-
1
-
-
0029982537
-
Genetic analysis of autoimmune disease
-
PubMed: 8616887
-
Vyse, T.J. and Todd, J.A. (1996) Genetic analysis of autoimmune disease. Cell 85, 311-318, PubMed: 8616887
-
(1996)
Cell
, vol.85
, pp. 311-318
-
-
Vyse, T.J.1
Todd, J.A.2
-
2
-
-
0030716833
-
Genetic susceptibility to the development of autoimmune disease
-
PubMed: 9497784
-
Heward, J. and Gough, S.C. (1997) Genetic susceptibility to the development of autoimmune disease. Clin Sci (Lond) 93, 479-491, PubMed: 9497784
-
(1997)
Clin Sci (Lond)
, vol.93
, pp. 479-491
-
-
Heward, J.1
Gough, S.C.2
-
3
-
-
0033032379
-
Comparative genetics of type 1 diabetes and autoimmune disease: Common loci, common pathways?
-
PubMed: 10389838
-
Becker, K.G. (1999) Comparative genetics of type 1 diabetes and autoimmune disease: Common loci, common pathways? Diabetes 48, 1353-1358, PubMed: 10389838
-
(1999)
Diabetes
, vol.48
, pp. 1353-1358
-
-
Becker, K.G.1
-
4
-
-
0031893204
-
Genetic susceptibility to systemic lupus erythematosus
-
PubMed: 9597131
-
Vyse, T.J. and Kotzin, B.L. (1998) Genetic susceptibility to systemic lupus erythematosus. Annu Rev Immunol 16, 261-292, PubMed: 9597131
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 261-292
-
-
Vyse, T.J.1
Kotzin, B.L.2
-
5
-
-
1842529365
-
Clustering of autoimmune disease in parents of siblings from the Type 1 diabetes Warren repository
-
PubMed: 15049939
-
Tait, K.F. et al. (2004) Clustering of autoimmune disease in parents of siblings from the Type 1 diabetes Warren repository. Diabet Med 21, 358-362, PubMed: 15049939
-
(2004)
Diabet Med
, vol.21
, pp. 358-362
-
-
Tait, K.F.1
-
6
-
-
0026554270
-
Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects
-
PubMed: 1521722
-
Awata, T. et al. (1992) Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia 35, 419-424, PubMed: 1521722
-
(1992)
Diabetologia
, vol.35
, pp. 419-424
-
-
Awata, T.1
-
7
-
-
0029038612
-
Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease
-
PubMed: 7608264
-
Badenhoop, K. et al. (1995) Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease. J Clin Endocrinol Metab 80, 2112-2117, PubMed: 7608264
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 2112-2117
-
-
Badenhoop, K.1
-
8
-
-
19944422075
-
Regression mapping of association between the human leukocyte antigen region and Graves disease
-
PubMed: 15558498
-
Simmonds, M.J. et al. (2005) Regression mapping of association between the human leukocyte antigen region and Graves disease. Am J Hum Genet 76, 157-163, PubMed: 15558498
-
(2005)
Am J Hum Genet
, vol.76
, pp. 157-163
-
-
Simmonds, M.J.1
-
9
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
PubMed: 12724780
-
Ueda, H. et al. (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423, 506-511, PubMed: 12724780
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
-
10
-
-
0032776137
-
The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus
-
PubMed: 10369864
-
Vaidya, B. et al. (1999) The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus. Hum Mol Genet 8, 1195-1199, PubMed: 10369864
-
(1999)
Hum Mol Genet
, vol.8
, pp. 1195-1199
-
-
Vaidya, B.1
-
11
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
PubMed: 15004560
-
Bottini, N. et al. (2004) A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 36, 337-338, PubMed: 15004560
-
(2004)
Nat Genet
, vol.36
, pp. 337-338
-
-
Bottini, N.1
-
12
-
-
7044253358
-
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
-
PubMed: 15504986
-
Smyth, D. et al. (2004) Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes 53, 3020-3023, PubMed: 15504986
-
(2004)
Diabetes
, vol.53
, pp. 3020-3023
-
-
Smyth, D.1
-
13
-
-
11044226181
-
A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families
-
PubMed: 15526003
-
Onengut-Gumuscu, S. et al. (2004) A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families. Genes Immun 5, 678-680, PubMed: 15526003
-
(2004)
Genes Immun
, vol.5
, pp. 678-680
-
-
Onengut-Gumuscu, S.1
-
14
-
-
20144387851
-
Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: The PTPN22 620W allele associates with multiple autoimmune phenotypes
-
PubMed: 15719322
-
Criswell, L.A. et al. (2005) Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: The PTPN22 620W allele associates with multiple autoimmune phenotypes. Am J Hum Genet 76, 561-571, PubMed: 15719322
-
(2005)
Am J Hum Genet
, vol.76
, pp. 561-571
-
-
Criswell, L.A.1
-
15
-
-
11144266638
-
Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes
-
PubMed: 15620463
-
Ladner, M.B. et al. (2005) Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes. Hum Immunol 66, 60-64, PubMed: 15620463
-
(2005)
Hum Immunol
, vol.66
, pp. 60-64
-
-
Ladner, M.B.1
-
16
-
-
8744266374
-
The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease
-
PubMed: 15531553
-
Velaga, M.R. et al. (2004) The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. J Clin Endocrinol Metab 89, 5862-5865, PubMed: 15531553
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5862-5865
-
-
Velaga, M.R.1
-
17
-
-
4143105691
-
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
-
PubMed: 15273934
-
Kyogoku, C. et al. (2004) Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet 75, 504-507, PubMed: 15273934
-
(2004)
Am J Hum Genet
, vol.75
, pp. 504-507
-
-
Kyogoku, C.1
-
18
-
-
19944433325
-
Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus
-
PubMed: 15641066
-
Orozco, G. et al. (2005) Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum 52, 219-224, PubMed: 15641066
-
(2005)
Arthritis Rheum
, vol.52
, pp. 219-224
-
-
Orozco, G.1
-
19
-
-
3242713277
-
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
-
PubMed: 15208781
-
Begovich, A.B. et al. (2004) A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 75, 330-337, PubMed: 15208781
-
(2004)
Am J Hum Genet
, vol.75
, pp. 330-337
-
-
Begovich, A.B.1
-
20
-
-
20144388808
-
The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status
-
PubMed: 15674368
-
Lee, A.T. et al. (2005) The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status. Genes Immun 6, 129-133, PubMed: 15674368
-
(2005)
Genes Immun
, vol.6
, pp. 129-133
-
-
Lee, A.T.1
-
21
-
-
0035960410
-
The thymus and central tolerance
-
PubMed: 11888152
-
Sprent, J. and Kishimoto, H. (2001) The thymus and central tolerance. Transplantation 72, S25-28, PubMed: 11888152
-
(2001)
Transplantation
, vol.72
-
-
Sprent, J.1
Kishimoto, H.2
-
22
-
-
0034773019
-
Mechanisms for the induction of autoimmunity by infectious agents
-
PubMed: 11602615
-
Wucherpfennig, K.W. (2001) Mechanisms for the induction of autoimmunity by infectious agents. J Clin Invest 108, 1097-1104, PubMed: 11602615
-
(2001)
J Clin Invest
, vol.108
, pp. 1097-1104
-
-
Wucherpfennig, K.W.1
-
23
-
-
0036360019
-
The enemy within: Keeping self-reactive T cells at bay in the periphery
-
PubMed: 11908514
-
Walker, L.S. and Abbas, A.K. (2002) The enemy within: Keeping self-reactive T cells at bay in the periphery. Nat Rev Immunol 2, 11-19, PubMed: 11908514
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 11-19
-
-
Walker, L.S.1
Abbas, A.K.2
-
24
-
-
16444366859
-
Genetic insights into disease mechanisms of autoimmunity
-
PubMed: 15701924
-
Simmonds, M.J. and Gough, S.C. (2004) Genetic insights into disease mechanisms of autoimmunity. Br Med Bull 71, 93-113, PubMed: 15701924
-
(2004)
Br Med Bull
, vol.71
, pp. 93-113
-
-
Simmonds, M.J.1
Gough, S.C.2
-
25
-
-
0034084162
-
Regulatory T cells in autoimmmunity
-
PubMed: 10837065
-
Shevach, E.M. (2000) Regulatory T cells in autoimmmunity*. Annu Rev Immunol 18, 423-449, PubMed: 10837065
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 423-449
-
-
Shevach, E.M.1
-
26
-
-
0016177620
-
HL-A antigens and diabetes mellitus
-
PubMed: 4137711
-
Nerup, J. et al. (1974) HL-A antigens and diabetes mellitus. Lancet 2, 864-866, PubMed: 4137711
-
(1974)
Lancet
, vol.2
, pp. 864-866
-
-
Nerup, J.1
-
27
-
-
0036043065
-
Genetics of multiple sclerosis: Linkage and association studies
-
PubMed: 12083953
-
Giordano, M., D'Alfonso, S. and Momigliano-Richiardi, P. (2002) Genetics of multiple sclerosis: Linkage and association studies. Am J Pharmacogenomics 2, 37-58, PubMed: 12083953
-
(2002)
Am J Pharmacogenomics
, vol.2
, pp. 37-58
-
-
Giordano, M.1
D'Alfonso, S.2
Momigliano-Richiardi, P.3
-
28
-
-
3242784052
-
A review of the MHC genetics of rheumatoid arthritis
-
PubMed: 14749714
-
Newton, J.L. et al. (2004) A review of the MHC genetics of rheumatoid arthritis. Genes Immun 5, 151-157, PubMed: 14749714
-
(2004)
Genes Immun
, vol.5
, pp. 151-157
-
-
Newton, J.L.1
-
29
-
-
15144361587
-
Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: Replication using a population case control and family-based study
-
PubMed: 9768636
-
Heward, J.M. et al. (1998) Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: Replication using a population case control and family-based study. J Clin Endocrinol Metab 83, 3394-3397, PubMed: 9768636
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 3394-3397
-
-
Heward, J.M.1
-
30
-
-
0025874086
-
HLA associations with autoimmune Addison's disease
-
PubMed: 1926131
-
Weetman, A.P. et al. (1991) HLA associations with autoimmune Addison's disease. Tissue Antigens 38, 31-33, PubMed: 1926131
-
(1991)
Tissue Antigens
, vol.38
, pp. 31-33
-
-
Weetman, A.P.1
-
31
-
-
1842455656
-
Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond
-
PubMed: 15030506
-
Simmonds, M.J. and Gough, S.C. (2004) Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond. Clin Exp Immunol 136, 1-10, PubMed: 15030506
-
(2004)
Clin Exp Immunol
, vol.136
, pp. 1-10
-
-
Simmonds, M.J.1
Gough, S.C.2
-
32
-
-
18544367934
-
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus
-
PubMed: 12145745
-
Graham, R.R. et al. (2002) Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet 71, 543-553, PubMed: 12145745
-
(2002)
Am J Hum Genet
, vol.71
, pp. 543-553
-
-
Graham, R.R.1
-
33
-
-
0023252262
-
HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
-
PubMed: 3309680
-
Todd, J.A., Bell, J.I. and McDevitt, H.O. (1987) HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329, 599-604, PubMed: 3309680
-
(1987)
Nature
, vol.329
, pp. 599-604
-
-
Todd, J.A.1
Bell, J.I.2
McDevitt, H.O.3
-
34
-
-
3242784051
-
Arginine at position 74 of the HLA-DR beta1 chain is associated with Graves' disease
-
PubMed: 15029234
-
Ban, Y. et al. (2004) Arginine at position 74 of the HLA-DR beta1 chain is associated with Graves' disease. Genes Immun 5, 203-208, PubMed: 15029234
-
(2004)
Genes Immun
, vol.5
, pp. 203-208
-
-
Ban, Y.1
-
35
-
-
0027237554
-
Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia
-
PubMed: 8226139
-
Cucca, F. et al. (1993) Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia. Hum Immunol 37, 85-94, PubMed: 8226139
-
(1993)
Hum Immunol
, vol.37
, pp. 85-94
-
-
Cucca, F.1
-
36
-
-
0029166110
-
The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci
-
PubMed: 7499178
-
Cucca, F. et al. (1995) The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci. Hum Immunol 43, 301-308, PubMed: 7499178
-
(1995)
Hum Immunol
, vol.43
, pp. 301-308
-
-
Cucca, F.1
-
37
-
-
0023500817
-
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
-
PubMed: 2446635
-
Gregersen, P.K., Silver, J. and Winchester, R.J. (1987) The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 30, 1205-1213, PubMed: 2446635
-
(1987)
Arthritis Rheum
, vol.30
, pp. 1205-1213
-
-
Gregersen, P.K.1
Silver, J.2
Winchester, R.J.3
-
38
-
-
0036222676
-
Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule
-
PubMed: 11953968
-
de Vries, N. et al. (2002) Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule. Arthritis Rheum 46, 921-928, PubMed: 11953968
-
(2002)
Arthritis Rheum
, vol.46
, pp. 921-928
-
-
de Vries, N.1
-
39
-
-
0026502380
-
Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics
-
PubMed: 1309938
-
Jorgensen, J.L. et al. (1992) Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature 355, 224-230, PubMed: 1309938
-
(1992)
Nature
, vol.355
, pp. 224-230
-
-
Jorgensen, J.L.1
-
40
-
-
0025296990
-
Analysis of peptide residues interacting with MHC molecule or T cell receptor. Can a peptide bind in more than one way to the same MHC molecule?
-
PubMed: 2141038
-
Kurata, A. and Berzofsky, J.A. (1990) Analysis of peptide residues interacting with MHC molecule or T cell receptor. Can a peptide bind in more than one way to the same MHC molecule? J Immunol 144, 4526-4535, PubMed: 2141038
-
(1990)
J Immunol
, vol.144
, pp. 4526-4535
-
-
Kurata, A.1
Berzofsky, J.A.2
-
41
-
-
0024325587
-
Analysis of peptide binding patterns in different major histocompatibility complex/T cell receptor complexes using pigeon cytochrome c-specific T cell hybridomas. Evidence that a single peptide binds major histocompatibility complex in different conformations
-
PubMed: 2553848
-
Bhayani, H. and Paterson, Y. (1989) Analysis of peptide binding patterns in different major histocompatibility complex/T cell receptor complexes using pigeon cytochrome c-specific T cell hybridomas. Evidence that a single peptide binds major histocompatibility complex in different conformations. J Exp Med 170, 1609-1625, PubMed: 2553848
-
(1989)
J Exp Med
, vol.170
, pp. 1609-1625
-
-
Bhayani, H.1
Paterson, Y.2
-
42
-
-
0034777837
-
A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins
-
PubMed: 11590120
-
Cucca, F. et al. (2001) A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins. Hum Mol Genet 10, 2025-2037, PubMed: 11590120
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2025-2037
-
-
Cucca, F.1
-
43
-
-
0029129476
-
Recognition of multiple peptide cores by a single T cell receptor
-
PubMed: 7629510
-
Nanda, N.K. et al. (1995) Recognition of multiple peptide cores by a single T cell receptor. J Exp Med 182, 531-539, PubMed: 7629510
-
(1995)
J Exp Med
, vol.182
, pp. 531-539
-
-
Nanda, N.K.1
-
44
-
-
0025129103
-
Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition
-
PubMed: 2104922
-
Kwok, W.W. et al. (1990) Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition. J Exp Med 171, 85-95, PubMed: 2104922
-
(1990)
J Exp Med
, vol.171
, pp. 85-95
-
-
Kwok, W.W.1
-
45
-
-
0028348369
-
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
-
PubMed: 8145819
-
Stern, L.J. et al. (1994) Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368, 215-221, PubMed: 8145819
-
(1994)
Nature
, vol.368
, pp. 215-221
-
-
Stern, L.J.1
-
46
-
-
0029986734
-
Recognition of altered self major histocompatibility complex molecules modulated by specific peptide interactions
-
PubMed: 8625994
-
Nepom, G.T. et al. (1996) Recognition of altered self major histocompatibility complex molecules modulated by specific peptide interactions. Eur J Immunol 26, 949-952, PubMed: 8625994
-
(1996)
Eur J Immunol
, vol.26
, pp. 949-952
-
-
Nepom, G.T.1
-
47
-
-
0031847984
-
Molecular basis for HLA-DQ associations with IDDM
-
PubMed: 9703314
-
Nepom, G.T. and Kwok, W.W. (1998) Molecular basis for HLA-DQ associations with IDDM. Diabetes 47, 1177-1184, PubMed: 9703314
-
(1998)
Diabetes
, vol.47
, pp. 1177-1184
-
-
Nepom, G.T.1
Kwok, W.W.2
-
48
-
-
0025131118
-
A unified hypothesis for the complex genetics of HLA associations with IDDM
-
PubMed: 2210067
-
Nepom, G.T. (1990) A unified hypothesis for the complex genetics of HLA associations with IDDM. Diabetes 39, 1153-1157, PubMed: 2210067
-
(1990)
Diabetes
, vol.39
, pp. 1153-1157
-
-
Nepom, G.T.1
-
49
-
-
0036301503
-
CTLA-4: New insights into its biological function and use in tumor immunotherapy
-
PubMed: 12087419
-
Egen, J.G., Kuhns, M.S. and Allison, J.P. (2002) CTLA-4: New insights into its biological function and use in tumor immunotherapy. Nat Immunol 3, 611-618, PubMed: 12087419
-
(2002)
Nat Immunol
, vol.3
, pp. 611-618
-
-
Egen, J.G.1
Kuhns, M.S.2
Allison, J.P.3
-
50
-
-
0024327899
-
Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
-
PubMed: 2653373
-
Mueller, D.L., Jenkins, M.K. and Schwartz, R.H. (1989) Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Annu Rev Immunol 7, 445-480, PubMed: 2653373
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 445-480
-
-
Mueller, D.L.1
Jenkins, M.K.2
Schwartz, R.H.3
-
51
-
-
0033306461
-
The development of Graves' disease and the CTLA-4 gene on chromosome 2q33
-
PubMed: 10404810
-
Heward, J.M. et al. (1999) The development of Graves' disease and the CTLA-4 gene on chromosome 2q33. J Clin Endocrinol Metab 84, 2398-2401, PubMed: 10404810
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 2398-2401
-
-
Heward, J.M.1
-
52
-
-
8944259914
-
The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes
-
Belgian Diabetes Registry. PubMed: 8817351
-
Nistico, L. et al. (1996) The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum Mol Genet 5, 1075-1080, PubMed: 8817351
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1075-1080
-
-
Nistico, L.1
-
53
-
-
0036146702
-
Polymorphism of the CTLA-4 gene is associated with autoimmune hypothyroidism in the United Kingdom
-
PubMed: 11842815
-
Nithiyananthan, R. et al. (2002) Polymorphism of the CTLA-4 gene is associated with autoimmune hypothyroidism in the United Kingdom. Thyroid 12, 3-6, PubMed: 11842815
-
(2002)
Thyroid
, vol.12
, pp. 3-6
-
-
Nithiyananthan, R.1
-
54
-
-
17744373659
-
Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulators (AIRE-1) genes in sporadic autoimmune Addison's disease
-
PubMed: 10690877
-
Vaidya, B. et al. (2000) Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulators (AIRE-1) genes in sporadic autoimmune Addison's disease. J Clin Endocrinol Metab 85, 688-691, PubMed: 10690877
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 688-691
-
-
Vaidya, B.1
-
55
-
-
3242732770
-
Polymorphisms in the cytotoxic T lymphocyte antigen-4 gene region confer susceptibility to Addison's disease
-
PubMed: 15240634
-
Blomhoff, A. et al. (2004) Polymorphisms in the cytotoxic T lymphocyte antigen-4 gene region confer susceptibility to Addison's disease. J Clin Endocrinol Metab 89, 3474-3476, PubMed: 15240634
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 3474-3476
-
-
Blomhoff, A.1
-
56
-
-
2442496304
-
An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells
-
PubMed: 15142525
-
Vijayakrishnan, L. et al. (2004) An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells. Immunity 20, 563-575, PubMed: 15142525
-
(2004)
Immunity
, vol.20
, pp. 563-575
-
-
Vijayakrishnan, L.1
-
57
-
-
0036172220
-
Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength
-
PubMed: 11825563
-
Egen, J.G. and Allison, J.P. (2002) Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength. Immunity 16, 23-35, PubMed: 11825563
-
(2002)
Immunity
, vol.16
, pp. 23-35
-
-
Egen, J.G.1
Allison, J.P.2
-
58
-
-
0030443168
-
Regulation of surface and intracellular expression of CTLA4 on mouse T cells
-
PubMed: 8943377
-
Alegre, M.L. et al. (1996) Regulation of surface and intracellular expression of CTLA4 on mouse T cells. J Immunol 157, 4762-4770, PubMed: 8943377
-
(1996)
J Immunol
, vol.157
, pp. 4762-4770
-
-
Alegre, M.L.1
-
59
-
-
0031132467
-
Synergistic induction of CTLA-4 expression by costimulation with TCR plus CD28 signals mediated by increased transcription and messenger ribonucleic acid stability
-
PubMed: 9126965
-
Finn, P.W. et al. (1997) Synergistic induction of CTLA-4 expression by costimulation with TCR plus CD28 signals mediated by increased transcription and messenger ribonucleic acid stability. J Immunol 158, 4074-4081, PubMed: 9126965
-
(1997)
J Immunol
, vol.158
, pp. 4074-4081
-
-
Finn, P.W.1
-
60
-
-
0030001318
-
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
-
PubMed: 8638161
-
Marengere, L.E. et al. (1996) Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science 272, 1170-1173, PubMed: 8638161
-
(1996)
Science
, vol.272
, pp. 1170-1173
-
-
Marengere, L.E.1
-
61
-
-
0034658408
-
Structural analysis of CTLA-4 function in vivo
-
PubMed: 10799894
-
Masteller, E.L. et al. (2000) Structural analysis of CTLA-4 function in vivo. J Immunol 164, 5319-5327, PubMed: 10799894
-
(2000)
J Immunol
, vol.164
, pp. 5319-5327
-
-
Masteller, E.L.1
-
62
-
-
0033521596
-
Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase
-
PubMed: 9874568
-
Cloutier, J.F. and Veillette, A. (1999) Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase. J Exp Med 189, 111-121, PubMed: 9874568
-
(1999)
J Exp Med
, vol.189
, pp. 111-121
-
-
Cloutier, J.F.1
Veillette, A.2
-
63
-
-
0032545452
-
Molecular basis of T cell inactivation by CTLA-4
-
PubMed: 9856951
-
Lee, K.M. et al. (1998) Molecular basis of T cell inactivation by CTLA-4. Science 282, 2263-2266, PubMed: 9856951
-
(1998)
Science
, vol.282
, pp. 2263-2266
-
-
Lee, K.M.1
-
64
-
-
10344259631
-
Cutting edge: Cbl-b: One of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation
-
PubMed: 15585834
-
LO, D. et al. (2004) Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation. J Immunol 173, 7135-7139, PubMed: 15585834
-
(2004)
J Immunol
, vol.173
, pp. 7135-7139
-
-
Li, D.1
-
65
-
-
3142726114
-
The Cbl family and other ubiquitin ligases: Destructive forces in control of antigen receptor signaling
-
PubMed: 15345216
-
Duan, L. et al. (2004) The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling. Immunity 21, 7-17, PubMed: 15345216
-
(2004)
Immunity
, vol.21
, pp. 7-17
-
-
Duan, L.1
-
66
-
-
0034642499
-
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
-
PubMed: 10646608
-
Bachmaier, K. et al. (2000) Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature 403, 211-216, PubMed: 10646608
-
(2000)
Nature
, vol.403
, pp. 211-216
-
-
Bachmaier, K.1
-
67
-
-
0036699521
-
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus
-
PubMed: 12118252
-
Yokoi, N. et al. (2002) Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet 31, 391-394, PubMed: 12118252
-
(2002)
Nat Genet
, vol.31
, pp. 391-394
-
-
Yokoi, N.1
-
68
-
-
3042654973
-
Protein tyrosine phosphatases in T cell physiology
-
PubMed: 15220004
-
Mustelin, T. et al. (2004) Protein tyrosine phosphatases in T cell physiology. Mol Immunol 41, 687-700, PubMed: 15220004
-
(2004)
Mol Immunol
, vol.41
, pp. 687-700
-
-
Mustelin, T.1
-
69
-
-
0033559313
-
Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp
-
PubMed: 10068674
-
Cohen, S. et al. (1999) Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp. Blood 93, 2013-2024, PubMed: 10068674
-
(1999)
Blood
, vol.93
, pp. 2013-2024
-
-
Cohen, S.1
-
70
-
-
0033842973
-
Subcellular localization of intracellular protein tyrosine phosphatases in T cells
-
PubMed: 10940933
-
Gjorloff-Wingren, A. et al. (2000) Subcellular localization of intracellular protein tyrosine phosphatases in T cells. Eur J Immunol 30, 2412-2421, PubMed: 10940933
-
(2000)
Eur J Immunol
, vol.30
, pp. 2412-2421
-
-
Gjorloff-Wingren, A.1
-
71
-
-
0036186527
-
The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation
-
PubMed: 11882361
-
Hill, R.J. et al. (2002) The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation. Exp Hematol 30, 237-244, PubMed: 11882361
-
(2002)
Exp Hematol
, vol.30
, pp. 237-244
-
-
Hill, R.J.1
-
72
-
-
20844452226
-
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
-
PubMed: 15759012
-
Viken, M.K. et al. (2005) Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases. Genes Immun 6, 271-273, PubMed: 15759012
-
(2005)
Genes Immun
, vol.6
, pp. 271-273
-
-
Viken, M.K.1
-
73
-
-
11144292728
-
The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis
-
PubMed: 15580548
-
Begovich, A.B. et al. (2005) The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis. Am J Hum Genet 76, 184-187, PubMed: 15580548
-
(2005)
Am J Hum Genet
, vol.76
, pp. 184-187
-
-
Begovich, A.B.1
-
74
-
-
23844551123
-
Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis
-
PubMed: 15765267
-
Matesanz, F. et al. (2005) Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis. J Neurol PubMed: 15765267
-
(2005)
J Neurol
-
-
Matesanz, F.1
-
75
-
-
0029348006
-
The Src and Csk families of tyrosine protein kinases in hemopoietic cells
-
PubMed: 8520026
-
Chow, L.M. and Veillette, A. (1995) The Src and Csk families of tyrosine protein kinases in hemopoietic cells. Semin Immunol 7, 207-226, PubMed: 8520026
-
(1995)
Semin Immunol
, vol.7
, pp. 207-226
-
-
Chow, L.M.1
Veillette, A.2
-
76
-
-
0027240587
-
Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk
-
PubMed: 8371758
-
Chow, L.M. et al. (1993) Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk. Nature 365, 156-160, PubMed: 8371758
-
(1993)
Nature
, vol.365
, pp. 156-160
-
-
Chow, L.M.1
-
77
-
-
0032572720
-
Csk controls antigen receptor-mediated development and selection of T-lineage cells
-
PubMed: 9732874
-
Schmedt, C. et al. (1998) Csk controls antigen receptor-mediated development and selection of T-lineage cells. Nature 394, 901-904, PubMed: 9732874
-
(1998)
Nature
, vol.394
, pp. 901-904
-
-
Schmedt, C.1
-
78
-
-
0034753803
-
A novel, specific interaction involving the Csk SH3 domain and its natural ligand
-
PubMed: 11685249
-
Ghose, R. et al. (2001) A novel, specific interaction involving the Csk SH3 domain and its natural ligand. Nat Struct Biol 8, 998-1004, PubMed: 11685249
-
(2001)
Nat Struct Biol
, vol.8
, pp. 998-1004
-
-
Ghose, R.1
-
79
-
-
0242712698
-
Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP
-
PubMed: 10601992
-
Gjorloff-Wingren, A. et al. (1999) Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP. Eur J Immunol 29, 3845-3854, PubMed: 10601992
-
(1999)
Eur J Immunol
, vol.29
, pp. 3845-3854
-
-
Gjorloff-Wingren, A.1
-
80
-
-
0030889218
-
The product of the proto-oncogene c-cbl: A negative regulator of the Syk tyrosine kinase
-
PubMed: 9103201
-
Ota, Y. and Samelson, L.E. (1997) The product of the proto-oncogene c-cbl: A negative regulator of the Syk tyrosine kinase. Science 276, 418-420, PubMed: 9103201
-
(1997)
Science
, vol.276
, pp. 418-420
-
-
Ota, Y.1
Samelson, L.E.2
-
81
-
-
14444276991
-
The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70
-
PubMed: 9407100
-
Lupher, M.L., Jr. et al. (1997) The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70. J Biol Chem 272, 33140-33144, PubMed: 9407100
-
(1997)
J Biol Chem
, vol.272
, pp. 33140-33144
-
-
Lupher Jr., M.L.1
-
82
-
-
0032478805
-
Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells
-
PubMed: 9525940
-
Feshchenko, E.A., Langdon, W.Y. and Tsygankov, A.Y. (1998) Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells. J Biol Chem 273, 8323-8331, PubMed: 9525940
-
(1998)
J Biol Chem
, vol.273
, pp. 8323-8331
-
-
Feshchenko, E.A.1
Langdon, W.Y.2
Tsygankov, A.Y.3
-
83
-
-
0028940733
-
T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras
-
PubMed: 7737275
-
Schneider, H. et al. (1995) T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras. Eur J Immunol 25, 1044-1050, PubMed: 7737275
-
(1995)
Eur J Immunol
, vol.25
, pp. 1044-1050
-
-
Schneider, H.1
-
84
-
-
0031962106
-
Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling
-
PubMed: 9417079
-
Kim, H.H., Tharayil, M. and Rudd, C.E. (1998) Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling. J Biol Chem 273, 296-301, PubMed: 9417079
-
(1998)
J Biol Chem
, vol.273
, pp. 296-301
-
-
Kim, H.H.1
Tharayil, M.2
Rudd, C.E.3
-
85
-
-
0032516873
-
Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction
-
PubMed: 9694876
-
Okkenhaug, K. and Rottapel, R. (1998) Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction. J Biol Chem 273, 21194-21202, PubMed: 9694876
-
(1998)
J Biol Chem
, vol.273
, pp. 21194-21202
-
-
Okkenhaug, K.1
Rottapel, R.2
|