Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids

Journal of Medicinal Chemistry

Volumn 46, Issue 14, 2003, Pages 3102-3108

  Conti, Paola ^a   De Amici, Marco ^a   Di Ventimiglia, Samuele Joppolo ^a   Stensbøl, Tine B ^b   Madsen, Ulf ^b   Bräuner Osborne, Hans ^b   Russo, Emilio ^c   De Sarro, Giovambattista ^d   Bruno, Giuseppe ^d   De Micheli, Carlo ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4,5,6,6A TETRAHYDRO 3AH CYCLOPENTA[D]ISOXAZOLE 3,5 DICARBOXYLIC ACID; AMINO ACID; ANTICONVULSIVE AGENT; IONOTROPIC RECEPTOR; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLOADDITION; DRUG ACTIVITY; DRUG CONFORMATION; DRUG SYNTHESIS; MALE; MOUSE; NEUROPROTECTION; NONHUMAN;

AMINO ACIDS, ACIDIC; AMINO ACIDS, DICARBOXYLIC; ANIMALS; ANTICONVULSANTS; CEREBRAL CORTEX; CHO CELLS; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; DICARBOXYLIC ACIDS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; HETEROCYCLIC COMPOUNDS, 2-RING; ISOXAZOLES; MALE; MICE; MICE, INBRED DBA; MOLECULAR CONFORMATION; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; STEREOISOMERISM;

EID: 0038820017     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0308085     Document Type: Article

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