Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

Nature Genetics

Volumn 37, Issue 12, 2005, Pages 1317-1319

  Vang, Torkel ^a   Congia, Mauro ^b   Macis, Maria Doloretta ^b   Musumeci, Lucia ^a   Orrú, Valeria ^b,c   Zavattari, Patrizia ^b   Nika, Konstantina ^a   Tautz, Lutz ^a   Taskén, Kjetil ^d   Cucca, Francesco ^b,e   Mustelin, Tomas ^a   Bottini, Nunzio ^a,c  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF OSLO   (Norway)

^e UNIVERSITY OF SASSARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE;

ADDISON DISEASE; ALLELE; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HETEROZYGOSITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ALLELES; ANTIBODIES; AUTOIMMUNE DISEASES; CATALYSIS; DIABETES MELLITUS, TYPE 1; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; INTERLEUKIN-2; ITALY; LYMPHOCYTE ACTIVATION; MALE; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 28444469783     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1673     Document Type: Article

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