Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing

Journal of Experimental Medicine

Volumn 203, Issue 8, 2006, Pages 1927-1937

  Ellson, Chris D ^a   Davidson, Keith ^a   Ferguson, G John ^a   O'Connor, Rod ^a   Stephens, Len R ^a   Hawkins, Phillip T ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; FIBRINOGEN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; PROTEIN P22; PROTEIN P22PHOX; PROTEIN P40; PROTEIN P40PHOX; PROTEIN P47; PROTEIN P47PHOX; PROTEIN P67; PROTEIN P67PHOX; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZYMOSAN; NEUTROPHIL CYTOSOL FACTOR 40K; OXIDIZING AGENT; PHOSPHOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERICIDAL ACTIVITY; CATALYSIS; CHRONIC GRANULOMATOUS DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; GENE TARGETING; IMMUNE SYSTEM; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUTATION; NEUTROPHIL; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STIMULUS RESPONSE; ANIMAL; BACTERIAL INFECTION; BLOOD CELL COUNT; CELL ADHESION; CELL DIFFERENTIATION; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PHAGOCYTOSIS; SIGNAL TRANSDUCTION; SOLUBILITY;

ANIMALS; BACTERIAL INFECTIONS; BLOOD CELL COUNT; CELL ADHESION; CELL DIFFERENTIATION; FIBRINOGEN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NADPH OXIDASE; NEUTROPHILS; OXIDANTS; PHAGOCYTOSIS; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SOLUBILITY; STAPHYLOCOCCUS AUREUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33746885455     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20052069     Document Type: Article

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