vivo
    • C. Kurts, W.R. Heath, F.R. Carbone, J. Allison, J.F. Miller, and H. Kosaka Constitutive class I-restricted exogenous presentation of self antigens in vivo J. Exp. Med. 184 1996 923 930
    • (1996) J. Exp. Med. , vol.184 , pp. 923-930
    • Kurts, C.1    Heath, W.R.2    Carbone, F.R.3    Allison, J.4    Miller, J.F.5    Kosaka, H.6
  • 22
    • 1642289268 scopus 로고    scopus 로고
    • CCR7 directs the migration of thymocytes into the thymic medulla
    • J. Kwan, and N. Killeen CCR7 directs the migration of thymocytes into the thymic medulla J. Immunol. 172 2004 3999 4007
    • (2004) J. Immunol. , vol.172 , pp. 3999-4007
    • Kwan, J.1    Killeen, N.2
  • 23
    • 0036644686 scopus 로고    scopus 로고
    • Promiscuous gene expression and central T-cell tolerance: More than meets the eye
    • B. Kyewski, J. Derbinski, J. Gotter, and L. Klein Promiscuous gene expression and central T-cell tolerance: more than meets the eye Trends Immunol. 23 2002 364 371
    • (2002) Trends Immunol. , vol.23 , pp. 364-371
    • Kyewski, B.1    Derbinski, J.2    Gotter, J.3    Klein, L.4
  • 27
    • 2442567829 scopus 로고    scopus 로고
    • Back to central tolerance
    • D. Mathis, and C. Benoist Back to central tolerance Immunity 20 2004 509 516
    • (2004) Immunity , vol.20 , pp. 509-516
    • Mathis, D.1    Benoist, C.2
  • 28
    • 0024571804 scopus 로고
    • Does T-cell tolerance require a dedicated antigen-presenting cell?
    • P. Matzinger, and S. Guerder Does T-cell tolerance require a dedicated antigen-presenting cell? Nature 338 1989 74 76
    • (1989) Nature , vol.338 , pp. 74-76
    • Matzinger, P.1    Guerder, S.2
  • 30
  • 32
    • 0242491039 scopus 로고    scopus 로고
    • Negative selection and autoimmunity
    • P.S. Ohashi Negative selection and autoimmunity Curr. Opin. Immunol. 15 2003 668 676
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 668-676
    • Ohashi, P.S.1
  • 33
    • 9744262548 scopus 로고    scopus 로고
    • Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery
    • K.M. Paulsson Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery Cell. Mol. Life Sci. 61 2004 2446 2460
    • (2004) Cell. Mol. Life Sci. , vol.61 , pp. 2446-2460
    • Paulsson, K.M.1
  • 35
    • 0030849637 scopus 로고    scopus 로고
    • Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
    • R. Rooke, C. Waltzinger, C. Benoist, and D. Mathis Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses Immunity 7 1997 123 134
    • (1997) Immunity , vol.7 , pp. 123-134
    • Rooke, R.1    Waltzinger, C.2    Benoist, C.3    Mathis, D.4
  • 36
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • S. Sakaguchi Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses Annu. Rev. Immunol. 22 2004 531 562
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 37
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, and M. Toda Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases J. Immunol. 155 1995 1151 1164
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 38
    • 0030796631 scopus 로고    scopus 로고
    • Pancreatic gene expression in rare cells of thymic medulla: Evidence for functional contribution to T cell tolerance
    • K.M. Smith, D.C. Olson, R. Hirose, and D. Hanahan Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance Int. Immunol. 9 1997 1355 1365
    • (1997) Int. Immunol. , vol.9 , pp. 1355-1365
    • Smith, K.M.1    Olson, D.C.2    Hirose, R.3    Hanahan, D.4
  • 40
    • 9244244736 scopus 로고    scopus 로고
    • Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells
    • H.M. van Santen, C. Benoist, and D. Mathis Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells J. Exp. Med. 200 2004 1221 1230
    • (2004) J. Exp. Med. , vol.200 , pp. 1221-1230
    • Van Santen, H.M.1    Benoist, C.2    Mathis, D.3
  • 41
    • 0036360019 scopus 로고    scopus 로고
    • The enemy within: Keeping self-reactive T cells at bay in the periphery
    • L.S. Walker, and A.K. Abbas The enemy within: keeping self-reactive T cells at bay in the periphery Nat. Rev. Immunol. 2 2002 11 19
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 11-19
    • Walker, L.S.1    Abbas, A.K.2
  • 42
    • 14244259515 scopus 로고    scopus 로고
    • Directed migration of positively selected thymocytes visualized in real time
    • 10.1371/journal.pbio.0030160
    • C.M. Witt, S. Raychaudhuri, B. Schaefer, A.K. Chakraborty, and E.A. Robey Directed migration of positively selected thymocytes visualized in real time PLoS Biol. 3 2005 e160 10.1371/journal.pbio.0030160
    • (2005) PLoS Biol. , vol.3 , pp. 160
    • Witt, C.M.1    Raychaudhuri, S.2    Schaefer, B.3    Chakraborty, A.K.4    Robey, E.A.5
  • 43
    • 71749101705 scopus 로고    scopus 로고
    • Sex differences in sex chromosome gene expression in mouse brain
    • J. Xu, P.S. Burgoyne, and A.P. Arnold Sex differences in sex chromosome gene expression in mouse brain Hum. Mol. Genet. 11 2002 1409 1419
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1409-1419
    • Xu, J.1    Burgoyne, P.S.2    Arnold, A.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.