TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology

Nature Immunology

Volumn 8, Issue 12, 2007, Pages 1390-1397

  McGeachy, Mandy J ^a   Bak Jensen, Kristian S ^a   Chen, Yi ^a   Tato, Cristina M ^a   Blumenschein, Wendy ^a   McClanahan, Terrill ^a   Cua, Daniel J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; MYELIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL FUNCTION; CELL LINEAGE; CELL STIMULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENCEPHALITIS; HELPER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; T LYMPHOCYTE; TH17 CELL; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-6; MICE; T-LYMPHOCYTES; T-LYMPHOCYTES, HELPER-INDUCER; TRANSFORMING GROWTH FACTOR BETA;

EID: 36248965294     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1539     Document Type: Article

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