High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: Mechanisms of selection of the self-reactive repertoire

Journal of Experimental Medicine

Volumn 191, Issue 5, 2000, Pages 761-770

  Anderson, A C ^a   Nicholson, L B ^a   Legge, K L ^a   Turchin, V ^a   Zaghouani, H ^a   Kuchroo, V K ^a  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

Autoimmunity; EAE; Major histocompatibility complex and disease; T cell receptor repertoire; Thymic selection

Indexed keywords

EPITOPE; ISOPROTEIN; PROTEOLIPID PROTEIN;

ALLERGIC ENCEPHALITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNITY; CELL SELECTION; CONTROLLED STUDY; FEMALE; IMMUNOSURVEILLANCE; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANIMALS, NEWBORN; AUTOIMMUNITY; BRAIN; CROSS REACTIONS; DISEASE SUSCEPTIBILITY; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GERM-FREE LIFE; H-2 ANTIGENS; IMMUNODOMINANT EPITOPES; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED STRAINS; MYELIN PROTEOLIPID PROTEIN; PEPTIDE FRAGMENTS; SPECIES SPECIFICITY; T-LYMPHOCYTES; THYMUS GLAND;

EID: 0034610973     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.5.761     Document Type: Article

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