메뉴 건너뛰기




Volumn 18, Issue 36, 2011, Pages 5483-5506

Glutamate binding-site ligands of NMDA receptors

Author keywords

Competitive agonists; Competitive antagonists; Glutamate; NMDA receptors

Indexed keywords

4 METHYLGLUTAMIC ACID; ASPARTIC ACID; CONANTOKIN G; CYCLIN DEPENDENT KINASE 5; DECAHYDROISOQUINOLINE; DYSIHERBAINE; GLUTAMIC ACID; GLYCINE; IBOTENIC ACID; ISOXAZOLINE DERIVATIVE; LIGAND; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OMEGA PHOSPHONO ALPHA AMINO ACID DERIVATIVE; QUINOLINIC ACID; QUINOXALINEDIONE DERIVATIVE; SERINE; TETRAHYDROISOQUINOLINE; TRICHOLOMIC ACID; UNCLASSIFIED DRUG;

EID: 84055183958     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986711798347225     Document Type: Article
Times cited : (19)

References (197)
  • 1
    • 0037452854 scopus 로고    scopus 로고
    • Glutamate receptor function in learning and memory
    • DOI 10.1016/S0166-4328(02)00272-3, PII S0166432802002723
    • Riedel, G.; Platt, B.; Micheau, J. Glutamate receptor function in learning and memory. Behav. Brain Res., 2003, 140, 1-47. (Pubitemid 36313239)
    • (2003) Behavioural Brain Research , vol.140 , Issue.1-2 , pp. 1-47
    • Riedel, G.1    Platt, B.2    Micheau, J.3
  • 4
    • 0036830627 scopus 로고    scopus 로고
    • NMDA receptor pathways as drug targets
    • DOI 10.1038/nn936
    • Kemp, J.A.; McKernan, R.M. NMDA receptor pathways as drug targets. Nature Neurosci, 2002, 5, 1039-1042. (Pubitemid 35247194)
    • (2002) Nature Neuroscience , vol.5 , Issue.SUPPL. , pp. 1039-1042
    • Kemp, J.A.1    McKernan, R.M.2
  • 6
    • 0032523002 scopus 로고    scopus 로고
    • Evidence for a tetrameric structure of recombinant NMDA receptors
    • Laube, B.; Kuhse, J.; Betz, H. Evidence for a tetrameric structure of recombinant NMDA receptors. J. Neurosci., 1998, 18, 2954-2961. (Pubitemid 28163225)
    • (1998) Journal of Neuroscience , vol.18 , Issue.8 , pp. 2954-2961
    • Laube, B.1    Kuhse, J.2    Betz, H.3
  • 8
    • 33846920665 scopus 로고    scopus 로고
    • NMDA receptor subunits: Function and pharmacology
    • DOI 10.1016/j.coph.2006.08.011, PII S1471489206001883, Neurosciences
    • Paoletti, P.; Neyton, J. NMDA receptor subunits: function and pharmacology. Curr. Opin. Pharmacol., 2007, 7, 39-47. (Pubitemid 46238036)
    • (2007) Current Opinion in Pharmacology , vol.7 , Issue.1 , pp. 39-47
    • Paoletti, P.1    Neyton, J.2
  • 9
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • DOI 10.1016/S0959-4388(00)00215-4
    • Cull-Candy, S.; Brickley, S.; Farrant, M. NMDA receptor subunits: diversity, development and disease. Curr. Opin. Neurobiol., 2001, 11, 327-35. (Pubitemid 32524098)
    • (2001) Current Opinion in Neurobiology , vol.11 , Issue.3 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 10
    • 72049124287 scopus 로고    scopus 로고
    • X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
    • Sobolevsky, A.I.; Rosconi, M.P.; Gouaux, E. X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature, 2009, 462, 745-756.
    • (2009) Nature , vol.462 , pp. 745-756
    • Sobolevsky, A.I.1    Rosconi, M.P.2    Gouaux, E.3
  • 13
    • 33646849232 scopus 로고    scopus 로고
    • Characterization of a soluble ligand binding domain of the NMDA receptor regulatory subunit NR3A
    • DOI 10.1523/JNEUROSCI.0560-06.2006
    • Yao, Y.; Mayer, M.L. Characterization of a soluble ligand binding domain of the NMDA receptor regulatory subunit NR3A. J. Neurosci., 2006, 26, 4559-4566. (Pubitemid 44315355)
    • (2006) Journal of Neuroscience , vol.26 , Issue.17 , pp. 4559-4566
    • Yao, Y.1    Mayer, M.L.2
  • 14
    • 50449105436 scopus 로고    scopus 로고
    • Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist
    • Madry, C.; Betz, H.; Geiger, J.R.P.; Laube, B. Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist. Proc. Natl. Acad. Sci., 2008, 105, 12563-12568.
    • (2008) Proc. Natl. Acad. Sci. , vol.105 , pp. 12563-12568
    • Madry, C.1    Betz, H.2    Geiger, J.R.P.3    Laube, B.4
  • 15
    • 66649086928 scopus 로고    scopus 로고
    • Mechanism of differential control of NMDA receptor activity by NR2 subunits
    • Gielen, M.; Retchless, B.S.; Mony, L.; Johnson, J.W.; Paoletti, P. Mechanism of differential control of NMDA receptor activity by NR2 subunits. Nature, 2009, 459, 703-707.
    • (2009) Nature , vol.459 , pp. 703-707
    • Gielen, M.1    Retchless, B.S.2    Mony, L.3    Johnson, J.W.4    Paoletti, P.5
  • 16
    • 79960417429 scopus 로고    scopus 로고
    • Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors
    • Karakas, E.; Simorowski, N.; Furukawa, H. Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature, 2011, 475, 249-253.
    • (2011) Nature , vol.475 , pp. 249-253
    • Karakas, E.1    Simorowski, N.2    Furukawa, H.3
  • 17
    • 34250158705 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate antagonists and neuropathic pain: The search for relief
    • Childers, W.E.; Baudy, R.B.Jr. N-Methyl-D-aspartate antagonists and neuropathic pain: the search for relief. J. Med. Chem., 2007, 50, 2557-2562.
    • (2007) J. Med. Chem. , vol.50 , pp. 2557-2562
    • Childers, W.E.1    Baudy Jr., R.B.2
  • 18
    • 1242351945 scopus 로고    scopus 로고
    • The NMDA receptor NR2B subunit: A valid therapeutic target for multiple CNS pathologies
    • DOI 10.2174/0929867043456061
    • Chazot, P.L. The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies. Curr. Med. Chem., 2004, 11, 389-396. (Pubitemid 38240214)
    • (2004) Current Medicinal Chemistry , vol.11 , Issue.3 , pp. 389-396
    • Chazot, P.L.1
  • 19
    • 33646537447 scopus 로고    scopus 로고
    • NR2B selective NMDA antagonists: The evolution of the ifenprodil-type pharmacophore
    • Borza, I.; Domany, G. NR2B selective NMDA antagonists: the evolution of the ifenprodil-type pharmacophore. Curr. Top. Med. Chem., 2006, 6, 687-695.
    • (2006) Curr. Top. Med. Chem. , vol.6 , pp. 687-695
    • Borza, I.1    Domany, G.2
  • 20
    • 33646594995 scopus 로고    scopus 로고
    • Recent advances in the development of NR2B subtype-selective NMDA receptor antagonists
    • Layton, M.E.; Kelly, M.J.3rd; Rodzinak, K.J. Recent advances in the development of NR2B subtype-selective NMDA receptor antagonists. Curr. Top. Med. Chem., 2006, 6, 697-709.
    • (2006) Curr. Top. Med. Chem. , vol.6 , pp. 697-709
    • Layton, M.E.1    Kelly III, M.J.2    Rodzinak, K.J.3
  • 21
    • 78649301895 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor antagonists: A review of compounds patented since 2006
    • Koller, M.; Urwyler, S. Novel N-methyl-D-aspartate receptor antagonists: a review of compounds patented since 2006. Expert Opin. Ther. Patents, 2010, 20, 1683-1702.
    • (2010) Expert Opin. Ther. Patents , vol.20 , pp. 1683-1702
    • Koller, M.1    Novel, U.S.2
  • 22
    • 12844268621 scopus 로고    scopus 로고
    • The function of the amino terminal domain in NMDA receptor modulation
    • DOI 10.1016/j.jmgm.2004.11.006, PII S1093326304001093
    • Huggins, D.J.; Grant, G.H. The function of the amino terminal domain in NMDA receptor modulation. J. Mol. Graph. Model, 2005, 23, 381-388. (Pubitemid 40164751)
    • (2005) Journal of Molecular Graphics and Modelling , vol.23 , Issue.4 , pp. 381-388
    • Huggins, D.J.1    Grant, G.H.2
  • 23
    • 0037764736 scopus 로고    scopus 로고
    • Acid tests of N-methyl-D-aspartate receptor gating basics
    • DOI 10.1124/mol.63.6.1199
    • Johnson, J.W. Acid tests of N-methyl-D-aspartate receptor gating basics. Mol. Pharmacol. 2003, 63, 1199-1201. (Pubitemid 36627211)
    • (2003) Molecular Pharmacology , vol.63 , Issue.6 , pp. 1199-1201
    • Johnson, J.W.1
  • 24
    • 33645321641 scopus 로고    scopus 로고
    • Glutamate receptors at atomic resolution
    • Mayer, M.L. Glutamate receptors at atomic resolution. Nature, 2006, 440, 456-462.
    • (2006) Nature , vol.440 , pp. 456-462
    • Mayer, M.L.1
  • 25
    • 0034517709 scopus 로고    scopus 로고
    • Molecular organization of a zinc binding N-terminal modulatory domain in a NMDA receptor subunit
    • DOI 10.1016/S0896-6273(00)00163-X
    • Paoletti P.; Perin-Dureau F.; Fayyazuddin A.; Le Goff A.; Callebaut I.; Neyton J. Molecular organization of a zinc binding N-terminal modulatory domain in a NMDA receptor subunit. Neuron, 2000, 28, 911-925. (Pubitemid 32038081)
    • (2000) Neuron , vol.28 , Issue.3 , pp. 911-925
    • Paoletti, P.1    Perin-Dureau, F.2    Fayyazuddin, A.3    Le Goff, A.4    Callebaut, I.5    Neyton, J.6
  • 26
    • 12144257176 scopus 로고    scopus 로고
    • The micromolar zinc-binding domain on the NMDA receptor subunit NR2B
    • DOI 10.1523/JNEUROSCI.3967-04.2005
    • Rachline, J.; Perin-Dureau, F.; Le Goff, A.; Neyton, J.; Paoletti, P. The micromolar zinc-binding domain on the NMDA receptor subunit NR2B. J. Neurosci., 2005, 25, 308-317. (Pubitemid 40105601)
    • (2005) Journal of Neuroscience , vol.25 , Issue.2 , pp. 308-317
    • Rachline, J.1    Perin-Dureau, F.2    Le Goff, A.3    Neyton, J.4    Paoletti, P.5
  • 27
    • 0038037859 scopus 로고    scopus 로고
    • Mechanisms of activation, inhibition and specificity: Crystal structures of the NMDA receptor NR1 ligand-binding core
    • DOI 10.1093/emboj/cdg303
    • Furukawa, H.; Gouaux, E. Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core. EMBO J., 2003, 12, 2873-2885. (Pubitemid 36758609)
    • (2003) EMBO Journal , vol.22 , Issue.12 , pp. 2873-2885
    • Furukawa, H.1    Gouaux, E.2
  • 28
    • 20444408992 scopus 로고    scopus 로고
    • Mechanism of partial agonist action at the NR1 subunit of NMDA receptors
    • DOI 10.1016/j.neuron.2005.05.022, PII S0896627305004691
    • Inanobe, A.; Furukawa, H.; Gouaux. E. Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron, 2005, 47, 71-84. (Pubitemid 40922851)
    • (2005) Neuron , vol.47 , Issue.1 , pp. 71-84
    • Inanobe, A.1    Furukawa, H.2    Gouaux, E.3
  • 30
    • 0026727807 scopus 로고
    • Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor
    • Burnashev, N.; Schoepfer, R.; Monyer, H.; Ruppersberg, J.P.; Gunther, W.; Seeburg, P.H.; Sakmann, B. Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. Science, 1992, 257, 1415-1459.
    • (1992) Science , vol.257 , pp. 1415-1459
    • Burnashev, N.1    Schoepfer, R.2    Monyer, H.3    Ruppersberg, J.P.4    Gunther, W.5    Seeburg, P.H.6    Sakmann, B.7
  • 31
    • 70450184777 scopus 로고    scopus 로고
    • Single-channel properties of N-methyl-Daspartate receptors containing chimaeric GluN2A/GluN2D subunits
    • O'Leary, T.; Wyllie, D.J.A. Single-channel properties of N-methyl-Daspartate receptors containing chimaeric GluN2A/GluN2D subunits. Biochem. Soc. Trans., 2009, 37, 1347-1354.
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 1347-1354
    • O'Leary, T.1    Wyllie, D.J.A.2
  • 32
    • 48749130638 scopus 로고    scopus 로고
    • NMDA receptor subtypes: Structure, function and therapeutics
    • Chaffey, H.; Chazot, P.L. NMDA receptor subtypes: structure, function and therapeutics. Curr. Anaesth. Crit. Care, 2008, 19, 183-201.
    • (2008) Curr. Anaesth. Crit. Care , vol.19 , pp. 183-201
    • Chaffey, H.1    Chazot, P.L.2
  • 33
    • 0037197774 scopus 로고    scopus 로고
    • Cloning and characterization of a novel NMDA receptor subunit NR3B: A dominant subunit that reduces calcium permeability
    • DOI 10.1016/S0169-328X(02)00173-0, PII S0169328X02001730
    • Matsuda, K.; Kamiya, Y.; Matsuda, S.; Yuzaki, M. Cloning and characterization of a novel NMDA receptor subunit NR3B: a dominant subunit that reduces calcium permeability. Brain Res. Mol. Brain Res., 2002, 100, 43-52. (Pubitemid 34465577)
    • (2002) Molecular Brain Research , vol.100 , Issue.1-2 , pp. 43-52
    • Matsuda, K.1    Kamiya, Y.2    Matsuda, S.3    Yuzaki, M.4
  • 34
    • 0043236359 scopus 로고    scopus 로고
    • Motoneuronspecific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner
    • Nishi, M.; Hinds, H.; Lu, H.P.; Kawata, M.; Hayashi, Y. Motoneuronspecific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner. J. Neurosci., 2001, 21, 1-6.
    • (2001) J. Neurosci. , vol.21 , pp. 1-6
    • Nishi, M.1    Hinds, H.2    Lu, H.P.3    Kawata, M.4    Hayashi, Y.5
  • 35
    • 0037216407 scopus 로고    scopus 로고
    • The N-methyl-D-aspartate receptor subunit NR2B: Localization, functional properties, regulation, and clinical implications
    • DOI 10.1016/S0163-7258(02)00302-9, PII S0163725802003029
    • Loftis, J.M.; Janowsky, A. The N-methyl-D-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications. Pharmacol. Ther., 2003, 97, 55-85. (Pubitemid 35477804)
    • (2003) Pharmacology and Therapeutics , vol.97 , Issue.1 , pp. 55-85
    • Loftis, J.M.1    Janowsky, A.2
  • 36
    • 0030864283 scopus 로고    scopus 로고
    • Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies
    • DOI 10.1016/S0169-328X(97)00206-4, PII S0169328X97002064
    • Laurie, D.J.; Bartke, I.; Schoepfer, R.; Naujoks, K.; Seeburg, P.H. Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies. Brain Res Mol Brain Res, 1997, 51, 23-32. (Pubitemid 27504028)
    • (1997) Molecular Brain Research , vol.51 , Issue.1-2 , pp. 23-32
    • Laurie, D.J.1    Bartke, I.2    Schoepfer, R.3    Naujoks, K.4    Seeburg, P.H.5
  • 37
    • 0030022433 scopus 로고    scopus 로고
    • Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain
    • Wenzel, A.; Villa, M.; Mohler, H.; Benke, D. Developmental and Regional Expression of NMDA Receptor Subtypes Containing the NR2D Subunit in Rat Brain. J. Neurochem., 1996, 66, 1240-1248. (Pubitemid 26065924)
    • (1996) Journal of Neurochemistry , vol.66 , Issue.3 , pp. 1240-1248
    • Wenzel, A.1    Villa, M.2    Mohler, H.3    Benke, D.4
  • 38
    • 67349136362 scopus 로고    scopus 로고
    • Role of distinct NMDA receptor subtypes at central synapses
    • Cull-Candy, S.G.; Leszkiewics, D.N. Role of distinct NMDA receptor subtypes at central synapses. Sci STKE, 2004, 16, 1-9.
    • (2004) Sci STKE , vol.16 , pp. 1-9
    • Cull-Candy, S.G.1    Leszkiewics, D.N.2
  • 40
    • 24744440576 scopus 로고    scopus 로고
    • Mechanism-based targeting of NMDA receptor functions
    • DOI 10.1007/s00018-005-5227-8
    • Popescu, G. Mechanism-based targeting of NMDA receptor functions. Cell Mol. Life Sci., 2005, 62, 2100-2111. (Pubitemid 41291666)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.18 , pp. 2100-2111
    • Popescu, G.1
  • 41
    • 33745685529 scopus 로고    scopus 로고
    • Plasticity in the human central nervous system
    • DOI 10.1093/brain/awl082
    • Cooke, S.F.; Bliss, T.V.P. Plasticity in the human central nervous system. Brain, 2006, 129, 1659-1673. (Pubitemid 43999401)
    • (2006) Brain , vol.129 , Issue.7 , pp. 1659-1673
    • Cooke, S.F.1    Bliss, T.V.P.2
  • 42
    • 0042536473 scopus 로고    scopus 로고
    • Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
    • DOI 10.1016/S0143-4160(03)00141-6
    • Arundine, M.; Tymianski, M. Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium, 2003, 34, 325-337. (Pubitemid 37021228)
    • (2003) Cell Calcium , vol.34 , Issue.4-5 , pp. 325-337
    • Arundine, M.1    Tymianski, M.2
  • 43
    • 0025368726 scopus 로고
    • Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents
    • Lester, R.A.; Clements, J.D.; Westbrook, G.L.; Jahr, C.E. Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents. Nature, 1990, 346, 565-567.
    • (1990) Nature , vol.346 , pp. 565-567
    • Lester, R.A.1    Clements, J.D.2    Westbrook, G.L.3    Jahr, C.E.4
  • 44
    • 0029944179 scopus 로고    scopus 로고
    • Kinetics of NMDA channel opening
    • Dzubay, J.A.; Jahr, C.E. Kinetics of NMDA channel opening. J. Neurosci., 1996, 16, 4129-4134. (Pubitemid 26192408)
    • (1996) Journal of Neuroscience , vol.16 , Issue.13 , pp. 4129-4134
    • Dzubay, J.A.1    Jahr, C.E.2
  • 46
    • 79955538759 scopus 로고    scopus 로고
    • Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors
    • Vance, K.M.; Somorowski, N.; Traynelis, S.F.; Furukawa, H. Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors. Nature Comm. 2011, 2:294.
    • (2011) Nature Comm. , vol.2 , pp. 294
    • Vance, K.M.1    Somorowski, N.2    Traynelis, S.F.3    Furukawa, H.4
  • 47
    • 0030997418 scopus 로고    scopus 로고
    • Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition
    • Chen, N.; Moshaver, A.; Raymond, L.A. Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition. Mol. Pharmacol., 1997, 51, 1015-1023. (Pubitemid 27249135)
    • (1997) Molecular Pharmacology , vol.51 , Issue.6 , pp. 1015-1023
    • Chen, N.1    Moshaver, A.2    Raymond, L.A.3
  • 48
    • 0033697745 scopus 로고    scopus 로고
    • Four residues of the extracellular N-terminal domain of the NR2A subunit control high-affinity Zn2+ binding to NMDA receptors
    • Fayyazuddin, A.; Villarroel, A.; Le Goff, A.; Lerma, J.; Neyton. J. Four residues of the extracellular N-terminal domain of the NR2A subunit control high-affinity Zn2+ binding to NMDA receptors. Neuron, 2000, 25, 683-694.
    • (2000) Neuron , vol.25 , pp. 683-694
    • Fayyazuddin, A.1    Villarroel, A.2    Le Goff, A.3    Lerma, J.4    Neyton, J.5
  • 49
    • 0034718494 scopus 로고    scopus 로고
    • Molecular determinants of coordinated proton and zinc inhibition of N-methyl-Daspartate NR1/NR2A receptors
    • Low, C.M.; Zheng, F.; Lyuboslavsky, P.; Traynelis. S.F. Molecular determinants of coordinated proton and zinc inhibition of N-methyl-Daspartate NR1/NR2A receptors. Proc. Acad. Natl. Sci., 2000, 97, 11062-11067.
    • (2000) Proc. Acad. Natl. Sci. , vol.97 , pp. 11062-11067
    • Low, C.M.1    Zheng, F.2    Lyuboslavsky, P.3    Traynelis, S.F.4
  • 50
    • 0025053207 scopus 로고
    • The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat neurones
    • Legendre, P.; Westbrook G.L. The inhibition of single N-methyl-D-aspartateactivated channels by zinc ions on cultured rat neurones. J. Physiol., 1990, 429, 429-449. (Pubitemid 20327560)
    • (1990) Journal of Physiology , vol.429 , pp. 429-449
    • Legendre, P.1    Westbrook, G.L.2
  • 51
    • 0034517709 scopus 로고    scopus 로고
    • Molecular organization of a zinc binding N-terminal modulatory domain in a NMDA receptor subunit
    • Paoletti, P.; Perin-Dureau, F.; Fayyazuddin, A.; Le Goff, A.; Callebaut, I.; Neyton, J. Molecular organization of a zinc binding N-terminal modulatory domain in a NMDA receptor subunit. Neuron, 2000, 28, 911-955.
    • (2000) Neuron , vol.28 , pp. 911-955
    • Paoletti, P.1    Perin-Dureau, F.2    Fayyazuddin, A.3    Le Goff, A.4    Callebaut, I.5    Neyton, J.6
  • 52
    • 72449151659 scopus 로고    scopus 로고
    • Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit
    • Karakas, E.; Simorowski, N.; Furukawa. H. Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. EMBO J., 2009, 28, 3910-3920.
    • (2009) EMBO J. , vol.28 , pp. 3910-3920
    • Karakas, E.1    Simorowski, N.2    Furukawa, H.3
  • 53
    • 0034308638 scopus 로고    scopus 로고
    • Recent development in NMDA receptors
    • Liu, Y.; Zhang, J. Recent development in NMDA receptors. Chinese Med. J., 2000, 113, 948-956.
    • (2000) Chinese Med. J. , vol.113 , pp. 948-956
    • Liu, Y.1    Zhang, J.2
  • 54
    • 0030047530 scopus 로고    scopus 로고
    • Modulation of channel function by polyamines
    • DOI 10.1016/0165-6147(96)81566-5
    • Johnson, T.D. Modulation of channel function by polyamines. Trends Pharmacol. Sci., 1996, 17, 22-27. (Pubitemid 26027737)
    • (1996) Trends in Pharmacological Sciences , vol.17 , Issue.1 , pp. 22-27
    • Johnson, T.D.1
  • 55
    • 0030860597 scopus 로고    scopus 로고
    • Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: Role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits
    • Kashiwagi, K.; Pahk, A.J.; Masuko, T.; Igarashi, K.; Williams, K. Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits. Mol Pharmacol., 1997, 52, 701-713. (Pubitemid 27443993)
    • (1997) Molecular Pharmacology , vol.52 , Issue.4 , pp. 701-713
    • Kashiwagi, K.1    Pahk, A.J.2    Masuko, T.3    Igarashi, K.4    Williams, K.5
  • 56
    • 0028360327 scopus 로고
    • Regulation of NMDA receptors by tyrosine kinases and phosphatases
    • DOI 10.1038/369233a0
    • Wang, Y.T.; Salter, M.W. Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature, 1994, 69, 233-235. (Pubitemid 24154800)
    • (1994) Nature , vol.369 , Issue.6477 , pp. 233-235
    • Wang, Y.T.1    Salter, M.W.2
  • 57
    • 1842731881 scopus 로고    scopus 로고
    • SRC kinases: A hub for NMDA receptor regulation
    • Salter, M.W.; Kalia, L.V. Src kinases: a hub for NMDA receptor regulation. Nat. Rev. Neurosci., 2004, 5, 317-328. (Pubitemid 38478658)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.4 , pp. 317-328
    • Salter, M.W.1    Kalia, L.V.2
  • 58
    • 20544432404 scopus 로고    scopus 로고
    • Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms
    • DOI 10.1016/j.neuint.2005.04.011, PII S0197018605000963
    • Sanchez-Pérez, A.M.; Felipe, V. Serines 890 and 896 of the NMDA receptor subunit NR1 are differentially phosphorylated by protein kinase C isoforms. Neurochem. Int., 2005, 47, 84-91. (Pubitemid 40848697)
    • (2005) Neurochemistry International , vol.47 , Issue.1-2 SPEC. ISS. , pp. 84-91
    • Sanchez-Perez, A.M.1    Felipo, V.2
  • 59
    • 1542614144 scopus 로고    scopus 로고
    • Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors
    • DOI 10.1016/S0028-3908(03)00250-8, PII S0028390803002508
    • Scott, D.B.; Blanpied, T.A.; Ehlers, M.D. Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors. Neuropharmacol., 2003, 45, 755-767. (Pubitemid 38340361)
    • (2003) Neuropharmacology , vol.45 , Issue.6 , pp. 755-767
    • Scott, D.B.1    Blanpied, T.A.2    Ehlers, M.D.3
  • 61
    • 0141542665 scopus 로고    scopus 로고
    • Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
    • DOI 10.1038/nn1119
    • Wang, J.; Liu, S.H.; Fu, Y.P.; Wang, J.H.; Lu, Y.M. Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. Nat. Neurosci., 2003, 6, 1039-1047. (Pubitemid 37186195)
    • (2003) Nature Neuroscience , vol.6 , Issue.10 , pp. 1039-1047
    • Wang, J.1    Liu, S.2    Fu, Y.3    Wang, J.H.4    Lu, Y.5
  • 62
    • 0032106760 scopus 로고    scopus 로고
    • Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition
    • Zheng, F.; Gingrich, M.B.; Traynelis, S.F.; Conn P.J. Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition. Nat. Neurosci., 1998, 1, 185-191.
    • (1998) Nat. Neurosci. , vol.1 , pp. 185-191
    • Zheng, F.1    Gingrich, M.B.2    Traynelis, S.F.3    Conn, P.J.4
  • 63
    • 0033223820 scopus 로고    scopus 로고
    • Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition
    • Xiong, Z.G.; Pelkey, K.A.; Lu, W.Y.; Lu, Y.M.; Roder, J.C.; MacDonald, J.F.; Salter, M.W. Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. J. Neurosci., 1999, 19, RC37.
    • (1999) J. Neurosci. , vol.19
    • Xiong, Z.G.1    Pelkey, K.A.2    Lu, W.Y.3    Lu, Y.M.4    Roder, J.C.5    MacDonald, J.F.6    Salter, M.W.7
  • 64
    • 0034899681 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases
    • DOI 10.1046/j.1471-4159.2001.00433.x
    • Cheung, H.H., Gurd, J.W. Tyrosine phosphorylation of the N-methyl-Daspartate receptor by exogenous and postsynaptic density-associated Srcfamily kinases. J. Neurochem., 2001, 78, 524-534. (Pubitemid 32729980)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.3 , pp. 524-534
    • Cheung, H.H.1    Gurd, J.W.2
  • 65
  • 67
    • 8544232133 scopus 로고    scopus 로고
    • Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand
    • DOI 10.1523/JNEUROSCI.0546-04.2004
    • Chung, H.J.; Huang, Y.H.; Lau, L.F.; Huganir, R.L. Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand. J. Neurosci., 2004, 24, 10248-10259. (Pubitemid 39492052)
    • (2004) Journal of Neuroscience , vol.24 , Issue.45 , pp. 10248-10259
    • Hee, J.C.1    Yan, H.H.2    Lau, L.-F.3    Huganir, R.L.4
  • 68
    • 0001048711 scopus 로고    scopus 로고
    • Src activation in the induction of long-term potentiation in CA1 hippocampal neurons
    • Lu, Y.M.; Roder, J.C.; Davidow, J.; Salter, M.W. Src activation in the induction of long-term potentiation in CA1 hippocampal neurons. Science, 1998, 279, 1363-1368.
    • (1998) Science , vol.279 , pp. 1363-1368
    • Lu, Y.M.1    Roder, J.C.2    Davidow, J.3    Salter, M.W.4
  • 69
    • 0035859082 scopus 로고    scopus 로고
    • Interaction with the NMDA receptor locks CaMKII in an active conformation
    • DOI 10.1038/35081080
    • Bayer, K.U.; De Koninck, P.; Leonard, A.S.; Hell, J.W.; Schulman. H. Interaction with the NMDA receptor locks CaMKII in an active conformation. Nature, 2001, 411, 801-805. (Pubitemid 32588103)
    • (2001) Nature , vol.411 , Issue.6839 , pp. 801-805
    • Bayer, K.-U.1    De Koninck, P.2    Leonard, A.S.3    Hell, J.W.4    Schulman, H.5
  • 70
    • 26944487610 scopus 로고    scopus 로고
    • NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII
    • DOI 10.1016/j.neuron.2005.08.034, PII S0896627305007385
    • Barria, A.; Malinow, R. NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII. Neuron, 2005, 48, 289-301. (Pubitemid 41476362)
    • (2005) Neuron , vol.48 , Issue.2 , pp. 289-301
    • Barria, A.1    Malinow, R.2
  • 71
    • 33745209672 scopus 로고    scopus 로고
    • Regulation of NR1/NR2C N-methyl-D-aspartate (NMDA) receptors by phosphorylation
    • Chen, B.S.; Braud, S.; Badger, J.D.2nd; Isaac, J.T.R.; Roche K.W. Regulation of NR1/NR2C N-methyl-D-aspartate (NMDA) receptors by phosphorylation. J. Biol. Chem., 2006, 281, 16583-16590.
    • (2006) J. Biol. Chem. , vol.281 , pp. 16583-16590
    • Chen, B.S.1    Braud, S.2    Badger II, J.D.3    Isaac, J.T.R.4    Roche, K.W.5
  • 72
    • 65649084122 scopus 로고    scopus 로고
    • Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C
    • Chen, B.S.; Roche K.W. Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C. Neuron, 2009, 62, 471-478.
    • (2009) Neuron , vol.62 , pp. 471-478
    • Chen, B.S.1    Roche, K.W.2
  • 73
    • 0033785028 scopus 로고    scopus 로고
    • The role of glycosylation in ionotropic glutamate receptor ligand binding, function, and trafficking
    • Standley, S.; Baudry, M. The role of glycosylation in ionotropic glutamate receptor ligand binding, function, and trafficking.Cell Mol Life Sci., 2000, 57, 1508-1516.
    • (2000) Cell Mol Life Sci. , vol.57 , pp. 1508-1516
    • Standley, S.1    Baudry, M.2
  • 74
    • 70350207200 scopus 로고    scopus 로고
    • Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking
    • Hayashi, T.; Thomas, G.; Huganir, R.L. Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. Neuron, 2009, 64, 213-226.
    • (2009) Neuron , vol.64 , pp. 213-226
    • Hayashi, T.1    Thomas, G.2    Huganir, R.L.3
  • 75
    • 0033995950 scopus 로고    scopus 로고
    • Molecular basis of NMDA receptor-coupled ion channel modulation by S- nitrosylation
    • DOI 10.1038/71090
    • Choi, Y.B.; Tenneti, L.; Le, D.A.; Ortiz, J.; Bai, G.; Chen H.S.V.; Lipton S.A. Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation. Nat. Neurosci., 2000, 3, 15-21. (Pubitemid 30126343)
    • (2000) Nature Neuroscience , vol.3 , Issue.1 , pp. 15-21
    • Choi, Y.-B.1    Tenneti, L.2    Le, D.A.3    Ortiz, J.4    Bai, G.5    Chen, H.-S.V.6    Lipton, S.A.7
  • 76
    • 0033793205 scopus 로고    scopus 로고
    • Redox modulation of the NMDA receptor
    • Choi ,Y.B.; Lipton, S.A. Redox modulation of the NMDA receptor. Cell Mo.l Life Sci., 2000, 57, 1535-1541.
    • (2000) Cell Mo.l Life Sci. , vol.57 , pp. 1535-1541
    • Choi, Y.B.1    Lipton, S.A.2
  • 77
    • 0035862957 scopus 로고    scopus 로고
    • 2+ modulation of the NMDA receptor
    • Choi, Y.; Chen, H.V.; Lipton, S.A. Three pairs of cysteine residues mediate both redox and Zn2+ modulation of the NMDA receptor. J. Neurosci., 2001, 21, 392-400. (Pubitemid 32107430)
    • (2001) Journal of Neuroscience , vol.21 , Issue.2 , pp. 392-400
    • Choi, Y.-B.1    Chen, H.-S.V.2    Lipton, S.A.3
  • 78
    • 8744278883 scopus 로고    scopus 로고
    • Glutamate as a therapeutic target in psychiatric disorders
    • DOI 10.1038/sj.mp.4001551
    • Javitt, D.C. Glutamate as a therapeutic target in psychiatric disorders. Mol. Psychiatry, 2004, 9, 984-997. (Pubitemid 39524288)
    • (2004) Molecular Psychiatry , vol.9 , Issue.11 , pp. 984-997
    • Javitt, D.C.1
  • 79
    • 19344374946 scopus 로고    scopus 로고
    • The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4- isoxazolyl)acetic acid
    • DOI 10.1016/j.ejphar.2004.07.049, PII S0014299904007599
    • Clausen, R.P.; Hansen, K.B.; Calí, P.; Nielsen, B.; Greenwood, J.R.; Begtrup, M.; Egebjerg, J.; Bräuner-Osborne, H. The respective Nhydroxypyrazole analogs of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. Eur. J. Pharmacol., 2004, 499, 35-44. (Pubitemid 39201209)
    • (2004) European Journal of Pharmacology , vol.499 , Issue.1-2 , pp. 35-44
    • Clausen, R.P.1    Hansen, K.B.2    Cali, P.3    Nielsen, B.4    Greenwood, J.R.5    Begtrup, M.6    Egebjerg, J.7    Brauner-Osborne, H.8
  • 80
    • 0347631873 scopus 로고
    • The excitation and depression of spinal neurones by structurally related amino acids
    • Curtis, D.R.; Watkins, J.C. The excitation and depression of spinal neurones by structurally related amino acids J. Neurochem., 1960, 6, 117-141.
    • (1960) J. Neurochem. , vol.6 , pp. 117-141
    • Curtis, D.R.1    Watkins, J.C.2
  • 81
    • 0037194828 scopus 로고    scopus 로고
    • Structural basis for understanding structure-activity relationships for the glutamate binding site of the NMDA receptor
    • DOI 10.1021/jm011091t
    • Tikhonova, I.G.; Baskin, I.I.; Palyulin, V.A.; Zefirov, N.S.; Bachurin, S.O. Structural basis for understanding structure-activity relationships for the glutamate binding site of the NMDA receptor. J. Med. Chem., 2002, 45, 3836-3843. (Pubitemid 35033449)
    • (2002) Journal of Medicinal Chemistry , vol.45 , Issue.18 , pp. 3836-3843
    • Tikhonova, I.G.1    Baskin, I.I.2    Palyulin, V.A.3    Zefirov, N.S.4    Bachurin, S.O.5
  • 83
    • 27744500994 scopus 로고    scopus 로고
    • Subunit arrangement and function in NMDA receptors
    • DOI 10.1038/nature04089, PII N04089
    • Furukawa, H.; Singh, S.K.; Mancusso, R.; Gouaux, E. Subunit arrangement and function in NMDA receptors. Nature, 2005, 438, 185-192. (Pubitemid 41599865)
    • (2005) Nature , vol.438 , Issue.7065 , pp. 185-192
    • Furukawa, H.1    Singh, S.K.2    Mancusso, R.3    Gouaux, E.4
  • 84
    • 8844247179 scopus 로고    scopus 로고
    • Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor
    • DOI 10.1016/j.neuropharm.2004.07.041, PII S0028390804002321
    • Laube, B.; Schemm, R.; Betz H. Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor. Neuropharmacol., 2004, 47, 994-1007. (Pubitemid 39535840)
    • (2004) Neuropharmacology , vol.47 , Issue.7 , pp. 994-1007
    • Laube, B.1    Schemm, R.2    Betz, H.3
  • 85
    • 17844387335 scopus 로고    scopus 로고
    • Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling
    • DOI 10.1124/mol.104.008185
    • Chen, P.E.; Geballe, M.T.; Stansfeld, P.J.; Johnston, A.R.; Yuan, H.; Jacob, A.L.; Snyder, J.P.; Traynelis, S.F.; Wyllie, D.J.A. Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling. Mol Pharmacol, 2005, 67, 1470-1484. (Pubitemid 40594146)
    • (2005) Molecular Pharmacology , vol.67 , Issue.5 , pp. 1470-1484
    • Chen, P.E.1    Geballe, M.T.2    Stansfeld, P.J.3    Johnston, A.R.4    Yuan, H.5    Jacob, A.L.6    Snyder, J.P.7    Traynelis, S.F.8    Wyllie, D.J.A.9
  • 86
    • 0025819486 scopus 로고
    • The pharmacological specificity of N-methyl-D-aspartate receptors in rat cerebral cortex: Correspondence between radioligand binding and electrophysiological measurements
    • Grimwood, S.; Foster, A.C.; Kemp, J.A. The pharmacological specificity of N-methyl-D-aspartate receptors in rat cerebral cortex: correspondence between radioligand binding and electrophysiological measurements. Br. J. Pharmacol., 1991, 103, 1385-1392
    • (1991) Br. J. Pharmacol. , vol.103 , pp. 1385-1392
    • Grimwood, S.1    Foster, A.C.2    Kemp, J.A.3
  • 89
    • 0023626743 scopus 로고
    • Excitatory amino acid receptor potency and subclass specificity of sulfur-containing amino acids
    • DOI 10.1111/j.1471-4159.1987.tb10024.x
    • Pullan, L.M.; Olney, J.W.; Price, M.T.; Compton, R.P.; Hood, W.F.; Michel, J.; Monahan, J.B. Excitatory amino acid receptor potency and subclass specificity of sulfur-containing amino acids. J. Neurochem., 1987, 49, 1301-1307. (Pubitemid 17151589)
    • (1987) Journal of Neurochemistry , vol.49 , Issue.4 , pp. 1301-1307
    • Pullan, L.M.1    Olney, J.W.2    Price, M.T.3    Compton, R.P.4    Hood, W.F.5    Michel, J.6    Monahan, J.B.7
  • 90
    • 34648827084 scopus 로고    scopus 로고
    • Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2′-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogs
    • DOI 10.1021/jm070322e
    • Pellicciari, R.; Marinozzi, M.; Macchiarulo, A.; Fulco, M.C.; Gafarova, J.; Serpi, M.; Giorgi, G.; Nielsen, S.; Thomsen, C. Synthesis, molecular modeling studies, and preliminary pharmacological characterization of all possible 2-(2'-sulfonocyclopropyl)glycine stereoisomers as conformationally constrained L-homocysteic acid analogs. J. Med. Chem., 2007, 50, 4630-4641. (Pubitemid 47463237)
    • (2007) Journal of Medicinal Chemistry , vol.50 , Issue.19 , pp. 4630-4641
    • Pellicciari, R.1    Marinozzi, M.2    Macchiarulo, A.3    Fulco, M.C.4    Gafarova, J.5    Serpi, M.6    Giorgi, G.7    Nielsen, S.8    Thomsen, C.9
  • 92
    • 0023921081 scopus 로고
    • Synthesis, resolution, and absolute configuration of the isomers of the neuronal excitant 1-amino-1,3-cyclopentanedicarboxylic acid
    • Curry, K.; Peet, M.J.; Magnuson, D.S.K.; McLennan, H. Synthesis, resolution, and absolute configuration of the isomers of the neuronal excitant l-amino-1,3-cyclopentanedicarboxylic acid. J. Med. Chem., 1988, 31, 864-867. (Pubitemid 18097111)
    • (1988) Journal of Medicinal Chemistry , vol.31 , Issue.4 , pp. 864-867
    • Curry, K.1    Peet, M.J.2    Magnuson, D.S.K.3    McLennan, H.4
  • 93
    • 0025827941 scopus 로고
    • In vitro and in vivo pharmacology of trans-and cis-(+)-1-amino-1,3- cyclopentanedicarboxylic acid: Dissociation of metabotropic and ionotropic excitatory amino acid receptor effects
    • Schoepp, D.D.; Johnson, B.G.; Salhoff, C.R.; McDonald, J.W.; Johnston, M.V. In vitro and in vivo pharmacology of trans-and cis-(+)-1-amino-1,3- cyclopentanedicarboxylic acid: dissociation of metabotropic and ionotropic excitatory amino acid receptor effects. J. Neurochem., 1991, 56, 1789-1796.
    • (1991) J. Neurochem. , vol.56 , pp. 1789-1796
    • Schoepp, D.D.1    Johnson, B.G.2    Salhoff, C.R.3    McDonald, J.W.4    Johnston, M.V.5
  • 94
    • 0025171558 scopus 로고
    • Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids
    • Allan, R.D.; Hanrahan, J.R.; Hambley, T.W.; Johnston, G.A.R.; Mewett, K.N.; Mitrovic, A.D. Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-L-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids. J. Med. Chem., 1990, 33, 2905-2915. (Pubitemid 20312163)
    • (1990) Journal of Medicinal Chemistry , vol.33 , Issue.10 , pp. 2905-2915
    • Allan, R.D.1    Hanrahan, J.R.2    Hambley, T.W.3    Johnston, G.A.R.4    Mewett, K.N.5    Mitrovic, A.D.6
  • 95
    • 0024495582 scopus 로고
    • A conformationally restricted analogue of L-glutamate, the (2S,3R,4S) isomer of L-α-(carboxycyclopropyl)glycine, activates the NMDA-type receptor more markedly than NMDA in the isolated rat spinal cord
    • DOI 10.1016/0006-8993(89)90207-2
    • Shinozaki, H.; Ishida, M.; Shimamoto, K.; Ohfune, Y. A conformationally restricted analogue of L-glutamate, the (2S,3R,4S) isomer of L-(carboxycyclopropyl)glycine, activates the NMDA-type receptor more markedly than NMDA in the isolated rat spinal cord. Brain Res., 1989, 480, 355-359. (Pubitemid 19050236)
    • (1989) Brain Research , vol.480 , Issue.1-2 , pp. 355-359
    • Shinozaki, H.1    Ishida, M.2    Shimamoto, K.3    Ohfune, Y.4
  • 96
    • 0026503073 scopus 로고
    • 2-(Carboxycyclopropyl)glycines: Binding, neurotoxicity and induction of intracellular free Ca2+ increase
    • Kawai, M.; Horikawa, Y.; Ishihara, T.; Shimamoto, K.; Ohfune, Y. 2-(Carboxycyclopropyl)glycines: binding, neurotoxicity and induction of intracellular free Ca2+ increase. Eur. J. Pharmacol., 1992, 211, 195-202.
    • (1992) Eur. J. Pharmacol. , vol.211 , pp. 195-202
    • Kawai, M.1    Horikawa, Y.2    Ishihara, T.3    Shimamoto, K.4    Ohfune, Y.5
  • 97
    • 0026756866 scopus 로고
    • Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in chinese hamster ovary cells
    • Hayashi, Y.; Tanabe, Y.; Aramori, I.; Masu, M.; Shimamoto, K.; Ohfune, Y.; Nakanishi, S. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in chinese hamster ovary cells. Br. J. Pharmacol., 1992, 107, 539-543.
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 539-543
    • Hayashi, Y.1    Tanabe, Y.2    Aramori, I.3    Masu, M.4    Shimamoto, K.5    Ohfune, Y.6    Nakanishi, S.7
  • 99
    • 0025021573 scopus 로고
    • Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors
    • DOI 10.1021/jm00163a060
    • Madsen, U.; Brehm, L.; Schaumburg, K.; Joørgensen, V.S.; Krogsgaard-Larsen, P. Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors J. Med. Chem., 1990, 33, 374-380. (Pubitemid 20038220)
    • (1990) Journal of Medicinal Chemistry , vol.33 , Issue.1 , pp. 374-380
    • Madsen, U.1    Brehm, L.2    Schaumburg, K.3    Jorgensen, F.S.4    Krogsgaard-Larsen, P.5
  • 100
    • 3242666765 scopus 로고
    • 2+-dependent mechanisms of cytotoxicity and programmed cell death
    • DOI 10.1016/0378-4274(92)90208-2
    • Orrenius, S.; McCabe, M.J.Jr.; Nicotera, P. Ca2+-dependent mechanisms of cytotoxicity and programmed cell death. Toxicol Lett, 1992, 64-65, 357-364. (Pubitemid 23018774)
    • (1992) Toxicology Letters , vol.64-65 , Issue.SPEC. ISS. , pp. 357-364
    • Orrenius, S.1    McCabe Jr., M.J.2    Nicotera, P.3
  • 101
    • 0042683081 scopus 로고    scopus 로고
    • Structure pharmacology and therapeutic prospects of family C G-protein coupled receptors
    • Brauner-Osborne, H.; Nielsen, B.; Krogsgaard-Larsen, P. Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors. Eur. J. Pharmacol., 1998, 350, 311-316.
    • (1998) Eur. J. Pharmacol. , vol.350 , pp. 311-316
    • Brauner-Osborne, H.1    Nielsen, B.2    Krogsgaard-Larsen, P.3
  • 103
    • 0037127757 scopus 로고    scopus 로고
    • Synthesis of 1-hydroxypyrazole glycine derivatives
    • DOI 10.1016/S0040-4020(02)00021-2, PII S0040402002000212
    • Calí, P.; Begtrup, M. Synthesis of 1-hydroxypyrazole glycine derivatives Tetrahedron, 2002, 58, 1595-1605. (Pubitemid 34173029)
    • (2002) Tetrahedron , vol.58 , Issue.8 , pp. 1595-1605
    • Cali, P.1    Begtrup, M.2
  • 107
    • 0030024147 scopus 로고    scopus 로고
    • N-Methyl-D-aspartic acid receptor agonists: Resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5- methyl-4-isoxazolyl)acetic acid
    • Madsen, U.; Frydenvang, K.; Ebert, B.; Johansen, T.N.; Brehm, L.; Krogsgaard-Larsen, P. N-Methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. J. Med. Chem., 1996, 39, 183-190.
    • (1996) J. Med. Chem. , vol.39 , pp. 183-190
    • Madsen, U.1    Frydenvang, K.2    Ebert, B.3    Johansen, T.N.4    Brehm, L.5    Krogsgaard-Larsen, P.6
  • 110
    • 33847273693 scopus 로고    scopus 로고
    • Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation
    • DOI 10.1074/jbc.M608156200
    • Maier, W.; Schemm, R.; Grewer, C.; Laube, B. Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation. J. Biol. Chem., 2007, 282, 1863-1872. (Pubitemid 47076721)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.3 , pp. 1863-1872
    • Maier, W.1    Schemm, R.2    Grewer, C.3    Laube, B.4
  • 111
    • 78650286113 scopus 로고    scopus 로고
    • Partial agonists and subunitselectivity at NMDA receptors
    • Risgaard, R.; Hansen, K.B.; Clausen, R.P. Partial agonists and subunitselectivity at NMDA receptors Chem. Eur. J., 2010, 16, 13910-13918.
    • (2010) Chem. Eur. J. , vol.16 , pp. 13910-13918
    • Risgaard, R.1    Hansen, K.B.2    Clausen, R.P.3
  • 112
    • 77952721574 scopus 로고    scopus 로고
    • 4-Hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologs
    • Lolli, M.L.; Giordano, C.; Pickering, D.S.; Rolando, B.; Hansen, K.B.; Foti, A.; Contreras-Sanz, A.; Amir, A.; Fruttero, R.; Gasco, A.; Nielsen, B.; Johansen, T.N. 4-Hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologs. J. Med. Chem., 2010, 53, 4110-4118.
    • (2010) J. Med. Chem. , vol.53 , pp. 4110-4118
    • Lolli, M.L.1    Giordano, C.2    Pickering, D.S.3    Rolando, B.4    Hansen, K.B.5    Foti, A.6    Contreras-Sanz, A.7    Amir, A.8    Fruttero, R.9    Gasco, A.10    Nielsen, B.11    Johansen, T.N.12
  • 113
    • 0000810878 scopus 로고
    • Constituents of indigenous fungi I. Isolation of the insecticidal constituent from Tricholoma muscarium
    • Takemoto, T.; Nakajima, T. Constituents of indigenous fungi I. Isolation of the insecticidal constituent from Tricholoma muscarium. J. Pharm. Soc. Jpn., 1964, 84, 1183-1186.
    • (1964) J. Pharm. Soc. Jpn. , vol.84 , pp. 1183-1186
    • Takemoto, T.1    Nakajima, T.2
  • 114
    • 0000810877 scopus 로고
    • Studies on the constituents of indogenous fungi. II. Isolation of the flycidal constituent from
    • Takemoto, T.; Yokobe, T.; Nakajima, T. Studies on the constituents of indogenous fungi. II. Isolation of the flycidal constituent from Amanita Strobiliformis. J. Pharm. Soc. Jpn., 1964, 84, 1186-1188.
    • (1964) Amanita Strobiliformis. J. Pharm. Soc. Jpn. , vol.84 , pp. 1186-1188
    • Takemoto, T.1    Yokobe, T.2    Nakajima, T.3
  • 116
    • 33846798154 scopus 로고    scopus 로고
    • Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof
    • DOI 10.1016/j.tet.2006.12.066, PII S0040402006020357
    • Conti, P.; De Amici, M.; Roda, G.; Pinto, A.; Tamborini, L.; Madsen, U.; Nielsen, B.; Bräuner-Osborne, H.; De Micheli, C. Synthesis and pharmacological characterization at glutamate receptors of erythro-and threo-tricholomic acid and homologs thereof. Tetrahedron, 2007, 63, 2249-2256. (Pubitemid 46201690)
    • (2007) Tetrahedron , vol.63 , Issue.10 , pp. 2249-2256
    • Conti, P.1    De Amici, M.2    Roda, G.3    Pinto, A.4    Tamborini, L.5    Madsen, U.6    Nielsen, B.7    Brauner-Osborne, H.8    De Micheli, C.9
  • 119
    • 0342468278 scopus 로고    scopus 로고
    • The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits
    • DOI 10.1016/0197-0186(95)00091-7
    • De Carvalho, L.P.; Bochet, P.; Rossier, J. The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem. Int., 1996, 28, 445-452. (Pubitemid 26120215)
    • (1996) Neurochemistry International , vol.28 , Issue.4 , pp. 445-452
    • Prado De Carvalho, L.1    Bochet, P.2    Rossier, J.3
  • 120
    • 23944453392 scopus 로고    scopus 로고
    • Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog
    • DOI 10.1523/JNEUROSCI.1613-05.2005
    • Erreger, K.; Geballe, M.T.; Dravid, S.M.; Snyder, J.P.; Wyllie, D.J.A.; Traynelis, S.F. Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog. J. Neurosci., 2005, 25, 7858-7866. (Pubitemid 41208658)
    • (2005) Journal of Neuroscience , vol.25 , Issue.34 , pp. 7858-7866
    • Erreger, K.1    Geballe, M.T.2    Dravid, S.M.3    Snyder, J.P.4    Wyllie, D.J.A.5    Traynelis, S.F.6
  • 121
    • 0033360848 scopus 로고    scopus 로고
    • Analogs of a superacidic NMDA receptor agonist, N-phthalamoyl-L-glutamic acid (PhGA): Activity and mode of interaction with the receptor recognition site
    • Zhenochin, S.P.; Piotrovsky, L.B.; Dumpis, M.A.; Maximyuk, P.; Lishko, P.V.; Tsyndrenko, AYa.; Krishtal, O.A. Analogs of a superacidic NMDA receptor agonist, N-phthalamoyl-L-glutamic acid (PhGA): activity and mode of interaction with the receptor recognition site Neurophysiology, 1999, 31, 359-369.
    • (1999) Neurophysiology , vol.31 , pp. 359-369
    • Zhenochin, S.P.1    Piotrovsky, L.B.2    Dumpis, M.A.3    Maximyuk, P.4    Lishko, P.V.5    Tsyndrenko, A.Ya.6    Krishtal, O.A.7
  • 123
    • 34249840221 scopus 로고
    • Effect of N-phthalamoyl-L-glutamic acid, a selective NMDA receptor agonist, on binding of 3H-L-glutamate with hippocampal synaptic membranes
    • Koreshonkov, O.N.; Perestenko, P.V.; Dumpis, M.A.; Piotrovskii, L.B. Effect of N-phthalamoyl-L-glutamic acid, a selective NMDA receptor agonist, on binding of 3H-L-glutamate with hippocampal synaptic membranes. Bull. Exp. Biol. Med., 1992, 113, 749-751.
    • (1992) Bull. Exp. Biol. Med. , vol.113 , pp. 749-751
    • Koreshonkov, O.N.1    Perestenko, P.V.2    Dumpis, M.A.3    Piotrovskii, L.B.4
  • 124
    • 0031004214 scopus 로고    scopus 로고
    • Dysiherbaine: A new neurotoxic amino acid from the Micronesian marine sponge Dysidea herbacea
    • DOI 10.1021/ja963953z
    • Sakai, R.; Kamiya, H.; Murata, M.; Shimamoto, K. Dysiherbaine: a new neurotoxic amino acid from the micronesian marine sponge Dysidea herbacea. J. Am. Chem. Soc., 1997, 119, 4112-4116. (Pubitemid 27239959)
    • (1997) Journal of the American Chemical Society , vol.119 , Issue.18 , pp. 4112-4116
    • Sakai, R.1    Kamiya, H.2    Murata, M.3    Shimamoto, K.4
  • 125
    • 0037118264 scopus 로고    scopus 로고
    • Differential activation of individual subunits in heteromeric kainate receptors
    • DOI 10.1016/S0896-6273(02)00676-1
    • Swanson, G.T.; Green, T.; Sakai, R.; Contractor, A.; Che, W.; Kamiya, H.; Heinemann, S.F. Differential activation of individual subunits in heteromeric kainate receptors. Neuron, 2002, 34, 589-598. (Pubitemid 34628755)
    • (2002) Neuron , vol.34 , Issue.4 , pp. 589-598
    • Swanson, G.T.1    Green, T.2    Sakai, R.3    Contractor, A.4    Che, W.5    Kamiya, H.6    Heinemann, S.F.7
  • 126
    • 33644804186 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine
    • DOI 10.1016/j.bmcl.2006.01.047, PII S0960894X06000849
    • Cohen, J.L.; Limon, A.; Miledi, R.; Chamberlin, A.R. Design, synthesis, and biological evaluation of a scaffold for iGluR ligands based on the structure of (-)-dysiherbaine. Bioorg. Med. Chem. Lett., 2006, 16, 2189-2194. (Pubitemid 43351076)
    • (2006) Bioorganic and Medicinal Chemistry Letters , vol.16 , Issue.8 , pp. 2189-2194
    • Cohen, J.L.1    Limon, A.2    Miledi, R.3    Chamberlin, A.R.4
  • 127
    • 30844439634 scopus 로고    scopus 로고
    • Glutamate-based therapeutic approaches: Clinical trials with NMDA antagonists
    • Muir, K.W. Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists. Curr. Opin. Pharmacol., 2007, 6, 53-60.
    • (2007) Curr. Opin. Pharmacol. , vol.6 , pp. 53-60
    • Muir, K.W.1
  • 128
    • 0026685127 scopus 로고
    • Modeling of competitive phosphono amino acid NMDA receptor antagonists
    • Whitten, J.P.; Harrison, B.L.; Weintraub, H.J.R.; McDonald, I.A. Modeling of competitive phosphono amino acid NMDA receptor antagonists. J. Med. Chem., 1992, 35, 1509-1514.
    • (1992) J. Med. Chem. , vol.35 , pp. 1509-1514
    • Whitten, J.P.1    Harrison, B.L.2    Weintraub, H.J.R.3    McDonald, I.A.4
  • 130
    • 0035577313 scopus 로고    scopus 로고
    • NMDA receptor antagonists as analgesics: Focus on the NR2B subtype
    • Chizh, B.A.; Headley, P.M.; Tzschentke, T.M. NMDA receptor antagonists as analgesics: focus on the NR2B subtype. Trends Pharmacol. Sci., 2001, 22, 636-641.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 636-641
    • Chizh, B.A.1    Headley, P.M.2    Tzschentke, T.M.3
  • 131
    • 55749108180 scopus 로고    scopus 로고
    • Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance
    • Chen, M.; Lu, T.J.; Chen, X.J.; Zhou, Y.; Chen, Q.; Feng, X.Y.; Xu, L.; Duan, W.H.; Xiong, Z.Q. Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance. Stroke, 2008, 39, 3042-3048.
    • (2008) Stroke , vol.39 , pp. 3042-3048
    • Chen, M.1    Lu, T.J.2    Chen, X.J.3    Zhou, Y.4    Chen, Q.5    Feng, X.Y.6    Xu, L.7    Duan, W.H.8    Xiong, Z.Q.9
  • 132
    • 2542431131 scopus 로고    scopus 로고
    • Rationale for and use of NMDA receptor antagonists in Parkinson's disease
    • DOI 10.1016/j.pharmthera.2004.04.001, PII S016372580400049X
    • Hallett, P.J.; Standaert, D.G. Rationale for and use of NMDA receptor antagonists in Parkinson's disease. Pharmacol. Ther., 2004, 102, 155-174. (Pubitemid 38681014)
    • (2004) Pharmacology and Therapeutics , vol.102 , Issue.2 , pp. 155-174
    • Hallett, P.J.1    Standaert, D.G.2
  • 133
    • 0034793826 scopus 로고    scopus 로고
    • Differential effects of enrichment on learning and memory function in NR2B transgenic mice
    • DOI 10.1016/S0028-3908(01)00122-8, PII S0028390801001228
    • Tang, Y.P.; Wang, H.; Feng, R.; Kyin, M.; Tsien, J.Z. Differential effects of enrichment on learning and memory function in NR2B transgenic mice. Neuropharmacol., 2001, 41, 779-790. (Pubitemid 32972196)
    • (2001) Neuropharmacology , vol.41 , Issue.6 , pp. 779-790
    • Tang, Y.-P.1    Wang, H.2    Feng, R.3    Kyin, M.4    Tsien, J.Z.5
  • 134
    • 64949130758 scopus 로고    scopus 로고
    • Plasticity of NMDA receptor NR2B subunit in memory and chronic pain
    • Zhuo, M. Plasticity of NMDA receptor NR2B subunit in memory and chronic pain. Mol. Brain, 2009, 2: 4.
    • (2009) Mol. Brain , vol.2 , pp. 4
    • Zhuo, M.1
  • 135
    • 0018609344 scopus 로고
    • Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog
    • Evans, R.H.; Francis, A.A.; Hunt, K.; Oakes, D.J.; Watkins, J.C. Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. Br. J. Pharmacol., 1979, 67, 591-603. (Pubitemid 10129086)
    • (1979) British Journal of Pharmacology , vol.67 , Issue.4 , pp. 591-603
    • Evans, R.H.1    Francis, A.A.2    Hunt, K.3
  • 138
    • 0037656649 scopus 로고    scopus 로고
    • Competitive NMDA antagonists - A comprehensive analysis of molecular biological, structure activity and molecular modeling relationships
    • Johnson, G.; Ornstein, P.L. Competitive NMDA antagonists -A comprehensive analysis of molecular biological, structure activity and molecular modeling relationships. Curr. Pharm. Des., 1996, 2, 331-356. (Pubitemid 126475038)
    • (1996) Current Pharmaceutical Design , vol.2 , Issue.4 , pp. 331-356
    • Johnson, G.1    Ornstein, P.L.2
  • 140
    • 0025076313 scopus 로고
    • New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation
    • Hays, S.J.; Bigge, C.F.; Novak, P.M.; Drummond, J.T.; Bobovski, T.P.; Rice, M.J.; Johnson, G.; Brahce, L.J.; Coughenour, L.L. New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure activity relationships and pharmacological evaluation J. Med. Chem., 1990, 33, 2916-2924. (Pubitemid 20312164)
    • (1990) Journal of Medicinal Chemistry , vol.33 , Issue.10 , pp. 2916-2924
    • Hays, S.J.1    Bigge, C.F.2    Novak, P.M.3    Drummond, J.T.4    Bobovski, T.P.5    Rice, M.J.6    Johnson, G.7    Brahce, L.J.8    Coughenour, L.L.9
  • 141
    • 0023152733 scopus 로고
    • CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: Characterization in vitro and in vivo
    • Lehmann, J.; Schneider, J.; McPherson, S.; Murphy, D.E.; Bernard, P.; Tsai, C.; Bennett, D.A.; Pastor, G.; Steel, D.J.; Boehm, C. CPP, a selective Nmethyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo. J. Pharmacol. Exp. Ther., 1987, 240, 737-746. (Pubitemid 17043569)
    • (1987) Journal of Pharmacology and Experimental Therapeutics , vol.240 , Issue.3 , pp. 737-746
    • Lehmann, J.1    Schneider, J.2    McPherson, S.3
  • 142
    • 0024349541 scopus 로고
    • Synthesis and NMDA antagonistic properties of the enantiomers of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-phosphonoprop-2-enyl)piperazine-2-carboxylic acid (CPP-ene)
    • Aebischer, B.; Frey, P.; Haerter H.P.; Herrling, P.L.; Mueller, W.; Olverman, H.J.; Watkins, J.C. Synthesis and NMDA antagonist properties of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-phosphonoprop-2-enyl)piperazine-2-carboxylic acid (CPP-ene). Helv. Chim. Acta, 1989, 72, 1043-1051. (Pubitemid 19203027)
    • (1989) Helvetica Chimica Acta , vol.72 , Issue.5 , pp. 1043-1051
    • Aebischer, B.1    Frey, P.2    Haerter, H.-P.3    Herrling, P.L.4    Mueller, W.5    Olverman, H.J.6    Watkins, J.C.7
  • 148
    • 0026581612 scopus 로고
    • Synthesis and N-methyl-D-aspartate (NMDA) antagonist properties of the enantiomers of-amino-5-(phosphonomethyl)[1,1-biphenyl]-3-propanoic acid. Use of a new chiral glycine derivative
    • Mueller, W.; Lowe, D.A.; Neijt, H.; Urwyler, S.; Herrling, P.L.; Blaser, D.; Seebach D. Synthesis and N-methyl-D-aspartate (NMDA) antagonist properties of the enantiomers of amino-5-(phosphonomethyl)[1,1-biphenyl]-3-propanoic acid. Use of a new chiral glycine derivative. Helv. Chim. Acta, 1992, 75, 855-864.
    • (1992) Helv. Chim. Acta , vol.75 , pp. 855-864
    • Mueller, W.1    Lowe, D.A.2    Neijt, H.3    Urwyler, S.4    Herrling, P.L.5    Blaser, D.6    Seebach, D.7
  • 150
    • 0025979690 scopus 로고
    • 4-(Tetrazoleylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action
    • Elzey, T. 4-(Tetrazoleylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action. J. Med. Chem., 1991, 34, 90-97.
    • (1991) J. Med. Chem. , vol.34 , pp. 90-97
    • Elzey, T.1
  • 151
    • 0025677185 scopus 로고
    • Pharmacological characterization of LY233053: A structurally novel tetrazolee-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action
    • Schoepp, D.D.; Ornstein, P.L.; Leander, J.D.; Lodge, D.; Salhoff, C.R.; Zeman, S.; Zimmerman, D.M. Pharmacological characterization of LY233053: a structurally novel tetrazolee-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action. J. Pharmacol. Exp. Ther., 1990, 255, 1301-1308.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 1301-1308
    • Schoepp, D.D.1    Ornstein, P.L.2    Leander, J.D.3    Lodge, D.4    Salhoff, C.R.5    Zeman, S.6    Zimmerman, D.M.7
  • 152
    • 0026761469 scopus 로고
    • NMDA antagonist activity of (+)-(2SR,4RS)-4-(1H-tetrazole-5-ylmethyl) piperidine-2-carboxylic acid resides with the (-)-2R,4S-isomer
    • Ornstein, P.L.; Schoepp, D.D.; Arnold, M.B.; Jones, N.D.; Deeter, J.B.; Lodge, D.; Leander, J.D. NMDA antagonist activity of (+)-(2SR,4RS)-4-(1H- tetrazole-5-ylmethyl)piperidine-2-carboxylic acid resides with the (-)-2R,4S-isomer J. Med. Chem., 1992, 35, 3111-3115.
    • (1992) J. Med. Chem. , vol.35 , pp. 3111-3115
    • Ornstein, P.L.1    Schoepp, D.D.2    Arnold, M.B.3    Jones, N.D.4    Deeter, J.B.5    Lodge, D.6    Leander, J.D.7
  • 153
    • 13844253597 scopus 로고    scopus 로고
    • The effect of competitive antagonist chain length on NMDA receptor subunit selectivity
    • DOI 10.1016/j.neuropharm.2004.11.004
    • Feng, B.; Morley, R.M.; Jane, D. E.; Monaghan, D.T. The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacol., 2005, 48, 354-359. (Pubitemid 40249998)
    • (2005) Neuropharmacology , vol.48 , Issue.3 , pp. 354-359
    • Feng, B.1    Morley, R.M.2    Jane, D.E.3    Monaghan, D.T.4
  • 154
    • 19444366505 scopus 로고    scopus 로고
    • Identification of subunit-specific and antagonist specific amino acids in the NMDA receptor glutamate binding pocket
    • Kinarsky, L.; Feng, B.; Skifter, D.; Morley, R.M.; Sherman, S.; Jane, D.E.; Monaghan, D.T. Identification of subunit-specific and antagonist specific amino acids in the NMDA receptor glutamate binding pocket. J. Pharmacol. Exp. Ther., 2005, 313, 1066-1074.
    • (2005) J. Pharmacol. Exp. Ther. , vol.313 , pp. 1066-1074
    • Kinarsky, L.1    Feng, B.2    Skifter, D.3    Morley, R.M.4    Sherman, S.5    Jane, D.E.6    Monaghan, D.T.7
  • 155
    • 29244446841 scopus 로고    scopus 로고
    • Comparative analysis of different competitive antagonists interaction with NR2A and NR2B subunits of N-methyl-D-aspartate (NMDA) ionotropic glutamate receptor
    • DOI 10.1007/s00894-005-0258-5
    • Blaise, M.C.; Sowdhamini, R.; Pradhan, N. Comparative analysis of different competitive antagonists interaction with NR2A and NR2B subunits of Nmethyl-D-aspartate (NMDA) ionotropic glutamate receptor. J. Mol. Model., 2005, 11, 489-502. (Pubitemid 41829671)
    • (2005) Journal of Molecular Modeling , vol.11 , Issue.6 , pp. 489-502
    • Blaise, M.-C.1    Sowdhamini, R.2    Pradhan, N.3
  • 156
    • 24044454692 scopus 로고    scopus 로고
    • Development of a three-dimensional model for the N-methyl-D-aspartate NR2A subunit
    • DOI 10.1021/jm050174x
    • Grazioso, G.; Moretti, L.; Scapozza, L.; De Amici, M.; De Micheli, C. Development of a three-dimensional model for the N-methyl-D-aspartate NR2A subunit. J. Med. Chem., 2005, 48, 5489-5494. (Pubitemid 41213350)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.17 , pp. 5489-5494
    • Grazioso, G.1    Moretti, L.2    Scapozza, L.3    De Amici, M.4    De Micheli, C.5
  • 157
    • 0034009242 scopus 로고    scopus 로고
    • Native N-methyl-D-aspartate receptors containing NR2A and NR2B subunits have pharmacologically distinct competitive antagonist binding sites
    • Christie, J.M.; Jane, D.E; Monaghan, D.T. Native N-methyl-D-aspartate receptors containing NR2A and NR2B subunits have pharmacologically distinct competitive antagonist binding sites. J. Pharmacol. Exp. Ther., 2000, 292, 1169-1174. (Pubitemid 30136615)
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.292 , Issue.3 , pp. 1169-1174
    • Christie, J.M.1    Jane, D.E.2    Monaghan, D.T.3
  • 158
    • 65249119706 scopus 로고    scopus 로고
    • Ligands for ionotropic glutamate receptors
    • Swanson, G.T.; Sakai, R. Ligands for ionotropic glutamate receptors. Prog. Mol. Subcell. Biol., 2009, 46, 123-157.
    • (2009) Prog. Mol. Subcell. Biol. , vol.46 , pp. 123-157
    • Swanson, G.T.1    Sakai, R.2
  • 159
    • 34249010244 scopus 로고    scopus 로고
    • The molecular basis of Conantokin antagonism of NMDA receptor function
    • DOI 10.2174/138945007780618481
    • Prorok, M.; Castellino, F.J. The molecular basis of conantokin antagonism of NMDA receptor function. Curr. Drug Targets, 2007, 8, 633-642. (Pubitemid 46785061)
    • (2007) Current Drug Targets , vol.8 , Issue.5 , pp. 633-642
    • Prorok, M.1    Castellino, F.J.2
  • 161
    • 9144236304 scopus 로고    scopus 로고
    • Conantokins: Peptide antagonists of NMDA receptors
    • Layer, R.T.; Wagstaff, J.D.; White, H.S. Conantokins: peptide antagonists of NMDA receptors. Curr. Med. Chem., 2004, 11, 3073-3084. (Pubitemid 39545576)
    • (2004) Current Medicinal Chemistry , vol.11 , Issue.23 , pp. 3073-3084
    • Layer, R.T.1    Wagstaff, J.D.2    White, H.S.3
  • 162
    • 58549085757 scopus 로고    scopus 로고
    • Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain
    • Hama, A.; Sagen, J. Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain. Neuropharmacol., 2009, 56, 556-563.
    • (2009) Neuropharmacol. , vol.56 , pp. 556-563
    • Hama, A.1    Sagen, J.2
  • 163
    • 37549069739 scopus 로고    scopus 로고
    • Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors
    • Teichert, R.W.; Jimenez, E.C.; Twede, V.; Watkins, M.; Hollmann, M.; Bulaj, G.; Olivera, B.M. Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors. J. Biol. Chem., 2007, 282, 36905-36913.
    • (2007) J. Biol. Chem. , vol.282 , pp. 36905-36913
    • Teichert, R.W.1    Jimenez, E.C.2    Twede, V.3    Watkins, M.4    Hollmann, M.5    Bulaj, G.6    Olivera, B.M.7
  • 164
  • 165
    • 0035920125 scopus 로고    scopus 로고
    • The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors
    • Klein, R.C.; Prorok, M.; Galdzicki, Z.; Castellino, F.J. The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors. J. Biol. Chem., 2001, 276, 26860-26867.
    • (2001) J. Biol. Chem. , vol.276 , pp. 26860-26867
    • Klein, R.C.1    Prorok, M.2    Galdzicki, Z.3    Castellino, F.J.4
  • 166
    • 34547211472 scopus 로고    scopus 로고
    • Subtype-selective antagonism of N-methyl-d-aspartate receptor ion channels by synthetic conantokin peptides
    • DOI 10.1016/j.neuropharm.2007.04.016, PII S0028390807001244
    • Sheng, Z.; Dai, Q.; Prorok, M.; Castellino, F.J. Subtype-selective antagonism of N-methyl-D-aspartate receptor ion channels by synthetic conantokin peptides. Neuropharmacol., 2007, 53, 145-156. (Pubitemid 47125955)
    • (2007) Neuropharmacology , vol.53 , Issue.1 , pp. 145-156
    • Sheng, Z.1    Dai, Q.2    Prorok, M.3    Castellino, F.J.4
  • 167
    • 0031046379 scopus 로고    scopus 로고
    • Pharmacological heterogeneity of NMDA receptors: Characterization of NR1a/NR2D heteromers expressed in Xenopus oocytes
    • DOI 10.1016/S0014-2999(96)00880-1, PII S0014299996008801
    • Buller, A.L.; Monaghan, D.T. Pharmacological heterogeneity of NMDA receptors: characterization of NR1a/NR2D heteromers expressed in Xenopus oocytes. Eur. J. Pharmacol., 1997, 320, 87-94. (Pubitemid 27076261)
    • (1997) European Journal of Pharmacology , vol.320 , Issue.1 , pp. 87-94
    • Buller, A.L.1    Monaghan, D.T.2
  • 168
    • 1542269774 scopus 로고    scopus 로고
    • Structure - Activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid
    • DOI 10.1038/sj.bjp.0705644
    • Feng, B.; Tse, H.W.; Skifter, D.A.; Morley, R.; Jane, D.E.; Monaghan, D.T. Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid. Br. J. Pharmacol., 2004, 141, 508-516. (Pubitemid 38297013)
    • (2004) British Journal of Pharmacology , vol.141 , Issue.3 , pp. 508-516
    • Feng, B.1    Tse, H.W.2    Skifter, D.A.3    Morley, R.4    Jane, D.E.5    Monaghan, D.T.6
  • 169
    • 17144378207 scopus 로고    scopus 로고
    • 1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists
    • DOI 10.1021/jm0492498
    • Morley, R.M.; Tse, H.W.; Feng, B.; Miller, J.C.; Monaghan, D.T.; Jane, D.E. Synthesis and pharmacology of N1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists. J. Med. Chem., 2005, 48, 2627-2637. (Pubitemid 40516452)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.7 , pp. 2627-2637
    • Morley, R.M.1    Tse, H.-W.2    Feng, B.3    Miller, J.C.4    Monaghan, D.T.5    Jane, D.E.6
  • 170
    • 0026681096 scopus 로고
    • Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists
    • Ortwine, D.F.; Malone, T.C.; Bigge, C.F.; Drummond , J.T.; Humblet, C.; Johnson, G.; Pinter, G.W. Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists. J. Med. Chem., 1992, 35, 1345-1370.
    • (1992) J. Med. Chem. , vol.35 , pp. 1345-1370
    • Ortwine, D.F.1    Malone, T.C.2    Bigge, C.F.3    Drummond, J.T.4    Humblet, C.5    Johnson, G.6    Pinter, G.W.7
  • 172
    • 0004214862 scopus 로고
    • Kozikowski, A.P. Ed.; Raven Press, Ltd.: N.Y
    • Ornstein, P.L. In: Drug Design for Neuroscience; Kozikowski, A.P. Ed.; Raven Press, Ltd.: N.Y., 1993; pp 285-309.
    • (1993) Drug Design for Neuroscience , pp. 285-309
    • Ornstein, P.L.1
  • 174
    • 0029001397 scopus 로고
    • Orally active, competitive N-methyl-D-aspartate (NMDA) receptor antagonists are substrates for a neutral amino acid uptake system in chinese hamster ovary cells
    • Li, J.H.; Bigge, C.F.; Williamson, R.M.; Borosky, S.A.; Vartanian, M.G.; Ortwine, D.F. Potent, orally active, competitive N-methyl-D-aspartate (NMDA) receptor antagonists are substrates for a neutral amino acid uptake system in chinese hamster ovary cells. J. Med. Chem., 1995, 38,1955-1965.
    • (1995) J. Med. Chem. , vol.38 , pp. 1955-1965
    • Li, J.H.1    Bigge, C.F.2    Williamson, R.M.3    Borosky, S.A.4    Vartanian, M.G.5    Potent, F.O.D.6
  • 175
    • 0026597447 scopus 로고
    • Characterization of 3-carboxy-5-phosphono-1,2,3,4-tetrahydroisoquinoline (SC-48981), a potent competitive N-methy-D-aspartate (NMDA) receptor antagonist, in vitro and in vivo
    • Vazquez, M.L.; Garland, D.J.; Sun, E.T.; Cler, J.A.; Mick, S.J.; Hood, W.F.; Monahan, J.B.; Iyengar, S.; Rao, T.S. Characterization of 3-carboxy-5-phosphono-1,2,3,4-tetrahydroisoquinoline (SC-48981), a potent competitive N-methy-D-aspartate (NMDA) receptor antagonist, in vitro and in vivo. Neurosci. Lett., 1992, 135, 149-152.
    • (1992) Neurosci. Lett. , vol.135 , pp. 149-152
    • Vazquez, M.L.1    Garland, D.J.2    Sun, E.T.3    Cler, J.A.4    Mick, S.J.5    Hood, W.F.6    Monahan, J.B.7    Iyengar, S.8    Rao, T.S.9
  • 178
    • 0025923854 scopus 로고
    • Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA antagonist
    • Schoepp, D.D.; Ornstein, P.L.; Salhoff, C.R.; Leander, J.D. Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA antagonist. J. Neural. Trasm., 1991, 85, 131-143.
    • (1991) J. Neural. Trasm. , vol.85 , pp. 131-143
    • Schoepp, D.D.1    Ornstein, P.L.2    Salhoff, C.R.3    Leander, J.D.4
  • 179
    • 0037041183 scopus 로고    scopus 로고
    • 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition
    • DOI 10.1016/S0960-894X(02)00074-4, PII S0960894X02000744
    • Auberson, Y.P.; Allgeier, H.; Bischoff, S.; Lingenhoehl, K.; Moretti, R.; Schmutz, M. 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg. Med. Chem. Lett., 2002, 12, 1099-1102. (Pubitemid 34242811)
    • (2002) Bioorganic and Medicinal Chemistry Letters , vol.12 , Issue.7 , pp. 1099-1102
    • Auberson, Y.P.1    Allgeier, H.2    Bischoff, S.3    Lingenhoehl, K.4    Moretti, R.5    Schmutz, M.6
  • 180
    • 0020336555 scopus 로고
    • 3H]AMPA, a structural analogue of glutamic acid, to rat brain membranes
    • Honoré, T.; Lauridsen, J.; Krogsgaard-Larsen, P. The binding of [3H]AMPA, a structural analogue of glutamic acid, to rat brain membranes. Neurochem., 1982, 38, 173-178. (Pubitemid 12189209)
    • (1982) Journal of Neurochemistry , vol.38 , Issue.1 , pp. 173-178
    • Honore, T.1    Lauridsen, J.2    Krogsgaard-Larsen, P.3
  • 181
    • 0030302457 scopus 로고    scopus 로고
    • [3H] MDL 105,519, a high-affinity radioligand for the N-methyl-Daspartate receptor-associated glycine recognition site
    • Baron, B.M.; Siegel, B.W.; Harrison, B.L.; Gross, R.S.; Hawes, C.; Towers, P. [3H]MDL 105,519, a high-affinity radioligand for the N-methyl-Daspartate receptor-associated glycine recognition site. J. Pharmacol. Exp. Ther., 1996, 279, 62-68.
    • (1996) J. Pharmacol. Exp. Ther. , vol.279 , pp. 62-68
    • Baron, B.M.1    Siegel, B.W.2    Harrison, B.L.3    Gross, R.S.4    Hawes, C.5    Towers, P.6
  • 182
    • 2342637165 scopus 로고    scopus 로고
    • Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity
    • DOI 10.1126/science.1096615
    • Liu, L.; Wong, T.P.; Pozza, M.F.; Lingenhoehl, K.; Wang, Y.; Sheng, M.; Auberson, Y.P.; Wang, Y.T. Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science, 2004, 304, 1021-1024. (Pubitemid 38638102)
    • (2004) Science , vol.304 , Issue.5673 , pp. 1021-1024
    • Liu, L.1    Wong, T.P.2    Pozza, M.F.3    Lingenhoehl, K.4    Wang, Y.5    Sheng, M.6    Auberson, Y.P.7    Wang, Y.T.8
  • 183
    • 4544373236 scopus 로고    scopus 로고
    • Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression
    • DOI 10.1523/JNEUROSCI.1697-04.2004
    • Massey, P.V.; Johnson, B.E.; Moult, P.R.; Auberson Y.P.; Brown, M.W.; Molnar, E.; Collingridge, G.L.; Bashir, Z.I. Differential roles of NR2A and NR2B-containing NMDA receptors in. cortical long-term potentiation and long-term depression. J. Neurosci., 2004, 24, 7821-7828. (Pubitemid 39215685)
    • (2004) Journal of Neuroscience , vol.24 , Issue.36 , pp. 7821-7828
    • Massey, P.V.1    Johnson, B.E.2    Moult, P.R.3    Auberson, Y.P.4    Brown, M.W.5    Molnar, E.6    Collingridge, G.L.7    Bashir, Z.I.8
  • 184
    • 33645010267 scopus 로고    scopus 로고
    • Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors
    • Zhou, M.; Baudry, M. Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors. J. Neurosci., 2006, 26, 2956-2963.
    • (2006) J. Neurosci. , vol.26 , pp. 2956-2963
    • Zhou, M.1    Baudry, M.2
  • 185
    • 33747598487 scopus 로고    scopus 로고
    • Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3- dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B N-methyl-D-aspartate receptors: Implications for studies of synaptic transmission
    • DOI 10.1124/mol.106.024042
    • Frizelle, P.A.; Chen, P.E.; Wyllie, D.J.A Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin- 5-yl)-methyl]-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B NMDA receptors: implications for studies of synaptic transmission. Mol. Pharmacol., 2006, 70, 1022-1032. (Pubitemid 44268459)
    • (2006) Molecular Pharmacology , vol.70 , Issue.3 , pp. 1022-1032
    • Frizelle, P.A.1    Chen, P.E.2    Wyllie, D.J.A.3
  • 186
    • 32544450453 scopus 로고    scopus 로고
    • Relating NMDA receptor function to receptor subunit composition: Limitations of the pharmacological approach
    • DOI 10.1523/JNEUROSCI.5242-05.2006
    • Neyton, J.; Paoletti, P. Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach. J. Neurosci., 2006, 26, 1331-1333. (Pubitemid 43237003)
    • (2006) Journal of Neuroscience , vol.26 , Issue.5 , pp. 1331-1333
    • Neyton, J.1    Paoletti, P.2
  • 189
    • 0000741608 scopus 로고    scopus 로고
    • Bicyclo[1.1.1] pentanes, [n]staffanes, [1.1.1]propellanes, and tricyclo[2.1.0.02,5]pentanes
    • Levin, M.D.; Kaszynsky, P.; Michl, J. Bicyclo[1.1.1]pentanes, [n]staffanes, [1.1.1]propellanes, and tricyclo[2.1.0.02,5]pentanes. Chem. Rev., 2000, 100, 169-234.
    • (2000) Chem. Rev. , vol.100 , pp. 169-234
    • Levin, M.D.1    Kaszynsky, P.2    Michl, J.3
  • 190
    • 34249029333 scopus 로고    scopus 로고
    • Synthesis of a chiral amino acid with bicyclo[1.1.1] pentane moiety and its incorporation into linear and cyclic antimicrobial peptides
    • DOI 10.1039/b702134h
    • Pritz, S.; Pätzel, M.; Szeimies, G.; Dathe, M.; Bienert, M. Synthesis of a chiral amino acid with bicyclo[1.1.1]pentane moiety and its incorporation into linear and cyclic antimicrobial peptides. Org. Biomol. Chem., 2007, 5, 1789-1794. (Pubitemid 46794170)
    • (2007) Organic and Biomolecular Chemistry , vol.5 , Issue.11 , pp. 1789-1794
    • Pritz, S.1    Patzel, M.2    Szeimies, G.3    Dathe, M.4    Bienert, M.5
  • 191
    • 0030014882 scopus 로고    scopus 로고
    • (S)-(+)-2-(3′-carboxybicyclo[1.1.1]pentyl)-glycine, a structurally new group I metabotropic glutamate receptor antagonist
    • DOI 10.1021/jm960254o
    • Pellicciari, R.; Raimondo, M.; Marinozzi, M.; Natalini, B.; Costantino, G.; Thomsen C. (S)-(+)-2-(3′-Carboxybicyclo[1.1.1]pentyl)-glycine, a structurally new group I metabotropic glutamate receptor antagonist. J. Med. Chem., 1996, 39, 2874-2876. (Pubitemid 26251024)
    • (1996) Journal of Medicinal Chemistry , vol.39 , Issue.15 , pp. 2874-2876
    • Pellicciari, R.1    Raimondo, M.2    Marinozzi, M.3    Natalini, B.4    Costantino, G.5    Thomsen, C.6
  • 192
    • 0033006689 scopus 로고    scopus 로고
    • 1 receptor antagonist activity
    • DOI 10.1016/S0028-3908(99)00021-0, PII S0028390899000210
    • Mannaioni, G.; Attucci, S.; Missanelli, A.; Pellicciari, R.; Corradetti R.; Moroni, F. Biochemical and electrophysiological studies on (S)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine (CBPG), a novel mGlu5 receptor agonist endowed with mGlu1 receptor antagonist activity. Neuropharmacol., 1999, 38, 917-926. (Pubitemid 29240608)
    • (1999) Neuropharmacology , vol.38 , Issue.7 , pp. 917-926
    • Mannaioni, G.1    Attucci, S.2    Missanelli, A.3    Pellicciari, R.4    Corradetti, R.5    Moroni, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.